Differential Immunogenicity and Protective Efficacy Elicited by MTO- and DMT-Adjuvanted CMFO Subunit Vaccines against Mycobacterium tuberculosis Infection by Nadeem Ullah, Ling Hao, Yaqi Wu, Yandi Zhang, Qing Lei, Jo-Lewis Banga Ndzouboukou, Xiaosong Lin, Xionglin Fan

“…Proper selection of the delivery system for the vaccine is crucial for inducing an appropriate immune response tailored to control the target pathogen. In this study, we compared the immunogenicity and protective efficacy of CMFO subunit vaccines against primary progressive TB in two different adjuvant systems: the MTO oil-in-water (O/W) emulsion composed of monophosphoryl lipid A (MPL), trehalose-6,60-dibehenate (TDB), and oil in water emulsion MF59 and the DMT liposome containing dimethyldioctadecylammonium bromide (DDA), monophosphoryl lipid A (MPL), and trehalose-6,60-dibehenate (TDB). …”
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Temperature-dependent variations in under-canopy herbaceous foliar diseases following shrub encroachment in grasslands by Yilin Dang, Peng Zhang, Peixi Jiang, Junsheng Ke, Yao Xiao, Yingying Zhu, Mu Liu, Minjie Li, Jihua Wu, Jianquan Liu, Bin Tian, Xiang Liu

“…Disparities in herbaceous biomass between shrub and grassland patches elucidate changes in pathogen load. In colder regions, shrub encroachment diminishes herbaceous biomass and pathogen load. …”
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Biological control of bacterial leaf blight (BLB) in rice–A sustainable approach by Bestha Sai Teja, Gayatri Jamwal, Vishal Gupta, Mansi Verma, Ayushi Sharma, Akash Sharma, Vinod Pandit

“…Bacterial leaf blight (BLB) in rice, caused by the pathogen Xanthomonas oryzae pv. oryzae, is a significant agricultural problem managed through chemical control and cultivating rice varieties with inherent resistance to the bacterial pathogen. …”
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Aloe-Emodin-Mediated Photodynamic Therapy Induces Apoptosis in Basal Cell Carcinoma Cells via Activation of ERK/JNK Signaling Pathway by Woodvine Otieno Odhiambo, Songmei Geng, Xiaopeng Wang, Xiaodong Chen, Mengting Qin, Meng Yuan, Yang Wang, Farooq Riaz, Chengcheng Liu, Yanhong Ji

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Leveraging genomic insights from the neglected malaria parasites P. malariae and P. ovale using selective whole genome amplification (SWGA) approach by Fathia Ben-Rached, Amit Kumar Subudhi, Chang Li, Mariah Alawi, Rohit Satyam, Sui Xu, Guoding Zhu, Raeece Naeem, Sara Mfarrej, Di Liu, Zenaida Stead, Caroline Askonas, Yaobao Liu, Jun Cao, Arnab Pain

“…Results We applied SWGA using specifically designed primer sets targeting the pathogen genome to enrich parasite DNA from clinical samples. …”
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Epidemiology and Ecology of Toscana Virus Infection and Its Global Risk Distribution by Xue-Geng Hong, Mei-Qi Zhang, Fang Tang, Si-Hui Song, Jia-Yi Wang, Zhen-Yu Hu, Li-Ming Liu, Xiao-Ai Zhang, Yi Sun, Li-Qun Fang, Wei Liu

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Functional Verification of Differentially Expressed Genes Following DENV2 Infection in <i>Aedes aegypti</i> by Xiaoli Chen, Xinyu Zhou, Xiaoxue Xie, Bo Li, Teng Zhao, Haotian Yu, Dan Xing, Jiahong Wu, Chunxiao Li

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The Expression of IL-6, TNF-α, and MCP-1 in Respiratory Viral Infection in Acute Exacerbations of Chronic Obstructive Pulmonary Disease by Jingtong Zheng, Yue Shi, Lingxin Xiong, Weijie Zhang, Ying Li, Peter G. Gibson, Jodie L. Simpson, Chao Zhang, Junying Lu, Jingying Sai, Guoqiang Wang, Fang Wang

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A TaqMan Real-Time PCR Assay for Detection and Quantification of Sporisorium scitamineum in Sugarcane by Yachun Su, Shanshan Wang, Jinlong Guo, Bantong Xue, Liping Xu, Youxiong Que

“…This assay was capable of detecting the smut pathogen at the initial stage (12 h) of infection and suitable for inspection of sugarcane pathogen-free seed cane and seedlings. …”
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The Role and Function of Regulatory T Cells in Toxoplasma gondii-Induced Adverse Pregnancy Outcomes by Xuyang Gao, Yue Zhong, Yifan Liu, Runmin Ding, Jinling Chen

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Purpurin suppresses Salmonella invasion of host cells by reducing the secretion of T3SS-1 effector proteins by Zhenxu Shi, Zhimin Guo, Siqi Li, Chenxiao Jiang, Jianfeng Wang, Xuming Deng, Hongtao Liu, Jiazhang Qiu

“…Typhimurium, ST) is a food-borne pathogen that can be transmitted from animals to humans and causes symptoms such as diarrhea, fever, and vomiting. …”
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Prevalence and molecular characterization of Enterocytozoon bieneusi in endangered Eld’s deer (Rucervus eldii) in Hainan, China by Yun Zhang, Yun Zhang, Guangxu Ren, Guangxu Ren, Qingqing Lu, Jiaqi Li, Jiaqi Li, Yu Qiang, Youyou Li, Xiuyi Lai, Yuan Wang, Xingyue Yu, Sheng Lei, Yu Li, Yunxing Chang, Xianrong Liu, Xuning Qi, Zhi Xie, Tingting Li, Jiang Du, Rui Duan, Xinyu Chang, Hesheng Wang, Hesheng Wang, Gang Lu, Gang Lu

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Diagnostic Value of Microarray Method in Autism Spectrum Disorder, Intellectual Disability, and Multiple Congenital Anomalies and Some Candidate Genes for Autism: Experience of Two... by Akif AYAZ, Alper GEZDIRICI, Elif YILMAZ GULEC, Özge OZALP, Abdullah Huseyin KOSEOGLU, Zeynep DOGRU, Sinem YALCINTEPE

“…Pathogenic or likely pathogenic CNVs were detected in 61 (13.6%) of 445 patients. …”
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Occurrence and Multi-Locus Genotyping of <i>Giardia duodenalis</i> in Black Goats from Fujian Province, China by Shou-Xiao Huang, Kai Hu, Peng-Fei Fu, Si-Ang Li, Yang Liu, Zhipeng Niu, Dong-Hui Zhou

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SMARCA4-related Coffin-Siris syndrome in newborn: a case report and literature review by Yuqian Wang, Li Zhang, Jing Zhu, Liu Yang, Chan Wang, Ning Zou

“…Parents did not find the above pathogenic variant, which was a new pathogenic variant. …”
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Cannabidiol attenuates lipid metabolism and induces CB1 receptor-mediated ER stress associated apoptosis in ovarian cancer cells by Xuanhe Fu, Zhixiong Yu, Fang Fang, Weiping Zhou, Yuxin Bai, Zhongjia Jiang, Biao Yang, Ye Sun, Xing Tian, Guangyan Liu

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The PHD transcription factor Cti6 is involved in the fungal colonization and aflatoxin B1 biological synthesis of Aspergillus flavus by Zhang Mengjuan, Lin Guanglan, Pan Xiaohua, Song Weitao, Tan Can, Chen Xuan, Yang Yanling, Zhuang Zhenhong

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Helicobacter pylori reduces METTL14-mediated VAMP3 m6A modification and promotes the development of gastric cancer by regulating LC3C-mediated c-Met recycling by Xixi Cui, Mingjie Chang, Yuqiong Wang, Jiayi Liu, Zenghui Sun, Qiyu Sun, Yundong Sun, Juchao Ren, Wenjuan Li

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The History of Methicillin-Resistant Staphylococcus aureus in Brazil by Mariana Moreira Andrade, Wilson Barros Luiz, Rayane da Silva Oliveira Souza, Jaime Henrique Amorim

“…Clinical manifestations may vary from brand to critical condition due to host risk factors, as well as pathogen virulence and resistance. The high adaptability and pathogenic profile of MRSA clones contributed to its spread in hospital and community settings. …”
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A strategy for controlling Hypervirulent Klebsiella pneumoniae: inhibition of ClpV expression by Wenke Liu, Dan Wang, Qiangxing He, Shiwen Cao, Jiaxin Cao, Huajie Zhao, Junwei Cui, Fan Yang

“…In the present study, the clpV gene deletion strain of hvKP (ΔclpV-hvKP) was constructed using CRISPR-Cas9 technology, and the biological characteristics of ΔclpV-hvKP were investigated to explore the new targets for controlling this pathogen. The results showed that clpV gene deletion did not affect the growth ability of hvKP. …”
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