Coronary Microvascular Dysfunction: Insights on Prognosis and Future Perspectives by Filippo Luca Gurgoglione, Giorgio Benatti, Andrea Denegri, Davide Donelli, Marco Covani, Mattia De Gregorio, Gabriella Dallaglio, Rebecca Navacchi, Giampaolo Niccoli

“…This review aims to elucidate briefly the pathogenesis and diagnostic modalities of CMD and to shed light on contemporary evidence on the prognostic impact of CMD. …”
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The relationship between Helicobacter pylori and pityriasis versicolor by May H. El Samahy, Raafat Z. Abdelrahman, Hossam O. Ibrahim, Azza E. Mostafa

“…Background Although the immune dysregulation caused by Helicobacter pylori has been linked to the pathogenesis of many dermatological diseases, the link between H. pylori infection and pityriasis versicolor (PVC) has not been largely verified. …”
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Type I Diabetes-Associated Tolerogenic Properties of Interleukin-2 by Aziz Alami Chentoufi, Simon Gaudreau, Alex Nguyen, Mahmoud Sabha, Abdelaziz Amrani, Geyhad ElGhazali

“…We further discuss a potential link between the immunomodulatory role of interleukin-2 and the pathogenesis of type 1 diabetes.…”
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Effect of an inhaled glucocorticoid on reactive oxygen species production by bronchoalveolar lavage cells from smoking COPD patients by Gert T. Verhoeven, Annemarie J.M. Wijkhuijs, Herbert Hooijkaas, Henk C. Hoogsteden, Wim Sluiter

“…Oxidative stress in the lung is important in the pathogenesis of COPD. Published data indicate that glucocorticoids inhibit blood cells in their capacity to produce reactive oxygen species (ROS). …”
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Euglycemic diabetic ketoacidosis associated metabolic encephalopathy caused by dapagliflozin: a rare case report by Lulu Chu, Zhenhua Xi, Runzhi Ma, Weiliang Shi, Guoshen Yu

“…Conclusions Metabolic encephalopathy is a rare but life-threatening complication of EuDKA caused by SGLT-2 inhibitors, the imaging features are similar to those of other metabolic encephalopathy such as poisoning and hypoxia. The precise pathogenesis of encephalopathy in EuDKA remains poorly understood, potentially resulting from the toxic consequences of electrolyte disturbances, ketosis, and acidosis.Testing the level of ketones is essential for unconscious patients who are taking SGLT-2 inhibitors.…”
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Immunopathogenesis of inflammatory bowel diseases by Ye. A. Konovich, I. L. Khalif, M. V. Shapina

“…Investigations of experimental enterocolites and human IBD confirm immunologic hypothesis of pathogenesis: relation of their development to defects of innate and adaptive immune system.…”
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Decoding the Methylation Patterns of ABC Transporters in Colorectal Cancer by Nurul Nabilah Norhisan, Rashidah Baharudin, Nurul Qistina Rus Bakarurraini, Nur Alyaa Afifah Md Shahri, Francis Yew Fu Tieng, Imilia Ismail, Muhammad-Redha Abdullah-Zawawi, Learn-Han Lee, Nurul Syakima Ab Mutalib

“…Further research is needed to validate these results and investigate the functional implications of ABC gene methylation in CRC pathogenesis and treatment response. …”
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Metabolic plasticity in pancreatic cancer: The mitochondrial connection by Noemi Ghiglione, Damiano Abbo, Anastasia Bushunova, Andrea Costamagna, Paolo Ettore Porporato, Miriam Martini

“…We discuss the significance of mitophagy dysregulation in PDAC pathogenesis, emphasizing its influence on treatment responses and prognosis. …”
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Etiopathogenesis and surgical treatment of epithelial pilonidal sinus by A. Yu. Titov, I. V. Kostarev, A. K. Batischev

“…Up to now there is no common judgement on etiology and pathogenesis of epithelial pilonidal sinus. All theories may be divided to two basic classes: congenital and acquired EPS. …”
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BIOCHEMICAL ANALYSIS OF SALIVARY MALONDIALDEHYDE LEVELS IN 14-15-YEAR-OLD ADOLESCENTS WITH ORAL PATHOLOGY by Alexandra Mihaela Stoica, Oana Elena Stoica, Alexandru Vlasa, Cristina Ioana Bica, Liana Bereșescu, Zsuzsanna Bardocz-Veres, Monica Dana Monea

“…Conclusions: The levels of salivary MDA were higher in the study groups with GT and AU, with statistically significant differences (p<0.05) compared to healthy subjects, which questions weather oxidative stress might be linked to geographic tongue pathogenesis or aphthous ulcers.…”
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Potential of nutraceutical products for irritable bowel syndrome remission maintenance by A. I. Ulyanin, Ye. A. Poluektova, Ch. S. Pavlov, V. T. Ivashkin

“…To summarize the modern data on pathogenesis of symptoms irritable bowel syndrome (IBS) symptoms, to present nutraceutical product «Standart zdorovya: GASTRO» as an agent for IBS remission maintenance. …”
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Preconditioning Serum Levels of Endothelial Cell-Derived Molecules and the Risk of Posttransplant Complications in Patients Treated with Allogeneic Stem Cell Transplantation by Roald Lindås, Tor Henrik Andersson Tvedt, Kimberley Joanne Hatfield, Håkon Reikvam, Øystein Bruserud

“…Endothelial cells are involved in the pathogenesis of acute graft-versus-host disease (GVHD) after allogeneic stem cell transplantation. …”
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Periodontal Disease: A Covert Source of Inflammation in Chronic Kidney Disease Patients by Gener Ismail, Horia Traian Dumitriu, Anca Silvia Dumitriu, Fidan Bahtiar Ismail

“…Increasing evidence suggests that both in general population and in dialysis patients, systemic inflammation plays a dominant role in the pathogenesis of atherosclerotic complications. In general population, also, evidence shows that moderate to severe periodontitis can contribute to inflammatory burden by increasing serum CRP levels and may increase the prevalence of atherosclerotic events. …”
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Cryptosporidiosis in a Zoonotic Gastrointestinal Disorder Perspective by Thivya Balendran, Devika Iddawela, Sajanee Lenadora

“…We analyzed reports on Cryptosporidium in immunocompromised patients with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), cancer, primary immunodeficiency, and organ transplant recipients. 134 Articles describing epidemiology, related risk factors, clinical presentation, diagnosis, and possible treatments in the light of pathogenesis, pathophysiology, and virulence factors of Cryptosporidium and immunology of the host are summarized in this study. …”
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BA inhibits LPS-stimulated inflammatory response and apoptosis in human middle ear epithelial cells by regulating the Nf-Kb/Iκbα axis by He Qian, Cai Yanzhi, Kong Meihua

“…Otitis media (OM) is a prevalent childhood ear disease characterized by inflammation of the middle ear cavity, which can lead to ear pain, fever, and hearing loss. The pathogenesis of OM is multifaceted, encompassing a variety of factors including bacterial or viral infections, host immune responses, and the function of middle ear epithelial cells. …”
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Opicapone, a Novel Catechol-O-methyl Transferase Inhibitor, for Treatment of Parkinson's Disease "Off" Episodes by Amnon A. Berger, Ariel Winnick, Jonathan Izygon, Binil M. Jacob, Jessica S. Kaye, Rachel J. Kaye, Elisa E. Neuchat, Adam M. Kaye, Edward S. Alpaugh, Elyse M. Cornett, Andrew H. Han, Alan D. Kaye

“…It causes significant morbidity and disability through a plethora of symptoms, including movement disorders, sleep disturbances, and cognitive and psychiatric symptoms. The traditional pathogenesis theory of PD involves the loss of dopaminergic neurons in the substantia nigra (SN). …”
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Spatiotemporal Pattern of Neuroinflammation After Impact-Acceleration Closed Head Injury in the Rat by Servan Rooker, Sebastian Jander, Jos Van Reempts, Guido Stoll, Philippe G. Jorens, Marcel Borgers, Jan Verlooy

“…Inflammatory processes have been implicated in the pathogenesis of traumatic brain damage. We analyzed the spatiotemporal expression pattern of the proinflammatory key molecules: interleukin-1β, interleukin-6, tumor necrosis factor-α, and inducible nitric oxide synthase in a rat closed head injury (CHI) paradigm. 51 rats were used for RT-PCR analysis after CHI, and 18 for immunocytochemistry. …”
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Gastrointestinal Dysfunctions Are Associated with IL-10 Variants in Parkinson’s Disease by Li Shu, Dongxiao Liang, Hongxu Pan, Qian Xu, Xinxiang Yan, Beisha Tang, Qiying Sun

“…Inflammation has been demonstrated to be involved in Parkinson’s disease (PD) pathogenesis. There were evidences that the disturbance of the protective function of IL-10 gene contributed to PD. …”
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Reframing the Management of Irritable Bowel Syndrome: Investigating the Efficacy of a Modified Low Fodmap Diet Approach on Symptom Response by Tara Howley, Lorraine Cooney, Suzanne L Doyle

“…Background/ Objectives: Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction with a multi-faceted pathogenesis. A diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs), known as a low FODMAP diet (LFD), is an effective management option for many, however, it is complex, costly, and restrictive. …”
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A bibliometric analysis of research on dementia comorbid with depression from 2005 to 2024 by Xia Li, Wei Su, Lili Cai

“…Additionally, there is a growing interest in the physiological and psychological interplays such as oxidative stress and its implications.ConclusionThis study underscores pathogenesis, comorbid conditions, and non-drug interventions as primary research focal points, suggesting these areas as potential pathways for therapeutic innovation. …”
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