The Enteric Nervous System in Inflammation and Pain: The Role of Proteinase-Activated Receptors by Nathalie Vergnolle

“…Drugs that interact with the ENS have recently raised considerable interest because of their capacity to regulate numerous aspects of the gut physiology and pathophysiology. The present article summarizes recent research on proteinases and proteinase-activated receptors (PARs) as signalling molecules in the ENS. …”
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Questions and Considerations on Anesthesia in the Elderly by Evangelina Dávila Cabo de Villa

“…Scientific advances have enhanced progresses in the understanding of diseases’ pathophysiology, thus enabling the performance of a higher number of surgical procedures. …”
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Severe Dilatation of Coronary Artery Ostium Complicating Sinus of Valsalva Aneurysm: Differential Diagnosis and Review of the Literature by Paul Bamford, Nicholas Collins

“…This represents an unusual manifestation of a sinus of Valsalva aneurysm. The underlying pathophysiology, differential diagnosis, role of surgical management, and outcomes are discussed.…”
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Influence of opioid peptides on human neutrophil apoptosis and activation in vitro by Zofia Sulowska, Ewa Majewska, Katarzyna Krawczyk, Magdalena Klink, Henryk Tchórzewski

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Manic Pseudo-Delirium–Two Case Reports by Gerard Hutchinson, Anthony David

“…Possible explanations for MP-D are put forward for their heuristic value in the hope that further research will improve understanding of the pathophysiology of both mania and delirium.…”
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Liver Cell Death: Update on Apoptosis by Marc Bilodeau

“…The significance of apoptosis to the pathophysiology of liver disease is discussed.…”
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The Correlation of Hemostatic Parameters with the Development of Early Sepsis-Associated Encephalopathy. A Retrospective Observational Study by Scarlatescu Florin, Scarlatescu Ecaterina, Tomescu Dana Rodica, Bartos Daniela

“…Sepsis-associated encephalopathy (SAE) is one of the most common complications seen both in early and late stages of sepsis, with a wide spectrum of clinical manifestations ranging from mild neurological dysfunction to delirium and coma. The pathophysiology of SAE is still not completely understood, and the diagnosis can be challenging especially in early stages of sepsis and in patients with subtle symptoms.…”
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The Link between Allergic Rhinitis and Asthma: A Role for Antileukotrienes? by H Kim, J Bouchard, PM Renzix

“…Both are inflammatory disorders with a similar pathophysiology, and both share some treatment approaches. …”
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Inflammatory Response and Immune Regulation in Brain-Heart Interaction after Stroke by Lihua Zou, Ruquan Han

“…Systemic inflammatory response syndrome (SIRS) evoked by stroke may injure myocardial cells directly, in which the interplay between inflammatory response, oxidative stress, cardiac sympathetic/parasympathetic dysfunction, and splenic immunoregulation may be also the key pathophysiology factor. This review article summarizes the current understanding of inflammatory response and immune regulation in brain-heart interaction after stroke.…”
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The Importance of Monitoring Baseline and Regular Immunoglobulin Levels in Managing Secondary Hypogammaglobulinemia in Rheumatic Diseases: A Case Report and Systematic Review by Winnie Wan Yin Yeung

“…Herein, a case of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with recurrent cytomegalovirus (CMV) infections and SHG was described, followed by discussion of pathophysiology, clinical presentation, risk factors, and management of SHG, emphasizing the importance of baseline immunoglobulin level monitoring.…”
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Psudoxanthoma elasticum: An Unusual Case of Gastrointestinal Bleeding by Deborah J. Cook, Samih S. Salama, Robert J. Tuttle

“…An unusual case of gastrointestinal hemorrhage in a patient with PXE is described and the pathophysiology, clinical presentation and complications of this rare condition are reviewed.…”
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Sequential Analysis of Oxidative Stress Markers and Vitamin C Status in Acute Bacterial Osteomyelitis by Rade Grbic, Dijana J Miric, Bojana Kisic, Ljiljana Popovic, Vojkan Nestorovic, Aleksandar Vasic

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Persistent Down-Beating Torsional Positional Nystagmus: Posterior Semicircular Canal Light Cupula? by Akihide Ichimura, Koji Otsuka

“…This case provides novel insights into the light cupula pathophysiology.…”
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Cerebral Venous Thrombosis in the Setting of Malignancy: Case Report and Review of the Literature by Constantine N. Logothetis, Charles Pizanis

“…This case report and review of the literature addresses the epidemiology, pathophysiology, and medical treatment for malignancy-related CVT.…”
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Cigarette Smoking and Asthma: A Dangerous Mix by Catherine Lemiere, Louis-Philippe Boulet

“…However, most studies on the pathophysiology of asthma and its response to treatment only include nonsmokers. …”
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Mechanism of Lower Airway Hyperresponsiveness Induced by Allergic Rhinitis by Yiting Liu, Jichao Sha, Cuida Meng, Dongdong Zhu

“…In this paper, the effects of allergic rhinitis on the lower airways are studied in terms of epidemiology, anatomy, pathophysiology, nasal function loss, inflammation drainage, nasobronchial reflex, and whole-body circulatory flow to determine the mechanism involved and provide ideas for future diagnosis, treatment, and experiments.…”
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Nephrotic and Non-Nephrotic Focal Segmental Glomerulosclerosis: Clinical Characteristics, Etiology, and Columbia Classification by Gabriel Figueiredo, Luis Yu, Lectícia Barbosa Jorge, Viktoria Woronik, Cristiane Bitencourt Dias

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Digital sleep phenotype and wrist actigraphy in individuals at clinical high risk for psychosis and people with schizophrenia spectrum disorders: a systematic review and meta-analy... by Andrea Cipriani, Edoardo Giuseppe Ostinelli, John Torous, Paolo Brambilla, Philip McGuire, Dominic Oliver, Rosario Aronica, Charlotte Austin

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RIPK3-Mediated Necroptosis and Neutrophil Infiltration Are Associated with Poor Prognosis in Patients with Alcoholic Cirrhosis by Zhenzhen Zhang, Guomin Xie, Li Liang, Hui Liu, Jing Pan, Hao Cheng, Hua Wang, Aijuan Qu, Yan Wang

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Functional Constipation in Children: overview and new outcomes by Kamila Stępień, Maria Przygoda, Joanna Śnieżna, Gabriela Trestka, Sabina Adamczyk, Urszula Zelik, Jakub Dziewic, Wojciech Florczak, Wiktoria Domino, Jagienka Włodyka, Karol Dzwonnik

“…This review provides an overview of functional constipation in children, discussing its epidemiology, pathophysiology, clinical presentation, diagnostic approach, and management strategies. …”
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