Is Helicobacter pylori eradication required for non-steroidal anti-inflammatory drug-associated erosions and ulcers? by A. Ye. Karateyev, Ye. V. Moroz, Anastasia V. Tsurgan, N. V. Gontarenko

“…According to the data of Maastricht consensus (2012), H. pylori infection and NSAIDs are the two major independent etiological factors of peptic ulcer development and upper gastro-intestinal bleeding. …”
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Characterization of Helicobacter Pylori Infection in Patients with Gastric Ulcer by Marcos Félix Osorio Pagola, Magalys Blanca Olivert Cruz, Juan Luís de Pasos Carrazana, Alfredo Basilio Quiñones Ceballos, Mabel Vega Galindo, Anagalys Ortega Alvelay

“…It causes chronic gastritis, peptic ulcer disease, lymphatic proliferative disorders and it is a risk factor for gastric cancer. …”
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Efficacy of parenteral pantoprazole in patients with acute ulcerative gastroduodenal bleeding at high risk of relapse by S. G. Shapovalyants, S. A. Chernyakevich, A. I. Mikhalev, O. I. Yudin, I. V. Babkova, G. N. Storozhuk, Ye. K. Mayat, P. L. Chernyakevich

“…Acute symptomatic ulcers were diagnosed in 14 patients, peptic ulcer – at the other 16. In 17 cases ulcerative bleeding developed on a background of severe concomitant cardio-vascular disease. …”
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The Relationship between H. pylori Infection and Osteoporosis in Japan by Daisuke Asaoka, Akihito Nagahara, Mariko Hojo, Hitoshi Sasaki, Yuji Shimada, Takashi Yoshizawa, Taro Osada, Sumio Watanabe

“…Participants for patient profile, H. pylori infection status, comorbidity, internal medical therapies, lumbar dual-energy X-ray absorptiometry (DXA), and bone turnover marker were collected and upper gastrointestinal endoscopy for reflux esophagitis, hiatal hernia, peptic ulcer disease (PUD), and endoscopic gastric mucosal atrophy (EGA) was performed. …”
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Factors Associated with Recurrent Ulcers in Patients with Gastric Surgery after More Than 15 Years: A Cross-Sectional Single-Center Study by Monica Pantea, Anca Negovan, Claudia Banescu, Simona Bataga, Radu Neagoe, Simona Mocan, Mihaela Iancu

“…Biliary reflux and alcohol consumption, but not Helicobacter pylori infection or gastrotoxic drug, seem to be the most important predictors for ulcer recurrence in patients with gastric surgery for peptic ulcer after more than 15 years.…”
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Efficacy and Safety of the Triple Therapy Containing Ilaprazole, Levofloxacin, and Amoxicillin as First-Line Treatment in Helicobacter pylori Infections by Hyo Jun Ahn, Dong Pil Kim, Myeong Su Chu, Hyeon Jeong Yun, Seok-Hwan Kim, Seung Woo Lee, Dong Soo Lee

“…Demographic factors such as age, gender, body mass index (BMI), alcohol, smoking, hypertension, diabetes mellitus, and peptic ulcer did not affect the eradication rate. However, multivariate analysis showed that overweight patients and patients with cerebrovascular accident (CVA) had a significantly lower eradication rate than patients with normal BMI and without CVA. …”
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Chitosan Nanoparticles for Enhanced Immune Response and Delivery of Multi-Epitope <i>Helicobacter pylori</i> Vaccines in a BALB/c Mouse Model by Rita Amaral, Tomás Concha, Jorge Vítor, António J. Almeida, Cecília Calado, Lídia M. Gonçalves

“…<b>Background/Objectives</b>: <i>Helicobacter pylori</i> is the leading cause of chronic gastritis, peptic ulcer, gastric adenocarcinoma, and mucosal-associated lymphoma. …”
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Population- and Gender-Based Investigation for Prevalence of Helicobacter pylori in Dhamar, Yemen by Dhary A. Almashhadany, Sara M. Mayas, Hero I. Mohammed, Abdulwahed A. Hassan, Izhar U. H. Khan

“…Among 35 species of genus Helicobacter, H. pylori is the most common causative agent of human gastritis, peptic ulcer, and gastric cancer. The infection can spread through direct human-to-human contact, fecal–oral route, and contaminated water. …”
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Helicobacter pylori infection diagnostics and choice of eradication treatment: results of inquiry of doctors from different regions of Russian Federation by N. N. Dekhnich, R. S. Kozlov, O. A. Sablin, Ye. A. Prischepova

“…Primary diagnostics of H. pylori infection is carried out at peptic ulcer and chronic gastritis by 85 and 84% of surveyed doctors, at GERD - by 59.4%, at NSAID -related gastropathy - by 32%, at MALT lymphoma by 32%, at stomach cancer - by 30.7% and at autoimmune thrombocytopenia - by 16.8% respectively. …”
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Indicators Of Morbidity And Mortality From Diseases of the Digestive System in the Krasnodar Krai and the Quality of Medical Care for Gastroenterological Patients by N. V. Korochanskaya, V. M. Durleshter, O. V. Kovalevskaya, S. N. Serikova, K. I. Popandopulo

“…The pathology of the pancreas takes the second place (13.5 %). The peptic ulcer of the stomach, duodenum and “other diseases of the digestive system” (8.8 % and 7.7 %, respectively) are represented in almost equal shares. …”
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Clinical Risk Factors for Gastroduodenal Ulcer in Romanian Low-Dose Aspirin Consumers by Anca Negovan, Mihaela Iancu, Valeriu Moldovan, Septimiu Voidazan, Simona Bataga, Monica Pantea, Kinga Sarkany, Cristina Tatar, Simona Mocan, Claudia Banescu

“…According to our multivariate regression analysis results, history of peptic ulcer (OR 3.07, 95% CI 1.06–8.86), cotreatment with NSAIDs (OR 8, 95% CI 2.09–30.58) or anticoagulants (OR 4.85, 95% CI 1.33–17.68), male gender (OR 5.2, 95% CI 1.77–15.34), and stroke (OR 7.27, 95% CI 1.40–37.74) remained predictors for ulcer on endoscopy. …”
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Modern Approaches to <i>H. pylori</i> Eradication Therapy in Adults (Literature Review and Resolution of Experts Council) by V. Т. Ivashkin, A. I. Ulyanin, I. V. Mayev, R. S. Kozlov, M. A. Livzan, S. R. Abdulkhakov, O. P. Alekseyeva, S. A. Alekseyenko, D. S. Bordin, N. N. Dekhnich, N. V. Korochyanskaya, T. L. Lapina, E. A. Poluektova, V. I. Simanenkov, A. S. Trukhmanov, I. B. Khlynov, V. V. Tsukanov, A. A. Sheptulin

“…H. pylori infection is the main etiological factor of gastritis, peptic ulcer, and gastric cancer. Eradication of H. pylori is recognized as a necessary measure to reduce the incidence of these diseases. …”
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Gambaran Esofagogastroduodenoskopi Pasien Hematemesis dan atau Melena di RSUP M Djamil Padang Periode Januari 2010 - Desember 2013 by Fadhil Alfino Azmi, 1, SSaptino Miro, Detty Iryani

“…The most common etiology that often being reported are esophageal varices, peptic ulcer, erosive gastritis, etc. The objective of this study was to determine the frequency of esophagogastroduodenoscopy(EGD) findings in patients with hematemesis and/or melena in M Djamil Hospital Padang. …”
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Prevalence of Helicobacter pylori infection and its Associated Risk Factors among symptomatic Residents of Sulaimani city, Kurdistan region, Iraq, 2020 by Seerwan Hama Rashid Ali, Sabiha Sharif Salih, Taib Ahmed Hama Sour, Goran Mohammad Raouf, Araz Latif Rahim

“…Many of the studies showed that infection by H. pylori can cause some important gastrointestinal illness, such as peptic ulcer, chronic gastritis, gastric adenocarcinoma and mucosa associated lymphoid tissue lymphoma. …”
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Determinants of Anemia among Pregnant Women at Public Hospitals in West Shewa, Central Ethiopia: A Case-Control Study by Berhanu Senbeta Deriba, Elias Teferi Bala, Gizachew Abdissa Bulto, Tinsae Abeya Geleta, Agumas Fentahun Ayalew, Addis Adera Gebru, Habtamu Oljira Desta, Mengistu Benayew Shiferaew, Lidya Zerihun Sahile

“…Family size >5 (AOR = 2.95, 95% CI: 1.34–6.50), peptic ulcer diseases (PUD) (AOR = 2.85, 95% CI: 1.14–7.13), having the previous history of abortion (AOR = 2.84, 95% CI: 1.08–7.47), birth interval <2 years (AOR = 2.61, 95% CI: 1.20–5.70), antepartum hemorrhage (APH) (AOR = 6.05, 95% CI: 1.95–18.81), and not using latrine (AOR = 3.45, 95% CI: 1.30–9.24) were the identified determinants of anemia. …”
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Helicobacter pylori infection at long-term treatment by proton pump inhibitors for acid-related diseases (Literature review and resolution of Advisory council, March 22, 2018) by V. T. Ivashkin, I. V. Mayev, R. A. Abdulkhakov, O. P. Alekseyeva, S. A. Alekseyenko, A. Yu. Baranovsky, Ye. K. Baranskaya, I. L. Klyaritskaya, N. V. Korochanskaya, Yu. A. Kucheryavy, T. L. Lapina, M. F. Osipenko, V. I. Simanenkov, G. N. Tarasova, A. S. Trukhmanov, I. B. Khlynov, A. A. Sheptulin

“…The presence of GERD could not prevent infection eradication in the presence of other indications (e.g., peptic ulcer, chronic gastritis). Monotherapy by proton pump inhibitors (PPI) in H. pylori-positive patients with GERD may lead to progression of gastric corpus atrophy that can be regarded as risk factor for stomach cancer development. …”
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Prevalence and Risk Factors of Helicobacter pylori Infection among Children Aged 1 to 15 Years at Holy Innocents Children’s Hospital, Mbarara, South Western Uganda by Phoebe Aitila, Michael Mutyaba, Simon Okeny, Maurice Ndawula Kasule, Rashid Kasule, Frank Ssedyabane, Benson Okongo, Richard Onyuthi Apecu, Enoch Muwanguzi, Caesar Oyet

“…The infection is generally acquired during childhood but can remain asymptomatic, with long-term clinical sequelae including gastritis, peptic ulcer disease, and stomach cancer. Methods. The study was approved by Institutional Review Committee of Mbarara University of Science and Technology. …”
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Alcohol abuse in gastroenterological patients by M. V. Mayevskaya, I. G. Bakulin, A. A. Chirkov, Ye. O. Lyusina, V. D. Lun’Kov

“…Thirty-two percent of patients had liver cirrhosis of toxic and viral etiology, 18% had chronic toxic and viral hepatitis, 11% - non-alcoholic fatty liver disease and various biliary diseases respectively, chronic pancreatitis and chronic gastritis subgroups represented 6% of all patients each, irritable bowel syndrome and gastroesophageal reflux disease - 4% each, primary biliary cirrhosis, hepatocellular carcinoma, stomach and duodenal peptic ulcer disease - 2%. According to doctors opinion strong correlation between between alcohol consumption and disease development was present in 22,2% of men and 8,7% of women. …”
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Clinical Practice Guidelines of Russian Gastroenterological Association, Scientific Society for the Clinical Study of Human Microbiome, Russian Society for the Prevention of Non-Co... by V. T. Ivashkin, T. L. Lapina, I. V. Maev, O. M. Drapkina, R. S. Kozlov, A. A. Sheptulin, A. S. Trukhmanov, S. R. Abdulkhakov, O. P. Alekseeva, S. A. Alekseenko, D. N. Andreev, D. S. Bordin, N. N. Dekhnich, I. L. Klyaritskaya, N. V. Korochanskaya, M. F. Osipenko, E. A. Poluektova, A. S. Sarsenbaeva, V. I. Simanenkov, A. V. Tkachev, A. I. Ulyanin, I. B. Khlynov, V. V. Tsukanov

“…Indications, for obligatory anti-Helicobacter therapy include peptic ulcer, gastric MALT lymphoma, early gastric cancer (EGC) with endoscopic resection. …”
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Immunization with a Synthetic Helicobacter pylori Peptide Induces Secretory IgA Antibodies and Protects Mice against Infection by David Espinosa-Ramos, Diana Caballero-Hernández, Ricardo Gomez-Flores, Armando Trejo-Chávez, Luis Jerónimo Pérez-Limón, Myriam Angélica de la Garza-Ramos, Reyes Tamez-Guerra, Patricia Tamez-Guerra, Cristina Rodriguez-Padilla

“…Helicobacter pylori is a spiral Gram-negative bacterium associated with inflammation of the gastric mucosa, peptic ulcer, and gastric adenocarcinoma, whose treatment has failed due to antibiotic resistance and side effects. …”
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