Discovery of a Novel Shared Variant Among RTEL1 Gene and RTEL1-TNFRSF6B lncRNA at Chromosome 20q13.33 in Familial Progressive Myoclonus Epilepsy by Sima Chaudhari, Lavanya Prakash Acharya, Dushyanth Babu Jasti, Akshay Pramod Ware, Sankar Prasad Gorthi, Kapaettu Satyamoorthy

“…These genes when characterized fully may shed light on pathogenicity and have the potential to be used in the diagnosis of PME.…”
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In vivo antifungal activity of neem oil and aqueous extracts against leaf spot disease caused by <i>Cercospora abelmoschii</i> on okra by Aricléia De Moraes Catarino, Antonia Alice Costa Rodrigues, João Victor Jansen De Queiroz, Luciano Marinho Furtado, Leilson Lopes Santos Silva Silva

“…The extracts and neem oil were tested in concentration 10%, the fungicide cercobin 700PM® in dose 2.5 g.l-1, applied 10 days after pathogen inoculation by leaf spray and the citric biomass extract ecolife® in concentration 5.0 ml.l-1, applied 10 days before pathogen inoculation. …”
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Beta-Defensin-2 and Beta-Defensin-3 Reduce Intestinal Damage Caused by Salmonella typhimurium Modulating the Expression of Cytokines and Enhancing the Probiotic Activity of Enteroc... by Alessandra Fusco, Vittoria Savio, Marcella Cammarota, Alberto Alfano, Chiara Schiraldi, Giovanna Donnarumma

“…If this healthy microbiota is disrupted by antibiotics, chemotherapy, or a change in diet, intestinal colonization by pathogenic bacteria or viruses may occur, leading to disease. …”
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Intravitreal Ampicillin Sodium for Antibiotic-Resistant Endophthalmitis: Streptococcus uberis First Human Intraocular Infection Report by Raul Velez-Montoya, Dulce Rascón-Vargas, William F. Mieler, Jans Fromow-Guerra, Virgilio Morales-Cantón

“…To describe the clinical characteristics, diagnosis, and treatment with intravitreal ampicillin sodium of a postoperative endophthalmitis case due to Streptococcus uberis; an environmental pathogen commonly seen in mastitis cases of lactating cows. …”
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Multiple blood feeding bouts in mosquitoes allow for prolonged survival and are predicted to increase viral transmission during dry periods by Christopher J. Holmes, Souvik Chakraborty, Oluwaseun M. Ajayi, Melissa R. Uhran, Ronja Frigard, Crystal L. Stacey, Emily E. Susanto, Shyh-Chi Chen, Jason L. Rasgon, Matthew DeGennaro, Yanyu Xiao, Joshua B. Benoit

“…Overall, these results solidify our understanding of how dry periods impact mosquito blood feeding and the role that mosquito dehydration contributes to pathogen transmission dynamics.…”
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Irritable bowel syndrome: pathophysiological and clinical issues by V. T. Ivashkin, Ye. A. Poluektova

“…Treatment of patients will allow to optimize further investigations of certain etiological, pathogenic factors, to carry out differential diagnostics of IBS more clearly.…”
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Pitfalls in Genetic Testing for Consanguineous Pediatric Populations by Maha Saleh, Samantha Colaiacovo, Melanie P. Napier, Asuri N. Prasad, C. Anthony Rupar, Chitra Prasad

“…The first was a homozygous pathogenic HERC2 gene partial deletion of exons 43–45 that causes HERC2-related disorder. …”
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In vivo antifungal activity of neem oil and aqueous extracts against leaf spot disease caused by <i>Cercospora abelmoschii</i> on okra by Aricléia De Moraes Catarino, Antonia Alice Costa Rodrigues, João Victor Jansen De Queiroz, Luciano Marinho Furtado, Leilson Lopes Santos Silva Silva

“…The extracts and neem oil were tested in concentration 10%, the fungicide cercobin 700PM® in dose 2.5 g.l-1, applied 10 days after pathogen inoculation by leaf spray and the citric biomass extract ecolife® in concentration 5.0 ml.l-1, applied 10 days before pathogen inoculation. …”
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Mechanisms of bacterial-to-host interaction and their disorders at inflammatory bowel diseases by Ye. A. Poluektova, O. S. Lyashenko, A. V. Korolev, O. S. Shifrin, V. T. Ivashkin

“…Disorder of barrier function of intestine at IBD patients, in combination to prevalence of opportunistic and pathogenic microorganisms in intestinal biome, results in essential overload of innate and adaptive immune system.Conclusion. …”
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Unwanted disorders and xenogeneic graft‐versus‐host disease in experimental immunodeficient mice: How to evaluate and how to report by Seyed Mostafa Monzavi, Samad Muhammadnejad, Vahid Mansouri, Hami Ashraf, Naser Ahmadbeigi

“…Therefore, a rigorous health surveillance and clinical monitoring system, along with the establishment of a strictly controlled barrier facility to maintain a pathogen‐free state, are mandatory. Even if all pathogen control and biosafety measures are followed, there are various noninfectious disorders capable of causing tissue and multiorgan damage in immunodeficient animals. …”
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An Unusual Case of Streptococcus anginosus Group Pyomyositis Diagnosed Using Direct 16S Ribosomal DNA Sequencing by Andrew Walkty, John M Embil, Kim Nichol, James Karlowsky

“…It also highlights the potential utility of 16S ribosomal DNA amplification and sequencing in direct pathogen detection from aspirated fluid in cases of pyomyositis in which antimicrobial therapy was initiated before specimen collection.…”
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Isolation of a New Mexican Strain of Bacillus subtilis with Antifungal and Antibacterial Activities by M. G. L. Basurto-Cadena, M. Vázquez-Arista, J. García-Jiménez, R. Salcedo-Hernández, D. K. Bideshi, J. E. Barboza-Corona

“…In addition, B. subtilis 21 showed activity against pathogenic bacteria. Secreted proteins by B. subtilis 21 were studied, detecting the presence of proteases and bacteriocin-like inhibitor substances that could be implicated in its antagonistic activity. …”
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Potential Usefulness of Streptococcus pneumoniae Extracellular Membrane Vesicles as Antibacterial Vaccines by Chi-Won Choi, Edmond Changkyun Park, Sung Ho Yun, Sang-Yeop Lee, Seung Il Kim, Gun-Hwa Kim

“…Although the S. pneumoniae bacteria were highly pathogenic in a mouse model, the EMVs purified from these bacteria showed low pathological activity both in cell culture and in mice. …”
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Nutritional support in early phases of acute pancreatitis: fashionable trend and essential reality by Ye. Ye. Achkasov, A. V. Pugayev, G. V. Dyatchina, V. I. Posudnevsky, Zh. G. Nabiyeva, P. V. Melnikov

“…It was demonstrated, that from the pathogenic point of view total parenteral nutrition is most justified in the phase of enzyme toxemia and intermediate phase of AP for 7 to 14 days and more in relation to the initial prognosis of disease severity. …”
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Chlamydia Pneumoniae Pneumonia: An Evolving Clinical Spectrum by David Megran, Rosanna W Peeling, Thomas J Marrie

“…Chlamydia pneumoniae is a recently recognized respiratory tract pathogen. It accounts for 6 to 10% of all cases of community acquired pneumonia requiring admission to hospital. …”
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Th1 and Th17 Cells in Tuberculosis: Protection, Pathology, and Biomarkers by I. V. Lyadova, A. V. Panteleev

“…The outcome of Mycobacterium tuberculosis (Mtb) infection ranges from a complete pathogen clearance through asymptomatic latent infection (LTBI) to active tuberculosis (TB) disease. …”
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Metabolomic Analysis of Key Regulatory Metabolites in the Urine of Flavivirus-Infected Mice by Xiaoyan Zheng, Ran Wang

“…Different flaviviruses exhibit different biological characteristics and pathogenicity. Metabolomics is an emerging research perspective to uncover and observe the pathogenesis of certain infections. …”
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Standardized Surgical Management for Cystic Dilation of the Bile Ducts Based on Clinical and Pathological Studies: A Narrative Review by Hong-Tian Xia

“…In recent years, significant progress has been made in understanding the pathogenic mechanism and pathological changes of adult CDBDs. …”
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Recommendations for Control and Mitigation of Laurel Wilt and Ambrosia Beetle Vectors in Commercial Avocado Groves in Florida by Jonathan Henry Crane, Daniel Carrillo, Edward A. Evans, Romina Gazis, Bruce A Schaffer, Fredy H Ballen Orozco, Jeff Wasielewski

“… The lethal laurel wilt epidemic affecting avocado trees in Florida is caused by a fungal pathogen-ambrosia beetle complex (LW-AB). The death of over 120,000 commercial avocado trees in Florida may be attributed to LW-AB. …”
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Association of p53 with Neurodegeneration in Parkinson’s Disease by Qiang Luo, Wei Sun, Yi-Fan Wang, Ji Li, Da-Wei Li

“…Pathogenic p53 integrates diverse cellular stresses and activate these downstream events to induce the degeneration of dopaminergic neurons; thus, it plays a crucial role in the pathogenesis of PD and appears to be a potential target for the treatment of the disease. …”
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