Pharmacological inhibition of key metabolic pathways attenuates Leishmania spp infection in macrophages. by Elaine Carvalho de Oliveira, Rafael Tibúrcio, Gabriela Duarte, Amanda Lago, Léon de Melo, Sara Nunes, Gustavo Gastão Davanzo, Ana Júlia Martins, Bruno Vinagre Ribeiro, Deborah Mothé, Juliana B P Menezes, Patrícia Veras, Natalia Tavares, Pedro M Moraes-Vieira, Cláudia Ida Brodskyn

“…Macrophages represent a fundamental component of the innate immune system that play a critical role in detecting and responding to pathogens as well as danger signals. Leishmania spp. infections lead to a notable alteration in macrophage metabolism, whereby infected cells display heightened energy metabolism that is linked to the integrity of host mitochondria. …”
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A novel isothermal whole genome sequencing approach for Monkeypox Virus by Matthias Licheri, Manon Flore Licheri, Lukas Probst, Cora Sägesser, Pascal Bittel, Franziska Suter-Riniker, Ronald Dijkman

“…Whole genome sequencing (WGS) has been successfully used to keep track of viral evolution during outbreaks or for surveillance of multiple pathogens of public health significance. Current WGS protocols for MPXV are either based on metagenomic sequencing or tiled-PCR amplification. …”
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Macrophages in Tumor Microenvironments and the Progression of Tumors by Ning-Bo Hao, Mu-Han Lü, Ya-Han Fan, Ya-Ling Cao, Zhi-Ren Zhang, Shi-Ming Yang

“…Macrophages are widely distributed innate immune cells that play indispensable roles in the innate and adaptive immune response to pathogens and in-tissue homeostasis. Macrophages can be activated by a variety of stimuli and polarized to functionally different phenotypes. …”
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Evaluation of Halogenated Coumarins for Antimosquito Properties by Venugopala K. Narayanaswamy, Raquel M. Gleiser, Kabange Kasumbwe, Bandar E. Aldhubiab, Mahesh V. Attimarad, Bharti Odhav

“…Mosquitoes are the major vectors of parasites and pathogens affecting humans and domestic animals. The widespread development of insecticide resistance and negative environmental effects of most synthetic compounds support an interest in finding and developing alternative products against mosquitoes. …”
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Roles of Macrophage Subtypes in Bowel Anastomotic Healing and Anastomotic Leakage by Jinyao Shi, Zhouqiao Wu, Ziyu Li, Jiafu Ji

“…Macrophages play an important role in host defense, in addition to the powerful ability to phagocytose pathogens or foreign matters. They fulfill a variety of roles in immune regulation, wound healing, and tissue homeostasis preservation. …”
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Ethnomedicinal, Pharmacological, and Phytochemical Overview of Diplazium esculentum by Abhishek Singh

“…Pharmacologically D. esculentum exhibits multifaceted activities including antioxidant properties antimicrobial effects against a spectrum of pathogens hepatoprotective potential and emerging evidence suggesting antidiabetic activity. …”
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Community-Acquired Pneumonia Requiring Hospitalization among French Guianese Children by Alexandre Cannesson, Narcisse Elenga

“…The main pathogens were respiratory syncytial virus (31.2%), Streptococcus pneumoniae (20.4%), Haemophilus influenzae (11.8%), and Mycoplasma pneumoniae (10.8%). …”
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Automatic Generation of Validated Specific Epitope Sets by Sebastian Carrasco Pro, John Sidney, Sinu Paul, Cecilia Lindestam Arlehamn, Daniela Weiskopf, Bjoern Peters, Alessandro Sette

“…Accurate measurement of B and T cell responses is a valuable tool to study autoimmunity, allergies, immunity to pathogens, and host-pathogen interactions and assist in the design and evaluation of T cell vaccines and immunotherapies. …”
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Diseases impact the performance of maize hybrids in southern Minas Gerais by Guilherme Vieira Pimentel, Luiz Daniel Rodrigues da Silva, Natalia Costa, Amanda Santana, Elisabete da Cruz Silva Watanabe, Silvino Guimarães Moreira

“…The evaluated traits were: severity (%) of foliar and ear diseases, incidence (%) of pathogens in grains, plant and ear height, yield, weight of 100 grains and final stand. …”
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Association of Toll-Like Receptor 2 (TLR2) Expression in Placenta and Intrauterine Exposure to Hepatitis B Virus by Dian Utami, Maisuri T. Chalid, Rina Masadah, Rizalinda Sjahril, Andi Dwi Bahagia Febriani

“…The placenta is a specialized organ that only performs during pregnancy and serves as an immunological barrier in preventing pathogens to reach the fetus. It has been known that toll-like receptors (TLRs) on the placenta respond to antigens, such as zymosan, lipopolysaccharide, and other viral infections. …”
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Detection of Candida tropicalis from camel mastitis by S. A. Esmaeel, S. F. H. Al-Abedi, M. A. Altaliby, Q. T. Al-Obaidi

“…The presence of virulence factors ALST1 and SAPT genes of C. tropicalis in camel milk samples could be considered as transmission vehicle of these pathogens.…”

The multidrug-resistant Candida auris, Candida haemulonii complex and phylogenetic related species: Insights into antifungal resistance mechanisms by Lívia S. Ramos, Pedro F. Barbosa, Carolline M.A. Lorentino, Joice C. Lima, Antonio L. Braga, Raquel V. Lima, Lucas Giovanini, Ana Lúcia Casemiro, Nahyara L.M. Siqueira, Stefanie C. Costa, Célia F. Rodrigues, Maryam Roudbary, Marta H. Branquinha, André L.S. Santos

“…The rise of multidrug-resistant (MDR) fungal pathogens poses a serious global threat to human health. …”
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UV-C light irradiation effects on two rose cultivars infected with Botrytis cinerea by Eduardo Espejel-Maycotte, Ma de Lourdes Arevalo-Galarza, Jose Alfredo Carrillo-Salazar, José Refugio Lomelí-Flores, Victoria Ayala-Escobar, Luis Francisco Salomé-Abarca

“…However, these products have a large accumulation of residues and select strains resistant to pathogens and pesticides. In this context, the irradiation of plants with UV-C light (254 nm) is an effective treatment for the control of several phytopathogens. …”
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A Case of Onychomycosis Caused by Rhodotorula glutinis by Hatice Uludag Altun, Tuba Meral, Emel Turk Aribas, Canan Gorpelioglu, Nilgun Karabicak

“…Rhodotorula spp. have emerged as opportunistic pathogens, particularly in immunocompromised patients. …”
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The Roles of FOXO1 in Periodontal Homeostasis and Disease by Liang Ren, Jing Yang, Jun Wang, Xuedong Zhou, Chengcheng Liu

“…The prevalence of periodontal disease increases with age; more than 70% of adults 65 years and older have periodontal disease. A pathogenic microbial community is required for initiating periodontal disease. …”
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Molecular Characterization of Staphylococci Recovered from Hospital Personnel and Frequently Touched Surfaces in Tianjin, China by Yuting Liu, Liqin Chen, Yuping Duan, Zhen Xu

“…Staphylococci are major hospital-associated pathogens, and the dissemination of methicillin-resistant staphylococci in hospitals poses a great challenge for managing hospital-acquired infections. …”
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Passive Immunoprophylaxis for the Protection of the Mother and Her Baby: Insights from In Vivo Models of Antibody Transport by Yanqun Xu, Iftekhar Mahmood, Lilin Zhong, Pei Zhang, Evi B. Struble

“…Pregnant women are at high risk for infection by pathogens. Vertical transmission of infectious agents, such as Zika, hepatitis B, and cytomegalovirus during pregnancy, remains a public health problem, associated with dire outcomes for the neonate. …”
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Multifunctional probiotic and safety attributes Heyndrickxia coagulans isolated from stingless bee honey by Benyapa Prakit, Rungravee Chaiyod, Kittiya Khongkool, Wankuson Chanasit, Monthon Lertworapreecha

“…They displayed strong antimicrobial activity against various pathogens and demonstrated significant GABA production and antioxidant capabilities. …”
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Microbial Profile of Fresh and Semicooked Nile Tilapia (Oreochromis niloticus) and Hygienic Practice of Fish Handlers in Hawassa, Ethiopia by Fasika Admasu, Abraham Mikru, Kassaye Balkew, Million Adane

“…The microbial load of 40 for each of raw and semicooked fillet samples was estimated by the standard plate count method, and the dominant flora as well as common bacterial pathogens were identified following phenotypic procedures. …”
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Prevalence and intensity of ectoparasites attacked goonch (Bagarius yarelli) captured from Perjaya Dam, Komering River, South Sumatra by Sofian Sofian, Fazril Saputra, Diah Ayu Satyari Utami

“…Another aspect that needs to concern in domestication is the defense of domesticated species from several pathogens, especially parasites because most of wild fish captured from natural habitats are attacked by several parasites. …”
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