Leaf and tuber resistance to <I>Phytophthora infestans</I> and relationship between these traits in wild potato species by N. M. Zoteyeva, E. A. Porokhovinova, D. A. Fateev, N. A. Chalaya

“…Phytophthora infestans (Mont.) de Bary is a well-known serious pathogen that affects a wide range of currently grown potato cultivars. …”
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Molecular study of blaCTX-M profile among uropathogenic Proteus mirabilis isolates by Kadhim Jwad Jamin, Hussein O. M. Al-Dahmosi, Sura Ihsan Abed Jabuk

“…Infection occurs only when the pathogenicity of the bacteria surpasses the host’s regular defensive systems. …”
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Astrovirus infection in animals (literature review) by V. A. Mischenko, A. V. Mischenko, Т. B. Nikeshina, О. N. Petrova

“…In recent times, there has been a lot of evidence of occurrence of recombinant astrovirus isolates, which contributes to the emergence of new genetic variants of the pathogen. A wide variety of infected animal species, the genetic diversity of the virus and the recombination events are indicative either of the cross-species transmission and subsequent adaptation of the virus to new hosts, or of the coinfection of the same host with different virus genotypes, which may lead to the emergence of novel astroviruses that are capable of infecting animals or possess a zoonotic potential. …”
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Co‐Translational Deposition of N6‐Acetyl‐L‐Lysine in Nascent Proteins Contributes to the Acetylome in Mammalian Cells by Dingyuan Guo, Nan Li, Xiaoyan Zhang, Runxin Zhou, Jie He, Xiao‐Ping Ding, Weixing Yu, Fuqiang Tong, Sibi Yin, Yu Wang, Xin Xu, Long Wang, Mingzhu Fan, Shan Feng, Ke Liu, Ke Tang, Zhuqing Ouyang, Yusong R Guo, Yugang Wang

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The comparative studies of Borneo plant extracts to increases vaccine efficacy in tilapia, Oreochromis niloticus by Esti Handayani Hardi, Komsanah Sukarti, Maulina Agriandini, Irawan Wijaya Kusuma, Rudi Agung Nugroho

“…Tilapia fish (weight 15 g) were intraperitoneally injected with vaccine mix the extract and challenged at days 7 (d7), 14 (d14), and 21 (d21) post vaccination through intramuscular injection with Aeromonas hydrophila and Pseudomonas fluorescens (105 CFU/mL each pathogen bacteria). The results shown that the fish with BP+V were found in fin rot at d14 days challenge.  …”
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Proteomic analysis of murine norovirus-infected Raw 264.7 cells reveals the induction of Ras GTPases by Sung Ho Yun, Md Arif-Ur Rahman, Soo-Bin Nam, Soo Hyeon Kim, Gyuri Kim, Kun Cho, Jong-Soon Choi

“…Despite being recognized as a water-borne pathogenic virus for a long time, the cellular tropism of norovirus has not yet been clearly explained. …”
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Blocking TNF-α Reduces <i>Leishmania major</i>-Induced Hyperalgesia and Changes the Cytokine Profile in the Paw Skin of BALB/c Mice with a Potential Positive Effect on Parasite Cle... by Muriel Tahtouh Zaatar, Sara Salman, Reem Hoblos, Rabih Roufayel, Ziad Fajloun, Jean-Marc Sabatier, Marc Karam

“…It is widely accepted that INF-γ, TNF-α, and IL-12 usually favor a protective response, while IL-4, IL-5, IL-10, and IL-13 favor a pathogenic one. These and other cytokines also play a major role in <i>Leishmania</i>-induced hyperalgesia via two possible pathways, one involving prostaglandins and the other sympathetic amines as final mediators, preceded by a cascade of cytokines, among which TNF-α seems to play a pivotal role via a still unclear mechanism of action. …”
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Clinical phenotype and trio whole exome sequencing data from a patient with glycogen storage disease IV in Indonesia(NCBI) by Ivan William Harsono, Yulia Ariani, Beben Benyamin, Fadilah Fadilah, Dwi Ari Pujianto, Cut Nurul Hafifah, Titis Prawitasari

“…This often results in delayed diagnosis, typically 5.6 to 7.6 years later, with only 50% of cases being diagnosed, while the remaining cases are classified as undiagnosed rare diseases due to either the absence of identifiable potential variants or the presence of novel variants requiring further functional studies to confirm their pathogenicity. Proband and trio whole exome sequencing analysis remains a cost-effective and widely available method for diagnosing rare diseases detecting between 21 and 40% of cases. …”
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Population Structure Based on Microsatellite Length Polymorphism, Antifungal Susceptibility Profile, and Enzymatic Activity of <i>Candida auris</i> Clinical Isolates in Russia by Ellina Oganesyan, Victoria Klimenteva, Irina Vybornova, Valentina Venchakova, Ekaterina Parshikova, Sergey Kovyrshin, Olga Orlova, Alexander Kruglov, Svetlana Gordeeva, Natalya Vasilyeva, Anastasiya Taraskina

“…<i>Candida auris</i> is an emerging multidrug-resistant fungal pathogen causing nosocomial transmission and invasive infections with high mortality. …”
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SHASI-ML: a machine learning-based approach for immunogenicity prediction in Salmonella vaccine development by Ottavia Spiga, Ottavia Spiga, Ottavia Spiga, Anna Visibelli, Francesco Pettini, Bianca Roncaglia, Annalisa Santucci, Annalisa Santucci, Annalisa Santucci

“…IntroductionAccurate prediction of immunogenic proteins is crucial for vaccine development and understanding host-pathogen interactions in bacterial diseases, particularly for Salmonella infections which remain a significant global health challenge.MethodsWe developed SHASI-ML, a machine learning-based framework for predicting immunogenic proteins in Salmonella species. …”
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TRPV1 Antagonism by Capsazepine Modulates Innate Immune Response in Mice Infected with Plasmodium berghei ANKA by Elizabeth S. Fernandes, Carolina X. L. Brito, Simone A. Teixeira, Renato Barboza, Aramys S. dos Reis, Ana Paula S. Azevedo-Santos, Marcelo Muscará, Soraia K. P. Costa, Claudio R. F. Marinho, Susan D. Brain, Marcos A. G. Grisotto

“…Transient receptor potential vanilloid 1 (TRPV1) modulates macrophage-mediated responses in sepsis, but its role in other pathogenic diseases has never been addressed. We investigated the effects of capsazepine, a TRPV1 antagonist, in malaria. …”
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Evaluation of the Effect of Probiotic Bacillus coagulans Unique IS2 on Mutans Streptococci and Lactobacilli Levels in Saliva and Plaque: A Double-Blind, Randomized, Placebo-Control... by M. Ratna Sudha, Jayanthi Neelamraju, M. Surendra Reddy, Manoj Kumar

“…It is now suggested that probiotic usage prevents the overgrowth of these pathogenic microbes, thereby reducing caries activity. …”
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The Impact of Zinc Supplementation on the Course of Infections by Justyna Woźniak, Ewelina Kopczyńska, Piotr Kulej, Wiktor Biesiada, Justyna Weronika Kmieć, Anna-Mariia Chernysh, Aleksandra Dusińska, Jakub Waszczyński, Kamila Fuczyło, Karolina Stankevič

“…Furthermore, zinc supplementation improved gut microbiome composition, promoting beneficial bacteria and reducing pathogenic growth. Clinical studies confirmed its effectiveness in reducing respiratory infections, improving vaccine responses, and decreasing complications in vulnerable individuals. …”
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Relationship between weapon size and six key behavioural and physiological traits in males of the European earwig by Blackwell, Samantha E M, Pasquier, Laura, Dupont, Simon, devers, Severine, Lecureuil, Charlotte, Meunier, Joël

“…We sampled hundreds of males from two populations, selected 60 males with the longest and shortest forceps from each population, and then measured locomotor performance, boldness, aggregation behaviour, survival under harsh conditions, sperm storage, and survival after pathogen exposure. Contrary to our predictions, we detected no main association between forceps length and the traits measured. …”
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Plasma levels of anti phosphocholine IgM antibodies are negatively correlated with bone mineral density in humans by Michela Palmieri, Spyridoula Maraka, Horace J. Spencer, Jeff D. Thostenson, Katherine Dishongh, Micheal Knox, Betty Ussery, Jesse Byrd, Jacqueline K. Kuipers, Sanaz Abedzadeh-Anaraki, Chitharanjan Duvoor, Yuanjie Mao, Lakshmi Menon, James S. Williams, Stavros C. Manolagas, Robert L. Jilka, Elena Ambrogini

“…It contains a phosphocholine (PC) headgroup and polyunsaturated fatty acids that, when oxidized, form reactive oxidized phospholipids (PC-OxPLs). PC-OxPLs are pathogenic in multiple diseases and neutralized by anti-PC IgM antibodies. …”
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Cutin formation in tomato is controlled by a multipartite module of synergistic and antagonistic transcription factors by Yuan Shi, Changhao Deng, Xiangyin Lu, Yan Wang, Yaowen Pan, Deding Su, Wang Lu, Yuxiang Lin, Rui Li, Junnan Han, Yanwei Hao, Yi Chen, Ghassen Abid, Julien Pirrello, Mondher Bouzayen, Yudong Liu, Zhengguo Li, Baowen Huang

“…Summary: Cuticles protect plants from water loss and pathogen attack. We address here the functional significance of SlGRAS9, SlZHD17, and SlMBP3 in regulating cutin formation in tomato fruit. …”
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Exogenous dsRNA triggers sequence-specific RNAi and fungal stress responses to control Magnaporthe oryzae in Brachypodium distachyon by Ying Zheng, Benjamin Moorlach, Desiree Jakobs-Schönwandt, Anant Patel, Chiara Pastacaldi, Stefan Jacob, Ana R. Sede, Manfred Heinlein, Minna M. Poranen, Karl-Heinz Kogel, Maria Ladera Carmona

“…We demonstrate that Magnaporthe oryzae (Mo), a globally significant crop pathogen, internalizes dsRNA across a broad size range of 21 to about 3000 bp. …”
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Identification of a Fetal De Novo Splice Variant in ARCN1 Associated With Growth and Skeletal Abnormalities by Wencong He, Zejun Yang, Jianjian Cui, Ruilin Ma, Hui Tao, Yanan Li, Yin Zhao, Yang Pan, Jue Li

“…The clinical and genetic data of a fetus with a complex combination of clinical signs and a novel de novo heterozygous variant were collected and have been summarized in this study. The potential pathogenic variant was identified throughout the whole exome sequencing and the effects of candidate variants were further validated by a minigene splicing assay. …”
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The regulation of tobacco growth under preceding crop planting: insights from soil quality, microbial communities, and metabolic profiling by Peiyan Zhao, Houfa Zhou, Xiaolin Liao, Leifeng Zhao, Yuanxian Zheng, Tiane Xiong, Gaorun Zhang, Sirong Jiang, Jiming Wang, Yuansheng He, Jiangtao Li, Jieying Zhu, Yongjun Zhang, Yanrun Li, Fuzhao Nian, Di Liu

“…In contrast, the preceding crop of maize reduced plant pathogenic fungi and promoted positive microbial interactions. …”
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Inovirus-Encoded Peptides Induce Specific Toxicity in <i>Pseudomonas aeruginosa</i> by Juehua Weng, Yunxue Guo, Jiayu Gu, Ran Chen, Xiaoxue Wang

“…<i>Pseudomonas aeruginosa</i> is a common opportunistic pathogen associated with nosocomial infections. The primary treatment for infections typically involves antibiotics, which can lead to the emergence of multidrug-resistant strains. …”
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