Interleukin-17: Potential Target for Chronic Wounds by Yasmin Hadian, Michelle D. Bagood, Sara E. Dahle, Apra Sood, R. Rivkah Isseroff

“…Since the interleukin-17 family has been implicated as a group of proinflammatory cytokines in immune-mediated diseases in the gut and connective tissue, as well as inflammatory skin conditions, we consider here if it may contribute to the pathogenesis of chronic wounds. In this review, we discuss the interleukin-17 family’s signaling pathways and role in tissue repair. …”
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Are Onconeural Antibodies a Clinical Phenomenology in Paraneoplastic Limbic Encephalitis? by Hongliang Zhang, Chunkui Zhou, Limin Wu, Fengming Ni, Jie Zhu, Tao Jin

“…This review provides an overview on the pathogenesis and diagnosis of PNS, with emphasis on the role of antibodies in limbic encephalitis.…”
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Influence of immune cells and inflammatory factors on Alzheimer’s disease axis: evidence from mediation Mendelian randomization study by Linzhu, Jianxin Zhang, Wenhui Fan, Chen Su, Zhi Jin

“…Conclusion This study provides valuable insights into the immunoinflammatory pathogenesis of AD and offers partial guidance for the development of relevant interventions, thereby contributing beneficial information for the prevention and treatment of related diseases.…”
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MiR-223 within neutrophil axis promotes Th17 expansion by PI3K-AKT pathway in systemic lupus erythematosus by Chengzhong Zhang, Yan Lu

“…Results We initially identified miR-223 as a pivotal factor in the pathogenesis of SLE in both MRL/lpr mice and SLE patients. …”
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Mechanisms of Cancer-Induced Bone Pain by Wang X, Li L, Wang Y

“…This study explores the pathogenesis of CIBP at the level of the spinal cord and describes recently proposed treatment methods for CIBP.Keywords: Cancer-induced bone pain, spinal cord, microglia, neuron, astrocyte…”
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Adult Vascular Wall Resident Multipotent Vascular Stem Cells, Matrix Metalloproteinases, and Arterial Aneurysms by Bruno Amato, Rita Compagna, Maurizio Amato, Raffaele Grande, Lucia Butrico, Alessio Rossi, Agostino Naso, Michele Ruggiero, Stefano de Franciscis, Raffaele Serra

“…Recent studies have implicated the role of matrix metalloproteinases in the pathogenesis of arterial aneurysms: in fact the increased synthesis of MMPs by arterial SMCs is thought to be a pivotal mechanism in aneurysm formation. …”
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Nonpharmacological Modulation of Chronic Inflammation in Parkinson’s Disease: Role of Diet Interventions by Stefania Kalampokini, Anouck Becker, Klaus Fassbender, Epameinondas Lyros, Marcus M. Unger

“…Recent evidence suggests that neuroinflammation in PD might originate in the intestine and the bidirectional communication between the central and enteric nervous system, the so-called “gut-brain axis,” has received growing attention due to its contribution to the pathogenesis of neurological disorders. Diet targets mediators of inflammation with various mechanisms and combined with dopaminergic treatment can exert various beneficial effects in PD. …”
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Treatment of Nonalcoholic Steatohepatitis in Adults: Present and Future by S. Gitto, G. Vitale, E. Villa, P. Andreone

“…Among the emerging treatments, telmisartan is particularly interesting as it seems to have an impact on insulin resistance, liver steatosis, inflammation, and fibrosis. However, the pathogenesis of steatohepatitis is highly complex and is determined by different parallel hits; indeed, the association of different drugs that act on various levels has been suggested. …”
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Cryptogenic Multifocal Ulcerous Stenosing Enteritis: A Review of the Literature by Darina Kohoutová, Jolana Bártová, Ilja Tachecí, Stanislav Rejchrt, Rudolf Repák, Marcela Kopáčová, Jan Bureš

“…The etiology is unknown and pathogenesis is not fully understood. Therapy with systemic glucocorticosteroids is the treatment of choice. …”
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The Emerging Roles of the Calcineurin-Nuclear Factor of Activated T-Lymphocytes Pathway in Nervous System Functions and Diseases by Maulilio John Kipanyula, Wahabu Hamisi Kimaro, Paul F. Seke Etet

“…Evidence from murine and cell line models has implicated calcineurin-nuclear factor of activated T-lymphocytes (NFAT) signaling pathway, a Ca2+/calmodulin-dependent major proinflammatory pathway, in the pathogenesis of these diseases. Neurotoxins such as amyloid-β, tau protein, and α-synuclein trigger abnormal calcineurin/NFAT signaling activities. …”
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Scoping Review of the Zika Virus Literature. by Lisa A Waddell, Judy D Greig

“…The articles mainly covered three topic categories: epidemiology of ZIKV (surveillance and outbreak investigations) 56.6% (132/233), pathogenesis of ZIKV (case symptoms/ outcomes and diagnosis) 38.2% (89/233) and ZIKV studies (molecular characterisation and in vitro evaluation of the virus) 18.5% (43/233). …”
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Anticardiolipin Autoantibodies as Useful Biomarkers for the Prediction of Mortality in Septic Patients by Amal Abouda, Z. Hajjej, A. Mansart, W. Kaabechi, D. Elhaj Mahmoud, O. Lamine, E. Ghazouani, M. Ferjani, I. Labbene

“…The detection of antiphospholipid antibodies (aPL) is of interest because of their importance in the pathogenesis of arterial or venous thrombosis. They could be a “second hit” of an inflammatory event such as infection. …”
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Pan-Cancer Analyses of the Tumor Microenvironment Reveal That Ubiquitin-Conjugating Enzyme E2C Might Be a Potential Immunotherapy Target by Guang-zhao Huang, Ze-qun Chen, Juan Wu, Ting-ru Shao, Chen Zou, Yi-long Ai, Xiao-zhi Lv

“…UBE2C was differentially expressed in many cancer types and related to the pathogenesis and TME of many cancers, which might be a potential diagnostic and therapeutic biomarker.…”
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The occurrence of wheat crown rot correlates with the microbial community and function in rhizosphere soil by Yajiao Wang, Jian Feng, Jianhai Gao, Sen Han, Qiusheng Li, Lingxiao Kong, Yuxing Wu

“…These findings contribute to understanding WCR pathogenesis and offer practical resources for its management.…”
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Anti-proliferative and photodynamic activities of Senna didymobotrya (Fresen.) leaf alkaloid-rich extracts against breast cancer cells by Kolawole A. Olofinsan, Heidi Abrahamse, Blassan P. George

“…Conclusion Although the in silico analysis suggests that the plant-identified alkaloid phytoconstituents inhibition of estrogen receptor-alpha, human epidermal growth factor receptor-2 and progesterone receptor proteins involved in breast cancer pathogenesis could explain a possible mechanism for the observed anticancer effect, more detailed in vitro molecular experiments are necessary to confirm these findings.…”
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Probing the Hepatic Progenitor Cell in Human Hepatocellular Carcinoma by Shu-Qin Jia, Jian-Jun Ren, Pei-De Dong, Xing-Kai Meng

“…By exposure of different injuries and different hepatocarcinogenic regimens, the mature hepatocytes can no longer effectively regenerate; stem cells are involved in the pathogenesis of hepatocellular carcinoma. Methods. Immunohistochemistry was performed on 107 paraffin-embedded hepatocellular carcinoma specimens with the marker of hepatocyte and hepatocellular carcinoma (HepPar1), biliary differentiation (CK7,CK19), haemopoietic stem cell (HSC) (c-kit/CD117, CD34, and Thy-1/CD90), HPC specific markers (OV-6), and Ki-67, p53 protein. …”
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A study of serum prolactin in dermatological diseases in a tertiary care hospital of Assam by Talukdar C, Boro B

“…Conclusions: Prolactin may play a role in the pathogenesis of psoriasis, alopecia areata, and vitiligo; and may serve as a biochemical marker of disease severity in patients with psoriasis and alopecia areata. …”
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lncRNA RUNDC3A-AS1 Regulates Proliferation and Apoptosis of Thyroid Cancer Cells via the miR-151b/SNRPB Axis by Yan Deng, Jie Wu, Xin Li

“…Many previous reports have confirmed that lncRNA is involved in the pathogenesis of THCA. However, the role and mechanism of lncRNA RUNDC3A-AS1 in THCA have not been studied. …”
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A Study of the Granulomatous Responses Induced by Different Strains of Schistosoma mansoni by Nádia Regina Borim Zuim, Silmara Marques Allegretti, Arício Xavier Linhares, Luiz Augusto Magalhães, Eliana Maria Zanotti-Magalhães

“…The increased pathogenesis of the Schistosoma mansoni BH strain compared with the SJ strain has been attributed to the number of granulomas formed in experimental infections, which increase the mortality in definitive hosts. …”
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A Combination of Serum Biomarkers in Elderly Patients with Sarcopenia: A Cross-Sectional Observational Study by Lin Ying, Qin Zhang, Yun-mei Yang, Jian-ying Zhou

“…Background. The pathogenesis of sarcopenia in the elderly has not yet been fully understood. …”
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