Nitazoxanide in Acute Rotavirus Diarrhea: A Randomized Control Trial from a Developing Country by Samarendra Mahapatro, Nijwm Mahilary, Amit Kumar Satapathy, Rashmi Ranjan Das

“…Acute diarrhea is one of the leading causes of childhood mortality, with rotavirus being an important pathogen. Nitazoxanide, an antiparasitic agent, has been shown to inhibit rotavirus. …”
Get full text

Identifying Safeguards Disabled by Epstein-Barr Virus Infections in Genomes From Patients With Breast Cancer: Chromosomal Bioinformatics Analysis by Bernard Friedenson

“…Breakpoint distributions in breast and EBV-associated cancers on some chromosomes were not confidently distinguished (P ConclusionsEBV infection predisposes one to breast cancer and metastasis, even if the virus disappears. Identifying this pathogenic viral damage may improve screening, treatment, and prevention. …”
Get full text

The Interplay Between Viral Infection and Cell Death: A Ping-Pong Effect by Alireza Nourazarian, Hadi Yousefi, Cigir Biray Avci, Behrouz Shademan, Emad Behboudi

“…This study emphasizes the importance of investigating the mechanisms by which viruses control the host’s PCD machinery to gain insight into the evolutionary dynamics of host-pathogen interactions and to develop new approaches for predicting and managing viral threats. …”
Get full text

Recent Advances in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms by Hideaki Watanabe

“…TNF-α and TARC levels also reflect therapeutic responses and may be useful markers of the DIHS disease process. Recently, the pathogenic mechanism of T-cell activation triggered by human leukocyte antigen- (HLA-) restricted presentation of a drug or metabolites was elucidated. …”
Get full text

Culturable Bacterial Communities Related to Different Larval Stages of Sanys irrosea (Guenee, 1852) (Lepidoptera: Noctuoidae) by Elif Sevim, Ali Sevim

“…In addition, some potential slug, human and plant pathogenic bacteria (Moraxella osloensis, Kocuria rosea and Clavibacter michi-ganensis) were isolated. …”
Get full text

PERBANDINGAN KEMAMPUAN EKSTRAK KULIT PISANG AGUNG SEMERU DAN PISANG MAS KIRANA VARIETAS LUMAJANG DALAM MENGHAMBAT PERTUMBUHAN Candida albicans by Dwi Nur Rikhmasari

“…The purpose of this research is to know the difference of banana extract of Agung Semeru and banana Mas Kirana varieties of lumajang, in inhibiting the growth of pathogenic fungi Candida albicans, and to know the optimal concentration which can inhibit the growth of Candida albicans. …”
Get full text

Health in Swedish integration policies – a discourse analysis by Sara Svanholm, Heidi Carlerby, Eija Viitasara

“…The analysis of the documents showed how the health discourses were expressed in the form of the medicalisation of health, the individualisation of health and the risk of ill health. A pathogenic approach to health was visible in the policies and individual disease prevention or rehabilitation was the main health focus. …”
Get full text

The Role of TLR2, TLR4, and TLR9 in the Pathogenesis of Atherosclerosis by Mohsin H. K. Roshan, Amos Tambo, Nikolai P. Pace

“…They are expressed by a variety of immune cells where they recognize pathogen-associated molecular patterns (PAMPs). TLRs recruit adaptor molecules, including myeloid differentiation primary response protein (MYD88) and TIRF-related adaptor protein (TRAM), to mediate activation of MAPKs and NF-kappa B pathways. …”
Get full text

COVID-19: Lessons from the Past to Inform the Future of Healthcare by Camilla Mattiuzzi, Giuseppe Lippi

“…The key issues that hindered an effective response to coronavirus disease 2019 (COVID-19) are numerous and multifaceted, and some of these will be critically examined in this article, including delayed identification of the pathogen, inadequate public health preparedness, inadequate therapeutic management, and deficiencies in laboratory diagnostics. …”
Get full text

Novel anti-inflammatory properties of mannose oligosaccharides in the treatment of inflammatory bowel disease via LGALS3 modulation by Yaqi Du, Yan Fan, Xin Li, Fenqin Chen

“…Employing both in vitro and in vivo models, we explored how GA-MOS influences microbial communities, particularly focusing on their capacity to enhance health-associated bacteria and reduce pathogenic species within the gut environment. Our findings reveal that GA-MOS treatment significantly altered the gut microbiota composition, increasing the abundance of anti-inflammatory bacteria while decreasing pro-inflammatory species, thus contributing to a reduction in gut inflammation and an improvement in intestinal barrier function. …”
Get full text

Contamination with escherichia coli of homemade fresh butter in rural areas of ferizaj and gjilan in kosovo by Enver Bajrami, Kapllan Sulaj

“…<p> <b> Conclusions:</b> Homemade fresh butter produced from fresh cows milk in rural areas of Kosovo is commonly contaminated with different kinds of microorganisms as well as by pathogenic strains of E. coli. The poor hygienic home conditions in some rural areas in Kosovo have impact in the butter quality and are associated with the increasing number of E. coli.…”
Get full text

It Is All in the Genes: A Story of Unexpected Survival in a 67-Year-Old Male with Metastatic Pancreatic Cancer by Patsy W. P. Lee, Scott W. Strum, Elena Tsvetkova

“…Genetic testing revealed a pathogenic heterozygous germline BRCA2 6643delT p.(Tyr2215Thrfs∗14) frameshift mutation and somatic GNAS 2531G>A p.…”
Get full text

The chemistry of gut microbiome in health and diseases by Agnes Wei Yin Lau, Loh Teng-Hern Tan, Nurul-Syakima Ab Mutalib, Sunny Hei Wong, Vengadesh Letchumanan, Learn-Han Lee

“…The balance between protective and pathogenic microbes must be kept in check to prevent disease onset. …”
Get full text

The Role of Combining Probiotics in Preventing and Controlling Inflammation: A Focus on the Anti-Inflammatory and Immunomodulatory Effects of Probiotics in an In Vitro Model of IBD by Shadi Aghamohammad, Amin Sepehr, Seyedeh Tina Miri, Saeideh Najafi, Mohammad R. Pourshafie, Mahdi Rohani

“…A quantitative real-time polymerase chain reaction (qPCR) assay was conducted to analyze the expression of JAK/STAT and inflammatory genes after treatment with the probiotic mixture before, after, and simultaneously with the sonicated pathogen in the HT-29 cell line. The production of IL-6 and IL-1β after probiotic treatment was investigated via cytokine assay. …”
Get full text

Bioconversion of Keratin Wastes Using Keratinolytic Microorganisms to Generate Value-Added Products by Muhammed Seid Anbesaw

“…Due to the introduction of this waste associated with different pathogenic organisms into soil and water bodies, human beings and other small and large animals are affected by different diseases. …”
Get full text

PEDIATRIC ENTEROCOLITIS: CLINICAL MANIFESTATIONS AND MANAGEMENT STRATEGIES by Ginel Baciu, Carmen Baciu, Cristina Maria Mihai, Tatiana Chisnoiu, Ramona Mihaela Stoicescu, Adriana Luminita Balasa, Adriana Mocanu, Lorenza Forna, Alexandru Paul Baciu

“…Rotavirus is a significant pathogen contributing to dehydrating diarrhea and hospitalizations in children under five. …”
Get full text

A Prospective Study of Clinical Features of Anterior Uveitis in Taiwan by Wei-Yu Chiang, Shih-Chou Chen, Shwu-Jiuan Sheu, Hsi-Kung Kuo

“…Among patients with herpetic AU, cytomegalovirus (CMV) was the most common pathogen (17/21, 81%). Compared to HLA-B27-associated acute AU, CMV-related AU was mostly observed in patients that were older in age, exhibited higher intraocular pressure, more keratic precipitates, greater iris atrophy, and more pseudophakia, but was least reported in those with posterior synechiae. …”
Get full text

A Comprehensive Review of the Development and Therapeutic Use of Antivirals in Flavivirus Infection by Aarti Tripathi, Shailendra Chauhan, Renu Khasa

“…Understanding the mechanisms of host–pathogen interaction, host immunity, viral immune evasion, and disease pathogenesis is highly warranted to foster the development of antivirals. …”
Get full text

Invasive Listeriosis of Intracardiac Device by Prerna Sharma, Mohamed Yassin

“…Listeria monocytogenes is a food-borne pathogen which can cause invasive infection in immunocompromised adults. …”
Get full text

Isolation, Identification, and Characterization of Bacterial Isolates in Garlic, Ginger, Pepper, and Turmeric Commonly Traded Within Ilorin, Kwara State, Nigeria by A. E. Ajiboye, M. O. Jimoh, B. A. Hammed, T. E. Adesokan

“…The presence of various pathogenic bacteria in the food condiments analyzed raises concern on their impact to the health of the consumers and these food spices could also serve as a vehicle for the transmission of disease causing bacteria. …”
Get full text