Comparison of chromogenic and cysteine lactose electrolyte deficient agar for identification of uropathogens in Gujarat, India by Nisha Vadivelu, Rashmika D. Parmar, Hitesh Shingala, Krunal D. Mehta

“…The performance of chromogenic UTI agar was assessed for pathogen identification, detection of polymicrobial infections, time to results, and cost-effectiveness. …”
Get full text

Physiological and transcriptomic analysis of the effect of overexpression of the NTPIP2;4 gene on drought tolerance in tobacco by Xu Luo, Yuanshuai Shi, Jie Tan, Tao Long, Juntao Song, Yang Liu

“…The DEGs were enriched mainly in the plant MAPK signaling pathway, the plant hormone signal transduction pathway, amino sugar and nucleotide sugar metabolism, starch and sucrose metabolism and plant-pathogen interaction pathways. We also investigated the drought pathway of MAPK pathway and the auxin pathway mechanism of plant hormone signal transduction pathway, and found that the transcript levels of the genes of the relevant pathways changed, and hypothesized that NtPIP2;4 might regulate the drought resistance of plants through the expression of the relevant genes induced by auxin. …”
Get full text

Avian influenza overview September–December 2024 by European Food Safety Authority, European Centre for Disease Prevention and Control, European Union Reference Laboratory for Avian Influenza, Leonidas Alexakis, Hubert Buczkowski, Mariette Ducatez, Alice Fusaro, Jose L. Gonzales, Thijs Kuiken, Karl Ståhl, Christoph Staubach, Olov Svartström, Calogero Terregino, Katriina Willgert, Miguel Melo, Lisa Kohnle

“…Abstract Between 21 September and 6 December 2024, 657 highly pathogenic avian influenza (HPAI) A(H5N1) and A(H5N5) virus detections were reported in domestic (341) and wild (316) birds across 27 countries in Europe. …”
Get full text

Analyses of urogenital Mycoplasma hominis and Ureaplasma urealyticum infections and drug sensitivity in 296 patients by CHEN Junwei, HUANG Sheng, QIU Wei, XIAO Yupeng

“…[Conclusions] Females are more likely to have urogenital tract mycoplasma infections than males, and Uu is the main pathogen. The three types of infections are sensitive to doxycycline and minocycline. …”
Get full text

Gut colonization of Bacteroides plebeius suppresses colitis-associated colon cancer development by Hung-Lin Chen, Po-Yuan Hu, Chang-Shan Chen, Wei-Han Lin, Daniel K. Hsu, Fu-Tong Liu, Tzu-Ching Meng

“…We also showed that colonization of B. plebeius suppressed the colon tumor development induced by azoxymethane/dextran sulfate sodium in specific-pathogen-free mice, coinciding with a reduced abundance of Muribaculaceae sp., Closteridale sp., and Bilophila sp. …”
Get full text

Global knowledge gaps in acute febrile illness etiologic investigations: A scoping review. by Chulwoo Rhee, Grishma A Kharod, Nicolas Schaad, Nathan W Furukawa, Neil M Vora, David D Blaney, John A Crump, Kevin R Clarke

“…<h4>Conclusions</h4>Wider implementation of standardized AFI reporting methods, with multi-pathogen disease detection, could improve comparability of study findings, knowledge of the range of AFI etiologies, and their contributions to the global AFI burden. …”
Get full text

Genetic analysis of scab disease resistance in common bean (Phaseolus vulgaris) varieties using GWAS and functional genomics approaches by Shadrack Odikara Oriama, Benard W. Kulohoma, Evans Nyaboga, Y. O. Masheti, Reuben Otsyula

“…Abstract Introduction Scab is a fungal disease of common beans caused by the pathogen Elsinoë phaseoli. The disease results in major economic losses on common beans, and there are efforts to develop integrated pest management strategies to control the disease. …”
Get full text

Synthesizing hybrid copper phosphate (Cu3(PO4)2) nanoflowers using Cu+2 and shed snakeskin: antioxidant, antibacterial, anticancer, guaiacol, anionic, and cationic dye degradation... by Cagri Caglar Sinmez, Fatih Doğan Koca

“…Cu@SSS hNFs demonstrated antibacterial properties towards Gram (-/ +) pathogen strains (MIC: 60 µg/ml). The catalytic and antimicrobial properties of hNFs were mentioned by the Fenton reaction. …”
Get full text

Study of Antibacterial Activity of Root Bark, Leaves, and Pericarp Extracts of Diploknema butyracea and Evaluation of Prospective Antioxidant Activity by Alisha Karki Chhetry, Subhila Dhakal, Lalita Chaudhary, Khimdhoj Karki, Ram Bahadur Khadka, Gautam Prasad Chaudhary, Tonking Bastola, Amrit Poudel, Pramod Aryal, Jitendra Pandey

“…Overall, our study showed that the root bark, pericarp, and leaves extract of D. butyracea evinced prominent antibacterial properties against various pathogenic bacterial strains.…”
Get full text

Bacterial Profile among Patients with Suspected Bloodstream Infections in Ethiopia: A Systematic Review and Meta-Analysis by Birhan Alemnew, Habtamu Biazin, Asmamaw Demis, Melese Abate Reta

“…Furthermore, we found a remarkable variation in the pathogen distribution across the study setting.…”
Get full text

CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation. by John T Loffredo, Thomas C Friedrich, Enrique J León, Jason J Stephany, Denise S Rodrigues, Sean P Spencer, Alex T Bean, Dominic R Beal, Benjamin J Burwitz, Richard A Rudersdorf, Lyle T Wallace, Shari M Piaskowski, Gemma E May, John Sidney, Emma Gostick, Nancy A Wilson, David A Price, Esper G Kallas, Helen Piontkivska, Austin L Hughes, Alessandro Sette, David I Watkins

“…<h4>Conclusions</h4>Together, our data suggest that Mamu-B*08-restricted CD8+ T cell responses effectively control replication of pathogenic SIV(mac)239. All seven regions encoding Mamu-B*08-restricted CD8+ T cell epitopes also exhibit amino acid replacements typically seen only in the presence of Mamu-B*08, suggesting that the variation we observe is indeed selected by CD8+ T cell responses. …”
Get full text

A multi-strain human skin microbiome model provides a testbed for disease modeling by Angela L. Maloney, Tyler Crawford, Jordan Hurlbut, Monica Martinez, Thomas J. Mulhern, Elizabeth L. Wiellette, Else M. Vedula, Vidhya Vijayakumar

“…The skin microbiome plays a critical role at the interface between the human epidermis and the environment, providing colonization resistance against pathogenic strains, training host immunity, and supporting epithelial turnover. …”
Get full text

First two mitochondrial genomes for the order Filobasidiales reveal novel gene rearrangements and intron dynamics of Tremellomycetes by Qiang Li, Zhijie Bao, Ke Tang, Huiyu Feng, Wenying Tu, Lijiao Li, Yunlei Han, Mei Cao, Changsong Zhao

Get full text

Comparison of ultraviolet C light and isopropyl alcohol for the disinfection of cellular phones in a paediatric intensive care unit setting by L Thomas, J John, H Lochan

“…A considerable proportion of cellular phones (cell phones) used by healthcare workers (HCWs) have been shown to be contaminated with pathogenic micro-organisms, making these devices reservoirs to infect susceptible patients. …”
Get full text

Genetic diversity of barley accessions from East Asian countries in terms of resistance to powdery mildew by R. A. Abdullaev, K. A. Lukina, B. A. Batasheva, O. N. Kovaleva, E. E. Radchenko

“…Golovin ex Speer f. sp. hordei Marchal. The pathogen can overcome a cultivar’s resistance, resulting in significant harvest losses. …”
Get full text

Isolation and Antifungal Susceptibility of Candida spp. from Pediatric Patients in Kurdistan of Iraq by Mohammed Salah Bahi, Khattab Ahmed Mustafa Shekhany

“…Candida species are considered the most common opportunistic human fungal pathogen due to the presence of various virulence factors, including its ability to form a biofilm that aids in oral candidiasis. …”
Get full text

Molecular subtype of ovarian clear cell carcinoma: an analysis of 80 Chinese patients using the TCGA molecular classification of endometrial cancer by Wei Chen, Lu Yan, Qin Li, Shuling Zhou, Ting Hou, Huijuan Yang, Shuang Ye

“…Results The most common mutated genes were ARID1A (49%) and PIK3CA (48%). No pathogenic POLE mutations were detected. MSI-high (MSI-H) tumours were observed in 5 (6.3%) patients. …”
Get full text

Assessments of Antibacterial Effects of Aqueous-Ethanolic Extracts of Sida rhombifolia’s Aerial Part by Demeke Debalke, Mastewal Birhan, Amebaye Kinubeh, Muluken Yayeh

“…In addition to this, the antibacterial activity of the plant extract was evaluated on five pathogenic bacteria species using agar well diffusion method at different concentrations of plant extracts. …”
Get full text

Evaluation of Leea rubra Leaf Extract for Oxidative Damage Protection and Antitumor and Antimicrobial Potential by Nibedita Das, Sanowar Hossain, Jaytirmoy Barmon, Shahnaj Parvin, Mahadi Hasan, Masuma Akter, Ekramul Islam

“…Antimicrobial activity was evaluated against two pathogenic resistant microorganisms (Escherichia coli and Pseudomonas aeruginosa), and the highest antimicrobial activity was observed against Pseudomonas spp. …”
Get full text

Serotype distribution and antimicrobial susceptibility of Streptococcus suis isolates from porcine diagnostic samples in Hungary, 2020–2023 by Ervin Albert, István Emil Kis, Krisztián Kiss, Katalin K-Jánosi, Tamás Révész, Imre Biksi

“…Abstract Background Streptococcus suis (S. suis) is a major swine pathogen and a significant zoonotic agent, causing substantial economic losses in the swine sector and having considerable public health importance. …”
Get full text