Formalin Fixation as Tissue Preprocessing for Multimodal Optical Spectroscopy Using the Example of Human Brain Tumour Cross Sections by Mona Stefanakis, Anita Lorenz, Jörg W. Bartsch, Miriam C. Bassler, Alexandra Wagner, Marc Brecht, Axel Pagenstecher, Jens Schittenhelm, Barbara Boldrini, Sabrina Hakelberg, Susan Noell, Christopher Nimsky, Marcos Tatagiba, Rainer Ritz, Karsten Rebner, Edwin Ostertag

“…One emerging technique to assist pathologists in future tumour diagnostics is multimodal optical spectroscopy. …”
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Pathological and radiological assessment of benign breast lesions with BIRADS IVc/V subtypes. should we repeat the biopsy? by Wesam Rjoop, Anwar Rjoop, Alia Almohtaseb, Lama Bataineh, Zeina Nser Joubi, Maha Gharaibeh, Abdalrahman Al-Qwabah, Yousef Alasheh, Ismail Matalka

“…The study recommends a correlation between clinical and radiological findings and encourages multidisciplinary decision-making among radiologists, pathologists, and clinicians to determine if a repeat biopsy is warranted. …”
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An exploratory study on the differential diagnostic indicators between adult systemic EBV-positive T-cell lymphoproliferative disorders and angioimmunoblastic T-cell lymphoma with... by Xiaodan Zheng, Yuanyuan Zheng, Yanlin Zhang, Jianlan Xie, Xiaojing Teng, Kuo Bi, Lan Sun, Xiaowen Huang, Mulan Jin, Xiaoge Zhou

“…Abstract Background The differential diagnosis between adult systemic EBV-positive T-cell lymphoproliferative disorders (EBV+ T-LPD) and angioimmunoblastic T-cell lymphoma (AITL) with multiple EBV infections is difficult, and distinguishing between the two has become a diagnostic challenge for pathologists. Given that the clinical treatment plans are different, an accurate diagnosis is a prerequisite to ensure effective treatment, therefore, it is extremely necessary and meaningful to find effective pathological indicators for distinguishing between two diseases. …”
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A Novel, Patient-Specific Mathematical Pathology Approach for Assessment of Surgical Volume: Application to Ductal Carcinoma in situ of The Breast by Mary E. Edgerton, Yao-Li Chuang, Paul Macklin, Wei Yang, Elaine L. Bearer, Vittorio Cristini

“…By obtaining these ratios at the time of initial biopsy, pathologists can employ our model to predict the size of the tumor and thereby inform surgeons how much tissue to remove (surgical volume). …”
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Advancing the application of the analytical renal pathology system in allograft IgA nephropathy patients by Xumeng Liu, Huiwen Fang, Dongmei Liang, Qunjuan Lei, Jiaping Wang, Feng Xu, Shaoshan Liang, Dandan Liang, Fan Yang, Heng Li, Jianghua Chen, Yuan Ni, Guotong Xie, Caihong Zeng

“…Consistency between the ARPS and pathologists was assessed using intraclass correlation coefficients. …”
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Protocol for a randomised phase 3 trial evaluating the role of Finasteride in Active Surveillance for men with low and intermediate-risk prostate cancer: the FINESSE Study by Samuel Smith, Peter Sasieni, William Cross, Richard Bryant, Steven Kennish, James Catto, Rachel Hubbard, Simon Faulkner, Rohit Chahal, Mohantha Dooldeniya, Marcus Cumberbatch, Bernard North, Alastair D Lamb, Roseann Kealy, Selina Bhattrai

“…An external panel of experts blinded to allocation will review all AS cessation and progression events. Trial pathologist’s and radiologist’s, blinded to allocation, will review representative cases. …”
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The Financial Implications of Pancreatic Surgery: The Hospital Is the Big Winner, Not the Surgeon! by Nitzan Zohar, MD, Avinoam Nevler, MD, Sean P. Maher, Matthew C. Rosenthal, Florence Williams, Wilbur B. Bowne, MD, FACS, Charles J. Yeo, MD, FACS, Harish Lavu, MD, FACS

“…The differences between the professional fee charges and receipts per patient were also considerable for other health care professionals such as anesthesiologists ($4945 charges vs $1406 receipts [28%]) and pathologists ($3035 charges vs $680 receipts [22%]). …”
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Relapse-free survival is progressively shortened in a subset of Black patients with immune-mediated TTP treated in the rituximab era by Ayotola Fatola, Michael D. Evans, Jenna Brown, Elizabeth Davis, Andrew Johnson, Ana G. Antun, Andrew M. Farland, Ryan Woods, Ara Metjian, Yara A. Park, Gustaaf de Ridder, Briana Gibson, Raj S. Kasthuri, Darla K. Liles, Susan Eubanks, Frank Akwaa, Todd Clover, Lisa Baumann Kreuziger, J. Evan Sadler, Meera Sridharan, Ronald S. Go, Keith R. McCrae, Harsh Vardhan Upreti, Ming Y. Lim, Nicole K. Kocher, Radhika Gangaraju, X. Long Zheng, Jay S. Raval, Camila Masias, Spero R. Cataland, Marshall Mazepa, Shruti Chaturvedi

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Histopathologic Progression and Metastatic Relapse Outcomes in Small Cell Neuroendocrine Carcinomas of the Urinary Tract by Mohammad Jad Moussa, Georges C. Tabet, Arlene O. Siefker‐Radtke, Lianchun Xiao, Nathaniel R. Wilson, Jianjun Gao, Christopher J. Logothetis, Petros Grivas, Byron Lee, Amishi Y. Shah, Pavlos Msaouel, Roger Li, Leticia Campos Clemente, Jianping Zhao, Nizar M. Tannir, Ashish M. Kamat, Donna E. Hansel, Charles C. Guo, Matthew T. Campbell, Omar Alhalabi

“…Histopathologic review was conducted by independent pathologists. Relapse event was the time‐to‐event outcome, and relapse probabilities were estimated using a competing risk method with cumulative incidence functions (CIFs). …”
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Adenomas from individuals with pathogenic biallelic variants in the MUTYH and NTHL1 genes demonstrate base excision repair tumour mutational signature profiles similar to colorecta... by Romy Walker, Jihoon E. Joo, Khalid Mahmood, Mark Clendenning, Julia Como, Susan G. Preston, Sharelle Joseland, Bernard J. Pope, Ana B.D. Medeiros, Brenely V. Murillo, Nicholas Pachter, Kevin Sweet, Allan D. Spigelman, Alexandra Groves, Margaret Gleeson, Krzysztof Bernatowicz, Nicola Poplawski, Lesley Andrews, Emma Healey, Steven Gallinger, Robert C. Grant, Aung K. Win, John L. Hopper, Mark A. Jenkins, Giovana T. Torrezan, Christophe Rosty, Finlay A. Macrae, Ingrid M. Winship, Daniel D. Buchanan, Peter Georgeson

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Comparative Analysis of ChatGPT and Human Expertise in Diagnosing Primary Liver Carcinoma: A Focus on Gross Morphology by Prakasit Sa-ngiamwibool, Thiyaphat Laohawetwanit

“…., with and without a scoring system), pathology residents, and pathologist assistants. The diagnostic accuracy and consistency of each participant group were evaluated. …”
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How Could Static Telepathology Improve Diagnosis in Neuropathology? by Myriam Remmelinck, M. Beatriz S. Lopes, Nathalie Nagy, Sandrine Rorive, Katja Rombaut, Christine Decaestecker, Robert Kiss, Isabelle Salmon

“…Using static telepathology the pathologist could be limited in diagnosis by problems in fields selection.…”
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Current Concepts in the Biopsy of Musculoskeletal Tumors by Costantino Errani, Francesco Traina, Fabrizio Perna, Carlotta Calamelli, Cesare Faldini

“…The choice of biopsy depends on the size, the location of the lesion, and the experience of the pathologist.…”
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Automated recognition and segmentation of lung cancer cytological images based on deep learning. by Qingyang Wang, Yazhi Luo, Ying Zhao, Shuhao Wang, Yiru Niu, Jinxi Di, Jia Guo, Guorong Lan, Lei Yang, Yu Shan Mao, Yuan Tu, Dingrong Zhong, Pei Zhang

“…However, traditional cytological diagnosis requires an experienced pathologist to evaluate all sections individually under a microscope, which is a time-consuming process with low interobserver consistency. …”
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Steatocystoma Multiplex: “Keep me in your Differentials” by Sudha Sharma, V. Anish Chandran, Praveen Kumar Shukla, Ajay Kumar

“…Histopathologic features are characteristic and should be known to the pathologist, to differentiate from other common causes of skin nodules. …”
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ALK-Positive Anaplastic Large Cell Lymphoma: A Diagnostic Dilemma for the Otolaryngologist in a Resource Poor Setting by Nicholas Figaro, Rickhi Ramoutar, Rodolfo Arozarena, Dawn Meyers, Solaiman Juman

“…The morphological diversity with which its anaplastic cells confer make the diagnosis of this hematological entity extremely challenging to the pathologist in a resource poor setting. We present a case of a 35-year-old male with a nasopharyngeal mass and cervical lymphadenopathy and the adversities faced by out otolaryngology department with obtaining the diagnosis of ALK-positive anaplastic large cell lymphoma.…”
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Barrett's Esophagus and Adenocarcinoma by Z.W. Li, A.B.R. Thomson

“…Individual cases of high grade dysplasia should be independently confirmed by another pathologist familiar with dysplasia grading. Esophagectomy should be recommended for those patients with high grade dysplasia whose risk for surgery is outweighed by the possible presence or development of cancer.…”
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Ancillary Testing in Lung Cancer Diagnosis by William Dubinski, Natasha B. Leighl, Ming-Sound Tsao, David M. Hwang

“…With the emergence of new targeted therapies, the pathologist is called upon increasingly to provide not only accurate typing of lung cancers, but also to provide prognostic and predictive information, based on a growing number of ancillary tests, that may have significant impact on patient management. …”
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A Rare Case Diagnosed by Videothoracoscopic Lung Biopsy: Diffuse Pulmonary Meningotheliomatosis by Anton Dzian, Marek Malík, Ľuboš Hamada, Jozef Mičák, Ivana Gregorová, Gabriela Košturiaková

“…These lesions are often detected incidentally as microscopic findings in lung specimens or autopsies examined by a pathologist. We report a case of a 60-year-old male asymptomatic patient presenting with multiple bilateral pulmonary nodules on high-resolution computed tomography and diagnosed by videothoracoscopic surgery. …”
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Metastatic Infiltrating Ductal Carcinoma of the Breast to the Colon: A Case Report and Literature Review by Salih Samo, Muhammed Sherid, Husein Husein, Samian Sulaiman, Jeffrey V. Brower, Seth Alper, Margaret Yungbluth, John A. Vainder

“…Colonic metastatic involvement is a poor prognostic sign, and the pathologist should be informed about the history of the primary breast cancer when examining the pathologic specimens. …”
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