Physiological and intestinal microbiota responses of sea cucumber Apostichopus japonicus to various stress and signatures of intestinal microbiota dysbiosis by Liang Cui, Yumeng Xie, Kai Luo, Mingyang Wang, Longzhen Liu, Longzhen Liu, Changlin Li, Xiangli Tian

“…The ratios of Bacteroidota: Proteobacteria (B: P) and Firmicutes: Proteobacteria (F: P) declined markedly compared to the control. Potentially pathogenic bacteria of Shewanellaceae, Vibrionaceae, and Moraxellaceae significantly increased under crowding, ammonium, and nitrite stress, respectively, whereas beneficial microbes of Achromobacter and Rhodobacteraceae were, respectively, enriched under hypoosmotic and starvation stresses. …”
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Orally administered live BCG and heat-inactivated Mycobacterium bovis protect bison against experimental bovine tuberculosis by Nirajan Niroula, Priya Ghodasara, Nelson Marreros, Bailey Fuller, Haley Sanderson, Slim Zriba, Stew Walker, Todd K. Shury, Jeffrey M. Chen

“…Abstract Bovine tuberculosis (BTB) is an infectious disease of livestock and wildlife species that is caused by pathogenic members of the Mycobacterium tuberculosis complex such as Mycobacterium bovis. …”
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Gene Expression Pattern and Regulatory Network of α-Toxin Treatment in Bombyx mori by Tieshan Feng, Ping Lin, Jiao Gong, Dong Cheng, Xi Yang, Quan Zhang, Tingcai Cheng

“…Bacillus bombyseptieus is a pathogen of Bombyx mori; it can cause bacterial septicemia in silkworm. …”
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Clinical assessment and transcriptome analysis of host immune responses in a vaccination-challenge study using a glycoprotein G deletion mutant vaccine strain of infectious laryngo... by Gayathri Gopakumar, Mauricio J. C. Coppo, Mauricio J. C. Coppo, Andrés Diaz-Méndez, Carol A. Hartley, Joanne M. Devlin

“…In the current study, the transcriptome of peripheral blood mononuclear cells (PBMCs) of the ΔgG-ILTV-vaccinated group of specific-pathogen-free chickens were compared to those of the nonvaccinated group at 7 days post-vaccination. …”
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Application of indigenous zinc-solubilizing bacteria in biofertilizers to enhance zinc nutrition of rice grains in inceptisols paddy fields by E. Pratiwi, P. Lestari, Y. Nugraha, W. Hartatik, Z. Susanti, I.G.M. Subiksa, A. Kasno, T.A. Adriany, Y.S. Fatma, A.F. Nababan, A.A. Rivaie

“…The seedlings were prepared individually for each rice variety, with a comparison made between those treated with the biofertilizer and those that were not.FINDINGS: The study found that the consortium of indigenous non-pathogenic zinc-solubilizing bacteria significantly increased the yield of rice varieties by about 5.6 percent and zinc content in grains by 16.3 percent. …”
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Bioactive phytochemical compounds characterization, anti-oxidant and anti-microbial activity of the methanol and acetonitrile leaf extracts of Pithecellobium dulce by M. Kiranmayee, K. Riazunnisa

“…Purpose: The aim of this investigation is to demonstrate the phytochemical profiling of methanol and acetonitrile leaf extracts of P. dulce and evaluate their antioxidant activity and antibacterial potential against pathogenic bacteria. Materials and methods: The methanol and acetonitrile extracts of P. dulce leaf were extracted and characterized by using GCMS– and FTIR. …”
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Relationship of Autophagic Dysfunction With the Quality of Life and Sleep, Depression and Disease Severity in Patients With Restless Legs Syndrome by Esen Çiçekli, Hamza Malik Okuyan, Canan Birimoğlu Okuyan, Şeyda Öznur Ayçiçek, Dilcan Kotan

“…Autophagy is essential for the maintenance of healthy cellular physiology, cell viability, and defense against pathogenic conditions. However, there is no study investigating the possible role of autophagy‐related proteins (ATGs) in RLS patients. …”
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In vitro high-throughput screening of the antimicrobial activity of different compounds against Xylella fastidiosa subsp. pauca by Carmine Del Grosso, Luca Grandi, Tommaso Lombardi, Giusy D’Attoma, Nicolas Schmitt, Vito Rocco De Michele, Maria Saponari

“…Among the different European isolates, those of the subspecies pauca have been ranked as highly pathogenic, being the causal agents of the olive quick decline decimating olive trees in southern Italy. …”
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Bio-protective solutions for carrot spoilage: exploring the antifungal properties of ginger, garlic, onion, and Moringa by Eugenia Njoku, Florence Mbaoji, Justus Nweze, Bonaventure Echezona, Kayode Baiyeri

“…Purpose: To address postharvest losses in the carrot supply chain caused by pathogenic fungi, this study evaluates the antifungal potential of ethanol extracts from Allium cepa, Zingiber officinale, Allium sativum, and Moringa oleifera against carrot spoilage fungi, including Aspergillus niger, Aspergillus fumigatus, Aspergillus flavus, Fusarium oxysporum, and Fusarium solani. …”
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Factors Related to Personal Hygiene of Traditional Jamu Handler in Bantul District, Indonesia by Dyah Suryani, Atika Rahma Indriani, Suyitno Suyitno

“… Background: Foodborne disease is the contamination of pathogenic bacteria that multiply in drinks. Traditional jamu handlers, people who process conventional jamu, need to implement and understand the importance of personal hygiene to avoid bacterial contamination. …”
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Empiric antibiotic therapy resistance and mortality in emergency department patients with bloodstream infection: a retrospective cohort study by Leonhard M. von Beck, Gabriella Anna Rapszky, Veronika E. Kiss, Szilard Sandor, Szabolcs Gaal-Marschal, Tamas Berenyi, Csaba Varga, Bank G. Fenyves

“…The association of mortality with empiric emergency department-initiated antibiotic adequacy is pathogen-dependent.…”
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Identification and prioritization of novel therapeutic candidates against glutamate racemase from Klebsiella pneumoniae. by Ankit Kumar, Farah Anjum, Md Imtaiyaz Hassan, Anas Shamsi, Rashmi Prabha Singh

“…This study could significantly help the medical fraternity in the treatment of infections caused by this multidrug-resistant pathogen.…”
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Epigenetic Biomarkers and the Wnt/β-Catenin Pathway in Opisthorchis viverrini-associated Cholangiocarcinoma: A Scoping Review on Therapeutic Opportunities. by Alok Kafle, Sutas Suttiprapa, Mubarak Muhammad, Jan Clyden B Tenorio, Roshan Kumar Mahato, Norhidayu Sahimin, Shih Keng Loong

“…Considering the distinct etiological agent, pathogenic mechanisms, and pathological manifestations, epigenetic research plays a pivotal role in uncovering markers and potential targets related to the cancer-promoting and morbidity-inducing liver fluke parasite prevalent in the Great Mekong Subregion (GMS). …”
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Understanding Autoimmune Mechanisms in Multiple Sclerosis Using Gene Expression Microarrays: Treatment Effect and Cytokine-related Pathways by A. Achiron, M. Gurevich, D. Magalashvili, I. Kishner, M. Dolev, M. Mandel

“…Our results indicate that cytokine-associated genes are involved in various pathogenic pathways in MS and also related to immunomodulatory treatment effects.…”
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Gene Polymorphism of Antigen B Subunit 2 and Pathogenesis of Cystic Echinococcosis in Murine Model by Hadi M. Alsakee, Hussein M. Abdulla, Reshna K. Albarzanji

“….: AY569356.1) has no significant impact on the pathogenicity of the CE in murine model. To upgrade the diagnostic sensitivity rates of the immunological techniques, a mixture of native hydatid antigens containing AgB is recommended to be used in the ser-diagnosis of this infection. …”
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Antimicrobial and antiproliferative activity of biosynthesized manganese nanocomposite with amide derivative originated by endophytic Aspergillus terreus by Nashwa El-Gazzar, Reem Farouk, Nervana S. Diab, Gamal Rabie, Basel Sitohy

“…Conclusion The use of HDOCOX, either alone or in combination with MnNPs, is a potential candidate for inhibiting pathogenic microbes and the development of an anticancer drug pipeline.…”
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Polymorphism of the mannose-binding lectin gene in the Arctic indigenous populations of the Russian Federation by S. Yu. Tereshchenko, M. V. Smolnikova

“…Mannose-binding lectin (MBL) is a pattern recognizing acute-phase protein of the innate immunity system actively involved in the elimination of a wide range of pathogenic microorganisms by activating the lectin pathway of the complement system. …”
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Clinical, biochemical and molecular characteristics of classic homocystinuria in Saudi Arabia and the impact of newborn screening on prevention of the complications: A tertiary cen... by Ahmed Sarar Mohamed, Talal AlAnzi, Amal Alhashem, Hadeel Alrukban, Fahad Al Harbi, Sarar Mohamed

“…Seven previously reported variants were detected in this cohort and one novel variant was found in three patients (c.828+2‐828+ 3 delins ACACTTGCATCC, p.?). The known pathogenic variant (c.969G>A, p. (Trp323*)) was seen in most of the patients, with all of them coming from one tribe. …”
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Prevalence of the polymorphic H-ficolin (FCN3) genes and mannosebinding lectin-associated serine protease-2 (MASP2) in indigenous populations from the Russian Arctic regions by M. V. Smolnikova, S. Yu. Tereshchenko

“…Lectins, being the main proteins of the lectin pathway activating the complement system, are encoded by polymorphic genes, wherein point mutations cause the protein conformation and expression to change, which turns out to have an effect on the functionality and ability to respond to the pathogen. In the current study, largescale data on the population genotype distribution of the genes for H-ficolin FCN3 rs28357092 and mannose-binding lectin-associated serine protease MASP2 rs72550870 among the indigenous peoples of the Russian Arctic regions (Nenets, Dolgans and Nganasans, a mixed population and Russians: a total sample was about 1000 newborns) have been obtained for the first time. …”
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Real World Evaluation of Next-Day Molecular Respiratory Infectious Disease Testing on Healthcare Resource Utilization and Costs by French AJ, Fragala MS, Evans AS, Upadhyay P, Goldberg SE, Reddy J

“…Andrea J French, Maren S Fragala, Azia S Evans, Pallavi Upadhyay, Steven E Goldberg, Jairus Reddy HealthTrackRx, Denton, TX, USACorrespondence: Maren S Fragala, HealthTrackRx, 1500 Interstate 35W, Denton, TX, 76207, USA, Email Maren.Fragala@HealthTrackrx.comPurpose: Advancements in pathogen identification by diagnostic testing may improve patient outcomes. …”
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