Potential of Pine Biochar to Mitigate Bacterial Hazards Present in Recycled Manure Solids from Dairy Cows by Ana José Pires, Ana Filipa Esteves, Gonçalo Pereira, Catarina Geraldes, Joana Fernandes Guerreiro, Raquel Abreu, Rita Magalhães, Lélia Chambel, Elisabete Silva, David Fangueiro, Manuela Oliveira, Ricardo Bexiga

“…Overall, there were no significant changes in the isolates’ virulence or resistance profiles, and none of the isolates obtained were classified as high or moderate threats based on their MAR and VIR indexes. The most pathogenic <i>Enterococcus</i> isolates found were present in the control samples. …”
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Deoxycholic Acid Could Induce Apoptosis and Trigger Gastric Carcinogenesis on Gastric Epithelial Cells by Quantitative Proteomic Analysis by Yanyan Shi, Ying Wei, Ting Zhang, Jing Zhang, Ye Wang, Shigang Ding

“…These findings may improve the understanding of the molecular mechanisms underlying the pathogenicity of bile acids on gastric mucosa.…”
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Genetically-encoded targeted protein degradation technology to remove endogenous condensation-prone proteins and improve crop performance by Ming Luo, Sitao Zhu, Hua Dang, Qing Wen, Ruixia Niu, Jiawei Long, Zhao Wang, Yongjia Tong, Yuese Ning, Meng Yuan, Guoyong Xu

“…Additionally, conditional degradation of the negative defense regulator Early Flowering 3 via a pathogen-responsive ProTBF1-uORFsTBF1 cassette enhances rice blast resistance without affecting flowering time in the absence of pathogen. …”
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Overview of Recent Advances in Canine Parvovirus Research: Current Status and Future Perspectives by Hongzhuan Zhou, Kaidi Cui, Xia Su, Huanhuan Zhang, Bing Xiao, Songping Li, Bing Yang

“…It is globally recognized as a highly contagious and lethal pathogen. CPV is prone to rapid mutation, leading to the emergence of new variants. …”
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In vitro inhibition mechanisms of Trichoderma yunnanense TM10 against Pyricularia oryzae and Rhizoctonia solani causing blast and sheath blight diseases in rice (Oryza sativa L.) by Dedat Prismantoro, Thomas Argyarich Jefferson, Sulistya Ika Akbari, Mia Miranti, Muhamad Shakirin Mispan, Febri Doni

“…In this study, we investigated the antagonistic potential of the local isolate Trichoderma yunnanense TM10 against the pathogenic fungi P. oryzae and R. solani. The results demonstrated that T. yunnanense TM10 inhibited the growth of P. oryzae and R. solani through mechanisms such as competition, mycoparasitism, and antibiosis. …”
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Genetic Etiology of Ichthyosis in Turkish Patients: Next-generation Sequencing Identified Seven Novel Mutations by Hanife SAAT, Ibrahim SAHIN, Neslihan DUZKALE, Muzeyyen GONUL, Taha BAHSI

“…Results: Sixteen likely pathogenic or pathogenic variants were detected in 13 unrelated patients. …”
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Dual mechanisms of G3 against Vibrio parahaemolyticus in shrimp aquaculture by Cuixia Chen, Yangyang Ge, Qilong Gu, Tianling Wang, Yanyan Yang, Jinpeng Hu, Kang Gao, Xing Zhou, Hui Li

“…However, their anti-Vibrio mechanisms have not yet reached a consensus. In this study, a pathogenic Vibrio strain was isolated from the cultured shrimp and was identified as Vibrio parahaemolyticus UPC-1 (V. …”
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Investigation of the optimal condition for the growth and biofilm development of Candida albicans on three dental materials by Hoai Thu Le, Truong Thi Luc Phuong, Giang Hoang Huy, Phuoc-Vinh Nguyen, Bac Vu Giang Nguyen

“… Background and Objectives: Candida albicans as pathogenic fungi cause conditions like oral candidiasis and dental caries. …”
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S. gallolyticus Aortic Valve Endocarditis with Mitral Valve Leaflet Aneurysm by S. Poddi, I. Tropea, G. Faggian, S. De Feo, M. Zordan, A. Rungatscher

“…S. gallolyticus is one of the pathogenic agents of endocarditis, and mitral valve aneurysm is a rare but potentially devastating complication. …”
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Decoding the anomalies: a genome-based analysis of Bacillus cereus group strains closely related to Bacillus anthracis by Thuto Gomolemo Magome, Marius Surleac, Marius Surleac, Ayesha Hassim, Cornelius Carlos Bezuidenhout, Henriette van Heerden, Kgaugelo Edward Lekota

“…IntroductionThe Bacillus cereus group encompasses a complex group of closely related pathogenic and non-pathogenic bacterial species. Key members include B. anthracis, B. cereus, and B. thuringiensis organisms that, despite genetic proximity, diverge significantly in morphology and pathogenic potential. …”
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Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway by Xin Ma, Meng Li, Yuanyuan Zhang, Tingting Xu, Xinchen Zhou, Mengqi Qian, Zhiren Yang, Xinyan Han

“…As the largest mucosal surface, the gut has built a physical, chemical, microbial, and immune barrier to protect the body against pathogen invasion. The disturbance of gut microbiota aggravates pathogenic bacteria invasion and gut barrier injury. …”
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Analysis of mutations in CDC27, CTBP2, HYDIN and KMT5A genes in carotid paragangliomas by E. N. Lukyanova, A. V. Snezhkina, D. V. Kalinin, A. V. Pokrovsky, A. L. Golovyuk, O. A. Stepanov, E. A. Pudova, G. S. Razmakhaev, M. V. Orlova, A. P. Polyakov, M. V. Kiseleva, A. D. Kaprin, A. V. Kudryavtseva

“…Thus, there is a necessity to improve the methods for identification of cancer-asso ciated genes as well as pathogenic mutations.…”
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Predicting the Most Deleterious Missense Nonsynonymous Single-Nucleotide Polymorphisms of Hennekam Syndrome-Causing CCBE1 Gene, In Silico Analysis by Khyber Shinwari, Liu Guojun, Svetlana S. Deryabina, Mikhail A. Bolkov, Irina A. Tuzankina, Valery A. Chereshnev

“…Using state-of-the-art in silico tools, this study examined the most pathogenic nonsynonymous single-nucleotide polymorphisms (nsSNPs) that disrupt the CCBE1 protein and extracellular matrix remodeling and migration. …”
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Combined mutations in nonstructural protein 14, envelope, and membrane proteins mitigate the neuropathogenicity of SARS-CoV-2 Omicron BA.1 in K18-hACE2 mice by Kotou Sangare, Shufeng Liu, Prabhuanand Selvaraj, Charles B. Stauft, Matthew F. Starost, Tony T. Wang

“…Here, we assessed the pathogenicity of SARS-CoV-2 (WA1/2020) containing mutations from the Omicron BA.1 variant in K18-hACE2 mice. …”
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Neutralizing antibody responses to three XBB protein vaccines in older adults by Guo-Jian Yang, Mei Lu, Rui-Rui Chen, Shuang-Qing Wang, Sheng Wan, Xue-Dong Song, Guo-Ping Cao, Lei Lv, Xue-Juan He, Bing-Dong Zhan, Mai-Juan Ma

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Annosum Root Rot of Southern Pines by Tyler Dreaden, Jason Smith

“…FOR269, a 3-page illustrated fact sheet by Tyler Dreaden and Jason Smith, describes this damaging forest pathogen that infects a wide range of species, including southern pine, and can cause tree mortality, reduced growth rates, susceptibility to attack by bark beetles, and regeneration failure. …”
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Annosum Root Rot of Southern Pines by Tyler Dreaden, Jason Smith

“…FOR269, a 3-page illustrated fact sheet by Tyler Dreaden and Jason Smith, describes this damaging forest pathogen that infects a wide range of species, including southern pine, and can cause tree mortality, reduced growth rates, susceptibility to attack by bark beetles, and regeneration failure. …”
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Crystal structure of (E)-7-fluoro-2-(4-fluorobenzylidene)-3,4-dihydronaphthalen-1(2H)-one, C17H12F2O by Wei Pan-Pan, Meng Qing-Guo, Wang Bao-Gang, Hou Gui-Ge, Song Ya-Bin

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Therapies for Mitochondrial Disorders by Kayli Sousa Smyth, Anne Mulvihill

“…MTDS are clinical syndromes coupled with abnormalities of the ETC and OXPHOS, caused by pathogenic variants in mtDNA or nDNA. Many MTDS emerge from either homoplasmic or heteroplasmic mutations of the DNA, and include mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes. …”
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Nature of viruses and the radical change in viral taxonomy by V. V. Makarov, L. P. Buchatsky

“…The metagenomic sequencing has revealed the presence of a vast variety of viruses in diverse environmental samples without any connections with banal parasitism, infectivity, or pathogenicity. The understanding of viruses has expanded beyond the original parasitic–pathogen model, and now virologists recognize the role of viruses in host regulation and the maintenance of natural ecosystems. …”
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