Suggested Topics within your search.
Suggested Topics within your search.
- Microbiology 2
- Biology 1
- Clinical 1
- Human Microbial 1
- Infections 1
-
4801
Phenotypic Characterization and Antibiotic Resistance Patterns of Extended-Spectrum β-Lactamase- and AmpC β-Lactamase-Producing Gram-Negative Bacteria in a Referral Hospital, Saudi...
Published 2019-01-01“…Background. Emergence of pathogenic bacteria carrying β-lactamase-resistant determinants has become a major health problem in the hospital setting. …”
Get full text
Article -
4802
TAB2 deficiency induces dilated cardiomyopathy by promoting mitochondrial calcium overload in human iPSC-derived cardiomyocytes
Published 2025-02-01“…More importantly, the discovery of a unique pathogenic pathway introduces a new notion for the future management of dilated cardiomyopathy.…”
Get full text
Article -
4803
Recalcitrant Female Pattern Hair Loss Like Alopecia Unveils Unexpected Rare Entity
Published 2025-01-01“…Genetic testing confirmed a heterozygous pathogenic variant in the HRURF gene, associated with autosomal dominant Marie Unna Hereditary Hypotrichosis. …”
Get full text
Article -
4804
Exome sequencing reveals IFT172 variants in patients with non-syndromic cholestatic liver disease.
Published 2023-01-01“…Nasopharyngeal swab mRNA was analysed to address variant pathogenicity in two families.<h4>Results</h4>WES revealed biallelic variation in 3 ciliopathy genes (PKHD1, TMEM67 and IFT172) in 4 clinically unrelated index subjects (3 children and 1 adult), heterozygosity for a known variant in PPOX in one adult index subject, and homozygosity for an unreported splice-site variation in F11R in one child. …”
Get full text
Article -
4805
Antimicrobial and antioxidant study of combined essential oils of Anethum Sowa Kurz. and Trachyspermum ammi (L.) along with quality determination, comparative histo-anatomical feat...
Published 2024-11-01“…Combined essential oils (EOs 1 + 2) of both fruits showed excellent antimicrobial activity against various clinical pathogenic strains such as K. pneumoniae at 10 µL/mL, S. aureus at 2.5 µL/mL, E. coli and E. faecalis at 1.25 µL/mL, and MRSA and Bcereus at 0.625 µL/mL and (C) albicans at 0.312 µL/mL as the MIC. …”
Get full text
Article -
4806
Advancing dental biofilm models: the integral role of pH in predicting S. mutans colonization
Published 2025-01-01“…Our work demonstrates the utility of individual-based models for simulating diverse conditions affecting dental biofilm scenarios, such as the frequency of glucose intake, sucrose pulsing, or integration of pathogenic or probiotic species. Although in silico models are reductionist approaches, they have the advantage of not being limited in the scenarios they can test by the ethical consideration of an in vivo system, thus significantly contributing to dental biofilm research.…”
Get full text
Article -
4807
-
4808
Clinical and endoscopical and morphofunctional scores in evaluation of development of gastroesophageal reflux disease in various age groups
Published 2012-09-01“…In development of the catarrhal form of GERD in patients of young age it is possible to consider following basic pathogenic factors: chronic H. pylori-associated gastritis; lower esophageal sphincter incompetence closely related to nutritional deficiency; long-term exposure to acidic gastric contents at gastroesophageal reflux due to disorders of motor function of the esophagus on a background of hyperplasia of NO-synthase and endothelin-1-producing stomach cells. …”
Get full text
Article -
4809
Optimal Vase Solution for <i>Gerbera hybrida</i> Cut Flower Keeping Fresh by Activating SA and Cytokinin Signaling and Scavenging Reactive Oxygen Species
Published 2024-12-01“…., <i>GhIPT1</i> and <i>GhIPT9</i>), salicylic acid signaling related to pathogen defense (e.g., <i>GhTGA1</i>, <i>GhTGA4</i>, <i>GhNPR1</i>, and <i>GhRBOHA</i>), and plant wax synthesis and stress response (e.g., <i>GhKCS5</i>, <i>GhCUT1</i>, and <i>GhKCS6</i>). …”
Get full text
Article -
4810
Diversity in Adaptive Evolution of Methicillin-Resistant Staphylococcus aureus Clinical Isolates Under Exposure to Continuous Linezolid Stress in vitro
Published 2025-02-01“…Tala Han,1 Ting Jia,1 Junrui Wang1,2 1Department of Laboratory Medicine, Affiliated Hospital of Inner Mongolian Medical University, Hohhot, 010050, People’s Republic of China; 2Inner Mongolia Key Laboratory of Clinical Pathogenic Microorganism, The Affiliated Hospital of Inner Mongolian Medical University, Hohhot, 010050, People’s Republic of ChinaCorrespondence: Junrui Wang, Clinical Laboratory, Affiliated hospital of Inner Mongolian Medical University, Hohhot, 010050, People’s Republic of China, Tel +86 04713451315, Email wangjunrui123@yeah.netBackground: Linezolid resistance in methicillin-resistant Staphylococcus aureus (MRSA) was reported frequently in recent years, but the mechanism underlying this process was less reported, especially for clinical isolates with different genetic background. …”
Get full text
Article -
4811
Molecular genetic detection and differentiation of <i>Xanthomonas oryzae</i> pv. <i>oryzicola</i>, bacterial leaf streak agents of rice
Published 2022-10-01“…The quarantine status and high severity of the pathogen require a highly eff icient, fast and precise diagnostic method. …”
Get full text
Article -
4812
Staphylococcus aureus vesicles impair cutaneous wound healing through p38 MAPK-MerTK cleavage-mediated inhibition of macrophage efferocytosis
Published 2025-01-01“…Abstract Background Staphylococcus aureus, a known contributor to non-healing wounds, releases vesicles (SAVs) that influence the delicate balance of host-pathogen interactions. Efferocytosis, a process by which macrophages clear apoptotic cells, plays a key role in successful wound healing. …”
Get full text
Article -
4813
Detection and Characterization of <i>Escherichia coli</i> and <i>Escherichia coli</i> O157:H7 in Human, Animal, and Food Samples from Kirkuk Province, Iraq
Published 2025-01-01“…These findings may raise awareness of the risks associated with this pathogen, helping to reduce the incidence of <i>E. coli</i>-related diseases and to protect human health.…”
Get full text
Article -
4814
Anti-GAPDH Autoantibody Is Associated with Increased Disease Activity and Intracranial Pressure in Systemic Lupus Erythematosus
Published 2019-01-01“…The recent studies on the anti-GAPDH autoantibodies suggested its potential pathogenic roles in NPSLE. However, the clinical relevance of the anti-GAPDH autoantibodies in patients with SLE is still elusive. …”
Get full text
Article -
4815
Antibiotics Resistance in Escherichia coli Isolated from Livestock in the Emirate of Abu Dhabi, UAE, 2014–2019
Published 2022-01-01“…Escherichia coli (E. coli) is a zoonotic pathogen that showed growing resistance to antibiotics. …”
Get full text
Article -
4816
In Silico Identification of New Anti-SARS-CoV-2 Main Protease (Mpro) Molecules with Pharmacokinetic Properties from Natural Sources Using Molecular Dynamics (MD) Simulations and Hi...
Published 2022-01-01“…The quick development of novel therapeutic compounds is required in the fight against such pathogenic agents. Unfortunately, the traditional drug development methods are time-consuming and expensive. …”
Get full text
Article -
4817
Transcriptome, miRNA, and degradome sequencing reveal the leaf stripe (Pyrenophora graminea) resistance genes in Tibetan hulless barley
Published 2025-01-01“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of the 8,916 DEGs identified many significantly enriched categories and pathways, of which a plant–pathogen interaction pathway, containing a total of 102 genes (100 known genes and two novel genes), was found, that was very important for the study of the leaf stripe resistance mechanism. …”
Get full text
Article -
4818
Understanding the clinical and molecular epidemiological characteristics of carbapenem-resistant Acinetobacter baumannii infections within intensive care units of three teaching ho...
Published 2025-01-01“…Abstract Background Carbapenem-resistant Acinetobacter baumannii (CRAB) is recognized as a common clinical conditional pathogen with bla OXA−23 gene-mediated multidrug-resistance that is a significant threat to public health safety. …”
Get full text
Article -
4819
Combining systemic inflammation biomarkers with traditional prognostic factors to predict surgical site infections in elderly hip fracture patients: a risk factor analysis and dyna...
Published 2025-01-01“…The Centers for Disease Control and Prevention (CDC) definition of SSI was applied, with SSI identified through medical and pathogen culture records during hospitalization and routine postoperative telephone follow-ups. …”
Get full text
Article -
4820
Evolutionary and functional divergence of Sfx, a plasmid-encoded H-NS homolog, underlies the regulation of IncX plasmid conjugation
Published 2025-02-01“…Therefore, studying the molecular mechanisms underlying conjugation regulation is essential for understanding antimicrobial resistance and pathogen evolution. In this study, we characterized the conjugation regulation of the model IncX plasmid R6K. …”
Get full text
Article