An Easy and Quick Risk-Stratified Early Forewarning Model for Septic Shock in the Intensive Care Unit: Development, Validation, and Interpretation Study by Guanghao Liu, Shixiang Zheng, Jun He, Zi-Mei Zhang, Ruoqiong Wu, Yingying Yu, Hao Fu, Li Han, Haibo Zhu, Yichang Xu, Huaguo Shao, Haidan Yan, Ting Chen, Xiaopei Shen

“…NS_HR patients, overlooked by the Sepsis-3 definition, may provide further insights into the pathophysiological processes of SS onset and help to complement its diagnosis and precise management. …”
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Chronic gastritis and functional dyspepsia: is there an exit out of the dead spot? (reflections, blown together by Rome criteria III) by A. A. Sheptulin

“…Combination of specified diagnoses is most justified, which allows to estimate severity of morphological changes of mucosa of the stomach, to establish basic pathophysiological mechanisms of development of dyspeptic complaints, to determine optimal management approach.Conclusion. …”
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Research Progress of Perioperative Anesthesia Management in Patients with Hypertrophic Cardiomyopathy by LIN Shuantong, SU Xiaojun, CAO Dequan

“…Hypertrophic cardiomyopathy, a genetic hereditary disease, is highly regarded in clinical practice due to its unique pathophysiological changes, course characteristics, and hemodynamic features. …”
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Pancreatitis with Electrocardiographic Changes Mimicking Acute Myocardial Infarction by Paul Khairy, Pierre Marsolais

“…A review of the literature and possible pathophysiological mechanisms of electrocardiographic changes in acute pancreatitis, such as metabolic abnormalities, hemodynamic instability, vasopressors, pericarditis, myocarditis, a cardiobiliary reflex, exacerbation of underlying cardiac pathology, coagulopathy and coronary vasospasm, are discussed.…”
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Postanoxic Burst Suppression Electroencephalogram in a Comatose Child Associated with Spontaneous Eyelid Opening by John R. Crawford

“…These electroencephalographic findings are important for intensive care physicians to recognize and may provide further insight into the pathophysiological mechanism of this rare phenomenon.…”
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Resistant Hypertension and Obstructive Sleep Apnea: The Sparring Partners by Costas Thomopoulos, Helena Michalopoulou, Alexandros Kasiakogias, Anna Kefala, Thomas Makris

“…Enhanced target organ damage and cardiovascular morbidity represent common issues observed in both resistant hypertension and obstructive sleep apnea. Common pathophysiological features and risk factors justify their coexistence, especially in individuals with increased upper-body adiposity. …”
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Recent Advances in the Recognition and Management of Eosinophilic Esophagitis by Gregory Eustace, Xianyong Gui, Marietta Iacucci

“…The incidence and recognition of eosinophilic esophagitis is increasing. Pathophysiological understanding of eosinophilic esophagitis is improving and an immunological reaction to ingested food is likely to play a significant role. …”
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A Review of Current Management of Vitreomacular Traction and Macular Hole by Alfredo García-Layana, José García-Arumí, José M. Ruiz-Moreno, Lluís Arias-Barquet, Francisco Cabrera-López, Marta S. Figueroa

“…The paper presents a review of the sequence of events of posterior vitreous detachment (PVD), vitreomacular adhesion (VMA), vitreomacular traction (VMT), and macular hole (MH) from their pathophysiological aspects, clinical features, diagnostic implications, and current management strategies. …”
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Akinetopsia: a systematic review on visual motion blindness by Johanna L. Browne, Lydia Krabbendam, Jan Dirk Blom, Jan Dirk Blom, Jan Dirk Blom

“…Of the clinical cases, 12% showed hemiakinetopsia, 50% continuous or progressive symptoms, and 52% a chronic course. Pathophysiologically, in right-handed individuals, the left area V5/MT was found to be particularly susceptible to acute interference, as evidenced by the experimental studies. …”
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Role of cardiac CT in the diagnostic evaluation and risk stratification of patients with myocardial infarction and non-obstructive coronary arteries (MINOCA): rationale and design... by Konstantinos Tsioufis, Haralambos Karvounis, George Giannakoulas, Theodoros Karamitsos, Ronny R Buechel, Konstantinos Kouskouras, Ioannis Vogiatzis, Konstantinos Toutouzas, Nathaniel R Smilowitz, Georgios P Rampidis, Polydoros Ν Kampaktsis, Athanasios Samaras, Georgios Benetos, Andreas Α Giannopoulos, Alexandros Kallifatidis, Antonios Samaras, Stavros Hadjimiltiades, Antonios Ziakas, Catherine Gebhard, Panagiotis Prassopoulos, Harmony Reynolds

“…Cardiac MR (CMR) and optical coherence tomography have been used to identify the underlying pathophysiological mechanism in MINOCA. The role of cardiac CT angiography (CCTA) in patients with MINOCA, however, has not been well studied so far. …”
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Update for diagnosis and treatment of syndrome after cardiac injury: a mini-review by Ruihui Lai, Tan Xu, Tan Xu

“…This review aims to provide a comprehensive explicit of the epidemiological characteristics, relevant pathophysiological mechanisms, diagnostic methods, and treatment strategies associated with PCIS, further fostering a deeper understanding and promoting advancements in the prevention and treatment of PCIS.…”
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Role and interactions of organelle stress in septic cardiomyopathy by Wei Wei, Zhang Jinbo, Zhang Zhaocai

“…The excessive inflammatory response, immune dysfunction, and dysregulation of homeostasis induced by sepsis can trigger abnormal stress responses in organelles such as endoplasmic reticulum, mitochondria, and Golgi apparatus, regulating the pathophysiological progression of SCM. This article focuses on organelle stress responses, analyzing their roles and mechanisms in SCM. …”
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The Functions of PPARs in Aging and Longevity by Adnan Erol

“…Peroxisome proliferator-activated receptors (PPARs) are key regulators in various age-associated pathophysiological processes related to energy metabolism and oxidative stress. …”
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Premonitory Urges and Sensorimotor Processing in Tourette Syndrome by Sangeerthana Rajagopal, Stefano Seri, Andrea Eugenio Cavanna

“…In the present article we present the results of a systematic literature review of the published studies addressing the pathophysiological mechanisms of premonitory urges. We identified some preliminary evidence for specific alterations in sensorimotor processing at both cortical and subcortical levels. …”
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TLR2 and TLR4 in the Brain Injury Caused by Cerebral Ischemia and Reperfusion by Ying Wang, Pengfei Ge, Yuhong Zhu

“…Brain injury caused by cerebral ischemia/reperfusion is a complicated pathophysiological course, in which inflammation is thought to play an important role. …”
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Discussion of functional dyspepsia issue in American gastroenterological week reports (Orlando, 2013) by A. A. Sheptulin

“…Treatment of FD includes application first of all of proton pump inhibitors, prokinetics, antidepressants and selective serotonin reuptake inhibitors.Conclusion. Pathophysiological and clinical aspects of FD require further studying.…”
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Limb Body Wall Complex: First Trimester Ultrasonographic Diagnosis of a Case with Exencephaly and Megacystis by Mert Turğal, Aslıhan Yazıcıoğlu, Özgür Özyüncü, M. Sinan Beksaç

“…Despite the anomaly arises from an error occuring during the embryonic folding, the exact pathophysiological mechanisms are poorly understood. The clinical picture is characterized by thoracoabdominoschisis, eventration of the internal organs, limb reduction defects and sometimes craniofacial abnormalities. …”
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CAR-T therapy toxicities: the importance of macrophages in their development and possible targets for their management by Joseph Norton, Patrick Stiff

“…Herein, we review the immune mediated adverse events related to CAR therapy, including their pathophysiologies, and current therapies. In particular, we discuss the emerging role of the MPS in both the toxicity and efficacy of CAR-T therapy, and possible avenues for the modulation of the MPS to optimize efficacy while minimizing toxicity.…”
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Obesity Hypertension: The Regulatory Role of Leptin by Shilpa Kshatriya, Kan Liu, Ali Salah, Tamas Szombathy, Ronald H. Freeman, Garry P. Reams, Robert M. Spear, Daniel Villarreal

“…However, in abnormal situations characterized by chronic hyperleptinemia such as obesity, it may function pathophysiologically for the development of hypertension and possibly also for direct renal, vascular, and cardiac damage.…”
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Neurobiology of Vascular Dementia by Ana-Maria Enciu, Stefan N. Constantinescu, Laurenţiu M. Popescu, Dafin F. Mureşanu, Bogdan O. Popescu

“…Vascular dementia is, in its current conceptual form, a distinct type of dementia with a spectrum of specific clinical and pathophysiological features. However, in a very large majority of cases, these alterations occur in an already aged brain, characterized by a milieu of cellular and molecular events common for different neurodegenerative diseases. …”
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