The endocytic adaptor AP-2 maintains Purkinje cell function by balancing cerebellar parallel and climbing fiber synapses by Marianna Tolve, Janine Tutas, Ebru Özer-Yildiz, Ines Klein, Anne Petzold, Veronika J. Fritz, Melina Overhoff, Quinn Silverman, Ellie Koletsou, Filip Liebsch, Guenter Schwarz, Tatiana Korotkova, Silvana Valtcheva, Graziana Gatto, Natalia L. Kononenko

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Impact of elexacaftor/tezacaftor/ivacaftor (ETI) on the prescription refill rate (PRR) for inhaled medications in people with CF: an Italian multicenter analysis by Andrea Gramegna, Giuseppe Cimino, Marco Cipolli, Giovanna Gandini, Maria Adelaide Calderazzo, Angelica Profiti, Federica Piedepalumbo, Francesco Blasi

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Meningococcal B Vaccination (4CMenB) in Infants and Toddlers by Susanna Esposito, Claudia Tagliabue, Samantha Bosis

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Thiazolidinedione-Induced Fluid Retention: Recent Insights into the Molecular Mechanisms by Jerzy Bełtowski, Jolanta Rachańczyk, Mirosław Włodarczyk

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Use of the Triptans by Marek J Gawel

“…In the past 10 years, there have been great advances in the understanding of the pathophysiology of the migraine. This has been due in part to the realization that the migraine attack can be blocked by activating the serotonin receptor, namely the 5-hydroxytryptamine/1D receptor. …”
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Editorial: Novel treatments for cardiovascular diseases by targeting inflammation, oxidative stress, and cell death by Dong Fan, Li Wang, Abhijit Chakraborty, Cheng-Lin Zhang, Feng Hua Yang

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Challenges and considerations of genetic testing in von Willebrand disease by Omid Seidizadeh, Luciano Baronciani, Flora Peyvandi

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Secretory leukocyte protease inhibitor in punch biopsies from human colonic mucosa by Max Nyström, Ulla Peterson Westin, Carina Linder, Kjell Ohlsson

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Novel Therapeutic Approaches to the Treatment of Chronic Abdominal Visceral Pain by Franca Patrizi, Steven D. Freedman, Alvaro Pascual-Leone, Felipe Fregni

“…This paper will present an overview of the pathophysiology and the available therapies for CAVP, focusing on the recent advances in the treatment of this pathology.…”
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Interleukin-1-Beta and Dyslipidemic Syndrome as Major Risk Factors for Thrombotic Complications in Type 2 Diabetes Mellitus by Oana Bădulescu, Codruţa Bădescu, Manuela Ciocoiu, Magda Bădescu

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Confusional State in HaNDL Syndrome: Case Report and Literature Review by Sarah Nelson

“…While HaNDL syndrome has been a described entity since the 1980s, its pathophysiology has yet to be clearly defined.…”
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How a gene fuels ear infections by Sedigheh Delmaghani, Aziz El-Amraoui

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Relationship between Postmenopausal Estrogen Deficiency and Aneurysmal Subarachnoid Hemorrhage by Sadaharu Tabuchi

“…Estrogen has important effects on vascular physiology and pathophysiology of cerebral aneurysm and SAH and, thus, potential therapeutic implications. …”
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IgE-mediated histamine release from nasal mucosa is inhibited by SLPI (secretory leukocyte protease inhibitor) to the level of spontaneous release by U. Westin, E. Lundberg, K. Ohlsson

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Intra-pancreatic release of bradykinin during the course experimental pancreatitis in rat by P. Jönsson, K. Ohlsson

“…Kallikrein/Kininogn activation is an important pathophysiological event in acute pancreatitis, leading to microcirculatory changes within the gland. …”
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Meconium aspiration syndrome: An overview of the literature by Hueng-Chuen Fan, Chuan-Mu Chen

“…Concepts regarding pathophysiology and management have undergone drastic changes over the last few decades. …”
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Dry Eye Post-Laser-Assisted In Situ Keratomileusis: Major Review and Latest Updates by Eyal Cohen, Oriel Spierer

“…This article reviews the latest studies published on LASIK-associated dry eye, including epidemiology, pathophysiology, risk factors, preoperative assessment, and management.…”
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A Review on Current Osteoporosis Research: With Special Focus on Disuse Bone Loss by Roy Yuen-chi Lau, Xia Guo

“…The objective of this paper is to examine the unique pathology and underlying pathophysiology of disuse osteoporosis.…”
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A case report of an early neonatal death accompanied by disseminated intravascular coagulation caused by severe acute respiratory syndrome Coronavirus-2 infection by Mitić Gorana P., Spasić Igor G., Panjković Milana D., Vučković Biljana A.

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The presence of elafin, SLPI, IL1-RA and STNFα RI in head and neck squamous cell carcinomas and their relation to the degree of tumour differentiation by U. Westin, M. Nyström, I. Ljungcrantz, B. Eriksson, K. Ohlsson

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