Parkinson’s Disease: New Insights into Pathophysiology and Rehabilitative Approaches by Vincenza Frisardi, Andrea Santamato, Binith Cheeran

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A Review of the Pathophysiology and Novel Treatments for Erectile Dysfunction by George F. Lasker, Jason H. Maley, Philip J. Kadowitz

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Interferon-gamma rescues dendritic cell calcineurin-dependent responses to Aspergillus fumigatus via Stat3 to Stat1 switching by Amit Adlakha, Thomas J. Williams, Xinxin Shou, Anna K. Reed, Boris Lenhard, Darius Armstrong-James

Subjects: “…Pathophysiology…”
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Adrenal Disorders and the Paediatric Brain: Pathophysiological Considerations and Clinical Implications by Vincenzo Salpietro, Agata Polizzi, Gabriella Di Rosa, Anna Claudia Romeo, Valeria Dipasquale, Paolo Morabito, Valeria Chirico, Teresa Arrigo, Martino Ruggieri

“…Based on literature review and on personal case-studies and case-series we focused on the pathophysiological and clinical implications of glucocorticoid-related, mineralcorticoid-related, and catecholamine-related paediatric nervous system involvement. …”
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Impact of Thrombopoietin Receptor Agonists on Pathophysiology of Pediatric Immune Thrombocytopenia by Paschalis Evangelidis, Konstantinos Tragiannidis, Eleni Gavriilaki, Athanasios Tragiannidis

“…Immune thrombocytopenia (ITP) in pediatric patients is a common cause of isolated thrombocytopenia. Various pathophysiological mechanisms are implicated in ITP pathogenesis, including the production of autoantibodies against components of platelets (PLTs) by B-cells, the activation of the complement system, phagocytosis by macrophages mediated by Fcγ receptors, the dysregulation of T cells, and reduced bone marrow megakaryopoiesis. …”
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Cardiovascular Effects of Diabetes Mellitus: A Review of Pathophysiology and Management by Omar Elsaka

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Increased Choroidal Thickness in Keratoconus Patients: Perspectives in the Disease Pathophysiology by João Pinheiro-Costa, João Viana Pinto, Sara Perestrelo, João Nuno Beato, Luís Torrão, Elisete Brandão, Ângela Carneiro, Maria Dulce Madeira, Fernando Falcão-Reis

“…Keratoconus patients seem to have a thicker choroid than healthy individuals. The exact pathophysiological mechanism resulting in a thicker choroid in KC patients is not known, but it could possibly be associated with inflammatory choroidal mechanisms.…”
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Recent Advances in Methamphetamine Neurotoxicity Mechanisms and Its Molecular Pathophysiology by Shaobin Yu, Ling Zhu, Qiang Shen, Xue Bai, Xuhui Di

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Pathophysiologic Mechanisms of Cardiovascular Disease in Obstructive Sleep Apnea Syndrome by Carlos Zamarrón, Luis Valdés Cuadrado, Rodolfo Álvarez-Sala

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Hepatic Disorders and COVID-19: From Pathophysiology to Treatment Strategy by Parisa Shiri Aghbash, Hamed Ebrahimzadeh Leylabadlo, Hamidreza Fathi, Mohaddeseh Bahmani, Rojin Chegini, Hossein Bannazadeh Baghi

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Fatigue in chronic liver disease patients: prevalence, pathophysiology, and management by Artur Kośnik, Maciej Wójcicki

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“Lung-on-a-chip” as an instrument for studying the pathophysiology of human respiration by Oksana A. Zhukova, Iuliia V. Ozerskaya, Dmitry V. Basmanov, Vsevolod Yu. Stolyarov, Vladimir G. Bogush, Vladimir V. Kolesov, Kirill A. Zykov, Gaukhar M. Yusubalieva, Vladimir P. Baklaushev

“…“Lung-on-a-chip” (LoC) is a microfluidic device, imitating the gas-fluid interface of the pulmonary alveole in the human lung and intended for pathophysiological, pharmacological and molecular-biological studies of the air-blood barrier in vitro. …”
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IMMUNE THROMBOTIC THROMBOCYTOPENIC PURPURA: PATHOPHYSIOLOGY, DIAGNOSIS AND OPEN ISSUES. by Silvia Maria Trisolini, Alessandro Laganà, Saveria Capria

“… Immune thrombotic thrombocytopenic purpura (iTTP) is a life-threatening thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, thrombocytopenia, and ischemic end organ injury due to microvascular platelet-rich thrombi. iTTP pathophysiology is based on a severe ADAMTS13 deficiency, the specific von Willebrand factor (vWF)-cleaving protease, due to anti-ADAMTS13 autoantibodies. …”
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Serotonin circuits act cooperatively with pathophysiology of opioid use disorder by Arakawa Hiroyuki, Ozawa Akihiko

“…We interrogate the potential neural roles of 5-HT in OUD-related symptoms including 5-HT toxicity and pathophysiology and discuss potential availability of 5-HT-related agents as a neuromodulatory therapeutic interacting with opioid mediated neural mechanisms and the OUD-related symptoms.…”
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Pathophysiology and Treatment of Psoriasis: From Clinical Practice to Basic Research by Yujie Gao, Tianqi Xu, Yu Wang, Yanjinhui Hu, Shaoping Yin, Zhiguo Qin, Hua Yu

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Acute therapeutic effects and pathophysiology of eosinophilic granulomatosis with polyangiitis neuropathy by Fumitaka Shimizu, Mariko Oishi, Toshihiko Maeda, Yukio Takeshita, Hideaki Nishihara, Ryota Sato, Takashi Kanda, Masayuki Nakamori, Michiaki Koga, Miwako Fujisawa, Yuki Mizumoto, Nanami Yamanaka, Takashi Nawata, Tatsuya Okafuji, Susumu Fujikawa, Kinya Matsuo, Joe Nemoto, Masaya Honda

“…Objective This study investigated the effects of early treatment and pathophysiology on eosinophilic granulomatosis with polyangiitis neuropathy (EGPA-N).Methods Twenty-six consecutive patients with EGPA-N were diagnosed and treated within a day of admission and underwent clinical analysis. …”
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A Pathophysiological Insight into Sepsis and Its Correlation with Postmortem Diagnosis by C. Pomara, I. Riezzo, S. Bello, D. De Carlo, M. Neri, E. Turillazzi

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Diabetes mellitus: The pathophysiology as a canvas for management elucidation and strategies by Franklyn Nonso Iheagwam, Olawumi Toyin Iheagwam

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Diagnostic and Pathophysiological Impact of Myocardial MIBG Scintigraphy in Parkinson's Disease by Jörg Spiegel

“…Numerous studies address the pathophysiological impact of myocardial MIBG scintigraphy: the myocardial MIBG uptake correlates with the clinical phenotype of PD; the background of this phenomenon is unclear. …”
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Novel Management for Severe Odontogenic Maxillary Sinusitis Based on Pathophysiology by Yoshio Ohyama, Masaru Ogawa, Satoshi Yokoo

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