HER-SAFE study design: an open-label, randomised controlled trial to investigate the safety of withdrawal of pharmacological treatment for recovered HER2-targeted therapy-related c... by Robin Chung, James C Moon, Alexander R Lyon, Charlotte H Manisty, Muhummad Sohaib Nazir, Malcolm Walker, Peter Kellman, Benjamin Dowsing, Daniel Chen, Jessica Artico, Mark Westwood, Hakim-Moulay Dehbi, Rebecca Roylance, Tom Crake, Peter Schmid, Arjun Ghosh, Maria Sol Andres, Joanna Pedra, Orla Worn

“…The results will be disseminated in peer-reviewed scientific journals.Trial registration number NCT05880160.…”
Get full text

Exercise-based cardiac rehabilitation for patients with atrial fibrillation receiving catheter ablation: protocol for a feasibility randomised controlled trial (RCT) with embedded... by Gregory Y H Lip, Helen Jones, Mark T Mills, Dhiraj Gupta, Lawrence Foweather, Benjamin JR Buckley, Charlotte Fitzhugh

“…Results will be published in peer-reviewed journals and presented at national and international scientific meetings, and summaries will be communicated to participants.Trial registration number Clinicaltrials.gov identifier: NCT06401148.…”
Get full text

Discrepancies in reported results between trial registries and journal articles for AI clinical researchResearch in context by Zixuan He, Lan Yang, Xiaofan Li, Jian Du

“…There were more results in trial registries than in articles, but researchers showed a clear preference for rapid dissemination of results through peer-reviewed articles (37.6% published within one year) over trial registries (15.8%). …”
Get full text

Initial treatment of steroid-sensitive idiopathic nephrotic syndrome in children with mycophenolate mofetil versus prednisone: protocol for a randomised, controlled, multicentre tr... by Burkhard Toenshoff, Martin Konrad, Steffen Luntz, Anja Sander, Peter F Hoyer, Rasmus Ehren, Marcus R Benz, Jorg Doetsch, Alexander Fichtner, Jutta Gellermann, Dieter Haffner, Britta Höcker, Bärbel Kästner, Markus J Kemper, Uwe Querfeld, Lutz T Weber

“…Our findings will be submitted to major international paediatric nephrology and general paediatric conferences and submitted for publication in a peer-reviewed, open-access journal.Trial registration number DRKS0006547; EudraCT2014-001991-76; Pre-result.Date of registration 30 October 2014; 24 February 2017.…”
Get full text

Detection of exhaled methane levels for monitoring trauma-related haemorrhage following blunt trauma: study protocol for a prospective observational study by Péter Jávor, Ferenc Rárosi, Tamara Horváth, László Török, Endre Varga, Petra Hartmann

“…It is in data collection phase, theresults will be shared with the scientific community through publication in a peer-reviewed journal.Trial registration number NCT04987411; ClinicalTrials.gov, registered on 27 July 2021.…”
Get full text

Blinding assessment in randomised sham-controlled trials of acupuncture:protocol for a systematic survey by Ling Li, Xin Sun, Jiali Liu, Minghong Yao, Yong Fu, Jiahui Yang, Xiaochao Luo

“…The findings of this study will be disseminated through peer-reviewed publications, conference presentations and condensed summaries for clinicians, health policymakers and guideline developers regarding the design, conduct, analysis and interpretation of blinded assessment of sham acupuncture RCTs.Study registration Open Science Framework (https://doi.org/10.17605/OSF.IO/B3U7K).…”
Get full text

Protocol for faecal microbiota transplantation in irritable bowel syndrome: the MISCEAT study – a randomised, double-blind cross-over study using mixed microbiota from healthy dono... by Lenka Kramna, Ondrej Cinek, Jakub Hurych, Jiri Vejmelka, Lucie Hlinakova, Vladyslav Larionov, Michal Kulich, Pavel Kohout

“…Secondary outcomes are IBS-SSS at 2 weeks after the intervention and 32 weeks compared with placebo and changes in the number of loose stools, Bristol stool scale, abdominal pain and bloating, anthropometric parameters, psychological evaluation and the gut microbiome composition.Ethics and dissemination The study was approved by the Ethics Committee of Thomayer University Hospital, Czechia (G-18-26); study results will be published in peer-reviewed journals and presented at international conferences and patient group meetings.Trial registration number NCT04899869.…”
Get full text

Minimal clinical data sets for spine-related musculoskeletal disorders in primary care and outpatient settings: a scoping review protocol by Pierre Côté, Andrea C Tricco, Cesar A Hincapié, Léonie Hofstetter, Jérémie Mikhail, Isabelle Pagé

“…Results will be shared through peer-reviewed publication and presentations at relevant conferences.Protocol registration number https://osf.io/fkw5b.…”
Get full text

Nutrient Profiling Models in Low- and Middle-Income Countries Considering Local Nutritional Challenges: A Systematic Review by Marie Tassy, Ries van Dijk, Alison L Eldridge, Tsz Ning Mak, Adam Drewnowski, Edith JM Feskens

“…This study reviewed government-endorsed NPMs implemented in LMICs and assessed their key components in relation to country-specific nutritional challenges. The peer-reviewed and grey literature were systematically reviewed to identify government-endorsed NPMs implemented in LMICs to promote healthier choices among adults. …”
Get full text

Impact of prior SARS-CoV-2 infection and COVID-19 vaccination on the subsequent incidence of COVID-19: a multicentre prospective cohort study among UK healthcare workers – the SIRE... by Nick Andrews, Mary Ramsay, Maria Zambon, Victoria Hall, Sarah Wallace, Susan Hopkins, Jean Timeyin, Tim J G Brooks, Amoolya Vusirikala, Meera Chand, Andre Charlett, Sakib Rokadiya, Colin S Brown, Madhumita Shrotri, Peter D Kirwan, Michele Cole, Natalie Gillson, Ana Atti, Sarah Foulkes, Andrew Taylor-Kerr, Blanche Oguti, Jasmin Islam

“…Participants gave informed consent before taking part in the study.Regular reports to national and international expert advisory groups and peer-reviewed publications ensure timely dissemination of findings to inform decision making.Trial registration number ISRCTN11041050.…”
Get full text

Accepting your Body after Cancer (ABC), a group-based online intervention for women treated for breast cancer: study protocol for a feasibility randomised controlled trial by Sarah Byford, Abigail Jones, Shelley Potter, Paul White, Diana Harcourt, Helena Lewis-Smith, Patricia Fairbrother

“…The findings will be disseminated to academic and health professionals via a peer-reviewed publication and presentations at relevant conferences. …”
Get full text

Effectiveness of a web-based virtual journal club to promote medical education (Web-Ed): protocol of a multicentre pragmatic randomised trial by Mohamed Abdelrahman, Neil Cowan, Meera Ramcharn, Bassel H Al Wattar, William Parry-Smith, Sarah McRobbie, Michael Rimmer, Nagla Elfaki, Cheryl Dunlop, Damien Coleburt, Olivia Raglan, Jhia Jiat Teh, Maria Fisher, Nilaani Murugesu, Yazid Jibrel, Matthew Wood

“…The trial results will be published in peer-reviewed journals and presented at relevant scientific conferences. …”
Get full text

Linking weather and climate information services (WCIS) to Climate-Smart Agriculture (CSA) practices by Tafadzwanashe Mabhaudhi, Tinashe Lindel Dirwai, Cuthbert Taguta, Aidan Senzanje, Wuletawu Abera, Ajit Govid, Elliott Ronald Dossou-Yovo, Ermias Aynekulu, Vimbayi Grace Petrova Chimonyo

“…It involved the search of the Scopus and Web of Science databases for peer-reviewed articles, books, and grey literature focussed on the global south. …”
Get full text

Prediction of postoperative myocardial injury in patients undergoing laparoscopic pheochromocytoma/paraganglioma resection: protocol for an ambispective cohort study by Yuguang Huang, Yuelun Zhang, Ling Lan, Yi Zhang, Ye Ma, Le Shen, Yifei Zhao, Yaohan Li

“…We aim to publish and disseminate the findings in peer-reviewed journals and at scientific conferences.Trial registration number NCT05752773.…”
Get full text

Acupressure intervention for children: A scoping review by Sri Ramdaniati, Mei Neni Sitaresmi, Fitri Haryanti, Arief Tarmansyah Iman

“…The inclusion criteria were original peer-reviewed articles in English or Indonesian that used acupressure as an intervention for children in any setting from 1991 until March 2022 and were updated until March 2024. …”
Get full text

Non-pharmacological interventions for primary hypertension: a systematic review and network meta-analysis protocol by Tao Xu, Fan-rong Liang, Qifu Li, Taipin Guo, Ziwen Chen, Yun-Jie Shu, Xueli Zhou

“…The results will be published in peer-reviewed journals.PROSPERO registration number CRD42023451073.…”
Get full text

Synovial biomarkers in the diagnosis of post-traumatic osteoarthritis following anterior cruciate ligament and meniscus injuries: protocol for a systematic review by Helena Donato, Fernando Fonseca, João Pedro Oliveira, João Castro Mendes, José Casanova, Alexandrina Ferreira Mendes

“…The findings from this work will be submitted for publication in a peer-reviewed journal and presented at relevant academic conferences. …”
Get full text

The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole (TIPAL): study protocol for a randomised placebo-controlled mult... by Toby M Maher, A John Simpson, Anthony Cahn, David Thickett, Luke Vale, Allan B Clark, Nazia Chaudhuri, Ian Forrest, Lisa G Spencer, Christopher Ward, Stephen Jones, Ganesh Raghu, Andrew M Wilson, Helen Parfrey, Megan Jones, Matthew Hammond, Jaclyn Ann Smith, Shajahan Wahed

“…Trial results will be published in a peer-reviewed journal upon completion.Trial registration number ISRCTN13526307; ClinicalTrials.gov NCT04965298.…”
Get full text

Improving the Detection, Assessment, Management and Prevention of Delirium in Hospices (the DAMPen-D study): protocol for a co-design and feasibility study of a flexible and scalab... by Najma Siddiqi, Chao Huang, Maureen Twiddy, Miriam Johnson, Margaret Ogden, Kathryn Sartain, Imogen Featherstone, Jason Boland, Mark Pearson, Catriona Jackson, Gillian Jackson

“…A results paper will be submitted to an open access peer-reviewed journal and a lay summary shared with study site staff and stakeholders.Trial registration number ISRCTN55416525.…”
Get full text

Risk Factors of Hemophagocytic Lymphohistiocytosis in Adults with Fever of Unknown Origin: A Retrospective Study by Tian F, Xie N, Sun W, Zhang W, Zhang W, Chen J, Ruan Q, Song J

Get full text