High Doses of Halotolerant Gut-Indigenous Lactobacillus plantarum Reduce Cultivable Lactobacilli in Newborn Calves without Increasing Its Species Abundance by Alexander Rodriguez-Palacios, Henry R. Staempfli, J. Scott Weese

“…For the first time, a halotolerant strain of L. plantarum with inhibitory activity against a human pathogen has the ability to inhibit other lactobacilli in vivo without changing its species abundance, causing transintestinal translocation, or inducing clinical disease. …”
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Fn14 Deficiency Ameliorates Anti-dsDNA IgG-Induced Glomerular Damage in SCID Mice by Jiawen Wu, Xiaoyun Min, Li Wang, Jie Yang, Ping Wang, Xingyin Liu, Yumin Xia

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Meta-Analysis of Expression Profiling Data Indicates Need for Combinatorial Biomarkers in Pediatric Ulcerative Colitis by Xinxiu Li, Eun Jung Lee, Danuta R. Gawel, Sandra Lilja, Samuel Schäfer, Huan Zhang, Mikael Benson

“…The most activated predicted upstream regulators included TNF, which is known to have a key pathogenic and therapeutic role in pediatric UC. Despite this, the expression levels of TNF were increased in neither colonic biopsies nor WBC. …”
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Serotyping and antimicrobial resistance of Actinobacillus pleuropneumoniae isolates from fattening pigs in Poland from 2019 to 2024 by Przyborowska Paulina, Tobolski Dawid

“…Abstract Background Actinobacillus pleuropneumoniae is a prevalent respiratory pathogen causing substantial economic losses in swine production worldwide. …”
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Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production by Parnian Arafi, Sujan Devkota, Emily Williams, Masato Maesako, Michael S Wolfe

“…These findings provide further evidence that FAD mutations lead to stalled and stabilized γ-secretase enzyme-substrate and/or enzyme-intermediate complexes and are consistent with the stalled process rather than the products of γ-secretase proteolysis as the pathogenic trigger.…”
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Phenotypic and genotypic screening of multidrug resistant Klebsiella pneumoniae isolated from ready to eat street food in Tanta, Egypt by Hadeer M. Bedair, Mohamed Emara, Shima Mahmoud Ali, Tamer M. Samir, Mahmoud A.F. Khalil

“…Klebsiella pneumoniae has become a dangerous foodborne-pathogen worldwide due to its virulence and resistance profile. …”
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Comprehensive analysis of the succinylome in Vero cells infected with peste des petits ruminants virus Nigeria 75/1 vaccine strain by Xuelian Meng, Xueliang Zhu, Xiangwei Wang, Rui Zhang, Zhidong Zhang, Yuefeng Sun

“…Succinylation is a newly identified and conserved modification and plays an important role in host cell response to pathogen infection. However, the extent and function of succinylation in Vero cells during PPRV infection remains unknown. …”
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Immune-mediated mechanisms in acute osteofascial compartment syndrome: insights from multi-omics analysis by Qinzhen Lu, He Ling, Yonghui Lao, Junjie Liu, Wei Su, Zhao Huang

“…Hence, there is an urgent need for research elucidating AOCS's pathogenic mechanism and exploring novel treatments. …”
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Prebreeding studies of leaf rust resistant <i>Triticum aestivum/T. timopheevii</i> line L624 by S. N. Sibikeev, I. G. Adonina, A. E. Druzhin, O. A. Baranova

“…Triticum timopheevii Zhuk. attracts the attention of bread wheat breeders with its high immunity to the leaf rust pathogen. However, introgressions from this species in Triticum aestivum L. are little used in practical breeding. …”
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Comparison of chromogenic and cysteine lactose electrolyte deficient agar for identification of uropathogens in Gujarat, India by Nisha Vadivelu, Rashmika D. Parmar, Hitesh Shingala, Krunal D. Mehta

“…The performance of chromogenic UTI agar was assessed for pathogen identification, detection of polymicrobial infections, time to results, and cost-effectiveness. …”
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Physiological and transcriptomic analysis of the effect of overexpression of the NTPIP2;4 gene on drought tolerance in tobacco by Xu Luo, Yuanshuai Shi, Jie Tan, Tao Long, Juntao Song, Yang Liu

“…The DEGs were enriched mainly in the plant MAPK signaling pathway, the plant hormone signal transduction pathway, amino sugar and nucleotide sugar metabolism, starch and sucrose metabolism and plant-pathogen interaction pathways. We also investigated the drought pathway of MAPK pathway and the auxin pathway mechanism of plant hormone signal transduction pathway, and found that the transcript levels of the genes of the relevant pathways changed, and hypothesized that NtPIP2;4 might regulate the drought resistance of plants through the expression of the relevant genes induced by auxin. …”
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Avian influenza overview September–December 2024 by European Food Safety Authority, European Centre for Disease Prevention and Control, European Union Reference Laboratory for Avian Influenza, Leonidas Alexakis, Hubert Buczkowski, Mariette Ducatez, Alice Fusaro, Jose L. Gonzales, Thijs Kuiken, Karl Ståhl, Christoph Staubach, Olov Svartström, Calogero Terregino, Katriina Willgert, Miguel Melo, Lisa Kohnle

“…Abstract Between 21 September and 6 December 2024, 657 highly pathogenic avian influenza (HPAI) A(H5N1) and A(H5N5) virus detections were reported in domestic (341) and wild (316) birds across 27 countries in Europe. …”
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Analyses of urogenital Mycoplasma hominis and Ureaplasma urealyticum infections and drug sensitivity in 296 patients by CHEN Junwei, HUANG Sheng, QIU Wei, XIAO Yupeng

“…[Conclusions] Females are more likely to have urogenital tract mycoplasma infections than males, and Uu is the main pathogen. The three types of infections are sensitive to doxycycline and minocycline. …”
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THE MORPHOGENIC POTENTIAL OF SIBERIAN POTATO CULTIVARS IN TISSUE CULTURES by S. M. Ibragimova, A. V. Romanova, G. Kh. Myzgina, A. V. Kochetov

“…It is prone to several pathogenic fungi, viruses, and bacteria, which cause severe economic loss every year. …”
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The periplasmic protein HslJ is the first-line of defense against oxidative stress in Acinetobacter baumannii by Daniela Scribano, Martina Pasqua, Dolores Limongi, Lucia Nencioni, Anna Teresa Palamara, Cecilia Ambrosi

“…Conclusions This comprehensive understanding of HslJ multifaceted role not only enriches our knowledge of A. baumannii stress response mechanisms but also provides valuable insights for developing targeted strategies to eradicate this deadly resilient pathogen in healthcare settings.…”
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Gut colonization of Bacteroides plebeius suppresses colitis-associated colon cancer development by Hung-Lin Chen, Po-Yuan Hu, Chang-Shan Chen, Wei-Han Lin, Daniel K. Hsu, Fu-Tong Liu, Tzu-Ching Meng

“…We also showed that colonization of B. plebeius suppressed the colon tumor development induced by azoxymethane/dextran sulfate sodium in specific-pathogen-free mice, coinciding with a reduced abundance of Muribaculaceae sp., Closteridale sp., and Bilophila sp. …”
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Global knowledge gaps in acute febrile illness etiologic investigations: A scoping review. by Chulwoo Rhee, Grishma A Kharod, Nicolas Schaad, Nathan W Furukawa, Neil M Vora, David D Blaney, John A Crump, Kevin R Clarke

“…<h4>Conclusions</h4>Wider implementation of standardized AFI reporting methods, with multi-pathogen disease detection, could improve comparability of study findings, knowledge of the range of AFI etiologies, and their contributions to the global AFI burden. …”
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Genetic analysis of scab disease resistance in common bean (Phaseolus vulgaris) varieties using GWAS and functional genomics approaches by Shadrack Odikara Oriama, Benard W. Kulohoma, Evans Nyaboga, Y. O. Masheti, Reuben Otsyula

“…Abstract Introduction Scab is a fungal disease of common beans caused by the pathogen Elsinoë phaseoli. The disease results in major economic losses on common beans, and there are efforts to develop integrated pest management strategies to control the disease. …”
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Study of Antibacterial Activity of Root Bark, Leaves, and Pericarp Extracts of Diploknema butyracea and Evaluation of Prospective Antioxidant Activity by Alisha Karki Chhetry, Subhila Dhakal, Lalita Chaudhary, Khimdhoj Karki, Ram Bahadur Khadka, Gautam Prasad Chaudhary, Tonking Bastola, Amrit Poudel, Pramod Aryal, Jitendra Pandey

“…Overall, our study showed that the root bark, pericarp, and leaves extract of D. butyracea evinced prominent antibacterial properties against various pathogenic bacterial strains.…”
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Bacterial Profile among Patients with Suspected Bloodstream Infections in Ethiopia: A Systematic Review and Meta-Analysis by Birhan Alemnew, Habtamu Biazin, Asmamaw Demis, Melese Abate Reta

“…Furthermore, we found a remarkable variation in the pathogen distribution across the study setting.…”
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