Relationship between Experimental Diet in Rats and Nonalcoholic Hepatic Disease: Review of Literature by Ayane A. Rodrigues, Raíssa S. B. Andrade, Daniel F. P. Vasconcelos

“…Background. The pathophysiology of nonalcoholic fatty liver disease (NAFLD) is related to unhealthy lifestyles that combine sedentary lifestyle, hypercaloric diets, excessive saturated fats, refined carbohydrates, and high intake of fructose as a food additive to various processed products. …”
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Incidental imaging detection of Kartagener syndrome in a female: A case report by Natasha Dhakal, MBBS, Prajwal Dahal, MD

“…Kartagener syndrome is a rare ciliopathic genetic disorder characterized by a triad of chronic sinusitis, situs inversus, and bronchiectasis. The underlying pathophysiology involves reduced ciliary motility due to defects in ciliary structure and function within the respiratory tract and fallopian tubes. …”
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Leukocyte Adhesion Molecules in Diabetic Retinopathy by Kousuke Noda, Shintaro Nakao, Susumu Ishida, Tatsuro Ishibashi

“…The mechanisms underlying the development of DR are not fully understood; however, extensive studies have recently implicated chronic, low-grade inflammation in the pathophysiology of DR. During inflammation leukocytes undergo sequential adhesive interactions with endothelial cells to migrate into the inflamed tissues, a process known as the “leukocyte recruitment cascade” which is orchestrated by precise adhesion molecule expression on the cell surface of leukocytes and the endothelium. …”
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Acute respiratory failure induced by belly dancer’s syndrome: A glance to a rare case report by Ruth Elizabeth Abraham, Gan Lay Min, Ahmad Luqman Bin Md Pauzi, Noor Hafizah Abdul Salim, Iskasymar Ismail

“…Currently, there is no definite pathophysiology that clearly explains this condition. …”
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Vasculitic Tibial Mononeuropathy Associated with Inherited Immune Dysregulation: A Review of Tibial Mononeuropathies with Electrodiagnostic Considerations by James Liu, Yue Ding, Sandra Camelo-Piragua, James Richardson

“…Furthermore, this case highlights the critical role of the electromyographer and ability to maximize the impact on patient care through a solid foundation in anatomy, pathophysiology, and electrodiagnosis blended with clinical acumen.…”
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Genetic Associations in Acquired Immune-Mediated Bone Marrow Failure Syndromes: Insights in Aplastic Anemia and Chronic Idiopathic Neutropenia by Irene Mavroudi, Helen A. Papadaki

“…However, in immune-mediated bone marrow failure syndromes, such as acquired aplastic anemia and chronic idiopathic neutropenia, in which the pathophysiology results from a myelosuppressive bone marrow microenvironment mainly due to the presence of activated T lymphocytes, leading to the accelerated apoptotic death of the hematopoietic stem and progenitor cells, such genetic associations have been very limited. …”
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Concurrent Polycythemia of Undetermined Etiology and Smouldering Plasma Cell Myeloma by Roula Katerji, Chad A. Hudson

“…This case highlights that while being unusual, polycythemia and plasma cell myeloma can occur concurrently, and, in this report, we discuss both entities and potential mechanisms of the pathophysiology of the concurrent presentation.…”
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Sister Mary Joseph's Nodule as a First Manifestation of Primary Peritoneal Cancer by C. Iavazzo, K. Madhuri, S. Essapen, N. Akrivos, A. Tailor, S. Butler-Manuel

“…Through a literature search, we also discuss the pathophysiology, diagnostic approach, management, and prognosis of such a condition.…”
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The Specific Dermatoses of Pregnancy by Paulina Polańska

“…While some pose minimal risk to the fetus, others, such as ICP and PG, are associated with significant complications, including preterm birth and stillbirth. The underlying pathophysiology remains incompletely understood, with hormonal, immunological, genetic, and environmental factors playing key roles. …”
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A Rare Case of Posttraumatic Bilateral BPPV Presentation by Sinisa Maslovara, Andro Kosec, Ivana Pajic Matic, Anamarija Sestak

“…With a good knowledge of the etiopathogenesis, pathophysiology and clinical forms of BPPV, we can, in most cases, make an accurate and precise diagnosis of the disease and carry out appropriate treatment.…”
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Association Study between BGLAP Gene HindIII Polymorphism and Type 2 Diabetes Mellitus Development in Ukrainian Population by Yaroslav D. Chumachenko, Viktoriia Yu. Harbuzova, Alexander V. Ataman

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Pouchitis unveiled: exploring clinical features, diagnosis, and cutting-edge treatments by Francesca Lusetti, Camilla Almeida Martins Helfenberger, Munique Kurtz de Mello, Natália Sousa Freitas Queiroz

“…Currently, there is still no consensus on the optimal management for CP, though recent progress in understanding the pathophysiology of pouchitis has paved the way for innovative therapeutic approaches, based on biological therapies and small molecules. …”
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Activated neutrophils: A next generation cellular immunotherapy by Ninad Kumbhojkar, Samir Mitragotri

“…Neutrophils, despite being the most populous immune cells in human blood circulation, are not considered a viable option for cellular therapies because of their short lifespan and poor understanding of their role in the pathophysiology of various diseases. In inflammatory conditions, neutrophils exhibit an activated phenotype. …”
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The Role of RSV Infection in Asthma Initiation and Progression: Findings in a Mouse Model by Junyan Han, Katsuyuki Takeda, Erwin W. Gelfand

“…To study these processes in ways which are not available in humans, animal models have been established and have provided valuable insight into the pathophysiology of RSV-induced disease. In this paper, we discuss experimental models of RSV infection in mice and highlight a new investigative approach in which mice are initially infected as neonates and then reinfected later in life. …”
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Assessment of Serum Adiponectin and Leptin in Chronic Periodontitis Over Healthy Individuals by Reghunathan S. Preethanath, Swaroop Chandy, Nubesh Khan Syed, Bugude Shiva Shankar, Pavithra Rangarajan Seshadri, R Narayane, P. K. Saraswathi Bai

“…Conclusion: The current investigation leads us to the conclusion that the pathophysiology of periodontitis is significantly influenced by serum levels of adiponectin and leptin.…”
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Inflammatory Signalling Associated with Brain Dead Organ Donation: From Brain Injury to Brain Stem Death and Posttransplant Ischaemia Reperfusion Injury by Ryan P. Watts, Ogilvie Thom, John F. Fraser

“…Brain death is associated with dramatic and serious pathophysiologic changes that adversely affect both the quantity and quality of organs available for transplant. …”
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Identification of Novel Mutations in Spatacsin and Apolipoprotein B Genes in a Patient with Spastic Paraplegia and Hypobetalipoproteinemia by Leema Reddy Peddareddygari, Raji P. Grewal

“…We report a patient with autosomal recessive (AR) HSP in whom laboratory investigations revealed hypobetalipoproteinemia raising the possibility of a shared pathophysiology of these clinical features. A lipid profile of his parents disclosed a normal maternal lipid profile. …”
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Zinc in the Monoaminergic Theory of Depression: Its Relationship to Neural Plasticity by Urszula Doboszewska, Piotr Wlaź, Gabriel Nowak, Maria Radziwoń-Zaleska, Ranji Cui, Katarzyna Młyniec

“…In this review we aim to discuss the role of zinc in the pathophysiology and treatment of depression with regard to the monoamine hypothesis of the disease. …”
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CLOCK Genes and Circadian Rhythmicity in Alzheimer Disease by J. Thome, A. N. Coogan, A. G. Woods, C. C. Darie, F. Häßler

“…Presently, more and more data are emerging demonstrating how alterations of the CLOCK gene system might contribute to the pathophysiology of AD and other forms of dementia. At the same time, the impact of neuropsychiatric medication on CLOCK gene expression is under investigation.…”
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Impact of MMP-9 Genetic Polymorphism and Concentration on the Development of Coronary Artery Disease in Ukrainian Population by Oksana S. Pogorielova, Viktoriia V. Korniienko, Yaroslav D. Chumachenko, Olha A. Obukhova, Igor Martsovenko, Viktoriia Yu. Harbuzova

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