The Long-Term Outcome Comparison of Different Time-Delayed Kallikrein Treatments in a Mouse Cerebral Ischemic Model by Yaohui Ni, Kefu Cai, Yujie Hu, Chuan-hui Wang, Yuanyuan Zhang, Hua Huang, Xing Su, Jin-hua Gu

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Serum Zinc Levels in Women with Polycystic Ovarian Syndrome are Lower as Compared to Those without Polycystic Ovarian Syndrome: A Cohort Study by Swati Dhar, Reena Yadav, Akash Tomar

“…It is unclear if serum zinc levels are correlated with polycystic ovary syndrome (PCOS) and its pathophysiology, although relation between diabetes and insulin resistance has been established. …”
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PHARC syndrome: an overview by Lusine Harutyunyan, Patrick Callaerts, Sascha Vermeer

“…Many aspects of the disease, such as the biochemistry and pathophysiology, are still not fully understood. We generated a clinical overview of all PHARC patients, including their mutations, described in literature so far. …”
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Epigenetic Mechanisms in Type-2 Diabetes Mellitus: A Narrative Review by Deenadhayalan Ashok, Monisha Prasad, Mohammad Fareed, Anis Ahmad Chaudhary

“…With an emphasise on the part that epigenetics plays in the pathophysiology of T2DM, the present study attempts to give a thorough overview of the mechanisms behind disease initiation, possible biomarkers, and the consequences for T2DM. …”
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Salivary proteomics and metaproteomics identifies distinct molecular and taxonomic signatures of type-2 diabetes by Diana Samodova, Evelina Stankevic, Mathilde Sonne Søndergaard, Naiyu Hu, Tarunveer S. Ahluwalia, Daniel R. Witte, Daniel Belstrøm, Anniek Frederike Lubberding, Pratik D. Jagtap, Torben Hansen, Atul S. Deshmukh

“…Abundance of peptides for bacterial genera such as Neisseria and Corynebacterium were altered showing biomarker potential, offering insights into disease pathophysiology and microbial applications for T2D management. …”
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Apolipoprotein C-I Levels Are Associated with the Urinary Protein/Urinary Creatinine Ratio in Pediatric Idiopathic Steroid-Sensitive Nephrotic Syndrome: A Case Control Study by Jun Odaka, Takahiro Kanai, Takane Ito, Takashi Saito, Jun Aoyagi, Hiroyuki Betsui, Takanori Yamagata

“…Our findings provide new insights into the pathophysiology of ISSNS.…”
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Disorders of Adipose Tissue and Lipodystrophies: Causes, Consequences, and Treatment Perspectives by Rosińska Kamila Rosińska, Ewelina Justyna Janicka, Julia Natalia Skibicka, Monika Niedźwiedzka, Mateusz Rosiński

“…OBJECTIVE: This study aims to analyze the pathophysiology, diagnosis, and treatment of lipodystrophies, particularly focusing on congenital, acquired, and HIV-associated forms. …”
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Advancements and Challenges in Immune Protection Strategies for Islet Transplantation by Xue Wang, Ziyuan Zeng, Dayan Li, Kai Wang, Wei Zhang, Yang Yu, Xi Wang

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The influence of the sinonasal microbiome on the development and management of rhinosinusitis by Miriam Lang, Dawid Bereza, Maria Kulak-Waśniewska, Igor Moreau, Paulina Polańska, Katarzyna Sokołowska, Barbara Woch

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Impact of Deep Brain Stimulation on Daily Routine Driving Practice in Patients with Parkinson’s Disease by Carsten Buhmann, Eik Vettorazzi, Christian Oehlwein, Fred Rikkers, Monika Poetter-Nerger, Alessandro Gulberti, Christian Gerloff, Christian K. Moll, Wolfgang Hamel

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Mechanistic studies on regulation of the activity of GPI-anchored serine protease testisin by WAN Jiahui, ZHOU Aiwu

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NR2F6 regulates stem cell hematopoiesis and myelopoiesis in mice by Johannes Woelk, Hamsa Narasimhan, Hamsa Narasimhan, Christa Pfeifhofer-Obermair, Barbara U. Schraml, Barbara U. Schraml, Natascha Hermann-Kleiter

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Changes in Locomotor Activity Observed During Acute Nicotine Withdrawal Can Be Attenuated by Ghrelin and GHRP-6 in Rats by Jázmin Ayman, András Buzás, Roberta Dochnal, Miklós Palotai, Miklós Jászberényi, Zsolt Bagosi

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Walker 256 Tumor Growth Suppression by Crotoxin Involves Formyl Peptide Receptors and Lipoxin A4 by Patrícia Brigatte, Odair Jorge Faiad, Roberta Cornélio Ferreira Nocelli, Richardt G. Landgraf, Mario Sergio Palma, Yara Cury, Rui Curi, Sandra Coccuzzo Sampaio

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Expression of SET Protein in the Ovaries of Patients with Polycystic Ovary Syndrome by Xu Boqun, Dai Xiaonan, Cui YuGui, Gao Lingling, Dai Xue, Chao Gao, Diao Feiyang, Liu Jiayin, Li Gao, Mei Li, Yuan Zhang, Xiang Ma

“…Combined with its localization in theca cells, SET may participate in regulating ovarian androgen biosynthesis and the pathophysiology of hyperandrogenism in PCOS.…”
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Clinical and Experimental Immunomodulation 2014 by Lenin Pavón, Oscar Bottasso, Hugo Besedosky, Roger Loria, Marco A. Velasco-Velázquez

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Cytokines as cellular communicators by R. Debets, H. F. J. Savelkoul

“…Cytokines and their receptors are involved in the pathophysiology of many diseases. Here we present a detailed review on cytokines, receptors and signalling routes, and show that one important lesson from cytokine biology is the complex and diverse regulation of cytokine activity. …”
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Ischemic Colitis in an Endurance Runner by Chase Grames, Cristóbal S. Berry-Cabán

“…This paper describes the pathophysiology, diagnostic approach, and management options.…”
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Recurrent Syncope in a Cancer Patient: A Case Report and Review of the Literature by Jyoti Sharma, Anne H. Dougherty

“…He was found to be suffering from neurocardiogenic reflex-mediated syncope secondary to mechanical compression of the carotid baroreceptors and glossopharyngeal nerve by the tumor. We discuss the pathophysiology of this case and the available treatment options.…”
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Update on Gastroesophageal Reflux and Respiratory Disease in Children by Susan R Orenstein

“…Dysfunctions of these protections likely underlie the pathophysiology of these disorders.…”
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