Isolation of a Novel Caprine <i>Eimeria christenseni</i> Strain (GC) in Canary Islands and Analysis of Parasitological, Clinical, and Pathological Findings on Experimentally Infect... by Emilio Barba, José Manuel Molina, Francisco Rodríguez, Otilia Ferrer, María Carmen Muñoz, Liliana M. R. Silva, María Cristina Del Río, José Adrián Molina, Anja Taubert, Carlos Hermosilla, Antonio Ruiz

“…<i>Eimeria christenseni</i> is considered among the most pathogenic <i>Eimeria</i> species in goats. The aim of this study was to isolate an <i>E. christenseni</i> strain and to assess its infectivity, pathogenicity, and ability to develop a protective immune response. …”
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Existence of Traveling Wave Solutions for Cholera Model by Tianran Zhang, Qingming Gou, Xiaoli Wang

“…To investigate the spreading speed of cholera, Codeço’s cholera model (2001) is developed by a reaction-diffusion model that incorporates both indirect environment-to-human and direct human-to-human transmissions and the pathogen diffusion. The two transmission incidences are supposed to be saturated with infective density and pathogen density. …”
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Wilson disease (novel ATP7B variants) with concomitant FLNC-related cardiomyopathy by Takeshi Imai, Satomi Mitsuhashi, Kenji Isahaya, Soichiro Shibata, Yosuke Kawai, Yosuke Omae, Katsushi Tokunaga, NCBN Controls WGS Consortium, Yoshihisa Yamano

“…Abstract We report a case of Wilson disease (WD) with dilated cardiomyopathy in which whole-genome sequencing (WGS) revealed the rare co-occurrence of two novel compound heterozygous ATP7B pathogenic variants (NM_001005918.3:c.2250del/p.N751Tfs*9 and c.3496C>T/p.L1166F) and a known FLNC pathogenic variant. …”
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Single‐cell sequencing reveals the features of adaptive immune responses in the liver of a mouse model of dengue fever by Yizhen Yuan, Qian Chen, Zhe Li, Fangzhou Cai, Dan Li, Wei Wang

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Genetic variation reveals the therapeutic potential of BRSK2 in idiopathic pulmonary fibrosis by Zhe Chen, Mingyang Tang, Nan Wang, Jiangjiang Liu, Xiaoyan Tan, Haitao Ma, Jing Luo, Kai Xie

“…Abstract Background Current research underscores the need to better understand the pathogenic mechanisms and treatment strategies for idiopathic pulmonary fibrosis (IPF). …”
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Polydomus karssenii gen. nov. sp. nov. is a dark septate endophyte with a bifunctional lifestyle parasitising eggs of plant parasitic cyst nematodes (Heterodera spp.) by Samad Ashrafi, Jan-Peer Wennrich, Yvonne Becker, Jose G. Maciá-Vicente, Anke Brißke-Rode, Matthias Daub, Torsten Thünen, Abdelfattah A. Dababat, Maria R. Finckh, Marc Stadler, Wolfgang Maier

“…The strains were found to represent a distinct phylogenetic lineage most closely related to Equiseticola and Ophiosphaerella, and Polydomus karssenii (Phaeosphaeriaceae, Pleosporales) is introduced here as a new species representing a monotypic genus. The pathogenicity tests against nematode eggs fulfilled Koch’s postulates using in vitro nematode bioassays and showed that the fungus could parasitise its original nematode host H. filipjevi as well as the sugar beet cyst nematode H. schachtii, and colonise cysts and eggs of its hosts by forming highly melanised moniliform hyphae. …”
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Combination of Human Leukocyte Antigen and Killer Cell Immunoglobulin-Like Receptor Genetic Background Influences the Onset Age of Hepatocellular Carcinoma in Male Patients with He... by Ning Pan, Jie Qiu, Hang Sun, Fengqin Miao, Qian Shi, Jinhuan Xu, Wei Jiang, Hui Jin, Wei Xie, Youji He, Jianqiong Zhang

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Occurrence of Spot Blotch in Spring Barley Caused by Bipolaris sorokiniana Shoem. in South-Eastern Kazakhstan by Yerlan Dutbayev, Nurlan Kuldybayev, Saule Daugaliyeva, Elvira Ismailova, Nadira Sultanova, Göksel Özer, Ayana Slyamova, Kadyrzhan Mukin, Abdelfattah Dababat, Minura Yessimbekova

“…Pathogenicity of B. sorokiniana isolates was made on barley seedlings in vitro. …”
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When a sore throat turns into deadly multiple serous cavity effusions: the role of Prevotella oris in rapidly progressing infection—a case report by Fangqi Zhang, Juan-Li Wang, Jian Zhu, Shaokui Si, Hao Guo, Xiang Yue, Wei Wen

“…After multiple cultures of the patient’s sputum yielded no identifiable pathogenic bacteria, the metagenomic next-generation sequencing (mNGS) revealed Prevotella oris as the predominant pathogen present in both the patient’s peripheral blood and the pericardial drainage fluid. …”
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Porphyromonas gulae and canine periodontal disease: Current understanding and future directions by Kyu Hwan Kwack, Eun-Young Jang, Cheul Kim, Young-Suk Choi, Jae-Hyung Lee, Ji-Hoi Moon

“…Porphyromonas gulae has emerged as a notable pathogen in canine periodontal disease, akin to Porphyromonas gingivalis in human periodontitis. …”
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Molecular genetic analysis of Rubinstein–Taybi syndrome in Russian patients by Olga R. Ismagilova, Tagui A. Adyan, Tagui A. Adyan, Tatiana S. Beskorovainaya, Alexander V. Polyakov

“…Nevertheless, for approximately half of the patients in various cohorts, the diagnosis cannot be confirmed.MethodsIn this paper we present the results of a study of 158 Russian patients referred for molecular diagnosis of RSTS using multiplex ligation-dependent probe amplification (MLPA) and next-generation sequencing (NGS).ResultsPathogenic and likely pathogenic variants were identified in 67 patients (42.4%), of which 62 (39%) were in CREBBP and 4 cases (2%)—in EP300. …”
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A comprehensive review on elucidating the host disease resistance mechanism from the perspective of the interaction between cotton and Verticillium dahliae by Yalin Zhang, Lihong Zhao, Dongpo Li, Ziming Li, Hongjie Feng, Zili Feng, Feng Wei, Jinglong Zhou, Zhiying Ma, Jun Yang, Heqin Zhu

“…Abstract Verticillium wilt, caused by the infamous pathogen Verticillium dahliae, presents a primary constraint on cotton cultivation worldwide. …”
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GJB6-D13S1830 and GJB6-D13S1854 Deletions in Patients with non-Syndromic Prelingual Deafness by Mercedes Arceo Álvarez, Estela Morales Peralta, Yuledmi Perdomo Chacón, Teresa Collazo Mesa

“…These deletions have been found associated with pathogenic variants of the GJB2 gene in individuals with hearing loss. …”
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The Role of Long-Chain Fatty Acids in Inflammatory Bowel Disease by Chunxiang Ma, Reshma Vasu, Hu Zhang

“…Inflammatory bowel disease (IBD) is a complicated disease involving multiple pathogenic factors. The complex relationships between long-chain fatty acids (LCFAs) and the morbidity of IBD drive numerous studies to unravel the underlying mechanisms. …”
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A novel NFKB1 variant in a Japanese pedigree with common variable immunodeficiency by Naoko Nakatani, Akihiro Tamura, Hiroaki Hanafusa, Nanako Nino, Nobuyuki Yamamoto, Hiroyuki Awano, Yasuhiro Tanaka, Naoya Morisada, Suguru Uemura, Atsuro Saito, Daiichiro Hasegawa, Kandai Nozu, Yoshiyuki Kosaka

“…Her mother and daughter carried the same variant, demonstrating the first Japanese pedigree with an NFKB1 pathogenic variant.…”
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CROP ALERT: A Citrus Canker Fact Sheet for Homeowners by H. L. Chamberlain, Pamela D. Roberts, Lavern W. Timmer, Kuang-Ren Chung, Mongi Zekri

“… Citrus canker (CC) is caused by the bacterial pathogen Xanthomonas axonopodis pv. citri. The pathogen enters host tissues through wounds and natural openings called stomata. …”
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Western Leaffooted Bug Leptoglossus zonatus (Dallas) (Insecta: Hemiptera: Coreidae) by Amelio A. Chi, Russell F. Mizell

“…It transmits a trypanosomatid plant pathogen similar to the one that causes Chagas’ disease and sleeping sickness in humans, but that is only pathogenic to plants. …”
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CROP ALERT: A Citrus Canker Fact Sheet for Homeowners by H. L. Chamberlain, Pamela D. Roberts, Lavern W. Timmer, Kuang-Ren Chung, Mongi Zekri

“… Citrus canker (CC) is caused by the bacterial pathogen Xanthomonas axonopodis pv. citri. The pathogen enters host tissues through wounds and natural openings called stomata. …”
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Western Leaffooted Bug Leptoglossus zonatus (Dallas) (Insecta: Hemiptera: Coreidae) by Amelio A. Chi, Russell F. Mizell

“…It transmits a trypanosomatid plant pathogen similar to the one that causes Chagas’ disease and sleeping sickness in humans, but that is only pathogenic to plants. …”
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Antimicrobial Activities of Stigmasterol from Piper crocatum In Vitro and In Silico by Seftiana Lestari, Dikdik Kurnia, Tri Mayanti, Leny Heliawati

“…Therefore, it can be inferred that the stigmasterol present in Red Betel leaves could potentially function as an antimicrobial agent by impeding the spread of pathogenic oral microorganisms.…”
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