The R18 Polyarginine Peptide Is More Effective Than the TAT-NR2B9c (NA-1) Peptide When Administered 60 Minutes after Permanent Middle Cerebral Artery Occlusion in the Rat by D. Milani, N. W. Knuckey, R. S. Anderton, J. L. Cross, B. P. Meloni

“…The superior neuroprotective efficacy of R18 over TAT-NR2B9c highlights the potential of this polyarginine peptide as a lead candidate for studies in human stroke.…”
Get full text

Antimicrobial Peptides from Porcine Blood Cruor Hydrolysates as a Promising Source of Antifungal Activity by Sara García-Vela, Aurore Cournoyer, Zain Sánchez-Reinoso, Laurent Bazinet

Subjects: Get full text

Trypsin-instructed bioactive peptide nanodrugs with cascading transformations to improve chemotherapy against colon cancer by Can Wu, Xiao Wei Zhang, Manman Wang, Jinpan Sun, Jianfei Chen, Yanbin Guan, Xin Pang

Subjects: “…Bioactive peptide…”
Get full text

The Influence of Cell Isolation and Culturing on Natriuretic Peptide Receptors in Aortic Vascular Smooth Muscle Cells by Christine Rager, Tobias Klöpper, Sabine Tasch, Michael Raymond Whittaker, Betty Exintaris, Andrea Mietens, Ralf Middendorff

Subjects: Get full text

Targeting Interleukin-4 Receptor Alpha by Hybrid Peptide for Novel Biliary Tract Cancer Therapy by Kahori Seto, Junichi Shoda, Tomohisa Horibe, Eiji Warabi, Masayuki Kohno, Toru Yanagawa, Hiroki Bukawa, Yasuni Nakanuma, Koji Kawakami

“…We previously designed novel IL-4Rα-lytic hybrid peptide composed of binding peptide to IL-4Rα and cell-lytic peptide and reported that the designed IL-4Rα-lytic hybrid peptide exhibited cytotoxic and antitumor activity both in vitro and in vivo against the human pancreatic cancer cells expressing IL-4Rα. …”
Get full text

Combination Treatment of C16 Peptide and Angiopoietin-1 Alleviates Neuromyelitis Optica in an Experimental Model by Yuanyuan Zhang, Kewei Tian, Hong Jiang, Beibei Wang, Shu Han

“…We then tested whether the combination of C16, an αvβ3 integrin-binding peptide, and angiopoietin-1 (Ang1), a member of the endothelial growth factor family, could alleviate NMO in the model. …”
Get full text

Study on Fermentation Preparation, Stability, and Angiotensin-Converting Enzyme Inhibitory Activity of Tomato Pomace Peptide by Ying Mu, Ruxianguli Maimaitiyiming, Jingyang Hong, Yu Wang, Yao Zhao, Ruoqing Liu, Liang Wang, Keping Chen, Aihemaitijiang Aihaiti

Subjects: Get full text

Glucagon-Like Peptide-2 Analogue ZP1849 Augments Colonic Anastomotic Wound Healing by Marie Kjaer, Wayne Russell, Peter Schjerling, Elena Cottarelli, Kennet N. Christjansen, Ditte M. G. Olsen, Peter-Martin Krarup, Lene Jessen, Mark Berner-Hansen, Lars N. Jorgensen, Magnus S. Ågren

“…The enteroendocrine hormone glucagon-like peptide- (GLP-) 2 is a potent trophic factor in the gastrointestinal tract. …”
Get full text

UniAMP: enhancing AMP prediction using deep neural networks with inferred information of peptides by Zixin Chen, Chengming Ji, Wenwen Xu, Jianfeng Gao, Ji Huang, Huanliang Xu, Guoliang Qian, Junxian Huang

Subjects: “…Antimicrobial peptides…”
Get full text

Pathogenic Bacterial Detection Using Vertical-Capacitance Sensor Array Immobilized with the Antimicrobial Peptide Melittin by Sun-Mi Lee, Jun-Ho Song, Kyo-Seok Lee, Kyung-Hwa Yoo

Subjects: “…antimicrobial peptides…”
Get full text

Identification and molecular mechanism of angiotensin-converting enzyme inhibitory peptides from Larimichthys crocea titin by Yue Fan, Zhipeng Yu, Wenzhu Zhao, Long Ding, Fuping Zheng, Jianrong Li, Jingbo Liu

Subjects: “…ACE peptide…”
Get full text

Screening of a Novel Peptide Targeting the Proteoglycan-Like Region of Human Carbonic Anhydrase IX by Shoaib Rana, Felix Nissen, Thomas Lindner, Annette Altmann, Walter Mier, Juergen Debus, Uwe Haberkorn, Vasileios Askoxylakis

“…Our findings indicate that PGLR-P1 is a promising lead structure for the development of new peptide-based ligands targeting the PGLR of CA IX and reveal challenges that need to be considered for peptide-related molecular imaging.…”
Get full text

Associates of an Elevated Natriuretic Peptide Level in Stable Heart Failure Patients: Implications for Targeted Management by Aftab Jan, Ian Dawkins, Niamh Murphy, Patrick Collier, John Baugh, Mark Ledwidge, Kenneth McDonald, Chris J. Watson

“…Persistently elevated natriuretic peptide (NP) levels in heart failure (HF) patients are associated with impaired prognosis. …”
Get full text

Bacteriocin-like peptides encoded by a horizontally acquired island mediate Neisseria gonorrhoeae autolysis. by Katy Poncin, Samantha A McKeand, Hayley Lavender, Kacper Kurzyp, Odile B Harrison, Annabell Roberti, Charlotte Melia, Errin Johnson, Martin C J Maiden, David R Greaves, Rachel Exley, Christoph M Tang

“…The nap island in the gonococcus encodes 3 cationic, bacteriocin-like peptides which have no detectable antimicrobial activity. …”
Get full text

Synthesis and Evaluation of Optical and PET GLP-1 Peptide Analogues for GLP-1R Imaging by Babak Behnam Azad, Vanessa Rota, Lihai Yu, Rebecca Mcgirr, André H. St. Amant, Ting-Yim Lee, Savita Dhanvantari, Leonard G. Luyt PhD

“…Insulinomas were clearly visualized by in vivo PET. Reducing the peptide positive charge decreased renal retention as well as tumor uptake. …”
Get full text

Osteogenic differentiation of mesenchymal stem cells in cell-laden culture of self-assembling peptide hydrogels by Faye Fouladgar, Robert Powell, Vishalakshi Irukuvarjula, Akhila Joy, Xiao Li, Neda Habibi

Subjects: Get full text

Preparation and identification novel angiotensin-converting enzyme-inhibitory peptides derived from fish waste by Pakdee Awadsaya, Roytrakul Sittiruk, Wonganu Benjamaporn

“…The result showed that the fractions containing hydrophilic peptides and others containing hydrophobic peptides possessed inhibitory activity against ACE. …”
Get full text

Direct conversion of peptides into diverse peptidomimetics using a transformer-based chemical language model by Atsushi Yoshimori, Jürgen Bajorath

Subjects: “…Peptides…”
Get full text

Current Insight of Peptide-Based Hydrogels for Chronic Wound Healing Applications: A Concise Review by Aifa Asyhira Khairul Nizam, Syafira Masri, Nur Izzah Md Fadilah, Manira Maarof, Mh Busra Fauzi

Subjects: “…peptide-based hydrogel…”
Get full text

Selective peptide bond formation via side chain reactivity and self-assembly of abiotic phosphates by Arti Sharma, Kun Dai, Mahesh D. Pol, Ralf Thomann, Yi Thomann, Subhra Kanti Roy, Charalampos G. Pappas

“…Abstract In the realm of biology, peptide bonds are formed via reactive phosphate-containing intermediates, facilitated by compartmentalized environments that ensure precise coupling and folding. …”
Get full text