Utilizing Targeted Next-Generation Sequencing for Rapid, Accurate, and Cost-Effective Pathogen Detection in Lower Respiratory Tract Infections by Qin L, Liang M, Song J, Chen P, Zhang S, Zhou Y, Li H, Tang J, Ma Y, Yang B, Xu J, Zhang J

“…Lisha Qin,1,* Mengyuan Liang,1,2,* Jianping Song,1,* Ping Chen,1,* Shujing Zhang,3,* Yaya Zhou,1 Hui Li,1 Jian Tang,1 Yanling Ma,1 Bohan Yang,1 Juanjuan Xu,1 Jianchu Zhang1 1Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine, Zhengzhou University People’s Hospital, Henan Provincial People’s Hospital, Zhengzhou, People’s Republic of China; 3Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jianchu Zhang, Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China, Tel +86-13971445469, Email zsn0928@163.comObjective: To evaluate the diagnostic performance and clinical impact of targeted next-generation sequencing (tNGS) in patients with suspected lower respiratory tract infections.Methods: Following propensity score matching, we compared the diagnostic performances of tNGS and metagenomic next-generation sequencing (mNGS). …”
Get full text

Performance of a Toric, Monthly, Soft Contact Lens in Digital Device Users by Pucker AD, Franklin QX, Perkins AF, May K, Kannarr SR, Bromley M, Lievens C

“…Andrew D Pucker,1 Quentin X Franklin,2 Amy F Perkins,3 Kristopher May,4 Shane R Kannarr,5 Morgan Bromley,3 Chris Lievens3 1Eminent Ophthalmic Services, Milledgeville, GA, USA; 2Department of Pediatrics, University of Birmingham, Birmingham, AL, USA; 3Research Department, Southern College of Optometry, Memphis, TN, USA; 4Coldwater Vision Center, Coldwater, MS, USA; 5Kannarr Eye Care, Pittsburg, KS, USACorrespondence: Chris Lievens, Southern College of Optometry, 1245 Madison Ave, Memphis, TN, 38104, USA, Tel +1 (901) 722-3330, Email clievens@sco.eduPurpose: To determine the performance of TOTAL30 for Astigmatism (T30fA; Alcon; Fort Worth, TX, USA) contact lenses (CLs) in existing CL wearers who are also frequent digital device users.Methods: This 1-month, 3-visit study recruited adult, 18- to 40-year-old subjects who were required to use daily digital devices for at least 8 hours per day. …”
Get full text

Effect of “Helping Babies Breathe” Training on Ethiopian Undergraduate Midwifery Students’ Knowledge and Skills in Neonatal Resuscitation at Public Universities: A Non-Randomized Q... by Endalew Gemechu Sendo, Girum Sebsibe Teshome, Wegnesh Kelbessa Jirata, Lemi Abebe Gebrewold, Rahel Endalew Gemechu

“…Helping Babies Breathe (HBB) is a global initiative launched by the American Academy of Pediatrics (AAP) in 2010, aimed at reducing neonatal mortality by addressing birth asphyxia, a leading cause of newborn deaths worldwide. …”
Get full text

The Use of Electronic Consent (eConsent) Within the Ketamine for Long-Lasting Pain Relief After Surgery (KALPAS) Multicenter Trial by Doan LV, Burr J, Perez R, Martinez H, Cuevas R, Watt K, Wang J

“…Lisa V Doan,1,2 Jeri Burr,3 Raven Perez,1,2 Hamleini Martinez,1,2 Randy Cuevas,1,2 Kevin Watt,3 Jing Wang1,2,4 1Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Grossman School of Medicine, New York, NY, USA; 2Interdisciplinary Pain Research Program, New York University Grossman School of Medicine, New York, NY, USA; 3Department of Pediatrics, University of Utah, Salt Lake City, UT, USA; 4Department of Neuroscience and Physiology, New York University Grossman School of Medicine, New York, NY, USACorrespondence: Lisa V Doan; Jing Wang, Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Grossman School of Medicine, New York, NY, USA, Email Lisa.doan@nyulangone.org; jing.wang2@nyulangone.orgBackground: The informed consent process has traditionally taken place in person. …”
Get full text

Cognitive functioning and work-related outcomes of non-central nervous system cancer survivors: protocol for a systematic review with meta-analysis by Sofia Fernandes, Ana F Oliveira, Juliana D Reis, Ana Torres, Isabel M Santos, Diane Von Ah

Get full text

Estimating health state utilities for aromatic L-amino acid decarboxylase deficiency (AADCd) in the United States by Berrin Monteleone, Katie Forster, Gin Nie Chua, Rongrong Zhang, Andrew Lloyd, Paul Castellano, Ioannis Tomazos

Get full text

Efficacy Analysis of Hypofractionated Radiotherapy for Oligometastatic Tumors: A Retrospective Study by Qian Sun MD, Hanqing Zhao MS, Xianwen Zhang MS, Suli Zhang MS, Zelai He MD, Gengming Wang MD, Hao Jiang MS, Aili Xuan MS, Xianming Li MD

Get full text

Integrating bioinformatics and machine learning to identify AhR-related gene signatures for prognosis and tumor microenvironment modulation in melanoma by Qianru Li, Qianru Li, Heli Li

Get full text

Patient experience with eosinophilic esophagitis symptoms and impacts on daily life based on in-trial qualitative interviews by Calvin N. Ho, Harald Fjällbrant, Evan S. Dellon, Cecilio Santander, Marc E. Rothenberg, Julie Bailey, Shehan McFadden, Jason Ritchie

Get full text

Genetic Variations in the Kir6.2 Subunit (KCNJ11) of Pancreatic ATP-Sensitive Potassium Channel Gene Are Associated with Insulin Response to Glucose Loading and Early Onset of Type... by Yi-Der Jiang, Lee-Ming Chuang, Dee Pei, Yann-Jinn Lee, Jun-Nan Wei, Fung-Chang Sung, Tien-Jyun Chang

Get full text

Intrauterine metformin exposure and adiposity outcomes in children: a systematic review and meta-analysis by George Tomlinson, Jill Hamilton, Kellie E Murphy, Jennifer Fu, Najla Tabbara, Denice S Feig

Get full text

Identification and Functional Characterization of P159L Mutation in in a Family with Maturity-Onset Diabetes of the Young 5 (MODY5) by Eun Ky Kim, Ji Seon Lee, Hae Il Cheong, Sung Soo Chung, Soo Heon Kwak, Kyong Soo Park

Get full text

Cryoablation for advanced non-small cell lung cancer: a protocol for a systematic review by Dan Wang, Yu Chen, Hua Duan, Shu-Yue Zheng, Chufan Luo, Xueni Fang, Haoyue Pang, Man Wang, Tian Zhou, Quanwang Li, Kaiwen Hu

Get full text

Advances in Cardiovascular Multimodality Imaging in Patients with Marfan Syndrome by Marco Alfonso Perrone, Sara Moscatelli, Giulia Guglielmi, Francesco Bianco, Deborah Cappelletti, Amedeo Pellizzon, Andrea Baggiano, Enrico Emilio Diviggiano, Maria Ricci, Pier Paolo Bassareo, Akshyaya Pradhan, Giulia Elena Mandoli, Andrea Cimini, Giuseppe Caminiti

Get full text

Built environment change for injury prevention: insights from public health professionals across public health units in Ontario, Canada by Emily McCullogh, Alison Macpherson, Daniel W. Harrington, Ian Pike, Brent Hagel, Claire Buchan, Pamela Fuselli, Sarah A. Richmond

Get full text

Simple hypertrophic tonsils have more active innate immune and inflammatory responses than hypertrophic tonsils with recurrent inflammation in children by Qun Huang, Hu Hua, Wei Li, Xi Chen, Lei Cheng

Get full text

Differentiating the cognitive development of early-term births in infants and toddlers: a cross-sectional study in China by Jing Hua, Jie Sun, Zhijuan Cao, Xiaotian Dai, Senran Lin, Jialin Guo, Guixiong Gu, Wenchong Du

Get full text

Oral dydrogesterone versus oral micronized progesterone in threatened miscarriage: protocol paper for a randomized controlled trial by Alka Kriplani, Gouri Shankar Kamilya, T Ramani Devi, Ashima Taneja, Amol Pawar, Gayathri Karthik Nagesh, Tapan Pattanaik, Tanusree Gupta, Mahima Jain, Monjori Mitra

Get full text

Towards Elimination of Mother-to-Child Transmission of HIV: The Impact of a Rapid Results Initiative in Nyanza Province, Kenya by Lisa L. Dillabaugh, Jayne Lewis Kulzer, Kevin Owuor, Valerie Ndege, Arbogast Oyanga, Evelyne Ngugi, Starley B. Shade, Elizabeth Bukusi, Craig R. Cohen

Get full text

Comparison of Chest Computed Tomography (CT) Imaging Patterns and Severity among COVID-19 Patients during the First and Fourth Waves in Addis Ababa, Ethiopia by Lensa Million Baharu, Amir Alwan, Seife Teferi Dellie, Tesfaye Kebede Legesse, Kibruyisfaw Weldeab Abore

Get full text