Haplotype Analysis of Candidate Genes Involved in Inflammation and Oxidative Stress and the Susceptibility to Preeclampsia by Aiping Chen, Huifang Zhao, Jingli Wang, Ru Zhang, Jingjing Liu, Xin Zhao, Congying Li, Xuewen Jia, Xueying Li, Yan Lin, Mingzhen Guo, Sai Li, Chao Liu, Yuan Li, Shiguo Liu

“…Unbalanced inflammatory reactions and oxidative stress are inseparably interconnected, and both may play crucial roles in the pathophysiological mechanisms of preeclampsia (PE). In the published previous studies, we have genotyped for SNPs that related to inflammation (rs2227485, rs153109, rs17855750, rs2027432, rs2275913, rs763780, rs4819554, and rs13015714) and oxidative stress (rs1695, rs4680, rs1800566, rs4807542, rs713041, rs7579, rs230813, rs1004467, rs3824755, and rs9932581) to investigate whether these polymorphisms were associated with susceptibility to PE in a Chinese Han population. …”
Get full text