Evolutive radiological findings in a case of coccidioidal infection in an immunocompetent male: a case report by Paolo La Montanara, Annamaria Albergo, Loredana Capozzi, Roberto Castellana, Gerardo Cazzato, Carmela De Carlo, Sofia Denicolò, Antonella Netti, Mariacristina Poliseno, Enrica Maddalena Ranieri, Caterina Romano, Annalisa Rossiello, Stefania Stolfa, Alessandra Tripoli, Giuseppe Vella

“…Conclusions While an acute, benign, and self-eradicating lung infection is the predominant presentation for most cases of coccidioidomycosis, a small percentage of patients experience a devastating extrapulmonary condition, which can include arthritis. The pathogenic mechanism of bone involvement is unknown, and it often remains untreated. …”
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MIRAGE syndrome: a case report of de novo SAMD9 c.884del p.(Pro295GlnfsTer104) variant and a novel phenotype of pyloric stenosis by Mohamad M. Assker, Mahdia Al Haidar, Marwan Faris, Ahmed Emara, Yousef Al Abrach, Maryam Al Shehhi

“…(Pro295GlnfsTer104)) and an X-linked pathogenic duplication affecting 21 genes. These findings confirmed the diagnosis of MIRAGE syndrome. …”
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Exosomes in neuron-glia communication: A review on neurodegeneration by Naeimeh Akbari-Gharalari, Sina Khodakarimi, Farshad Nezhadshahmohammad, Mohammad Karimipour, Abbas Ebrahimi-Kalan, Jiagian Wu

“…Results: Although the immediate practical applications of exosomes are somewhat limited, their potential as carriers of pathogenic attributes offers promising opportunities for the development of precisely targeted therapeutic strategies for neurological disorders. …”
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Anticancer, Antioxidant, Antimicrobial Activities, and HPLC Analysis of Alcoholic Extracts of Parthenocissus quinquefolia L. Plant Collected from Çanakkale by Sevil Kalın, Ersin Karabacak, Pınar Ilgın, Alper Önder, Özlem Maraba, Ferah Cömert Önder

“…The antifungal activity was determined against Candida albicans as fungal pathogen. The cell apoptosis with methanol extract was obtained between 20 µg/mL and 70 µg/mL for 48 h and 72 h treatments by Hoechst 33258 staining of nuclei under a fluorescence microscopy. …”
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Cells and Cytokines in Milk of Subclinically Infected Bovine Mammary Glands after the Use of Immunomodulatory Composition GLP 810 by Gundega Gulbe, Māra Pilmane, Vaira Saulīte, Simona Doniņa, Jevgenijs Jermolajevs, Lilija Peškova, Anda Valdovska

“…A reduction in the number of pathogenic bacteria was also detected. The analyses of tumour necrosis factor-alpha, interleukin-10, and beta-defensin-2 revealed that the production of the aforementioned cytokines significantly increased, whereas no significant effects on interleukin-1 and caspase-6 expression in milk leukocytes were recorded. …”
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Staphylococcus saprophyticus Recovered from Humans, Food, and Recreational Waters in Rio de Janeiro, Brazil by Viviane Santos de Sousa, Ana Paula de Souza da-Silva, Leif Sorenson, Raphael Paiva Paschoal, Renata Fernandes Rabello, Eloiza Helena Campana, Márcia Soares Pinheiro, Lyssa Oliveira Ferreira dos Santos, Natacha Martins, Ana Carolina Nunes Botelho, Renata Cristina Picão, Sérgio Eduardo Longo Fracalanzza, Lee Woodland Riley, George Sensabaugh, Beatriz Meurer Moreira

“…Staphylococcus saprophyticus is an important agent of urinary tract infection (UTI) in young women, but information about this pathogen in human microbiota and in common environment is lacking. …”
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ALCAM is an entry factor for severe community acquired Pneumonia-associated Human adenovirus species B by Yusang Xie, Hong Mei, Wei Wang, Xiao Li, Pengfei Hu, Xingui Tian, Rong Zhou, Jia Liu, Jieming Qu

“…Abstract Human adenovirus (HAdV) is a widely spread respiratory pathogen that can cause infections in multiple tissues and organs. …”
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Resistance of barley cultivars approved for use in Russia to harmful organisms and toxic aluminum ions by R. A. Abdullaev, B. A. Batasheva, N. V. Alpatieva, M. A. Chumakov, E. E. Radchenko, O. N. Kovaleva, O. V. Yakovleva

“…The specificity of the host– pathogen interactions necessitates a constant search for new donors of resistance for breeding, and phytosanitary monitoring of cultivars.Materials and methods. …”
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Behavior of Olive Genotypes Against Quick Decline Syndrome (QDS) Caused by <i>Xylella fastidiosa</i> subsp. <i>pauca</i> in Apulia by Mariangela Carlucci, Michele Antonio Savoia, Pompea Gabriella Lucchese, Valentina Fanelli, Isabella Mascio, Francesco Luigi Aurelio, Monica Marilena Miazzi, Andrea Pacifico, Cinzia Montemurro, Franco Nigro

“…<i>pauca</i> (<i>Xfp</i>), a quarantine pathogen in the European Union, severely threatens Mediterranean olive production, especially in southern Italy, where Olive Quick Decline Syndrome (OQDS) has devastated Apulian olive groves. …”
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Gut Microbiota as Emerging Players in the Development of Alcohol-Related Liver Disease by Wei Li, Wenkang Gao, Shengqi Yan, Ling Yang, Qingjing Zhu, Huikuan Chu

“…In patients with alcohol-related liver disease, the relative abundance of pathogenic bacteria, including <i>Enterococcus faecalis</i>, increases and is positively correlated with the level of severity exhibited by alcohol-related liver disease. …”
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Ophiostomatalean Fungi (Ascomycota, Ophiostomatales) Associated with Three Beetles from <i>Pinus sylvestris</i> var. <i>mongolica</i> in Heilongjiang, China by Zheng Wang, Caixia Liu, Yingjie Tie, Xiuyue Song, Huimin Wang, Quan Lu

“…Certain fungi from the ophiostomatalean contribute to forest pest outbreaks and can be pathogenic to pine trees. However, only a limited number of ophiostomatalean fungi associated with beetles infesting <i>Pinus sylvestris</i> var. …”
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What makes an epidemic a disaster: the future of epidemics within the EM-DAT International Disaster Database by Margo Tonnelier, Damien Delforge, Regina Below, Juan Armando Torres Munguía, Claude Saegerman, Valentin Wathelet, Joris A. F. van Loenhout, Niko Speybroeck

“…However, they proposed pathogen-based criteria and agreed that disruption to society, especially to the healthcare system, serves as a determinant of epidemic disasters. …”
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Insight into the codon usage patterns and adaptation of Tembusu Virus by Fucheng Guo, Huiming Tan, Jinjin Yang, Rumin Jia, Ruichen Wang, Lie Wu, Fengzhi Pan, Kai Kang, Weitian Xie, Youquan Li, Kewei Fan

“…This work advances our understanding of the basic biology underlying TMUV epidemiology, pathogenicity, and species-specific adaptation.…”
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Lack of Proinflammatory Cytokine Interleukin-6 or Tumor Necrosis Factor Receptor-1 Results in a Failure of the Innate Immune Response after Bacterial Meningitis by Lea-Jessica Albrecht, Simone C. Tauber, Julika Merres, Eugenia Kress, Matthias B. Stope, Sandra Jansen, Thomas Pufe, Lars-Ove Brandenburg

“…The most frequent pathogen that causes bacterial meningitis is the Gram-positive bacterium Streptococcus pneumoniae. …”
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Multiple gene-deletion vaccinia virus Tiantan strain against mpox by Yilong Zhu, Dapeng Li, Renshuang Zhao, Minghua Chen, Yue Li, Xia Yang, Hongyue Mao, Xiao Li, Yiquan Li, Chao Shang, Xianzhu Xia

“…Abstract Monkeypox virus (MPXV) is an important zoonotic pathogenic virus, which poses serious threats to public health. …”
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Necrostatin-1 Alleviates Diffuse Pulmonary Haemorrhage by Preventing the Release of NETs via Inhibiting NE/GSDMD Activation in Murine Lupus by Xinai Han, Xiaoming Zhang, Rui Song, Shiqi Li, Shujing Zou, Quanguang Tan, Tianyang Liu, Shugeng Luo, Zhe Wu, Hongyu Jie, Jinhong Wang

“…Neutrophil extracellular traps (NETs) contain numerous antigens and proinflammatory substances that directly damage the vascular endothelium and aggravate vascular inflammation, which is considered an important pathogenic factor of DAH in SLE. Therefore, blocking the release of NETs from neutrophils is an important target for the treatment of DAH in SLE. …”
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Clinical efficacy of Methylene Blue mediated antimicrobial Photodynamic Therapy (PDT) using 680 nm Diode Laser in patients undergoing Open Flap Debridement: An Original Research by Soundarya Singh, Manisha Rout, Mayur Kaushik, Shilpa Sharma, Aprajita Srivastava

“…PDT could be a useful adjunct to mechanical as well as antibiotics in eliminating periodontal-pathogenic bacteria. Methods: The patients selected were randomly divided into two groups. …”
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Evaluating the Effect of Chloroform and Water Extract of Satureja khuzistanica on the Expression of Bcl-2 and Bax in Gastric Cancer Cell Line by Bagher Biglak, Asghar Tanomand, Leyla Açik, Farzad Arjomandi Rad, Gholamreza Shahsavari, Saman Kazemi, Hossein Soltanzadeh

“…Methods: The antimicrobial activities of chloroform and water extracts were screened against pathogenic bacteria [Helicobacter pylori (H. pylori)]. …”
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Population features of prevalence and clinical-diagnostic role of NOD2 gene polymorphisms associated with Crohn’s disease by D. A. Kuznetsova, M. V. Merzlyakov, G. V. Vavin, A. S. Razumov, V. L. Emanue

“…It will allow not only to increase efficacy of early diagnosis and the CD risk prognosis, but to define environmental factors affecting clinical utilization of genetic factors that is a premise for development of pathogenic justified management algorithm encompassing both populationbased and regional factors.…”
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Nanocomplex hyaluronic acid/ganciclovir@ZIF-8 for ganciclovir efficient delivery and targeted anti-KSHV treatment by Fangling Li, Chengjing Liu, Wenyi Gu, Qianhe Xu, Dongmei Li, Dongdong Cao, Zhiyong Liu

“…In addition, HA/GCV@ZIF-8 not only suppresses expression of KSHV pathogenic genes with less drug dose, but also inhibits the ability of cell proliferation and migration. …”
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