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The diagnosis of DIC: a current overview
Published 2025-01-01“…First, it relies on clinical manifestations and laboratory tests, which cannot reflect pathophysiology. Second, the clinical manifestations were not sensitive or specific. …”
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PRMT5-Mediated ALKBH5 Methylation Promotes Colorectal Cancer Immune Evasion via Increasing CD276 Expression
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Androgenetic Alopecia: A Review
Published 2024-04-01“…This study reviewed the current knowledge on the epidemiology, pathophysiology, clinical presentations, diagnosis, treatment, quality-of-life assessment and recent trends in androgenetic alopecia (AGA). …”
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349
Stem Cells as In Vitro Model of Parkinson's Disease
Published 2012-01-01“…We discuss how iPSCs are being exploited to illuminate disease pathophysiology, identify novel drug targets, and enhance the probability of clinical success of new drugs.…”
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350
The Role of Inflammation in the Pathogenesis of Preeclampsia
Published 2020-01-01“…Detailed understanding of pathophysiology of inflammatory process in PE can largely contribute to new, targeted anti-inflammatory therapies that may improve perinatal outcomes in PE patients.…”
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351
Concurrent Stenoocclusive Disease of Intracranial and Extracranial Arteries in a Patient with Polycythemia Vera
Published 2012-01-01“…There are rarely any additional extracranial stenoses occurring concurrently with moyamoya. The pathophysiology of moyamoya remains obscure, but hematologic disorders, notably sickle-cell anemia, have been associated in some cases. …”
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Phospholipid derived mediators and glomerulonephritis
Published 1993-01-01“…The contributions made by the various eicosanoids, PAF, the HETES and the lipoxins to the pathophysiology of glomerulonephritis is reviewed. A case can be made for clinical trials of PAF, leukotriene and thromboxane antagonists. …”
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Diabetes Is Associated with Increased Autoreactivity of Mannan-Binding Lectin
Published 2017-01-01“…These findings support the hypothesis of a significant role of MBL and the complement system in the pathophysiology of diabetic nephropathy.…”
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SHOX Duplication and Tall Stature in a Patient with Xq Deletion and Vascular Disease
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Integrated gene expression and alternative splicing analysis in human and mouse models of Rett syndrome
Published 2025-01-01“…Our extensive bioinformatics study indicates, for the first time, a significant dysregulation of AS in human RTT datasets, suggesting the crucial contribution of altered RNA processing to the pathophysiology of RTT.…”
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Vascular injury in glomerulopathies: the role of the endothelium
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Cryptosporidiosis in a Zoonotic Gastrointestinal Disorder Perspective
Published 2024-01-01“…Therefore, with the objective of providing an in-depth analysis of Cryptosporidiosis in immunocompromised patients, this review presents a comprehensive understating of the prevalence, risk factors, pathophysiology of Cryptosporidium infection, clinical presentation in the immunocompromised, the immune response of the host, diagnostic methods performed in laboratory settings, possible treatments, and prevention methods, which can be used for further studies. …”
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