Showing 161 - 180 results of 3,743 for search '"pathogenesis"', query time: 0.05s Refine Results
  1. 161

    Oxidative stress and dysregulated long noncoding RNAs in the pathogenesis of Parkinson’s disease by Jialu Wang, Meitong Liu, Jiuhan Zhao, Pan Hu, Lianbo Gao, Shen Tian, Jin Zhang, Huayan Liu, Xiaoxue Xu, Zhenwei He

    Published 2025-01-01
    “…This review discusses the general mechanisms of oxidative stress, pathological mechanism underlying the role of oxidative stress in the pathogenesis of PD, and teases out the mechanisms through which lncRNAs regulate oxidative stress during PD pathogenesis, as well as identifies the possible neuroprotective mechanisms of lncRNAs. …”
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    Investigation of the Potential Roles of Thyroid Gland Hormones in the Pathogenesis of Thyroid Disorders by Enas Sobeih, Mohammed .Alwan, Arwa Hussein, Ali Abd Almuna'am

    Published 2024-12-01
    “…This study was designed to evaluate the roles of total Thyroxine T4, total T3, free Thyroxine FT4, free triiodothyronine FT3, and thyroid stimulating hormone TSH indicators in the pathogenesis of patients with thyroid diseases. Seventy patients with thyroid diseases and thirty healthy individuals (as a control group) were enrolled in this study from April to July 2024. …”
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    Genetic insight into dissecting the immunophenotypes and inflammatory profiles in the pathogenesis of Sjogren syndrome by Jingyi Xu, Shucheng Si, Yijun Han, Lin Zeng, Jinxia Zhao

    Published 2025-01-01
    “…Abstract Background Sjogren syndrome (SS) is a chronic systemic autoimmune disease and its pathogenesis often involves the participation of numerous immune cells and inflammatory factors. …”
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    Identification of hub biomarkers and immune cell infiltrations participating in the pathogenesis of endometriosis by Kang Li, Jiaxu Wang, Xuyue Liu, Yifei Dang, Kaiting Wang, Manyu Li, Xiaoli Zhang, Yuan Liu

    Published 2025-01-01
    “…As is well known, immune cell infiltrations (ICIs) play important roles in the pathogenesis of EM. However, the pathogenesis and biomarkers of EM that can be used in clinical practice and their relationship with ICIs still need to be elucidated. …”
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    Article
  9. 169

    Facioscapulohumeral muscular dystrophy: a review of pathogenesis, clinical symptoms, and treatment by T. Mikalauskas, B. Burnytė

    Published 2023-10-01
    “…In recent years, significant progress has been made in understanding the pathogenesis, clinical features, and progression of the disease, but there is still no specific treatment due to the obstacles in the development of gene therapy. …”
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  10. 170

    The Role of TLR2, TLR4, and TLR9 in the Pathogenesis of Atherosclerosis by Mohsin H. K. Roshan, Amos Tambo, Nikolai P. Pace

    Published 2016-01-01
    “…Toll-like receptors (TLRs) are key players in the pathogenesis of inflammatory conditions including coronary arterial disease (CAD). …”
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  11. 171

    Metallothioneins in Inflammatory Bowel Diseases: Importance in Pathogenesis and Potential Therapy Target by Anna Socha-Banasiak, Patrycja Sputa-Grzegrzółka, Jędrzej Grzegrzółka, Krzysztof Pacześ, Piotr Dzięgiel, Beata Sordyl, Hanna Romanowicz, Elżbieta Czkwianianc

    Published 2021-01-01
    “…Immunological disorders, increased oxidative stress, and damage to the epithelial barrier play an important role in the pathogenesis of inflammatory bowel diseases (IBDs). In the treatment of patients with Crohn’s disease (CD) and ulcerative colitis (UC), it is increasingly common to use biological drugs that selectively affect individual components of the inflammatory cascade. …”
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  12. 172

    An updated review on abnormal epigenetic modifications in the pathogenesis of systemic lupus erythematosus by Xingyu Zhou, Shengnan Zhou, Yaping Li

    Published 2025-01-01
    “…Abnormal epigenetic regulation is strongly associated with the pathogenesis of SLE. Epigenetic mechanisms may be involved in the development of lupus through DNA methylation, histone modification, noncoding RNAs, and other modifications. …”
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  13. 173

    The Role of Serum Cytokines in the Pathogenesis of Hepatic Osteodystrophy in Male Cirrhotic Patients by Ali Riza Soylu, Cengiz Tuglu, Ender Arikan, Tarkan Yetisyigit, Hakan Kunduracılar, Ibrahim Hakki Koker, Gulbin Unsal, Ahmet Huseyin Tezel, Hasan Umit, Sakir Berkarda

    Published 2012-01-01
    “…According to the results of the study in this small population of 44 male cirrhotic patients, frequency of hepatic osteopenia is small and serum interleukins 1, 2, 6, 8, and tumor necrosis factor-alpha may not play a role in the pathogenesis of hepatic osteodystrophy. Further studies in which large number of patients involved are necessary in this field.…”
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    Exosomes in Human Immunodeficiency Virus Type I Pathogenesis: Threat or Opportunity? by Sin-Yeang Teow, Alif Che Nordin, Syed A. Ali, Alan Soo-Beng Khoo

    Published 2016-01-01
    “…This review summarizes the two distinctive roles of exosomes in regulating HIV pathogenesis. We also highlighted several additional factors that govern the exosomal functions. …”
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    Alarmins and their pivotal role in the pathogenesis of spontaneous abortion: insights for therapeutic intervention by Qiqi Zhang, Dandan Yang, Xingxing Han, Yu Ren, Yongqi Fan, Chao Zhang, Lei Sun, Tingting Ye, Qiushuang Wang, Youhao Ban, Yunxia Cao, Huijuan Zou, Zhiguo Zhang

    Published 2024-12-01
    “…Spontaneous abortion (SA) is a common pregnancy-related disease, and its pathogenesis has been puzzling clinicians, so it needs to be further studied. …”
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  20. 180

    STAT signaling in the pathogenesis and therapy of acute myeloid leukemia and myelodysplastic syndromes by Zoe King, Sudhamsh Reddy Desai, David A. Frank, Aditi Shastri

    Published 2025-03-01
    “…Recent research has underscored the critical role of aberrant STAT signaling pathways, particularly involving STAT3 and STAT5, in the pathogenesis of these disorders. Aberrant activation of STAT proteins has been implicated as a mediator of oncogenesis in several malignancies. …”
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