Rotavirus in Calves and Its Zoonotic Importance by Umer Seid Geletu, Munera Ahmednur Usmael, Fufa Dawo Bari

“…Rotavirus is a major pathogen responsible for diarrheal disease in calves, resulting in loss of productivity and economy of farmers. …”
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Purification and Characterization of a New Lectin from Loach Skin Mucus by Peng-peng Sun, Yuan-yuan Ren, Jie Zheng, Ai-jun Hu

“…Lectin from loach skin mucus plays an important role in pathogen defense. However, hardly can any paper relevant to the character of lectin from loach skin mucus be found in recent years. …”
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Drug Target Identification and Elucidation of Natural Inhibitors for : An Study by Surya Narayan Rath, Manisha Ray, Animesh Pattnaik, Sukanta Kumar Pradhan

“…Identification of potential drug target and proposing a novel lead compound against the pathogen has a great aid and value. In this study, bioinformatics tools and technology have been applied to suggest a potential drug target by screening the proteome information of B. petrii DSM 12804 (accession No. …”
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Occurrence of antibiotics and antibiotic resistance genes at various stages of different aquaculture modes surrounding Tai Lake, China by Congcong Wu, Congcong Wu, Haitao Ye, Mingzhu Xu, Xuan Zhao, Xuejie Zhao, Lina Li, Mingzhi Li, Yanfei Wei, Yuru Li, Baolan Hu, Baolan Hu

“…Microbial diversity also varies seasonally, especially with a gradual increase in the abundance of some pathogenic bacteria (Flavobacterium). Antibiotics and resistance genes were found at higher levels in fish ponds compared to shrimp and crab ponds, while they were lower in shrimp and crab ponds that utilized the ecological mode ponds than in the traditional culture mode ponds.ConclusionOur study presents a comprehensive characterization of antibiotics and ARGs in aquaculture waters from various perspectives. …”
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Modern approaches to production of safe and effective genetically modified rabies vaccines for animals by M. I. Doronin, A. Mazloum, D. V. Mikhalishin, M. N. Mitrofanova, A. Yu. Sukharkov, V. V. Kiseleva, A. V. Sprygin

“…Taking into account that there is a lack of affordable high-quality vaccines to globally prevent and control the disease, stable, attenuated production strains of rabies virus with broad cross-activity against various variants of the pathogen shall be considered as ideal candidates to produce high-quality, safe and effective vaccines. …”
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Analysis of the Control Effect of <i>Bacillus amyloliquefaciens</i> C4 Wettable Powder on Potato Bacterial Wilt Caused by <i>Ralstonia solanacearum</i> by Zhixiang Xing, Dan Liu, Meng Luo, Zelin Yang, Wenyuan Pang, Yexing Feng, Jiani Yan, Fumeng He, Xu Feng, Qiang Yuan, Yingnan Wang, Fenglan Li

“…The physiological and biochemical results showed that C4 wettable powder could induce rapid defense enzyme responses in leaves and enhance plant resistance to pathogenic bacteria. The results showed that C4 wettable powder effectively controlled potato bacterial wilt, and its application method was determined.…”
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Chikungunya intra-vector dynamics in Aedes albopictus from Lyon (France) upon exposure to a human viremia-like dose range reveals vector barrier’s permissiveness and supports local... by Viginier, Barbara, Cappuccio, Lucie, Garnier, Céline, Martin, Edwige, Maisse, Carine, Valiente Moro, Claire, Minard, Guillaume, Fontaine, Albin, Lequime, Sébastian, Ratinier, Maxime, Arnaud, Frédérick, Raquin, Vincent

“…Arbovirus emergence and epidemic potential, as approximated by the vectorial capacity formula, depends on host and vector parameters, including the vector’s intrinsic ability to replicate then transmit the pathogen known as vector competence. Vector competence is a complex, time-dependent, quantitative phenotype influenced by biotic and abiotic factors. …”
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16S rRNA and Omp31 Gene Based Molecular Characterization of Field Strains of B. melitensis from Aborted Foetus of Goats in India by Ajay Singh, Vivek Kumar Gupta, Amit Kumar, Vikas Kumar Singh, Shivasharanappa Nayakwadi

“…In human, it is mainly caused by Brucella melitensis, a natural pathogen for goats. In India, a large number of goats are reared in semi-intensive to intensive system within the close vicinity of human being. …”
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Association of Neovascular Glaucoma with Risk of Stroke: A Population-Based Cohort Study by Cheng-Wen Su, Yue-Cune Chang, Cheng-Li Lin, Hsin-Yi Chen

“…Based on the similar pathogenic mechanisms of NVG and ischemic stroke, we investigated the relationship between NVG and stroke by using a nationally representative sample. …”
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Unlocking precision medicine: clinical applications of integrating health records, genetics, and immunology through artificial intelligence by Yi-Ming Chen, Tzu-Hung Hsiao, Ching-Heng Lin, Yang C. Fann

“…Deep learning techniques have significantly advanced variant calling, pathogenicity prediction, splicing analysis, and MHC-peptide binding predictions in genetics. …”
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Peptide-Based Vaccination Therapy for Rheumatic Diseases by Bin Wang, Shiju Chen, Qing Zheng, Yuan Liu, Guixiu Shi

“…Peptide-based active vaccination against pathogenic cytokines such as TNF-α and interferon-α (IFN-α) is shown to be promising in treating RA or SLE. …”
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NLRP3 Is Expressed in the Spiral Ganglion Neurons and Associated with Both Syndromic and Nonsyndromic Sensorineural Deafness by Penghui Chen, Longxia He, Xiuhong Pang, Xiaowen Wang, Tao Yang, Hao Wu

“…In this study, we performed comprehensive genetic screening in a dominant family in which the proband was initially diagnosed with nonsyndromic deafness. No pathogenic mutation was identified by targeted NGS in 72 nonsyndromic and another 72 syndromic deafness genes. …”
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Microbiological Hazard Identification and Exposure Assessment of Poultry Products Sold in Various Localities of Hyderabad, India by Rao V. Sudershan, R. Naveen Kumar, L. Kashinath, V. Bhaskar, K. Polasa

“…The most prevalent pathogenic bacteria isolated were S. aureus (3.4 log 10 cfu/g) and B. cereus (3.4 log 10 cfu/g). …”
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An Improved Sporulation Method for Producing Asexual Zoospores of Pythium aphanidermatum on Culture Medium by Yu Jin Kim, Seung Hyo Baek, Elena Volynchikova, Mee Kyung Sang, Ki Deok Kim

“…These findings suggest that our sporulation method can help obtain adequate zoospores for various basic and applied studies, including pathogen identification, virulence assessment, resistance resource screening, and control strategy development.…”
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Folate alleviated skin inflammation and fibrosis resulting from impaired homocysteine metabolism by Jiefeng Huang, Wuyan Lu, Shenli Zhao, Zixin Cai, Linxiao Li, Zihao Hu, Yu Jiang, Jinyi Deng, Yiming Tang, Chenzhang Shi, Chen Wang, Guangpeng Liu, Shuaijun Li

“…However, it remains unclear whether Hcy accumulation plays a pathogenic role in skin fibrosis. Here, we report that Hcy metabolism in fibroblasts plays a crucial role in regulating the pathogenesis of skin fibrosis. …”
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TACSTD2 in gelatinous drop-like corneal dystrophy: variant functional analysis and expression in the cornea after limbal stem cell transplantation by Liubov O. Skorodumova, Ekaterina N. Grafskaia, Daria D. Kharlampieva, Dmitry I. Maltsev, Tatiana V. Petrova, Alexandra V. Kanygina, Elena V. Fedoseeva, Pavel V. Makarov, Boris E. Malyugin

“…GDLD is characterized by the loss of barrier function in corneal epithelial cells (CECs) and amyloid deposition due to pathogenic variants in the TACSTD2 gene. Limbal stem cell transplantation (LSCT) has been suggested as an effective therapeutic alternative for patients with GDLD. …”
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An Enigmatic Wild Passerine Mortality Event in the Eastern United States by Sabrina S. Greening, Julie C. Ellis, Nicole L. Lewis, David B. Needle, Cristina M. Tato, Susan Knowles, Valerie Shearn-Bochsler, Jaimie L. Miller, Daniel A Grear, Jeffrey M. Lorch, David S. Blehert, Caitlin Burrell, Lisa A. Murphy, Erica A. Miller, C. Brandon Ogbunugafor, Andrea J. Ayala, W. Kelley Thomas, Joseph L. Sevigny, Lawrence M. Gordon, Tessa Baillargeon, Lusajo Mwakibete, Megan Kirchgessner, Christine L. Casey, Ethan Barton, Michael J. Yabsley, Eman Anis, Roderick B. Gagne, Patrice Klein, Cindy Driscoll, Chelsea A. Sykes, Robert H. Poppenga, Nicole M. Nemeth

“…Extensive diagnostic evaluations failed to identify a causative pathogen or other etiology, although congruent results across laboratories have helped drive further investigation into alternative causes, such as nutritional deficiencies. …”
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Overcoming beta-lactam resistance in Pseudomonas aeruginosa by targeting metallo-beta-lactamase VIM-1: a one-microsecond molecular dynamics simulation study by Mohammed Salleh M. Ardawi, Samar A. Badreddine, Muhammad Yasir, Muhammad Yasir, Aiah M. Khateb, Aiah M. Khateb, Safaa A. Turkistani, Ahmed Afandi, Samah O. Noor, Adhari Alselmi, Adhari Alselmi, Vivek Dhar Dwivedi, Vivek Dhar Dwivedi, Esam I. Azhar, Esam I. Azhar

“…Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen with a high resistance to beta-lactam antibiotics, mainly due to the production of metallo-beta-lactamase VIM-1 (MBL-VIM-1) enzyme. …”
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Inhibition of Staphylococcus aureus α-Hemolysin Production Using Nanocurcumin Capped Au@ZnO Nanocomposite by Majid S. Jabir, Taha M. Rashid, Uday M. Nayef, Salim Albukhaty, Faizah A. AlMalki, Jawaher Albaqami, Amal A. AlYamani, Zainab J. Taqi, Ghassan M. Sulaiman

“…These NPs may offer a new strategy in combating pathogen infections and in the future for biomedical and pharmaceutical applications.…”
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Microbial Community, Fatty Acid Composition, and Health Potential of Horse Oil Fermented with Barley Nuruk by Jeong-Ha Lee, Sung-Eun Bae, Ho-Min Kang, Yu-Jin Ha, Chang-Gu Hyun

“…Next-generation sequencing (NGS) analysis showed a notable reduction in pathogenic bacteria, such as <i>Salmonella enterica</i>, and a dominance of <i>Lactobacillus acidophilus</i> (95.2%) by day 10. …”
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