Sero-epidemiological Study of Toxoplasma gondii among Pregnant Women in Akre City by Hogir Mohammed Shukri Saadi, Ahmed Jumaa Ahmed

“…Many previous studies were suggested this pathogen transmits by ingesting of undercooked or raw meat contaminated with the oocytes of this parasite. …”
Get full text

Effect of the host-specific toxin SnTOX3 from Stagonospora nodorum on ethylene signaling pathway regulation and redox-state in common wheat by S. V. Veselova, G. F. Burkhanova, T. V. Nuzhnaya, S. D. Rumyantsev, I. V. Maksimov

“…Our results suggest that NE SnTox3 influences ethylene biosynthesis and signaling, thereby regulating redox metabolism in infected wheat plants as necessary for successful host colonization at the initial phases of infection, which ultimately leads to extensive lesions due to fast pathogen reproduction.…”
Get full text

Systemic Immune-Inflammation Index: A Promising, Non-Invasive Biomarker for Crohn’s Disease Activity and Severity Assessment by Deng Y, Fu T, Gao D, Zhou J, Nie X, Wang F, Yu Q

“…Yu’en Deng,1,2 Ting Fu,1 Dian Gao,3 Jianming Zhou,1 Xinhua Nie,1 Fenfen Wang,1 Qiongfang Yu1 1Department of Gastroenterology and Hepatology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of China; 2Huankui Academy, Jiangxi Medical College, Nanchang University, Nanchang, 330031, People’s Republic of China; 3Department of Pathogen Biology and Immunology, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of ChinaCorrespondence: Qiongfang Yu, Department of Gastroenterology and Hepatology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Minde Road 1, Nanchang, 330006, People’s Republic of China, Email qiongfangyu@yeah.netPurpose: Crohn’s disease (CD) is a chronic inflammatory disorder with periods of exacerbation and remission. …”
Get full text

Identification of Sr genes in new common wheat sources of resistance to stem rust race Ug99 using molecular markers by O. A. Baranova, I. F. Lapochkina, A. V. Anisimova, N. R. Gajnullin, I. V. Iordanskaya, I. Yu. Makarova

“…We used molecular markers associated with effective genes to race Ug99: Sr2, Sr22, Sr24, Sr25, Sr26, Sr32, Sr35, Sr36, Sr39, Sr40, Sr44, Sr47, and with genes that were ineffective but protected wheat cultivars against local pathogen populations: Sr9a, Sr15, Sr17, Sr19 and Sr31. …”
Get full text

Development of an sRNA-mediated conditional knockdown system for Chlamydia trachomatis by Janina Ehses, Kevin Wang, Asha Densi, Cuper Ramirez, Ming Tan, Christine Sütterlin

“…Thus, our sRNA-based approach has broad potential as a conditional knockdown method for studying the function of C. trachomatis genes, including essential genes and genes in an operon.IMPORTANCEWe describe a new method to reduce protein levels of a selected gene in the pathogenic bacterium Chlamydia trachomatis. This approach utilizes an engineered small RNA (sRNA) to inhibit translation of the mRNA for a target gene and produced inducible and reversible protein knockdown. …”
Get full text

Fecal microbiota transplantation modulates jejunal host-microbiota interface in weanling piglets by Shankumar Mooyottu, Muhammed Shafeekh Muyyarikkandy, Farnaz Yousefi, Ganwu Li, Orhan Sahin, Eric Burrough, Joy Scaria, Brett Sponseller, Alejandro Ramirez

“…Prior FMT treatment in the context of ETEC infection indicated a potential protective role, as evidenced by a significant shift in microbial diversity and metabolomic compositions and decreased diarrhea severity even though no effect on pathogen shedding was evident. Conclusions This study underscores the promise of FMT in enhancing jejunal health. …”
Get full text

Isolasi dan Karakterisasi Bakteri Endofit dari Tanaman Binahong dan Katepeng China by Desriani ., Ukhradia Maharaniq Safira P, Maria Bintang, Akhmad Rivai, Puspita Lisdiyanti

“…Methods: The objective of this study was to isolate and to characterize endophytic bacteria from both plants through antibacterial activity test against to three kinds of human pathogenic bacteria (Pseudomonas aeruginosa, Staphylococcus aureus, and Bacillus cereus). …”
Get full text

Prevalence, Risk Factors, and Antimicrobial Resistance Profiles of Thermophilic Campylobacter Species in Humans and Animals in Sub-Saharan Africa: A Systematic Review by Noel Gahamanyi, Leonard E. G. Mboera, Mecky I. Matee, Dieudonné Mutangana, Erick V. G. Komba

“…The colonization of different animal reservoirs by Campylobacter poses an important risk for humans through shedding of the pathogen in livestock waste and contamination of water sources, environment, and food. …”
Get full text

Characteristics of virulence of Puccinia triticina populations and the potential of the Lr24, Lr25, LrSp genes for spring common wheat breeding in the Southern Ural by V. A. Tyunin, E. R. Shreyder, E. I. Gultyaeva, E. L. Shaydayuk

“…Monitoring of pathogen populations is important for successful genetic wheat protection against leaf rust and identification of pathotypes with virulence to the resistance genes used. …”
Get full text

Role of outer membrane vesicles of hypervirulent Klebsiella pneumoniae isolated from bovine uterine discharge in pro-inflammatory dysregulation by A. F. Daham, A. H. Jaber, A. Neamah, H. Al-Karagoly

“…This ability of hvKP OMVs to evade the immune system and modulate host responses contributes significantly to the bacterium’s pathogenicity.…”

Effect of gut microbiota changes on cytokines IL-10 and IL-17 levels in liver transplantation patients by Mohamed Abdel-Raoof Fouda, Mohamed Abdel-Wahhab, Ahmed Esmail Abdelkader, Mohsen El-Sayd Ibrahim, Taher Abozeid Elsheikh, Hisham Mohammad Aldeweik, Nora Elfeky

“…A change in gut microbiota composition was noted, characterized by a rise in potentially pathogenic bacteria such as Enterococci and Enterobacteriaceae (including Escherichia coli and Klebsiella) and a reduction in beneficial bacteria such as Bacteroidetes and Firmicutes. …”
Get full text

Isolation and Identification of Staphylococcus aureus from Milk and Milk Products, Associated Factors for Contamination, and Their Antibiogram in Holeta, Central Ethiopia by Endrias Zewdu Gebremedhin, Addisu Bedashu Ararso, Bizunesh Mideksa Borana, Kebede Abdisa Kelbesa, Nega Desalegn Tadese, Lencho Megersa Marami, Edilu Jorga Sarba

“…Staphylococcus aureus is a pathogenic bacterium-contaminating milk and milk products causing food poisoning primarily due to its enterotoxins. …”
Get full text

ANALYSIS OF GENETIC CHARACTERISTICS OF INFLUENZA VIRUS A/CHICKEN/CHELYABINSK/30/2019 H9N2 ISOLATED IN CHELYABINSK OBLAST by N. G. Zinyakov, Щю S. Osipova, P. B. Akshalova, V. Yu. Sosipatorova, A. V. Andriyasov, D. B. Andreychuk, I. A. Chvala

“…The complete nucleotide genome sequence of the studied pathogen was determined. The comparative analysis of all genomic segments using the GenBank database revealed a close relationship (over 99%) between the A/chicken/Chelyabinsk/30/2019 H9N2 virus and the A/H9 infl uenza virus isolates circulating in Israel in 2006–2012. …”
Get full text

The enriched gut commensal Faeciroseburia intestinalis contributes to the anti-metabolic disorders effects of the Ganoderma meroterpene derivative by Shanshan Qiao, Kai Wang, Chang Liu, Nan Zhou, Li Bao, Jun Wang, Shuangjiang Liu, Hongwei Liu

Get full text

Clinical Role of Epigenetics and Network Analysis in Eye Diseases: A Translational Science Review by Michele Lanza, Giuditta Benincasa, Dario Costa, Claudio Napoli

“…Hypermethylation of H3K4 and hypomethylation of H3K27 at the TGFBIp locus are putative pathogenic mechanisms involved in corneal dystrophies. …”
Get full text

Proteomic profiling of Labeo rohita intestine infected with Edwardsiella tarda: Unveiling the mucosal defense mechanisms, cell adhesion, and cytoskeletal pathways by Nevil Pinto, Mehar Un Nissa, Gowhar Iqbal, Yashwanth BS, Darshan P, Sanjeeva S, Mukunda Goswami

“…Introduction: The pathogenicity mechanism of the intestine induced by the enteric bacteria Edwardsiella tarda is essential for global aquaculture. …”
Get full text

Antimicrobial photodynamic inactivation of Pseudomonas aeruginosa persister cells and biofilms by Mona Mahmoud, Peter Richter, Philipp Arnold, Michael Lebert, Andreas Burkovski

“…Pseudomonas aeruginosa is a hard-to-treat human pathogen for which new antimicrobial agents are urgently needed. …”
Get full text

TERT de novo mutation-associated dyskeratosis congenita and porto-sinusoidal vascular disease: a case report by Ge Yu, Guijie Xin, Xu Liu, Wanyu Li, Chen Shao, Runping Gao

“…A TERT c.2286 + 1G/A mutation in a splicing consensus site was identified in a patient with pulmonary fibrosis. Recently, a pathogenic de novo TERT c.280A > T variant was associated with diffuse lung disease in an infant. …”
Get full text

Improving natural red pigment production by Streptomyces phaeolivaceus strain GH27 for functionalization of textiles with in silico ADME prediction by Gehad H. El Sayed, Mohamed Fadel, Rasha Fouad, Hend M. Ahmed, Ahmed A. Hamed

“…The treatment of cotton, wool, and polyester samples suppressed pathogen growth to differing extents. Polyester had the most important inhibitory effects on Staphylococcus aureus (50.03%) and Bacillus cereus (39.49%). …”
Get full text

Benefits of Virgin Coconut Oil in Diet to Colossoma macropomum (Cuvier, 1818) by Márcia Valéria Silva do Couto, Natalino da Costa Sousa, Higo Andrade Abe, Joel Artur Rodrigues Dias, Carlos Alberto Martins Cordeiro, Peterson Emmanuel Guimarães Paixão, Thays Brito Reis Santos, Fernanda dos Santos Cunha, Juliana Oliveira Meneses, Ricardo Marques Nogueira Filho, Carol Nunes Costa Bomfim, Cláucia Aparecida Honorato, Bruno Trindade Cardoso, Rodrigo Yudi Fujimoto

“…In conclusion, dietary inclusion of 50% virgin coconut in substitution to soybean oil as a lipid source in diets for C. macropomum is recommended to improve the growth performance, body protein, and resistance against pathogenic bacteria Aeromonas hydrophila.…”
Get full text