Evaluating the Efficacy of Combined Intravaginal Estriol Therapy and Kegel Exercises in Managing Menopausal Atrophic Vulvovaginitis by Lucian Șerbănescu, Vadym Rotar, Dragoș Brezeanu, Sebastian Mirea, Elena-Valentina Ionescu, Paris Ionescu

“…Non-hormonal adjunctive treatments, such as pelvic floor exercises (e.g., Kegel exercises), are being explored to enhance clinical outcomes. …”
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Provocative tests of anal sphincter function correlate with symptoms and subtypes of faecal incontinence by John McLaughlin, Dipesh H Vasant, Asbjørn Mohr Drewes, Abhiram Sharma, Matthew Davenport, Edward Kiff, Karen Telford, Alexander O'Connor, Donghua Liao, Niels Klarskov

“…This study uniquely explores all three methods in correlation with FI symptoms and subtypes.Methods This was a prospective observational study of patients with FI attending a tertiary pelvic floor unit between August 2022 and January 2024. …”
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Comprehensive analysis of the circRNA expression profile and circRNA-miRNA-mRNA network in pelvic organ prolapse by Qian Wang, Zuoxi He, Lisha Ding, Yuqing Liu, Xiaoli Zhang, Tao Wang, Xiaoyu Niu

“…Pelvic organ prolapse (POP) is a common gynecological disease caused by pathological defects, lesions, or mechanical weakening of the support structures of the pelvic floor. However, its pathogenesis is unclear. Circular RNAs (circRNAs) are covalently closed, endogenous biomolecules, which are thought to play an important role on skeletal muscle development by regulating gene expression. …”
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Prediction model study focusing on eHealth in the management of urinary incontinence: the Personalised Advantage Index as a decision-making aid by Huibert Burger, Henk van der Worp, Marco H Blanker, Marjolein Y Berger, Anne Martina Maria Loohuis, Nienke Wessels, Janny Dekker, Alec GGA Malmberg

“…Of the 350 screened women, 262 were eligible and randomised to app-based treatment or care as usual; 195 (74%) attended follow-up.Predictors Literature review and expert opinion identified 13 candidate predictors, categorised into two groups: Prognostic factors (independent of treatment type), such as UI severity, postmenopausal state, vaginal births, general physical health status, pelvic floor muscle function and body mass index; and modifiers (dependent on treatment type), such as age, UI type and duration, impact on quality of life, previous physical therapy, recruitment method and educational level.Main outcome measure Primary outcome was symptom severity after a 4-month follow-up period, measured by the International Consultation on Incontinence Questionnaire the Urinary Incontinence Short Form. …”
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Investigation and analysis on the status quo of nurses' knowledge of urinary incontinence and their training needs in the region (上海市某区域护士尿失禁知识认知现状与培训需求的调查分析)... by YUAN Hongyan (袁红艳), XU Fanglei (许方蕾), TANG Ailing (汤爱玲), GE Yan (葛颜), DONG Li (董里)

“…Nurses in level II hospitals (29. 82%) preferred to strengthen training on functional exercise, such as rehabilitation and guidance of pelvic floor muscles. Nurses in community health service centers (22. 56%) were more concerned with the care of patients with urinary incontinence and the cooperation of family members. …”
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E_N_T_R_O_P_Y: Monocentric analysis of rectal cancer radio-chemotherapy treatment in patients of young age by E. Meldolesi, A. Nicolì, N. Dinapoli, G. Chiloiro, A. Romano, R. Menghi, R. Persiani, F. Pacelli, C. Coco, C. Ratto, S. Manfrida, L. Boldrini, B. Corvari, M.A. Gambacorta

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Systematic identification of secondary bile acid production genes in global microbiome by Yuwei Yang, Wenxing Gao, Ruixin Zhu, Liwen Tao, Wanning Chen, Xinyue Zhu, Mengping Shen, Tingjun Xu, Tingting Zhao, Xiaobai Zhang, Lixin Zhu, Na Jiao

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The use of patient-generated health data in the management of low anterior resection syndrome: a qualitative study by Olivia Monton, Olivia Monton, Allister Smith, Sarah Sabboobeh, Marie Demian, Julie Cornish, Steven D. Wexner, Peter Christensen, Peter Christensen, Amandeep Ghuman, Liliana G. Bordeianou, Liliana G. Bordeianou, Liliana G. Bordeianou, Celia Keane, Celia Keane, Syed Husain, Alessandra Gasior, Alessandra Gasior, Natalie Leon, Julie Savard, Lieba R. Savitt, Margit Majgaard, Gitte Kjær Sørensen, Melanie Mills, Fateme Rajabiyazdi, Marylise Boutros, Marylise Boutros

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