Dendrobium species regulate energy homeostasis in neurodegenerative diseases: a review by Feixuan Wang, Jingqiong Wan, Yangzhen Liao, Shangyu Liu, Yuan Wei, Zhen Ouyang

“…The impairment of energy homeostasis is recognized as a key pathophysiological basis for brain metabolic disorders and related neurodegenerative diseases. …”
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Endoplasmic Reticulum Stress-Associated Lipid Droplet Formation and Type II Diabetes by Xuebao Zhang, Kezhong Zhang

“…However, much work remains to be done in understanding the mechanism by which ER stress response regulates LD formation and the pathophysiologic role of ER stress-associated LD in metabolic disease. …”
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Topical Steroid Withdrawal in Atopic Dermatitis: Patient-reported Characterization from a Swedish Social Media Questionnaire by Mikael Alsterholm, Maja af Klinteberg, Sophie Vrang, Gunnthorunn Sigurdardottir, MariHelen Sandström Falk, Alexander Shayesteh

“…Topical steroid withdrawal (TSW) is described as an adverse reaction to topical glucocorticoids (TGCs). A pathophysiological mechanism has not been identified. There are no diagnostic criteria. …”
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Unveiling the molecular and cellular links between obstructive sleep apnea-hypopnea syndrome and vascular aging by Wei Liu, Le Zhang, Wenhui Liao, Huiguo Liu, Wukaiyang Liang, Jinhua Yan, Yi Huang, Tao Jiang, Qian Wang, Cuntai Zhang, Peifang Wei

“…The accumulation and combination of these features may underlie the pathophysiological link between OSAHS and VA, but the exact mechanisms by which OSAHS affects VA may require further investigation. …”
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Non-invasive Mechanical Ventilation in Lung Cancer: Physiological Principles and Clinical Utilization in Surgical and Non-surgical Settings by Marco Cascella, Antonio M. Esquinas

“…Since both non-invasive positive pressure ventilation modes, including BiLevel positive airway pressure and continuous positive airway pressure, address the underlying pathophysiological mechanisms that contribute to postoperative respiratory failure, the proactive and early integration of NIMV has the potential to significantly enhance gas exchange and overall respiratory performance in meticulously chosen patients within the perioperative phase. …”
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The Interstitial Lymphatic Peritoneal Mesothelium Axis in Portal Hypertensive Ascites: When in Danger, Go Back to the Sea by M. A. Aller, I. Prieto, S. Argudo, F. de Vicente, L. Santamaría, M. P. de Miguel, J. L. Arias, J. Arias

“…The splanchnic interstitium, the mesenteric lymphatics, and the peritoneal mesothelium seem to create an inflammatory pathway that could have a key pathophysiological relevance in the production of the portal hypertension syndrome complications. …”
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Role of calpain system in meat tenderness: A review by Z.F. Bhat, James D. Morton, Susan L. Mason, Alaa El-Din A. Bekhit

“…These ubiquitous proteases are also present in mitochondria and play important roles in a variety of pathophysiological conditions including apoptotic and necrotic cell death phenomena. …”
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Surgical Tips in Frozen Abdomen Management: Application of Coliseum Technique by Ioannis D. Kyriazanos, Dimitrios K. Manatakis, Nikolaos Stamos, Christos Stoidis

“…Relatively recently the concept of “intentional open abdomen” was described and both clinical entities share common pathophysiological and clinical pathways (“postoperative open abdominal wall”). …”
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Tea and depression by Klaus W. Lange, Yukiko Nakamura, Katharina M. Lange, Hui Zhao

“…Potent pharmacological effects on circumscribed neurobiological systems may be produced not by individual tea components but rather by the synergistic action of various compounds on multiple pathophysiological mechanisms involved in depression. While epidemiological studies have generally demonstrated beneficial effects of tea consumption on mood and depressive symptoms, cross-sectional studies are unable to prove a cause-effect relationship. …”
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The role of the interplay between macrophage glycolytic reprogramming and NLRP3 inflammasome activation in acute lung injury/acute respiratory distress syndrome by Lan Luo, Xiaoli Zhuang, Lin Fu, Ziyuan Dong, Shuyuan Yi, Kan Wang, Yu Jiang, Ju Zhao, Xiaofang Yang, Feilong Hei

“…Understanding their complex pathophysiological mechanisms is crucial for developing new preventive and therapeutic strategies. …”
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Kimura disease: A rare cause of cervical lymphadenopathy and a diagnostic challenge by Virendra Kumar Goyal, Jagdish Vishnoi, Ruhi Dak, Shokat Ali Bohra, Gunjan Sharma

“…An allergic reaction and an alteration of the immune system remains one of the pathophysiological bases. Persistent antigenic stimulation following arthropod bites and parasitic or candida infection are also suspected. …”
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Parathyroid carcinoma and pheochromocytoma in a patient with neurofibromatosis type 1: a rare association by Jardelina Brena Rocha Leite, Nicole Ramalho De Freitas, Rafaella Nelice de Holanda Cardoso, Erik Trovão Diniz, Gabriel Rodrigues de Assis Ferreira, Fernão Henrique Costa e Alvim, Camila Ribeiro Coutinho Madruga, Ana Carolina Thé Garrido, Luciano Albuquerque, Patricia Sampaio Gadelha, Ruy Lyra, Lucio Vilar

“…Further investigation into the underlying mechanisms linking these conditions is warranted to elucidate their pathophysiological interplay and inform optimal therapeutic strategies for affected individuals. …”
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Interaction of Bradykinin and B2 Bradykinin Receptor Antagonists with Colloidal Au Surface Explored by Surface-Enhanced Raman Scattering by Dominika Skołuba, Dariusz Sobolewski, Adam Prahl, Edyta Proniewicz

“…Bradykinin (BK), an endogenous peptide hormone, which is involved in a number of physiological and pathophysiological processes, and the potent B2 bradykinin receptor antagonists, [D-Arg0,Hyp3,Thi5,8,L-Pip7]BK, Aaa[D-Arg0,Hyp3,Thi5,8,L-Pip7]BK, [D-Arg0,Hyp3,Thi5,D-Phe7,L-Pip8]BK, and Aaa[D-Arg0,Hyp3,Thi5,D-Phe7,L-Pip8]BK, were deposited onto colloidal Au particles of 20 nm size. …”
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Urologic Characteristics and Sexual Behaviors Associated with Prostate Cancer in an African-Caribbean Population in Barbados, West Indies by Anselm J. M. Hennis, Suh-Yuh Wu, Barbara Nemesure, M. Cristina Leske

“…The contribution of sexual behaviors to the development and the outcomes of PC is likely due to multiple mechanisms, and further study will be necessary to elucidate the underlying pathophysiologic mechanisms in this and similar populations.…”
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Steatotic liver disease diagnosed in a 24-year-old woman with Rett syndrome: a case report by Larissa Albino, Adil Adatia, Aducio Thiesen, Brendan Halloran, Victor Dong, Carlos Moctezuma-Velázquez

“…This case supports the hypothesis that MECP2 mutations in RTT disrupt lipid metabolism through a unique pathophysiologic mechanism, increasing the risk of DLD and SLD independently of traditional metabolic syndrome factors. …”
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Targeting the B-Cell Pathway in Lupus Nephritis: Current Evidence and Future Perspectives by Panagiotis Pateinakis, Athina Pyrpasopoulou

“…This review aims to expand on the proposed pathophysiologic mechanisms implicating the B-cell pathway in the pathogenesis of lupus nephritis and summarize current knowledge obtained from clinical trials introducing these biologics in its treatment. …”
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Liver Protective Effect of Fenofibrate in NASH/NAFLD Animal Models by Ali Mahmoudi, Seyed Adel Moallem, Thomas P. Johnston, Amirhossein Sahebkar

“…To better elucidate the pathophysiological processes underlying NAFLD, as well as to test therapeutic agents/interventions, experimental animal models have been extensively used. …”
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Osmotic myelinolysis: literature review and case report by G. Rutkauskaitė, A. Klimašauskienė

“…There are several pathophysiologic mechanisms that explain the development of osmotic myelinolysis. …”
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The generation and evaluation of TKO/hCD55/hTM/hEPCR gene-modified pigs for clinical organ xenotransplantation by Guoli Huai, Yong Wang, Jiaxiang Du, Zhenhui Cheng, Yuxuan Xie, Jia Zhou, Hongmei Tang, Yanyan Jiang, Xiangyang Xing, Shaoping Deng, Dengke Pan, Dengke Pan, Dengke Pan

“…Blood from gene-edited pigs was used for pathophysiological analysis.ResultsComplete knockout of GGTA1, CMAH, and B4GALNT2 was confirmed in 6GE pigs. …”
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Navigating the depths: A comprehensive narrative review on depression in people with epilepsy by Norah A. Alkhaldi

“…Our review rigorously explores the latest pathophysiological insights linking depression and epilepsy while critically evaluating contemporary treatment paradigms for individuals grappling with these comorbid conditions. …”
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