Liver Imaging and Data System (LI-RADS) Version 2018 and Other Imaging Features in Intrahepatic Cholangiocarcinoma in Chinese Adults with vs. without Chronic Hepatitis B Viral Infe... by Ying-ying Liang, Shuo Shao, Sichi Kuang, Jingbiao Chen, Jing Zhou, Bingjun He, Linqi Zhang, Yao Zhang, Kathryn J. Fowler, Jin Wang

“…We retrospectively enrolled 89 patients with pathologically proven iCCA after multiphase imaging performed between 2004 and 2017 at a tertiary medical center in southern China. …”
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Characterization of adrenal glands on computed tomography with a 3D V-Net-based model by Yuanchong Chen, Yaofeng Zhang, Xiaodong Zhang, Xiaoying Wang

“…The other cohort, consisting of 959 patients with pathologically confirmed adrenal lesions (external validation dataset 1), was included for validation of the classification performance of this model. …”
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Mesothelial cell responses to acute appendicitis or small bowel obstruction reactive ascites: Insights into immunoregulation of abdominal adhesion. by Melissa A Hausburg, Kaysie L Banton, Christopher D Cassidy, Robert M Madayag, Carlos H Palacio, Jason S Williams, Raphael Bar-Or, Rebecca J Ryznar, David Bar-Or

“…., acute appendicitis (AA), causes formation of reactive ascitic fluid (rA) that activates peritoneum surface mesothelial cells (MCs) to form adhesions. Pathologic adhesions may arise if restoration of MC-regulated fibrinolysis and secretion of glycocalyx (GCX) are disrupted. …”
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Relationship between Blood Lipid Profiles and Risk of Lupus Nephritis in Children by Jiajia Liu, Wenqi Song, Dawei Cui

“…A total of 134 children with newly diagnosed SLE were divided into LN and non-LN groups according to pathological renal biopsy results. Clinical manifestations and blood lipid profiles were analyzed and compared between the two groups, and the relationships between blood lipid profiles and risk of LN were evaluated. …”
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Identifying Risk Factors Associated With False‐Negative Results in US‐Guided Percutaneous Transthoracic Needle Lung Biopsy of Subpleural Pulmonary Lesions by Jiawei Yi, Mengjun Shen, Junhui He, Runhe Xia, Xinyu Zhao, Yin Wang

“…Materials and Methods This ambispective cohort study included patients with subpleural pulmonary lesions who underwent US‐PTLB with benign pathological findings between April 2017 and June 2022 (retrospective cohort) and between July 2022 and October 2022 (prospective cohort). …”
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Relevance of superoxide dismutase type 1 to lipoid pneumonia: the first retrospective case-control study by Yinan Hu, Yanhong Ren, Yinzhen Han, Zhen Li, Weiqing Meng, Yuhui Qiang, Mengyuan Liu, Huaping Dai

“…LP is difficult to differentiate from other similar diseases without pathological evidence, such as upper respiratory tract infection (URTI), pneumonia, cryptogenic organizing pneumonia (COP), pulmonary alveolar proteinosis (PAP), lung mucinous adenocarcinoma and pulmonary edema. …”
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Comprehensive analysis of causal pathogens and determinants influencing black rot disease development in MD2 pineapples by Manori Kuruppu, Yasmeen Siddiqui, Hala Badr Khalil, Hala Badr Khalil

“…However, postharvest losses due to pathological diseases remain a challenge. Black rot, a major postharvest disease, causes significant economic losses in pineapples. …”
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Decreased Gray Matter Volume in the Frontal Cortex of Migraine Patients with Associated Functional Connectivity Alterations: A VBM and rs-FC Study by Zhijian Cao, Wenjing Yu, Zhengxiang Zhang, Maosheng Xu, Jiangnan Lin, Luping Zhang, Wenwen Song

“…However, the pathophysiology and imaging markers specific for migraine pathologies are not well understood. In this study, we combined both structural and functional images to explore the concurrence and process of migraines. …”
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Patients with symptoms of delayed gastric emptying have a high prevalence of oesophageal dysmotility, irrespective of scintigraphic evidence of gastroparesis by George Triadafilopoulos, John O Clarke, Linda Nguyen

“…There was no relationship between oesophageal symptoms and motor or pH abnormalities in either groups.Conclusions Irrespective of gastric emptying delay by scintigraphy, patients with symptoms suggestive of gastric neuromuscular dysfunction have a high prevalence of oesophageal motor disorder and pathological oesophageal acid exposure that may contribute to their symptoms and may require therapy. …”
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Cytoreductive Nephrectomy and Nephrectomy/Complete Metastasectomy for Metastatic Renal Cancer by Paul Russo, Mark Synder, Andrew Vickers, Varuni Kondagunta, Robert Motzer

“…Between July 1989 and September 2003, we queried our department's renal tumor database for patients undergoing cytoreductive nephrectomy alone or in conjunction with complete metastasectomy. Clinical and pathological factors analyzed included primary tumor size, stage and histological subtype, age, gender, Karnofsky Performance Status (KPS) prior to nephrectomy, number and location of metastatic sites, and the presence or absence of any systemic therapy. …”
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Heterogeneity of avian infectious bronchitis virus population by Ye. V. Ovchinnikova, L. O. Scherbakova, S. N. Kolosov, A. N. Andriyasova, N. G. Zinyakov, Z. B. Nikonova, A. A. Kozlov, P. B. Akshalova, D. A. Altunin, D. B. Andreychuk

“…The data obtained indicate that, despite the vaccination used, a genetically diverse population of the infectious bronchitis virus circulates in the poultry farm, while the infection may not manifest itself at an early age, but may affect the flock productivity in the future due to pathological changes in the reproductive organs of laying chickens.…”
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Antiedemic Effect of the Myosin Light Chain Kinase Inhibitor PIK7 in the Rat Model of Myocardial Ischemia Reperfusion Injury by Dmitry L. Sonin, Mikhail S. Medved, Asker Y. Khapchaev, Maria V. Sidorova, Marina E. Palkeeva, Olga A. Kazakova, Garry V. Papayan, Daniil A. Mochalov, Sarkis M. Minasyan, Ilya E. Anufriev, Daria V. Mukhametdinova, Natalia M. Paramonova, Ksenia M. Balabanova, Anastasia S. Lopatina, Ilia V. Aleksandrov, Natalya Yu. Semenova, Anna A. Kordyukova, Kirill V. Zaichenko, Vladimir P. Shirinsky, Michael M. Galagudza

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Defects at the Posttranscriptional Level Account for the Low TCRζ Chain Expression Detected in Gastric Cancer Independently of Caspase-3 Activity by Ana Aguinaga-Barrilero, Patricia Castro-Sánchez, Ignacio Juárez, Alberto Gutiérrez-Calvo, Noelia Rodríguez-Pérez, Adela Lopez, Remedios Gómez, José M. Martin-Villa

“…These results further place the defect responsible for the low TCRζ expression in cancer at the posttranscriptional level and suggests contrary to what has been proposed in other pathologies that elevated caspase-3 activity is not the causative agent.…”
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Students’ perspective on new teaching concepts for medical studies: case- and competency-based learning in radiology by Max Masthoff, Friedrich Pawelka, Gisela Zak, Bas de Leng, Dogus Darici, Philipp Schindler, Walter Heindel, Anne Helfen

“…Significant improvement was observed in perceived competency in modality selection and description and interpretation of common pathologies, with the strongest effect for CT and MRI data. …”
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Newly identified c-di-GMP pathway putative EAL domain gene STM0343 regulates stress resistance and virulence in Salmonella enterica serovar Typhimurium by Kaifeng Chen, Lili Li, Nanwei Wang, Zhouping Zhou, Peng Pan, Chenggang Xu, Dage Sun, Jiayi Li, Changzhi Dai, Dai Kuang, Ming Liao, Jianmin Zhang

“…In in vivo experiments, mice challenged with 269ΔSTM0343 experienced greater weight loss, and the bacterial loads in the spleen, liver, and intestines were elevated by fivefold, 30-fold, and 21-fold, respectively, accompanied by more severe pathological damage. Mechanistic studies revealed that the adhesion and invasion capacities of 269ΔSTM0343ΔCsgB decreased by 29.41% and 68.58%, respectively, compared to 269ΔSTM0343. …”
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The immunogenicity of PRV ΔgE/TK/UL49.5 three-gene-deleted vaccine in mice by Chenmeng Ding, Yawei Sun, Xianfeng Zhang, Mengmeng Shi, Han Yang, Xin Zhou, Shuangshuang Li, Yongtao Li, Xia Yang, Linyang Yu, Lu Chen

“…Immunized mice could induce high levels of serum neutralization antibodies and immune cytokines, including IFN-γ and IL-4, which could provide complete protection against virulent PRV challenge. No obvious pathological damage was observed in lung, brain and trigeminal ganglion of mice immunized with PRV ΔgE/TK/UL49.5, and the tissue viral load was the lowest. …”
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Comparative Analysis of Automated and Handheld Breast Ultrasound Findings for Small (≤1 cm) Breast Cancers Based on BI-RADS Category by Han Song Mun, Eun Young Ko, Boo-Kyung Han, Eun Sook Ko, Ji Soo Choi, Haejung Kim, Myoung Kyoung Kim, Jieun Kim

“…Lesion sizes were compared between US and pathological findings. Statistical analyses were performed using Bowker’s test of symmetry, a paired <i>t</i>-test, and a cumulative link mixed model. …”
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Germline variants of the genes involved in NF-kB activation are associated with the risk of COPD and lung cancer development by Baranasic Jurica, Niazi Yasmeen, Chattopadhyay Subhayan, Rumora Lada, Ćorak Lorna, Dugac Andrea Vukić, Jakopović Marko, Samaržija Miroslav, Försti Asta, Knežević Jelena

“…Although results presented in this study do not fully support our hypothesis, it is worth to mention that the identified genes/SNPs that were associated with either COPD or LC risk, all were involved in the activation of the NF-κB transcription factor which is closely related to the regulation of the inflammatory response, a condition associated with both pathologies.…”
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Molecular genetics of idiopathic pulmonary fibrosis by R. N. Mustafin

“…This is due to the fact that pathological activation of transposons leads to violation of the regulation of genes, in the epigenetic control of which microRNA originating from these transposons are involved (due to the complementarity of nucleotide sequences). …”
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Inhibitory Effect of Lactobacillus delbrueckii subsp. bulgaricus KSFY07 on Kappa-Carrageenan-Induced Thrombosis in Mice and the Regulation of Oxidative Damage by Pan Wang, Fang Tan, Jianfei Mu, Hongjiang Chen, Xin Zhao, Yanan Xu

“…LDSB-KSFY07 was also able to reduce malondialdehyde (MDA) levels and increase superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) levels in the serum and liver tissues of thrombotic mice. Pathological observations showed that LDSB-KSFY07 reduced liver tissue lesions and tail vein thrombosis. …”
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