Neutrophilic Cell-Free Exudate Induces Antinociception Mediate by the Protein S100A9 by Rosana L. Pagano, Mario Mariano, Renata Giorgi

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Drug utilization study of antiparkinsonian medication in Romania during 25 years by Camelia Bucsa, Denisa Bruhs, Anamaria Apan, Elena Francu, Cristina Mogosan, Irina Iaru

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Investigating the potential immunomodulatory effects of commercial oral probiotic supplements on equine gastrointestinal tract barrier function by Agnieszka Żak-Bochenek, Paulina Żebrowska-Różańska, Joanna Bajzert, Łukasz Łaczmański, Bogumiła Szponar, Natalia Siwińska, Klaudia Gładysz, Katarzyna Sikorska, Anna Chełmońska-Soyta

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Chemokines by Richard Horuk

“…In this short review we examine the role of chemokines in host defence and in the pathophysiology of autoimmune diseases. We conclude by discussing various therapeutic approaches that target chemokine receptors and that could be beneficial in disease.…”
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Role Of Cgrp In Sensitization Of Dura Mater by K. Messlinger

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Editorial: Neuroplasticity in multiple sclerosis by Yavor Yalachkov, Soheila Karimi-Abdolrezaee, Eleonora Tavazzi

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Male Osteoporosis in the Elderly by Patrizia D’Amelio, Giovanni Carlo Isaia

“…This review comprises an overview of recent findings in pathophysiology, diagnosis, and treatment of male osteoporosis, with particular regard to the old population.…”
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Current Situation and Consideration about Rehabilitation of Spinal Cord Injury by Anren ZHANG

“…This article reviews the epidemiology, pathophysiology and present situation of treatment for SCI, and points out that conducting epidemiological investigation, establishing unified evaluation criterion of curative effect, arranging randomized controlled clinical trials and searching for safe and effective methods are important. …”
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Plasma Levels of Tumor Necrosis Factor-Alpha and Interleukin-6 in Obsessive Compulsive Disorder by N. Konuk, I. O. Tekın, U. Ozturk, L. Atik, N. Atasoy, S. Bektas, A. Erdogan

“…Recent research implicated place of an immune mechanism in the pathophysiology of obsessive-compulsive disorder (OCD). …”
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Selective Serotonin Reuptake Inhibitors and Associated Bleeding Risks: A Narrative and Clinical Review by Amber N. Edinoff, Keerthiga Raveendran, Marc A. Colon, Bennett H. Thomas, Katie A. Trettin, Grace W. Hunt, Adam M. Kaye, Elyse M. Cornett, Alan D. Kaye

“…A leading hypothesis of the pathophysiology of MDD is the monoamine deficiency hypothesis which suggests that depression is caused by depletion of serotonin, norepinephrine, or dopamine in the central nervous system. …”
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A Successfully Treated Case of Gastrointestinal Stromal Tumor Causing Severe Anemia and Localized Peritonitis Showing Angina Pectoris Resulting in Watershed Cerebral Infarction by Yoshihide Sehara, Yuka Hayashi, Kenichi Ohya, Naoki Kaneko, Mikio Sawada

“…Ischemic stroke following acute myocardial infarction is a rare but a serious complication. Because the pathophysiology of stroke is dynamic, it is often hard to identify the cause of stroke. …”
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Abdominal Obesity Is Associated with an Increased Risk of All-Cause Mortality in Males but Not in Females with HFpEF by Liyao Fu, Ying Zhou, Jiaxing Sun, Zhaowei Zhu, Shi Tai

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An Overview of In Vitro Models of Alcohol‐Related Hepatocellular Carcinoma by Anoïsia Courtois, Sophie Gérard, Damien Esparteiro, Eric Nguyen‐Khac, Ingrid Marcq, Grégory Fouquet

“…However, the impact of alcohol consumption on HCC pathophysiology and the associated mechanisms remains unclear. …”
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Blood Transcriptional Signatures for Disease Progression in a Rat Model of Osteoarthritis by Michał Korostyński, Natalia Małek, Marcin Piechota, Katarzyna Starowicz

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Whole Blood Metabolomic Profiling of Mice with Tacrolimus-Induced Chronic Nephrotoxicity: NAD⁺ Depletion with Salvage Pathway Impairment by Sho Nishida, Tamaki Ishima, Daiki Iwami, Ryozo Nagai, Kenichi Aizawa

“…Tacrolimus (TAC)-induced chronic nephrotoxicity (TAC nephrotoxicity) is a serious issue for long-term graft survival in kidney transplantation. However, the pathophysiology of TAC nephrotoxicity remains unclear. …”
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Proton magnetic resonance spectroscopy-based evaluation of metabolic abnormalities in the right dorsolateral prefrontal cortex and caudate nucleus in treatment-naïve patients with... by Gagan Hans, Uma Sharma, Novy Gupte, Ragul Ganesh, Vaibhav Patil, Pratap Sharan

“…Background: Obsessive-compulsive disorder (OCD) is a common psychiatric disorder whose underlying pathophysiology is insufficiently understood. The pathophysiology of OCD may be related to abnormalities in the biochemistry of neurotransmitters. …”
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Panduratin A Inhibits TNF Alpha-Stimulated Endothelial Cell Activation Through Suppressing the NF-κB Pathway by Kriangkrai Kiatsoonthon, Nitchakarn Phimthong, Saranyapin Potikanond, Nitwara Wikan, Wutigri Nimlamool

“…Our study suggests that PA may possibly be effective in blocking the pathophysiology of atherosclerosis.…”
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Deciphering Platelet Kinetics in Diagnostic and Prognostic Evaluation of Hepatocellular Carcinoma by Bibek Aryal, Munekazu Yamakuchi, Toshiaki Shimizu, Jun Kadono, Akira Furoi, Kentaro Gejima, Teruo Komokata, Teruto Hashiguchi, Yutaka Imoto

“…Liver pathophysiology can, directly and indirectly, impose morphological or biochemical abnormalities of the platelets. …”
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Disruption of the Suprachiasmatic Nucleus Blunts a Time of Day-Dependent Variation in Systemic Anaphylactic Reaction in Mice by Yuki Nakamura, Kayoko Ishimaru, Yu Tahara, Shigenobu Shibata, Atsuhito Nakao

“…Increased prevalence of anaphylaxis in industrialized countries requires urgent needs for better understanding of anaphylaxis. However, the pathophysiology of the disease is not fully understood. …”
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The Anti-Inflammatory Effect of Callicarpa nudiflora Extract on H. Pylori-Infected GES-1 Cells through the Inhibition of ROS/NLRP3/Caspase-1/IL-1β Signaling Axis by Lili Li, Bo Bao, Xingxing Chai, Xiaoyu Chen, Xiaohua Su, Shixiu Feng, Xiaohui Zhu

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