Bacterial Blight of Ficus elastica Caused by Xanthomonas by E. Vanessa Campoverde, Aaron J. Palmateer

“…Symptoms somewhat resembled those caused by Xanthomonas campestris p.v. fici, but this pathogen has never been reported to occur on Ficus elastica. …”
Get full text

T-PLL Presenting with an Indolent Course by Arsa Thammahong, Narittee Sukswai, Chantana Polprasert

“…T-cell receptor clonality assessment by next-generation sequencing revealed a dominant clone in the ß-chain constant region. No pathogenic mutations in 25 lymphoma-related genes were found. …”
Get full text

The Bioprospecting of Anti-Vibrio Streptomyces species: Prevalence and Applications by Loh Teng-Hern Tan, Learn-Han Lee, Bey-Hing Goh

“… Vibrio sp. has been a major pathogen that resulted in difficult to treat infections, and greatly impacting the aquaculture industry. …”
Get full text

Impact of heteroresistance on treatment outcomes of people with drug-resistant TB by R. Crowder, M. Kato-Maeda, B. Schwem, A. dela Tonga, D.M. Geocaniga-Gaviola, E. Lopez, C.L. Valdez, A.R. Lim, N. Hunat, A.G. Sedusta, C.A. Sacopon, G.A.M. Atienza, E. Bulag, D. Lim, J. Bascuña, K. Shah, R.P. Basillio, C.A. Berger, M.C.D.P. Lopez, S. Sen, C. Allender, M. Folkerts, U. Karaoz, E. Brodie, S. Mitarai, A.M.C. Garfin, M.C. Ama, D.M. Engelthaler, A. Cattamanchi, R. Destura

Get full text

Diverse biological roles of PhoP/PhoQ in Pseudomonas plecoglossicida: Impact on stress responses and virulence by Meiqin Mao, Li He, Xiangyang Lin, Jianshao Wu, Pan Wang, Chuanzhong Zhu, Qingpi Yan

“…Pseudomonas plecoglossicida is a pathogenic bacterium affecting aquatic animals, responsible for causing a highly fatal disease known as “Visceral White Spot Disease” in various economically important fish species, leading to significant economic losses. …”
Get full text

Probiotic Therapy as an Adjuvant in the Treatment of Periodontal Disease: An Innovative Approach by Liliana Sachelarie, Ioana Scrobota, Ioana Romanul, Raluca Iurcov, Georgiana Ioana Potra Cicalau, Liana Todor

“…<i>Background and Objectives</i>: Periodontal inflammation, often linked to oral microbiota dysbiosis dominated by pathogenic bacteria, remains a significant challenge in periodontitis management. …”
Get full text

Improving the survival under gastric conditions of a potential multistrain probiotic produced in co-culture by Marcelo Fernando Valle-Vargas, Yesica Vanesa Rojas-Muñoz, Ruth Yolanda Ruiz-Pardo, Luisa Villamil-Díaz, María Ximena Quintanilla-Carvajal

“…Our results suggested that was possible to produce a potential multistrain preparation in a lab bioreactor with high viability of L. lactis A12 (9.33 Log10 CFU/mL), high survival to gastric conditions (> 85%), and with antagonistic activity against fish pathogen. This preparation could be used as a feed additive intended for fish nutrition.…”
Get full text

The transcriptional regulator Lrp activates the expression of genes involved in the biosynthesis of tilimycin and tilivalline enterotoxins in Klebsiella oxytoca by Miguel A. De la Cruz, Hilda A. Valdez-Salazar, Diana Rodríguez-Valverde, Santa Mejia-Ventura, Nayely Robles-Leyva, Tania Siqueiros-Cendón, Quintín Rascón-Cruz, Nancy León-Montes, Jorge Soria-Bustos, Fernando Chimal-Cázares, Roberto Rosales-Reyes, María L. Cedillo, Jorge A. Yañez-Santos, J. Antonio Ibarra, Javier Torres, Jorge A. Girón, James G. Fox, Miguel A. Ares

“…Both enterotoxins are non-ribosomal peptides synthesized by enzymes encoded in two divergent operons clustered in a pathogenicity island. The transcriptional regulator Lrp (leucine-responsive regulatory protein) controls the expression of several bacterial genes involved in virulence. …”
Get full text

The cinnamyl alcohol dehydrogenase gene family is involved in the response to Fusarium oxysporum in resistant and susceptible flax genotypes by R. O. Novakovskiy, L. V. Povkhova, G. S. Krasnov, T. A. Rozhmina, A. A. Zhuchenko, L. P. Kudryavtseva, E. N. Pushkova, P. Kezimana, A. V. Kudryavtseva, A. A. Dmitriev, N. V. Melnikova

“…Expression alterations in response to the pathogen were detected for all 13 examined CAD genes. …”
Get full text

Mutation in the COL2A1 gene is associated with acetabular dysplasia by Miaomiao Xin, Xin Guan, Xin Guan, Jiangfei Yang, Yi Li, Zhentao Man, Hongsheng Sun, Min Fu

“…Bioinformatic analysis indicated that the c.823C &gt; T (p.Arg275Cys) variant is pathogenic, and structural modeling demonstrated that the substitution of arginine with cysteine at residue 275 altered the protein structure.ConclusionOur findings highlight the diagnostic utility of NGS in identifying precise genetic causes of DDH. …”
Get full text

Copper Resistance in <i>Pseudomonas syringae</i> pv. <i>actinidiae</i> Strains from the Prefecture of Pella, Northern Greece, and a Comparison of the Effectiveness of Several Comme... by Thomas Thomidis, Marianthi G. Pagoulatou, Eleftherios Alexandridis, Evaggelia Mpalantinaki, Dimitrios E. Goumas

“…<i>actinidiae</i> (<i>Psa</i>), a significant pathogen threatening kiwifruit cultivation globally. …”
Get full text

Skin Microbiota: Mediator of Interactions Between Metabolic Disorders and Cutaneous Health and Disease by Magdalini Kreouzi, Nikolaos Theodorakis, Maria Nikolaou, Georgios Feretzakis, Athanasios Anastasiou, Konstantinos Kalodanis, Aikaterini Sakagianni

“…Similarly, obesity-induced dysregulation of sebaceous lipid composition increases saturated fatty acids, favoring pathogenic strains of <i>Cutibacterium acnes</i>, which produce inflammatory metabolites that exacerbate acne. …”
Get full text

Personalized screening strategies for TP53 R337H carriers: a retrospective cohort study of tumor spectrum in Li-Fraumeni syndrome adult carriersResearch in context by Pedro A.F. Galante, Gabriela D.A. Guardia, Janina Pisani, Renata L. Sandoval, Mateus C. Barros-Filho, Ana Carolina Leite Vieira Costa Gifoni, Diogo F.C. Patrão, Patricia Ashton-Prolla, Vitor Fiorin de Vasconcellos, Claire Freycon, Arnold Levine, Pierre Hainaut, Maria Isabel Achatz

“…Summary: Background: Li-Fraumeni Syndrome (LFS) is a predisposition associated with early onset malignant tumors caused by germline pathogenic variants in the TP53 gene. Although rare worldwide, LFS is prevalent in Southern Brazil due to the founder pathogenic variant R337H. …”
Get full text

Pseudodominant Nanophthalmos in a Roma Family Caused by a Novel PRSS56 Variant by Lubica Dudakova, Pavlina Skalicka, Olga Ulmanová, Martin Hlozanek, Viktor Stranecky, Frantisek Malinka, Andrea L. Vincent, Petra Liskova

“…Sanger sequencing was applied for targeted screening of potentially pathogenic variants and to follow segregation of identified variants within the family. …”
Get full text

Increased Phenotype Severity Associated with Splice-Site Variants in a Hungarian Pediatric Neurofibromatosis 1 Cohort: A Retrospective Study by Klára Veres, Benedek Nagy, Zsófia Ember, Judit Bene, Kinga Hadzsiev, Márta Medvecz, László Szabó, Zsuzsanna Zsófia Szalai

“…<b>Background:</b> Neurofibromatosis type 1 (NF1) is a complex neurocutaneous disorder caused by pathogenic variants in the <i>NF1</i> gene. Although genotype–phenotype correlation studies are increasing, robust clinically relevant correlations have remained limited. …”
Get full text

Six new species of zombie-ant fungi from Yunnan in China by Dexiang Tang, Ou Huang, Weiqiu Zou, Yuanbing Wang, Yao Wang, Quanying Dong, Tao Sun, Gang Yang, Hong Yu

“…This work proposes that the same host of Camponotus can be infected by multiple ant pathogenic fungi, while multiple ants of Polyrhachis can be infected by the same pathogenic fungi at the same time. …”
Get full text

TALome and phenotypic analysis of Pakistani Xanthomonas oryzae pv. oryzae population revealed novel virulent TALEs contributing to bacterial blight of rice by Syed Mashab Ali Shah, Rafia Ahsan, Linlin Liu, Ying Li, Qi Wang, Yong Wang, Jiali Yan, Moein Khojasteh, Xiameng Xu, Zhengyin Xu, Awais Rasheed, Muhammad Zakria, Gongyou Chen

“….; however, Pakistani Xoo TALome diversity and their contribution to pathogenicity is largely unknown. In this study, 101 Xoo strains were screened using specific PCR primers. …”
Get full text

Impact of Soybean Bioactive Peptides on Growth, Lipid Metabolism, Antioxidant Ability, Molecular Responses, and Gut Microbiota of Oriental River Prawn (<i>Macrobrachium nipponense<... by Chang Yang, Bo Liu, Liangkun Pan, Dong Xia, Cunxin Sun, Xiaochuan Zheng, Peng Chen, He Hu, Qunlan Zhou

“…Most importantly, SBPs increased the potential probiotic <i>Rikenellaceae_RC9_gut_group</i> abundance and decreased the abundance of the conditional pathogen <i>Pseudomonas</i> in the gut. In conclusion, SBPs supplementation can improve low-fishmeal-diet-induced growth inhibition by regulating the gut microbiota composition to ameliorate lipid deposition and oxidative stress and strengthen immune status in oriental river prawn.…”
Get full text

Poldip2/Nox4 Mediates Lipopolysaccharide-Induced Oxidative Stress and Inflammation in Human Lung Epithelial Cells by Yueguo Wang, Zhenxing Ding, Youhui Tu, Xu Wu, Wenying Zhang, Shuang Ji, Jilong Shen, Li Zhang, Huimei Wu, Guanghe Fei

Get full text

Chlamydia trachomatis Growth and Cytokine mRNA Response in a Prostate Cancer Cell Line by Ivan M. Petyaev, Naylia A. Zigangirova, Elena Y. Morgunova, Nigel H. Kyle, Elena D. Fedina, Yuriy K. Bashmakov

“…It was shown that the infectious cycle of chlamydial pathogen in CWR-R1 cells resembles the progression of C. trachomatis infection in McCoy cells but with a few important differences. …”
Get full text