Infectious bursal disease virus: identification of the novel genetic group and reassortant viruses by L. O. Scherbakova, Ye. V. Ovchinnikova, T. N. Zybina, S. N. Kolosov, N. G. Zinyakov, Z. B. Nikonova, D. B. Andreychuk, I. A. Chvala

“…Detection of different combinations of IBDV genome segments is indicative of the fact that the heterogeneous virus population circulates on the poultry farms. Pathogenicity studies of the three IBDV isolates showed that the most virulent was an isolate having two genome segments characteristic of the highly virulent virus. …”
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Antiviral activity of natural compounds extracted from Mediterranean medicinal plants against SARS-CoV-2 by Stephanie Ghio, Jean-Pierre Brincat, Yuksel Cetin, Frederick Lia

“…The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to a pandemic with devastating outcomes, and hence, there is a global need to search for small-molecule inhibitors that can act against this viral pathogen. This review highlights studies that have investigated the antiviral activities of spices and Mediterranean herbs, as well as their mechanism of action against SARS-CoV-2. …”
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Prevalence and Antimicrobial Resistance of Escherichia coli in Chicken Meat and Edible Poultry Organs Collected from Retail Shops and Supermarkets of North Western Province in Sri... by R. A. S. S. Ranasinghe, D. A. Satharasinghe, P. S Anwarama, P. M. S. D. K. Parakatawella, L. J. P. A. P. Jayasooriya, R. M. S. B. K. Ranasinghe, R. P. V. J. Rajapakse, J. T. Y. Huat, Y. Rukayadi, Y. Nakaguchi, M. Nishibuchi, S. Radu, J. M. K. J. K. Premarathne

“…Shiga toxin-producing strains of E. coli STECs are responsible for most food-related E. coli infections. Pathogenic E. coli transmits to human bodies due to the consumption of contaminated, raw, or undercooked food. …”
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Gene Expression Profiling of IL-17A-Treated Synovial Fibroblasts from the Human Temporomandibular Joint by Toshio Hattori, Naomi Ogura, Miwa Akutsu, Mutsumi Kawashima, Suguru Watanabe, Ko Ito, Toshirou Kondoh

“…Synovial fibroblasts contribute to the inflammatory temporomandibular joint under pathogenic stimuli. Synovial fibroblasts and T cells participate in the perpetuation of joint inflammation in a mutual activation feedback, via secretion of cytokines and chemokines that stimulate each other. …”
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Circulating Th17, Th22, and Th1 Cells Are Elevated in the Guillain-Barré Syndrome and Downregulated by IVIg Treatments by Shujuan Li, Tao Jin, Hong-Liang Zhang, Hong Yu, Fanhua Meng, Hernan Concha Quezada, Jie Zhu

“…However, some changes in GBS could not be explained completely by Th1 cells pathogenic role. Recently, Th17 cells have been identified and can mediate tissue inflammation and autoimmune response. …”
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Mature Tiankengs are biodiversity hotspots of soil microorganisms in the karst region by Junbo Yang, Xiaohui Wang, Keyi Wang, Danjuan Zeng, Ling Mo, Shuai Li, Baozhu Fang, Bhagwan Rekadwad, Wenjun Li, Gaozhong Pu

“…The microbial functions of human pathogenic, aromatic compounds and plastic degradation associated were higher in Tiankeng than in the outside. …”
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Selenium-enriched and ordinary green tea extracts prevent high blood pressure and alter gut microbiota composition of hypertensive rats caused by high-salt diet by Meirong Wu, Xiaobin Wu, Jiangxiong Zhu, Fanglan Li, Xinlin Wei, Yuanfeng Wang

“…Moreover, GT and Se-GT supplementations increased the abundance of beneficial bacteria and reduced the abundance of harmful or conditional pathogenic bacteria. More specifically, GT intake specifically and significantly enriched the relative abundance of Paraprevotella and Bacteroides, whereas Se-GT was characterized by specific and significant enrichment for Allobaculum and Bifidobacterium. …”
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Identification of HNF4A Mutation p.T130I and HNF1A Mutations p.I27L and p.S487N in a Han Chinese Family with Early-Onset Maternally Inherited Type 2 Diabetes by Ying Yang, Tai-Cheng Zhou, Yong-Ying Liu, Xiao Li, Wen-Xue Wang, David M. Irwin, Ya-Ping Zhang

“…We demonstrated that mutation p.T130I in HNF4A was pathogenic as were the predicted polymorphisms p.I27L and p.S487N in HNF1A by genetic and functional analysis. …”
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First evidence of the effectiveness of a field application of RNAi technology in reducing infestation of the mite Varroa destructor in the western honey bee (Apis mellifera) by Francesca Bortolin, Emanuele Rigato, Sergio Perandin, Anna Granato, Laura Zulian, Caterina Millino, Beniamina Pacchioni, Franco Mutinelli, Giuseppe Fusco

“…Traditional control methods, such as chemical pesticides, although quick and temporarily effective, leave residues in hive products, harming bees and operators’ health, while promoting pathogen resistance and spread. As a sustainable alternative, RNA interference (RNAi) technology has shown great potential for honey bee pest control in laboratory assays, but evidence of effectiveness in the field has been lacking. …”
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Clinical characteristics of female Fabry disease patients with hypertrophic cardiomyopathy with mid-ventricular obstruction by Natsuko Inagaki, Yasuyoshi Takei, Tsuguhisa Hatano, Yasuyuki Takada, Yoshinao Yazaki, Hisanori Kosuge, Masatake Kobayashi, Shinji Suzuki, Tomohiro Umezu, Masahiko Kuroda, Kazuhiro Satomi, Takeharu Hayashi

“…We performed a causative gene analysis in patients with a rare subtype of HCM, HCM with mid-ventricular obstruction (HCM-MVO), and identified four patients with different pathogenic variants of GLA, which were clinically confirmed as FD. …”
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Negative Effects of High Glucose Exposure in Human Gonadotropin-Releasing Hormone Neurons by Annamaria Morelli, Paolo Comeglio, Erica Sarchielli, Ilaria Cellai, Linda Vignozzi, Gabriella B. Vannelli, Mario Maggi

“…In conclusion, our findings demonstrate a deleterious direct contribution of high glucose on human GnRH neurons, thus providing new insights into pathogenic mechanisms linking metabolic disorders to reproductive dysfunctions.…”
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Exploring <i>RNF213</i> in Ischemic Stroke and Moyamoya Disease: From Cellular Models to Clinical Insights by Benjamin Y. Q. Tan, Charlene H. P. Kok, Megan B. J. Ng, Shaun Loong, Eric Jou, Leonard L. L. Yeo, Weiping Han, Christopher D. Anderson, Chiea Chuen Khor, Poh San Lai

“…By integrating evidence across disciplines, this review identifies critical knowledge gaps, including the biological pathways underlying <i>RNF213</i>’s pathogenicity. These insights lay the groundwork for future research and underscore the potential of <i>RNF213</i> in driving personalized approaches to cerebrovascular disease management.…”
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Predatory bacteria can intensify lung-injury in a multidrug-resistant Acinetobacter baumannii pneumonia model in rat by Zeinab Mohsenipour, Farzaneh Kianian, Behnaz Jahanbin, Hamid Reza Abtahi, Tooba Ghazanfari, Maryam Edalatifard, Saeid Amanpour, Mikael Skurnik, Parya Arazi, Mohammad Mehdi Feizabadi, Mohammad Mehdi Feizabadi

“…However, treatment with predatory bacteria not only failed to reduce the pathogen load in the lungs to the same extent as the antibiotic treatment group, but also induced acute pulmonary and systemic inflammatory responses. …”
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Effect of Time and Temperature on the Detection of PRRSV RNA and Endogenous Internal Sample Control in Porcine Tongue Fluids by Isadora F. Machado, Onyekachukwu H. Osemeke, Kent Doolittle, Cesar A. A. Moura, Lucina Galina Pantoja, Giovani Trevisan, Phillip Gauger, Daniel C. L. Linhares

“…Population-based sampling has improved pathogen monitoring in the US swine industry by increasing sensitivity while reducing costs. …”
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Occurrence of macrolides resistance in Legionella pneumophila ST188: Results of the Belgian epidemiology and resistome investigation of clinical isolates by Charlotte Michel, Fedoua Echahidi, Geraldine De Muylder, Max Sewell, Ian Boostrom, Olivier Denis, Owen B. Spiller, Denis Pierard

“…Although Legionella pneumophila is known as pathogenic, systematic investigations into antibiotic resistance are scarce, and reports of resistance in isolates are recently emerging. …”
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Analysis of somatic piRNAs in the malaria mosquito Anopheles coluzzii reveals atypical classes of genic small RNAs by Sergei Funikov, Alexander Rezvykh, Natalia Akulenko, Jiangtao Liang, Igor V. Sharakhov, Alla Kalmykova

“…In diverse arthropod species, including the pathogen vectors mosquitoes, the piRNA pathway is also active in nongonadal somatic tissues, where its targets and functions are less clear. …”
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Comparative Biotypic and Phylogenetic Profiles of Escherichia coli Isolated from Resident Stool and Lagoon in Fresco (Côte d’Ivoire) by Nadége Kouadio-Ngbesso, Koua Atobla, Paul Yao Attien, Mireille Kouame-Sina, René Ahua Koffi, Antoinette Ama Adingra, Adjehi Dadié

“…A close relationship was found between water and human strains, and the presence of commensal and extraintestinal pathogenic E. coli in all samples could represent a potential reservoir of extraintestinal infections for resident populations.…”
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Baicalin: a potential therapeutic agent for acute kidney injury and renal fibrosis by Xiaoming Li, Xiaoming Li, Rui Xu, Rui Xu, Dan Zhang, Ji Cai, Ji Cai, He Zhou, He Zhou, Tao Song, Tao Song, Xianyao Wang, Xianyao Wang, Qinghong Kong, Liujin Li, Zhaohui Liu, Zhixu He, Zhengzhen Tang, Jun Tan, Jidong Zhang, Jidong Zhang, Jidong Zhang

“…It is characterized by a fast and prolonged loss in renal function arising from numerous etiologies and pathogenic pathways. Renal fibrosis, defined as the excessive accumulation of collagen and proliferation of fibroblasts within renal tissues, contributes to the structural damage and functional decline of the kidneys, playing a pivotal role in the advancement of Chronic Kidney Disease (CKD). …”
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Identification and Characterization of the <i>ROP GTPase</i> Gene Family in Strawberry and the Positive Role of <i>FveROP4</i> in Fruit Resistance to Gray Mold by Shuai Zhao, Baode Zhu, Zhijun Zou, Yushan Zhai, Sufeng Liao, Ming Xu, Kunyang Li, Nasir Mehmood, Xiong Liao

“…By conducting transient overexpression experiments in strawberry fruits challenged with the gray mold pathogen <i>Botrytis cinerea</i>, we investigated the impact of the <i>FveROP4</i> gene on disease resistance. …”
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Coupling of an Au@AgPt nanozyme array with an micrococcal nuclease-specific responsiveness strategy for colorimetric/SERS sensing of Staphylococcus aureus in patients with sepsis by Xueqin Huang, Yingqi Yang, Hanlin Zhou, Liping Hu, Annan Yang, Hua Jin, Biying Zheng, Jiang Pi, Jun Xu, Pinghua Sun, Huai-Hong Cai, Xujing Liang, Bin Pan, Junxia Zheng, Haibo Zhou

“…Rapid and ultrasensitive detection of pathogen-associated biomarkers is vital for the early diagnosis and therapy of bacterial infections. …”
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