Potency of the Consortium of Pseudomonad fluorescent pf-142 and Bacillus mycoides Isolates Against Bacterial Wilt Disease In-Vitro by Yosua Nathanael Itona Sagala, Endang Triwahyu Prasetyawati, Yenny Wuryandari

“…The variables observed were the symptoms of attack and pathogenicity of R. solanacearum, compatibility and inhibitory rate of the consortium of Pseudomonad fluorescens pf-142 and B. mycoides against R. solanacearum. …”
Get full text

YgaE Regulates Out Membrane Proteins in Salmonella enterica Serovar Typhi under Hyperosmotic Stress by Min Wang, Ping Feng, Xun Chen, Haifang Zhang, Bin Ni, Xiaofang Xie, Hong Du

“…Typhi) is a human-specific pathogen that causes typhoid fever. In this study, we constructed ΔygaE mutant and a microarray was performed to investigate the role of ygaE in regulation of gene expression changes in response to hyperosmotic stress in S. …”
Get full text

Microbial Translocation in Chronic Liver Diseases by Marilia Rita Pinzone, Benedetto Maurizio Celesia, Michele Di Rosa, Bruno Cacopardo, Giuseppe Nunnari

“…The intestinal microflora is not only involved in the digestion of nutrients, but also in local immunity, forming a barrier against pathogenic microorganisms. The derangement of the gut microflora may lead to microbial translocation, defined as the passage of viable microorganisms or bacterial products (i.e., LPS, lipopeptides) from the intestinal lumen to the mesenteric lymph nodes and other extraintestinal sites. …”
Get full text

Antimicrobial activity of Chitosan-silver nanoparticles made from jewelry industry silver waste by Perdana Muhammad Iqbal, Kusuma Ikhwan Yuda, Dwandaru Wipsar Sunu Brams, Yulianti Evy, Tóth Barbara, Csupor Dezső, Takó Miklós, Vágvölgyi Csaba

“…This study aimed to synthesize chitosan-silver nanoparticles (CS-AgNPs) from reusable silver waste of the jewelry industry and investigate their antimicrobial properties against pathogenic microorganisms. X-Ray diffraction (XRD) analysis was used to confirm the crystalline structure of the recycled silver, with a strong diffraction peak observed at 2θ=38.60°. …”
Get full text

Identification of a comprehensive set of transcriptional regulators involved in the long-term survivability of Escherichia coli in soil by Soma Nakamoto, Ikki Kobayashi, Koichi Watanabe, Takeru Kikuta, Sousuke Imamura, Tomohiro Shimada

“…These transcription factors are often global regulators and conserved among other pathogenic bacterial species. Taken together, we successfully identified a comprehensive set of transcription factors involved in the long-term survival of E. coli in soil. …”
Get full text

Preparation and Antibacterial Activity of Mixed Ligand Complexes of Co(II), Ni(II), Cu(II) and Cd(II) Derived from 1-Phenylazo-2-naphthol and Salicylaldehyde by S. A. I. Sharif, A. N. El-Tajoury, A. A. Elamari

“…The ligands and mixed ligand complexes have been tested on antibacterial activity against three strains of pathogenic bacteria such as Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa…”
Get full text

Prevalence of red, orange, and green microbial complexes in periodontal pockets of chronic kidney disease patients on hemodialysis: a systematic review and meta-analysis by Diego José Gambin, Jayne de Oliveira Manica, Daniela Dal Olmo Merib, Caroline Mirek, Felipe Gomes Dallepiane, Thais Mageste Duque, João Paulo De Carli, Micheline Sandini Trentin

“…In the subgingival microbiota of CKD patients on hemodialysis, the red complex showed higher rates and prevalences, and Tannerella forsythia was the most common pathogen. …”
Get full text

Immune Modulation as Adjunctive Therapy for Pneumocystis pneumonia by Jing Wang, Terry W. Wright, Francis Gigliotti

“…Pneumocystis is an opportunistic fungal respiratory pathogen that causes life-threatening pneumonia (Pcp) in patients suffering from defects in cell-mediated immunity, including those with acquired immunodeficiency syndrome (AIDS) and immunosuppression secondary to chemotherapy or organ transplantation. …”
Get full text

MicroRNAs in Diabetic Kidney Disease by Rong Li, Arthur C. K. Chung, Xueqing Yu, Hui Y. Lan

“…Therefore, identification of the pathogenic role of microRNAs possesses an important clinical impact in terms of prevention and treatment of progression in diabetic kidney disease because it allows us to design novel and specific therapies and diagnostic tools for diabetic kidney disease.…”
Get full text

Oxidative Stress Biomarkers: Establishment of Reference Values for Isoprostanes, AOPP, and NPBI in Cord Blood by Mariangela Longini, Elisa Belvisi, Fabrizio Proietti, Francesco Bazzini, Giuseppe Buonocore, Serafina Perrone

“…Oxidative stress (OS) is a common pathogenic factor involved in the onset of several diseases in humans, from immunologic disorders to malignancy, being a serious public health problem. …”
Get full text

Risk of Fungal Infection to Dental Patients by Jaqueline Lopes Damasceno, Rafael Aparecido dos Santos, Amir Horiquini Barbosa, Luciana Assirati Casemiro, Regina Helena Pires, Carlos Henrique Gomes Martins

“…Fungi can cause various diseases, and some pathogenic fungi have been detected in the water of dental equipment. …”
Get full text

Pyogenic Spondylodiscitis due to Streptococcus constellatus in an Immunocompromised Male Patient: A Case Report and Review of the Literature by Charalampos Potsios, Panagiota Xaplanteri, Vasileios Zoitopoulos, Panagiotis Patrinos, Iro Ioanna Giannakopoulou, Ilektra Tzivaki, Theodora Kafentzi, Konstantina Samanta, Konstantina Filioti, Panagiotis Sideris, Konstantinos Letsas, Konstantinos Koukios

“…S. constellatus is an extremely rare pathogen and to our knowledge only two other cases of pyogenic spondylodiscitis are reported in the literature. …”
Get full text

Functional Role of Adult Hippocampal Neurogenesis as a Therapeutic Strategy for Mental Disorders by Heechul Jun, Syed Mohammed Qasim Hussaini, Michael J. Rigby, Mi-Hyeon Jang

“…Establishing a significant role of adult neurogenesis in the pathogenicity of psychiatric disorders may hold the key to potential strategies toward effective treatment.…”
Get full text

Highly effective treatment of bacterial infection-accompanied wounds by fat extract-embedded phototherapeutic hydrogel by Haonan Wang, Yingnan Xiao, Deli Zhuge, Genghe Shi, Chengping Liu, Hui Liang, Jing Wu, Yunxuan Huang, Yilin Xie, Chunnan Hu, Jiafeng Xie, Xinyi Wang, Yao Yao, Fang Wang, Xufei Zhang, Chengke Huang, Yingzheng Zhao, Weiyang Meng, Yijie Chen, Mengchun Chen

“…Overall, the nanoparticle-hydrogel superstructure shows promise for treating local pathogen-infected wounds.…”
Get full text

Parity-Dependent Hemosiderin and Lipofuscin Accumulation in the Reproductively Aged Mouse Ovary by Ulises Urzua, Carlos Chacon, Renato Espinoza, Sebastián Martínez, Nicole Hernandez

“…Since lipofuscin is a widely accepted senescence marker and given the recently postulated role of lipofuscin-associated iron as a source of reactive oxygen species (ROS) in senescent cells, these findings suggest a possible pathogenic mechanism by which nulliparity contributes to an increased OC risk in the postmenopausal ovary.…”
Get full text

Substantiation of application and estimation of efficacy of probiotics at inflammatory bowel diseases by Ye. A. Poluektova, Yu. O. Sidorina, S. Yu. Kuchumova, A. V. Korolev, O. S. Shifrin

“…At patients with IBD the intestinal microbiome have quantitative and qualitative differences from microbiome of healthy patients aside of increase in contents of opportunistic and pathogenic microorganisms. Microbiome changes result in initiation of cascade of pathological immune reactions of the host in related to presence of genetical defects, that, in turn, promotes development of clinical symptoms and morphological changes in intestinal wall. …”
Get full text

Natural Killer T (NKT) Cells and Periodontitis: Potential Regulatory Role of NKT10 Cells by Samanta Melgar-Rodríguez, Emilio A. Cafferata, Nicolás I. Díaz, Miguel A. Peña, Luis González-Osuna, Carolina Rojas, Alfredo Sierra-Cristancho, Angélica M. Cárdenas, Jaime Díaz-Zúñiga, Rolando Vernal

“…In the present review, we revise and discuss the pathogenic characteristics of NKT cells in these diseases and their role in the pathogenesis of periodontitis; particularly, we analyze the potential regulatory role of the IL-10-producing NKT10 cells.…”
Get full text

Persistent Cutibacterium (Formerly Propionibacterium) acnes Bacteremia and Refractory Endocarditis in a Patient with Retained Implantable Pacemaker Leads by M. Freedman, J. O. Aflatooni, R. Foster, P. G. Haggerty, C. J. Derber

“…The patient in this report demonstrates how cardiac device-related endocarditis secondary to C. acnes can be overlooked due to the indolent nature of this pathogen. This patient presented with an implanted cardiac pacemaker device, as well as retained leads from a prior pacemaker. …”
Get full text

The Contribution of α-Synuclein Spreading to Parkinson’s Disease Synaptopathy by Francesca Longhena, Gaia Faustini, Cristina Missale, Marina Pizzi, PierFranco Spano, Arianna Bellucci

“…Synaptopathies are diseases with synapse defects as shared pathogenic features, encompassing neurodegenerative disorders such as Parkinson’s disease (PD). …”
Get full text

Retinitis Pigmentosa and Bilateral Idiopathic Demyelinating Optic Neuritis in a 6-Year-Old Boy with OFD1 Gene Mutation by Xun Wang, Cong Zheng, Wen Liu, Hui Yang

“…Nevertheless, the pathogenicity of the variant needs further confirmation.…”
Get full text