CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation. by John T Loffredo, Thomas C Friedrich, Enrique J León, Jason J Stephany, Denise S Rodrigues, Sean P Spencer, Alex T Bean, Dominic R Beal, Benjamin J Burwitz, Richard A Rudersdorf, Lyle T Wallace, Shari M Piaskowski, Gemma E May, John Sidney, Emma Gostick, Nancy A Wilson, David A Price, Esper G Kallas, Helen Piontkivska, Austin L Hughes, Alessandro Sette, David I Watkins

“…<h4>Conclusions</h4>Together, our data suggest that Mamu-B*08-restricted CD8+ T cell responses effectively control replication of pathogenic SIV(mac)239. All seven regions encoding Mamu-B*08-restricted CD8+ T cell epitopes also exhibit amino acid replacements typically seen only in the presence of Mamu-B*08, suggesting that the variation we observe is indeed selected by CD8+ T cell responses. …”
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A multi-strain human skin microbiome model provides a testbed for disease modeling by Angela L. Maloney, Tyler Crawford, Jordan Hurlbut, Monica Martinez, Thomas J. Mulhern, Elizabeth L. Wiellette, Else M. Vedula, Vidhya Vijayakumar

“…The skin microbiome plays a critical role at the interface between the human epidermis and the environment, providing colonization resistance against pathogenic strains, training host immunity, and supporting epithelial turnover. …”
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Probiotic Potential of Lactic Acid Starter Cultures Isolated from a Traditional Fermented Sorghum-Millet Beverage by Stellah Byakika, Ivan Muzira Mukisa, Yusuf Byenkya Byaruhanga, Charles Muyanja

“…The cultures were examined for tolerance to acid and bile salts, bile salt hydrolase (BSH) activity, antibiotic susceptibility, biogenic amine production, mucin degradation, hydrophobicity, auto-aggregation, adherence to the ileum, coaggregation, and antimicrobial properties against selected pathogenic species. Lb. rhamnosus yoba 2012, a known probiotic, was the reference. …”
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Deployment of next-generation sequencing approach for variant detection in myocardial infarction: A concise investigation by Desaraju Suresh Bhargav, Nadeem Siddiqui, Bhadra Murthy V, Vijaya Tartte, Vanaja V

“…Conclusion: To ascertain pathogenicity and role in the emergence of MI-related disorders these genes were mapped to online databases. …”
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First two mitochondrial genomes for the order Filobasidiales reveal novel gene rearrangements and intron dynamics of Tremellomycetes by Qiang Li, Zhijie Bao, Ke Tang, Huiyu Feng, Wenying Tu, Lijiao Li, Yunlei Han, Mei Cao, Changsong Zhao

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Comparison of ultraviolet C light and isopropyl alcohol for the disinfection of cellular phones in a paediatric intensive care unit setting by L Thomas, J John, H Lochan

“…A considerable proportion of cellular phones (cell phones) used by healthcare workers (HCWs) have been shown to be contaminated with pathogenic micro-organisms, making these devices reservoirs to infect susceptible patients. …”
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Genetic diversity of barley accessions from East Asian countries in terms of resistance to powdery mildew by R. A. Abdullaev, K. A. Lukina, B. A. Batasheva, O. N. Kovaleva, E. E. Radchenko

“…Golovin ex Speer f. sp. hordei Marchal. The pathogen can overcome a cultivar’s resistance, resulting in significant harvest losses. …”
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Isolation and Antifungal Susceptibility of Candida spp. from Pediatric Patients in Kurdistan of Iraq by Mohammed Salah Bahi, Khattab Ahmed Mustafa Shekhany

“…Candida species are considered the most common opportunistic human fungal pathogen due to the presence of various virulence factors, including its ability to form a biofilm that aids in oral candidiasis. …”
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Molecular subtype of ovarian clear cell carcinoma: an analysis of 80 Chinese patients using the TCGA molecular classification of endometrial cancer by Wei Chen, Lu Yan, Qin Li, Shuling Zhou, Ting Hou, Huijuan Yang, Shuang Ye

“…Results The most common mutated genes were ARID1A (49%) and PIK3CA (48%). No pathogenic POLE mutations were detected. MSI-high (MSI-H) tumours were observed in 5 (6.3%) patients. …”
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Assessments of Antibacterial Effects of Aqueous-Ethanolic Extracts of Sida rhombifolia’s Aerial Part by Demeke Debalke, Mastewal Birhan, Amebaye Kinubeh, Muluken Yayeh

“…In addition to this, the antibacterial activity of the plant extract was evaluated on five pathogenic bacteria species using agar well diffusion method at different concentrations of plant extracts. …”
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Comprehensive Metabolomic Profiling in Adults with X-Linked Hypophosphatemia: A Case-Control Study by Luis Carlos López-Romero, José Jesús Broseta, Marta Roca-Marugán, Noemí Máñez Ramírez, Julio Hernández-Jaras

“…These findings enhance understanding of potential pathogenic mechanisms and offer a metabolic basis for further in-depth investigations into XLH.…”
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Effects of different doses of skt-b vibrio probiotic bacteria addition on survival and growth rate of tiger shrimp (Penaeus monodon) larva by . Widanarni, M.A. Lidaenni, Dinamella Wahjuningrum

“…Vibrio SKT-b is one of the probiotic bacteria candidates that could suppressed the growth of pathogenic bacteria Vibrio harveyi and could increase survival rate of tiger shrimp larva. …”
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Effect of Zbtb33 gene knockout and bacterial lipopolysaccharide on home cage behavior in mice by N. V. Khotskin, I. E. Sorokin, E. A. Kulikova, A. V.  Kulikov

“…All animals were 11 weeks old, weighed 26 ± 1 g and had SPF (specific pathogen free) status throughout the experiment. The animals of each genotype were divided into three weighted groups of 8 animals each. …”
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Colchicine Does Not Reduce Abdominal Aortic Aneurysm Growth in a Mouse Model by James Phie, Shivshankar Thanigaimani, Pacific Huynh, Raghuveeran Anbalagan, Corey S. Moran, Robert Kinobe, Joseph V. Moxon, Matt A. Field, Smriti M. Krishna, Jonathan Golledge

“…The nacht domain, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome is upregulated in human abdominal aortic aneurysm (AAA), but its pathogenic role is unclear. The aims of this study were firstly to examine whether the inflammasome was upregulated in a mouse model of AAA and secondly to test whether the inflammasome inhibitor colchicine limited AAA growth. …”
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Molecular mechanisms and therapeutic strategies of Naegleria fowleri Carter (1970): a review of the fatal brain-eating amoeba by N. Datta

“…This review provides a comprehensive overview of the current state of knowledge on N. fowleri, its pathogenic molecular mechanisms, and the biological processes involved in its infection, as well as the challenges and perspectives for future research.…”
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Antifungal Activity of Gelatin-Tapioca Starch Film and Coating Containing Copper Nanoparticles against Colletotrichum gloeosporioides Causing Anthracnose by Vinh Tien Nguyen, My-Sam Dang-Thi, Khanh Son Trinh

“…This study aimed to fabricate a nontoxic coating containing copper nanoparticles (CuNPs) to protect fruits from pathogenic Colletotrichum gloeosporioides causing anthracnose on several tropical fruits. …”
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High Seropositivity of Brucella melitensis Antibodies among Pregnant Women Attending Health Care Facilities in Mwanza, Tanzania: A Cross-Sectional Study by Helmut A. Nyawale, Michael Simchimba, Joseph Mlekwa, Fridolin Mujuni, Elieza Chibwe, Prosper Shayo, Elifuraha B. Mngumi, Khadija S. Majid, Mtebe Majigo, Stephen E. Mshana, Mariam M. Mirambo

“…Brucella melitensis (B. melitensis), the most pathogenic species is responsible for several pregnancy adverse outcomes in both humans and animals. …”
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Escherichia coli in septic arthritis: prevalence and antibiotics susceptibility patterns by Masroora Ali Khan, Muhammad Kamran Taj, Zahid Khan, Imran Taj, Muhammad Naeem, Saima Azam

“…Sequence analysis using the Basic Local Alignment Search Tool found high similarity with pathogenic E. coli from Egypt and China. The identified E. coli strain showed significant resistance to common antibiotics: amoxicillin, amoxicillin-clavulanate, ceftriaxone, sulfamethoxazole/trimethoprim, gentamicin, tetracycline, and erythromycin. …”
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Pathogenetic Substantiation of the Therapeutic Impact on Microbiota in Irritable Bowel Syndrome by Yu. O. Shulpekova, G. H. Babaeva, V. Yu. Rusyaev

“…Reduced microbial diversity increases susceptibility to intestinal infections and parasitoses, including those caused by protozoa conditionally pathogenic for adults, such as Blastocystis hominis hominis, Dientamoeba fragilis, Giardia lamblia. …”
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The Effect of Banana Bacteria Wilt on The Socio-Economic Welfare of Farmers in Ruhinda Sub-County Rukungiri District . by Tayebwa, Rameka

“…The highest number of respondents mentioned source of mulch for maintaining and improving soil fertility, the lowest number of respondents mentioned that the disease has led to increased poverty among households and the study continued on possible measures to control banana bacteria wilt in Ruhinda sub-county Rukungiri district, the highest number of respondents mentioned heating garden tools such as hoes, machete, knives and slashers over a fire until the metal is too hot to touch is also effective in killing the bacteria, the lowest number of respondents talked of timely removal of male buds with a forked stick is important in where insect vector that visit the diseased flower parts carry the pathogen. The study recommended that there should be quarantine enforcement by the government agencies to prevent spread of banana bacteria wilt to non-infected areas, there should be policies on the use of clean planting materials and regular inspection/screening for the approved banana nurseries to dispense banana bacteria wilt disease free materials and there should be production of free banana bacteria wilt such as banana tissue culture, train and encourage more banana nurseries producers/tissue culture hardening nurseries to avail clean banana planting materials.…”
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