Effects of different doses of skt-b vibrio probiotic bacteria addition on survival and growth rate of tiger shrimp (Penaeus monodon) larva by . Widanarni, M.A. Lidaenni, Dinamella Wahjuningrum

“…Vibrio SKT-b is one of the probiotic bacteria candidates that could suppressed the growth of pathogenic bacteria Vibrio harveyi and could increase survival rate of tiger shrimp larva. …”
Get full text

Effect of Zbtb33 gene knockout and bacterial lipopolysaccharide on home cage behavior in mice by N. V. Khotskin, I. E. Sorokin, E. A. Kulikova, A. V.  Kulikov

“…All animals were 11 weeks old, weighed 26 ± 1 g and had SPF (specific pathogen free) status throughout the experiment. The animals of each genotype were divided into three weighted groups of 8 animals each. …”
Get full text

Colchicine Does Not Reduce Abdominal Aortic Aneurysm Growth in a Mouse Model by James Phie, Shivshankar Thanigaimani, Pacific Huynh, Raghuveeran Anbalagan, Corey S. Moran, Robert Kinobe, Joseph V. Moxon, Matt A. Field, Smriti M. Krishna, Jonathan Golledge

“…The nacht domain, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome is upregulated in human abdominal aortic aneurysm (AAA), but its pathogenic role is unclear. The aims of this study were firstly to examine whether the inflammasome was upregulated in a mouse model of AAA and secondly to test whether the inflammasome inhibitor colchicine limited AAA growth. …”
Get full text

Monkeypox: epidemiological situation, diagnostics, prevention, new challenges and problems of our time by Belyakova E.N., Shipulin G.A.

“…Monkeypox (mpox) is a particularly dangerous zoonotic infectious disease, the causative agent of which belongs to the numerous family Poxviridae, subfamily Chordopoxvirinae, genus Orthopoxvirus and belongs to the I pathogenicity group; genetically close to the smallpox virus [1]. …”
Get full text

Molecular mechanisms and therapeutic strategies of Naegleria fowleri Carter (1970): a review of the fatal brain-eating amoeba by N. Datta

“…This review provides a comprehensive overview of the current state of knowledge on N. fowleri, its pathogenic molecular mechanisms, and the biological processes involved in its infection, as well as the challenges and perspectives for future research.…”
Get full text

Antifungal Activity of Gelatin-Tapioca Starch Film and Coating Containing Copper Nanoparticles against Colletotrichum gloeosporioides Causing Anthracnose by Vinh Tien Nguyen, My-Sam Dang-Thi, Khanh Son Trinh

“…This study aimed to fabricate a nontoxic coating containing copper nanoparticles (CuNPs) to protect fruits from pathogenic Colletotrichum gloeosporioides causing anthracnose on several tropical fruits. …”
Get full text

Deletion of pagL and arnT genes involved in LPS structure and charge modulation in the Salmonella genome confer reduced endotoxicity and retained efficient protection against wild-... by Ram Prasad Aganja, Jun Kwon, Amal Senevirathne, John Hwa Lee

“…However, existing vaccines, like the SG9R strain, have limitations, including residual virulence and potential reversion of pathogenicity. This study aims to develop safer and more effective SG vaccine strains through targeted genetic modifications, focusing on genes involved in lipopolysaccharide (LPS) biosynthesis and modification. …”
Get full text

High Seropositivity of Brucella melitensis Antibodies among Pregnant Women Attending Health Care Facilities in Mwanza, Tanzania: A Cross-Sectional Study by Helmut A. Nyawale, Michael Simchimba, Joseph Mlekwa, Fridolin Mujuni, Elieza Chibwe, Prosper Shayo, Elifuraha B. Mngumi, Khadija S. Majid, Mtebe Majigo, Stephen E. Mshana, Mariam M. Mirambo

“…Brucella melitensis (B. melitensis), the most pathogenic species is responsible for several pregnancy adverse outcomes in both humans and animals. …”
Get full text

Prevalence of eimeria species in sheep in eskişehir province by Mustafa Eser, Ahmet Göksu, Hatice Çiçek, Mahmut Sinan Erez, Hasan Çiçek

“…<p> <b>Conclusion:</b> The high prevalence of pathogenic species shows that Coccidiosis is a risk for sheep raised in Eskişehir province. …”
Get full text

Escherichia coli in septic arthritis: prevalence and antibiotics susceptibility patterns by Masroora Ali Khan, Muhammad Kamran Taj, Zahid Khan, Imran Taj, Muhammad Naeem, Saima Azam

“…Sequence analysis using the Basic Local Alignment Search Tool found high similarity with pathogenic E. coli from Egypt and China. The identified E. coli strain showed significant resistance to common antibiotics: amoxicillin, amoxicillin-clavulanate, ceftriaxone, sulfamethoxazole/trimethoprim, gentamicin, tetracycline, and erythromycin. …”
Get full text

Pathogenetic Substantiation of the Therapeutic Impact on Microbiota in Irritable Bowel Syndrome by Yu. O. Shulpekova, G. H. Babaeva, V. Yu. Rusyaev

“…Reduced microbial diversity increases susceptibility to intestinal infections and parasitoses, including those caused by protozoa conditionally pathogenic for adults, such as Blastocystis hominis hominis, Dientamoeba fragilis, Giardia lamblia. …”
Get full text

The Effect of Banana Bacteria Wilt on The Socio-Economic Welfare of Farmers in Ruhinda Sub-County Rukungiri District . by Tayebwa, Rameka

“…The highest number of respondents mentioned source of mulch for maintaining and improving soil fertility, the lowest number of respondents mentioned that the disease has led to increased poverty among households and the study continued on possible measures to control banana bacteria wilt in Ruhinda sub-county Rukungiri district, the highest number of respondents mentioned heating garden tools such as hoes, machete, knives and slashers over a fire until the metal is too hot to touch is also effective in killing the bacteria, the lowest number of respondents talked of timely removal of male buds with a forked stick is important in where insect vector that visit the diseased flower parts carry the pathogen. The study recommended that there should be quarantine enforcement by the government agencies to prevent spread of banana bacteria wilt to non-infected areas, there should be policies on the use of clean planting materials and regular inspection/screening for the approved banana nurseries to dispense banana bacteria wilt disease free materials and there should be production of free banana bacteria wilt such as banana tissue culture, train and encourage more banana nurseries producers/tissue culture hardening nurseries to avail clean banana planting materials.…”
Get full text

Neutralizing antibody immune correlates in COVAIL trial recipients of an mRNA second COVID-19 vaccine boost by Bo Zhang, Youyi Fong, Lauren Dang, Jonathan Fintzi, Shiyu Chen, Jing Wang, Nadine G. Rouphael, Angela R. Branche, David J. Diemert, Ann R. Falsey, Daniel S. Graciaa, Lindsey R. Baden, Sharon E. Frey, Jennifer A. Whitaker, Susan J. Little, Satoshi Kamidani, Emmanuel B. Walter, Richard M. Novak, Richard Rupp, Lisa A. Jackson, Chenchen Yu, Craig A. Magaret, Cindy Molitor, Bhavesh Borate, Sydney Busch, David Benkeser, Antonia Netzl, Derek J. Smith, Tara M. Babu, Angelica C. Kottkamp, Anne F. Luetkemeyer, Lilly C. Immergluck, Rachel M. Presti, Martín Bäcker, Patricia L. Winokur, Siham M. Mahgoub, Paul A. Goepfert, Dahlene N. Fusco, Robert L. Atmar, Christine M. Posavad, Jinjian Mu, Mat Makowski, Mamodikoe K. Makhene, Seema U. Nayak, Paul C. Roberts, Peter B. Gilbert, Dean Follmann, Coronavirus Variant Immunologic Landscape Trial (COVAIL) Study Team

Get full text

Protocol for a Phase 2 randomized controlled patient-assessor blinded study: efficacy and safety of combined cortical and cerebellar dual-target transcranial magnetic stimulation f... by Jing Xu, Na Cao, Yan Qu, Suhang Shang, Xincheng Liu, Xuexin Wang, Fangfang Hu, Xuerong Bai, Qiumin Qu, Meng Zhang, Hongmei Cao

“…Abnormal cerebello-thalamo-cortical (CTC) loop function are thought to be significant pathogenic causes of ET, with the cerebellum and cortex are common targets for ET treatment. …”
Get full text

Hexagonal zinc oxide nanoparticles: a novel approach to combat multidrug-resistant Enterococcus faecalis biofilms in feline urinary tract infections by Alaa H. Sewid, Alaa H. Sewid, Mohamed Sharaf, Mohamed Sharaf, Azza S. El-Demerdash, Sherif M. Ragab, Fatimah O. Al-Otibi, Mohamed Taha Yassin, Chen-Guang Liu

“…IntroductionEnterococcus faecalis, a common inhabitant of the feline gastrointestinal tract, has emerged as a significant pathogen causing urinary tract infections (UTIs) in domestic cats. …”
Get full text

Transcriptome-wide dynamics of m6A methylation in ISKNV and Siniperca chuatsi cells infected with ISKNV by Qijin Miao, Jing Jiang, Siyou Huang, Jie Gao, Qingqing Liu, Rui Zheng, Yiling Kang, Changjun Guo, Jianguo He, Junfeng Xie

“…However, the impact of m6A RNA methylation on the pathogenicity of ISKNV remains unexplored. Here, methylated RNA immunoprecipitation sequencing (MeRIP-seq) coupled with RNA sequencing (RNA-seq) was used to systematically detect variations in m6A methylation and gene expression between ISKNV-infected and noninfected MFF-1 cells, followed by functional enrichment and co-expression joint analysis. …”
Get full text

Updates on the molecular spectrum of MEFV variants in lebanese patients with Familial Mediterranean Fever by Rudy Feghali, José-Noel Ibrahim, Nabiha Salem, Romy Moussallem, Ghina Hijazi, Charbel Attieh, Tony Yammine, Alain Chebly, Alain Chebly

“…Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disorder, particularly present in the Mediterranean populations, and associated with pathogenic variants in the MEFV gene. This study aims to investigate the distribution of MEFV variants in a large cohort of Lebanese patients, and to explore the genotype-phenotype correlation among affected individuals. …”
Get full text

Assessing the effect of beta-propiolactone inactivation on the antigenicity and immunogenicity of cluster 2.1 duck Tembusu virus by Kanana Rungprasert, Wikanda Tunterek, Phornphisut Areeraksakul, Duangduean Prakairungnamthip, Chalida Sri-in, Navapon Techakriengkrai, Wijit Banlunara, Christine A. Jansen, Teerawut Nedumpun, Aunyaratana Thontiravong

“…Duck Tembusu virus (DTMUV), an emerging avian pathogenic flavivirus, causes severe neurological disorders and acute egg drop syndrome in ducks. …”
Get full text

Retrospective Evaluation of Toxoplasma gondii Test Results in Patients Applying to A Research Hospital by Sedef Zeliha Öner, İlknur Kaleli, Melek Demir, Ahmet Çalışkan, Ergun Mete, Hande Şenol, Çağrı Ergin

“…Objective: This study retrospectively evaluates our laboratory Toxoplasma gondii immunoglobulin (Ig)M, IgG antibody and avidity test results to determine the distribution of the pathogen according to sex, age, clinics and years. …”
Get full text

Clinical and microbiological analysis of risk factors for breakthrough bloodstream infection during Tigecycline Therapy by Sol Jin, So Yun Lim, Yun Woo Lee, Heungsup Sung, Mi-Na Kim, Seongman Bae, Jiwon Jung, Min Jae Kim, Sung-Han Kim, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Eun Hee Song, Yong Pil Chong

“…The most frequently identified pathogen in breakthrough BSI was Klebsiella pneumoniae (22.8%), followed by Candida species (17.1%), Pseudomonas aeruginosa (16.3%), and Acinetobacter baumannii (14.6%). …”
Get full text