Niobium Uptake and Release by Bacterial Ferric Ion Binding Protein by Yanbo Shi, Ian Harvey, Dominic Campopiano, Peter J. Sadler

“…The possibility of designing niobium-based antibiotics which block iron uptake by pathogenic bacteria is discussed.…”
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Genome rearrangements in neurodevelopmental disorders of the central nervous system: origins, genomic mechanisms, functional and clinical consequences. Review article by V. Kučinskas, E. Preikšaitienė, L. Ambrozaitytė, L. Cimbalistienė, A. Utkus

“…In our research, the detection of chromosomal aberrations by molecular karyotyping and whole exome sequencing capable of uncovering pathogenic variants in any of the human genes were the main technologies used to identify the molecular causes of intellectual disability. …”
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Examination of Molecular Effects of MYLK Deletion in a Patient with Extensive Aortic, Carotid, and Abdominal Dissections That Underlie the Genetic Dysfunction by Sarah K. Macklin, Katelyn A. Bruno, Charitha Vadlamudi, Haytham Helmi, Ayesha Samreen, Ahmed N. Mohammad, Stephanie Hines, Paldeep S. Atwal, Thomas R. Caulfield

“…Through a combined multiomic approach of clinical, functional, and protein informatics, we arrive at a data fusion for determination of pathogenicity embedded within the genetic code for this particular genetic variant, which, as a platform, continues to broaden its scope across the field of variants of uncertain significance classification.…”
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IgG4-Related Disease Presenting as Isolated Scleritis by Eran Berkowitz, Ella Arnon, Alona Yaakobi, Yuval Cohen, Beatrice Tiosano

“…This case highlights the significance of IgG4-RD in the differential diagnosis of scleritis and raises the question as to whether various organs affected by IgG4-RD may have different underlying pathophysiological mechanisms in which pathogenic T cells play a role.…”
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Gut microbiome diversity as adjuvant marker for immune function by Mahdaleny, Febriana Catur Iswanti

“…Mucin, bacterial polysaccharides, and protein combine to form a unique mucosal biofilm that serves as a home for a variety of commensal and pathogenic organisms in the host. Maintaining proper mucosal barrier function is vital for both GI and systemic health. …”
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Genetic Diversity of Toll-Like Receptors and Immunity to M. leprae Infection by Bryan E. Hart, Richard I. Tapping

“…Toll-like receptors (TLRs) have emerged as an essential family of innate immune pattern recognition receptors which play a pivotal role in host defense against microbes, including pathogenic strains of mycobacteria. This paper will highlight studies which have uncovered the association of specific TLR gene polymorphisms with leprosy or tuberculosis: two important diseases resulting from mycobacterial infection. …”
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Bacterial Vaginosis Bacterial and Epithelial Cell Adhesion Molecules by Şayeste Demirezen, Aydan Mutlu, Sinan Beksaç

“…They maintain low pH of vaginal discharge by metabolising glycogen in vaginal epithelial cell and protects the vagina against the pathogenic microorganisms. However, the vaginal flora can be changed because of birth, taking antibiotics and contraceptive pills. …”
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Angular Leaf Spot: A Bacterial Disease in Strawberries in Florida by Natalia A. Peres, Silvia I. Rondon, James F. Price, Daniel J. Cantliffe

“… Angular Leaf Spot (ALS) is a bacterial disease caused by Xanthomonas fragariae Kennedy & King, a pathogen highly specific to wild and cultivated strawberry, Fragaria x ananassa Duchesne (Legard et al. 2003). …”
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Hepatoprotective Potential of Sargassum muticum against STZ-Induced Diabetic Liver Damage in Wistar Rats by Inhibiting Cytokines and the Apoptosis Pathway by Mohammed M. Safhi, Mohammad Firoz Alam, Sivagurunathan Moni Sivakumar, Tarique Anwer

“…Thus, the MESM plays a key role in rejuvenating the liver and can modulate diabetes’s pathogenic effect by reducing the glucose level.…”
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Melatonin and its therapeutic prospects in gastroenterology by A. A. Svistunov, Mikhail A. Osadchuk, A. M. Osadchuk

“…Adaptive properties of melatonin allow to recommend its therapeutic application at various disease groups as pathogenic treatment within basic modes of treatment.…”
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Saliva: Physiology and Diagnostic Potential in Health and Disease by Sebastien J. C. Farnaud, Ourania Kosti, Stephen J. Getting, Derek Renshaw

“…Communicable disease is the focus of the next section where we review the literature relating to the direct and indirect detection of pathogenic infections from human saliva. Finally, we discuss hormones involved in appetite regulation and whether saliva is a viable alternative to blood in order to monitor hormones that are involved in satiety.…”
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Extradigestive Manifestation of Helicobacter Pylori Infection in Children and Adolescents by Philip M Sherman, Frank YH Lin

“…Helicobacter pylori infection fulfills each of Koch's postulates as a human pathogen causing chronic active gastritis. Disease consequences that develop in a subset of infected subjects include peptic ulcerations, gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. …”
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Neuropsychiatric Disorder Associated with Group G Streptococcus Infection by Rie Okumura, Sawako Yamazaki, Tsukasa Ohashi, Shinichi Magara, Jun Tohyama, Hiroshi Sakuma, Masaharu Hayashi, Akihiko Saitoh

“…The present findings suggest that neuropsychiatric disorders can result from GGS infection and that the pathogenic mechanism is similar to that of GABHS infection. …”
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Mycophenolate Mofetil and Clostridium difficile-associated Colitis by A. I. Dolgushina, A. A. Selyanina, E. A. Mezenceva, A. G. Vasilenko, L. I. Pozdeeva, L. Yu. Zhuravleva, E. R. Olevskaya, E. A. Fedorova

“…Catarrhal ulcerative colitis in colonoscopy, C. difficile toxins in pathogen stool panel. Ulcerative, ischaemic colitises and the graft-versus-host disease were ruled out in examination. …”
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Marine natural products as an important source of bioactive substances for non-alcoholic fatty liver disease management by Menglei Shi, Menglei Shi, Sisi Chen, Sisi Chen, Yutong Feng, Yutong Feng, Shiyuan Wang, Yuyu Xia, Jianlin He

“…A brief overview of the predominant pathogenic mechanisms underlying the disease is also provided, thereby establishing a critical link between the therapeutic potential of marine bioactive substances and the management of NAFLD.…”
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Two-Component Signal Transduction System SaeRS Positively Regulates Staphylococcus epidermidis Glucose Metabolism by Qiang Lou, Yijun Qi, Yuanfang Ma, Di Qu

“…Staphylococcus epidermidis, which is a causative pathogen of nosocomial infection, expresses its virulent traits such as biofilm and autolysis regulated by two-component signal transduction system SaeRS. …”
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Modulation of Immunoregulatory Properties of Mesenchymal Stromal Cells by Toll-Like Receptors: Potential Applications on GVHD by Bruno Sangiorgi, Rodrigo Alexandre Panepucci

“…The present review addresses how Pathogen-Associated Molecular Patterns (PAMPS) modulate the immunosuppressive phenotype of human MSCs by signaling through Toll-like receptors (TLRs). …”
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Novel SMAD3 Mutation in a Patient with Hypoplastic Left Heart Syndrome with Significant Aortic Aneurysm by Kristi K. Fitzgerald, Abdul Majeed Bhat, Katrina Conard, James Hyland, Christian Pizarro

“…Family screening for the mutation revealed that his father, who has vascular and skeletal features of AOS, and his brother, who is asymptomatic, also have the pathogenic mutation. This is the first case report of a SMAD3 mutation in a patient with hypoplastic left heart syndrome. …”
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Elizabethkingia anophelis: An uncommon cause of hospital-acquired septic meningitis and a rare cause of community-acquired meningitis in children: A case series by Sarjana Shuchi, Shweta Satija, Manoj B Jais

“…Elizabethkingia is one among several new organisms which heve emerged as an important human pathogen in the past few decades. We present the first two cases of Elizabethkingia anophelis infection reported from our institution. …”
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Post-Harvest Deterioration of Cassava and its Control Using Extracts of Azadirachta Indica and Aframomum Melegueta by R. N. Okigbo, Ramesh Putheti, C. T. Achusi

“…Juss) leaves and Aframomum melegueta (Schumann) seeds were used as antifungal agents and the susceptibility of four of the isolated pathogenic fungi to them was observed in culture. The tested organisms were Aspergillus niger Van Tiegh, Botryodiplodia theobromae Pat, Fusarium solani (Mart). …”
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