Pathophysiologic Mechanisms of Cardiovascular Disease in Obstructive Sleep Apnea Syndrome by Carlos Zamarrón, Luis Valdés Cuadrado, Rodolfo Álvarez-Sala

“…OSAS contributes to the pathogenesis of cardiovascular disease independently and by interaction with comorbidities. …”
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Autoantibody with Cross-Reactivity between Insulin and Ductal Cells May Cause Diabetic Mastopathy: A Case Study by Katsutoshi Miura, Chikako Teruya, Nasu Hatsuko, Hiroyuki Ogura

“…The condition usually affects women with a long history of diabetes mellitus (DM) and also those with autoimmune disorders. While the pathogenesis is unknown, a particular type of class II human leukocyte antigen has been associated with this disease. …”
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Hematological study of patients with recurrent aphthous stomatitis - Case control study by Shaheen Ali Ahmed, Ali Fakhree Alzubaidee

“… Background and Objectives: Recurrent aphthous stomatitis is common oral condition, characterized by multiple, recurrent, small, round, or ovoid ulcers with circumscribed, erythematous haloes, and yellow or grey floors. Its etiology and pathogenesis is not entirely clear linked to systemic diseases and among these, anemia, iron deficiency, folic- acid, and vitamin B12 deficiencies. …”
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PARP4 deficiency enhances sensitivity to ATM inhibitor by impairing DNA damage repair in melanoma by Yuehua Li, Yu Liu, Jingjing Ma, Yuqi Yang, Qiao Yue, Guannan Zhu, Weinan Guo, Tianwen Gao, Qiong Shi, Chunying Li

“…Overall, our study provides new and valuable insights into the function of PARP4 and melanoma pathogenesis and suggests that ATM inhibitor may be a promising therapeutic approach for treating melanoma with low PARP4 expression.…”
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The Role of Dendritic Cell Subsets in Recurrent Spontaneous Abortion and the Regulatory Effect of Baicalin on It by Nannan Lai, Xiaoxiao Fu, Guozhen Hei, Weiwei Song, Ran Wei, Xiaoxiao Zhu, Qiang Guo, Zhen Zhang, Chu Chu, Ke Xu, Xia Li

“…Our research further proved that DCs play an important role in the pathogenesis of RSA and baicalin might be used for treating RSA.…”
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Heme alters biofilm formation in Mycobacterium abscessus by Hadia Aftab, Jessica Samudio, Grace Wang, Lily Le, Rajesh K. Soni, Rebecca K. Donegan

“…We have found that extracellular heme can change the way Mabs cells grow and form biofilms, which may have implications for pathogenesis.…”
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Prevalence and Types of Coinfections in Sleeping Sickness Patients in Kenya (2000/2009) by J. M. Kagira, N. Maina, J. Njenga, S. M. Karanja, S. M. Karori, J. M. Ngotho

“…In conclusion, the study has shown that HAT patients have multiple co-infections which may influence the disease pathogenesis and complicate management of HAT.…”
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Prospects of Using Microbiota Correction Methods in the Treatment of Inflammatory Bowel Disease by A. I. Akinshina, D. V. Smirnova, A. V. Zagainova, V. V. Makarov, S. M. Yudin

“…In recent years, preference has been given to more accurate and faster molecular genetic methods allowing a more detailed study of the key mechanisms by which microbiota affects the intestine in Crohn’s disease (CD) and ulcerative colitis (UC), as well as of the effect of microbial metabolites on their pathogenesis. The article provides an overview of main microbiota metabolites and their role in regulating the intestinal barrier function. …”
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The role of CLDN11 in promotion of granulosa cell proliferation in polycystic ovary syndrome via activation of the PI3K-AKT signalling pathway by Min Wang, Tong Chen, Jiani Zheng, Caomeihui Shen, Guitian He, Jingshun Zhang, Boqi Zhang, Lianwen Zheng

“…The causes of PCOS are multifaceted, and its pathogenesis is not yet clear. This study established a rat model of PCOS and, in conjunction with clinical samples and database data, analysed the role of claudin 11 (CLDN11) in follicular granulosa cells (GCs) in regulating the proliferation of GCs. …”
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Establishment of Gill-Derived Primary Cell Cultures from Largemouth Bass (<i>Micropterus salmoides</i>) as an Alternative Platform for Studying Host–Virus Interactions by Ziwen Wang, Li Nie, Chenjie Fei, Jiong Chen

“…These findings highlight the utility of the largemouth bass gill-derived primary cell culture as an alternative in vitro system for investigating MSRV pathogenesis and host immune responses, which serves as a stepping stone for improved antiviral strategies in largemouth bass aquaculture.…”
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A H2S Donor GYY4137 Exacerbates Cisplatin-Induced Nephrotoxicity in Mice by Mi Liu, Zhanjun Jia, Ying Sun, Aihua Zhang, Tianxin Yang

“…Accumulating evidence demonstrated that hydrogen sulfide (H2S) is highly involved in inflammation, oxidative stress, and apoptosis and contributes to the pathogenesis of kidney diseases. However, the role of H2S in cisplatin nephrotoxicity is still debatable. …”
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Evaluating Neural Network Performance in Predicting Disease Status and Tissue Source of JC Polyomavirus from Patient Isolates Based on the Hypervariable Region of the Viral Genome by Aiden M. C. Pike, Saeed Amal, Melissa S. Maginnis, Michael P. Wilczek

“…These models can improve viral sequence identification and provide insights into viral mutations and pathogenesis.…”
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Respiratory Syncytial Virus Nonstructural Protein 1 Promotes 5-Lipoxygenase via miR-19a-3p by Mei Zheng, Panpan Fan, Pu Yang, Junwen Zheng, Dongchi Zhao

“…These results suggested that the RSV NS1 might play an important role in the pathogenesis of RSV by activating the 5-LO and subsequent inflammatory cytokines through miR-19a-3p.…”
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The association of serum phospholipids levels with chronic kidney disease: A systematic review of observational studies by Zahra Shahveghar Asl, Faezeh Ghalichi, Mohadeseh Badpeyma, Zohreh Ghoreishi

“…Introduction: Chronic kidney disease (CKD) affects the levels of various metabolites, which may be associated with pathogenesis of chronic diseases. This study aimed to indicate the association between CKD and changes in the levels of phospholipids. …”
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Metabolic and Genetic Determinants of Lipid Metabolism Disruption in Non-Alcoholic Fatty Liver Disease by O. Yu. Kytikova, T. P. Novgorodtseva, Yu. K. Denisenko, D. A. Kovalevsky

“…Further research into the NAFLD genetic mechanisms regulating the metabolism of fatty acids appears to be promising for a deeper understanding of the pathogenesis of this multifactorial disease.…”
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Digging deeper into necrotizing enterocolitis: bridging clinical, microbial, and molecular perspectives by Deshuang Zhang, Dongke Xie, Yi Qu, Dezhi Mu, Shaopu Wang

“…This review consolidates evidence from various biomedical disciplines to elucidate the complex pathogenesis of NEC, integrating insights from clinical, microbial, and molecular perspectives. …”
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Why Does Pnemococcus Kill? by Yves Bergeron, Michel G Bergeron

“…This paper reviews the major bacterial virulence factors and pathogenesis steps that characterize fatal pneumococcal pneumonia, with a focus on the inflammation that was observed from the initial infection to death in an experimental murine pneumonia model. …”
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Higher risk of carotid plaque among lean individuals with non-alcoholic fatty liver disease: A retrospective study. by Jiangfeng Xue, Lun Zhao, Liang Shao, Huiwang Zhang, Yewei Feng, Ping Shuai

“…<h4>Background</h4>Lean individual with non-alcoholic fatty liver disease (L-NAFLD) is a prominent area of research, yet its pathogenesis and association with other diseases such as atherosclerotic cardiovascular disease remain uncertain.…”
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Chikungunya: From Hypothesis to Evidence of Increased Severe Disease and Fatalities by Carlos Brito, Melissa Barreto Falcão, Maria de Fatima Pessoa Militão de Albuquerque, Thiago Cerqueira-Silva, Maria Glória Teixeira, Rafael Freitas de Oliveira Franca

“…Studies were identified through PubMed using the search terms “chikungunya”, “death”, “severe”, “pathogenesis”, and “pathophysiology”.…”
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Innovative nanoparticle-based approaches for modulating neutrophil extracellular traps in diseases: from mechanisms to therapeutics by Haisong Li, Can Li, Cong Fu, Yizhuo Wang, Tingting Liang, Haitao Wu, Chenxi Wu, Chang Wang, Tianmeng Sun, Shuhan Liu

“…Abstract Neutrophil extracellular traps (NETs) participate in both host defense and the pathogenesis of various diseases, such as infections, thrombosis, and tumors. …”
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