Serum Magnesium and Vitamin D Levels as Indicators of Asthma Severity by Mohammed Nadeem Shaikh, Brahma Reddy Malapati, Ruchi Gokani, Bhavita Patel, Mitul Chatriwala

“…Serum magnesium levels affect the concentration of circulating vitamin D in blood and subsequently it affects the immunity; thus it plays significant role in the pathogenesis of asthma. Asthma, in adults, is less studied and hypomagnesemia along with vitamin D deficiency and insufficiency is common in asthmatic individuals, which causes frequent asthma attacks, respiratory infections, severe exacerbations, and poor response to bronchodilators. …”
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A Case of Successful Treatment with Unilateral Oophorectomy in a Patient with Resistant Polycystic Ovary Syndrome by S. Pathmanathan, I. Ranathunga, N. P. Somasundaram

“…Typical features consist of oligo/anovulation, polycystic ovaries, and features of hyperandrogenism. Pathogenesis is multifactorial, and positive family history may have a predisposition for disease development. …”
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Sarcoid of the Upper Humerus Found Incidentally on MR Images Obtained for Work-Up of Rotator Cuff Tear Where Compromised Tissue Quality Was a Concern for Surgical Success by Tanner R. Henrie, John G. Skedros

“…Sarcoidosis is an idiopathic systemic inflammatory disorder characterized histologically by noncaseating granulomas. The pathogenesis likely includes genetic, immunologic, and environmental factors. …”
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RatDNA: DATABASE ON MICROARRAY STUDIES OF RATS BEARING GENES ASSOCIATED WITH AGE-RELATED DISEASES by O. S. Kozhevnikova, M. K. Martyschenko, M. A. Genaev, E. E. Korbolina, N. A. Muraleva, N. G. Kolosova, Y. L. Orlov

“…They underlie the pathogenesis of this disease, but not always lead to its development. …”
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Recapitulation of Candidate Systemic Lupus Erythematosus-Associated Variants in Koreans by Ki-Sung Kwon, Hye-Young Cho, Yeun-Jun Chung

“…Although the etiology of SLE remains unclear, it is widely accepted that genetic factors could be involved in its pathogenesis. A number of genome-wide association studies (GWASs) have identified novel single-nucleotide polymorphisms (SNPs) associated with the risk of SLE in diverse populations. …”
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Spontaneous splenic rupture associated with Q fever and portal hypertension: A case report by Cecil Mustafiz, Cecil Mustafiz, Deloshaan Subhaharan, Deloshaan Subhaharan, Daniel Chorley, Tariq Masood

“…This case underlines the critical need to consider rare etiologies, offers valuable insights into the pathogenesis of SSR, and emphasizes the importance of early recognition and multidisciplinary management. …”
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Association of CYP11A1 Polymorphisms with Recurrent Pregnancy Loss in the Female Population of Punjab by Amanjot Kaur Rayat, Pallvi Thapar, Mandeep Kaur, Sukhjashanpreet Singh, Anupam Kaur

“…Conclusion: CYP11A1 variants (rs11632698 and rs4077582) may be useful markers in determining the genetic susceptibility to the pathogenesis of RPL. Keywords: CYP11A1, recurrent miscarriage, recurrent pregnancy loss, rs11632698, rs4077582, spontaneous abortion.…”
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Glomerular parietal epithelial expression of CD44 in minimal change nephrotic syndrome and primary focal segmental glomerulosclerosis: A clinico-pathological study by Nithin E Paul, Suchitha Satish, Kiran Krishnamurthy Kelur, Manjunath Sanjeev Shetty

“…CD44 is expressed by activated parietal epithelial cells, plays a role in matrix deposition and thus in the pathogenesis of FSGS. Aims: To assess the expression of CD44 in MCNS and FSGS and to evaluate its association with the known clinical and histopathological prognostic factors. …”
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Propranolol: A Promising Therapeutic Avenue for Classic Kaposi Sarcoma by Rasha Mahmoud Genedy, Marwa Owais, Naglaa Mohamed El Sayed

“…Human herpes virus 8 (HHV8) plays a major role in the pathogenesis of KS. Classic Kaposi sarcoma is commonly seen among elderly of Mediterranean origin. …”
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Sclerema Neonatorum in a Term Infant: A Case Report and Literature Review by Gloria Nakalema, Walufu Ivan Egesa, Patrick Kumbowi Kumbakulu, Martin Nduwimana, Amnia Diaz Anaya, Mirembe Stephen Kizito, Daniel Kavuma

“…Sclerema neonatorum (SN) is a rare form of panniculitides with an obscure incidence, aetiology, and pathogenesis. This condition is peculiar to preterm neonates, especially those with comorbidities such as sepsis, congenital anomalies, congenital heart disease, and gastrointestinal and respiratory diseases. …”
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MicroRNAs in atrial fibrillation – have we discovered the Holy Grail or opened a Pandora’s box? by Alkora Ioana Balan, Alina Scridon

“…In recent years, special attention has been paid to microRNAs (miRNAs) as potential regulators of AF pathogenesis. Through post-transcriptional regulation of genes, miRNAs have been shown to play crucial roles in AF-related structural and electrical atrial remodeling. …”
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Microarray Profiling of Lymphocytes in Internal Diseases With an Altered Immune Response: Potential and Methodology by Anatoliy Gladkevich, S. Adriaan Nelemans, Henk F. Kauffman, Jakob Korf

“…Lymphocytes express more than 75% of the human genome, and, being an important part of the immune system, they play a central role in the pathogenesis of asthma, RA, and SLE. Here we review alterations of gene expression in lymphocytes and methodological aspects of the microarray technique in these diseases. …”
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Altered Phenotype of Circulating Dendritic Cells and Regulatory T Cells from Patients with Acute Myocarditis by Paola del Carmen Guerra-de-Blas, Daniela Cruz-González, Elena B. Martínez-Shio, Roberto González-Amaro, Héctor González-Pacheco, Esther Layseca-Espinosa, Carlos D. Escobedo-Uribe, Adriana E. Monsiváis-Urenda

“…This proinflammatory status may contribute to the pathogenesis and immune deregulation in acute myocarditis.…”
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Exploring Cervical Adenocarcinoma: Epidemiological Insights, Diagnostic and Therapeutic Challenges, and Pathogenetic Mechanisms by Shuhui Li, Congrong Liu, Liang Weng

“…There is limited understanding of the similarities and differences in the pathogenesis mechanisms between CA and SCC, such as tumor heterogeneity and the tumor immune microenvironment (TME). …”
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Effect of plasma free fatty acids on lung function in male COPD patients by Rostam Yazdani, Hossein Fallah, Shirin Yazdani, Beydolah Shahouzehi, Behnaz Danesh

“…Abstract Inflammation and oxidative stress play a pivotal role in COPD pathogenesis. Free fatty acids (FFA) as signaling molecules through a series of G-proteins coupled receptors, play an important role in regulation of the immune system and oxidative stress. …”
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The role of myocardial energy metabolism perturbations in diabetic cardiomyopathy: from the perspective of novel protein post-translational modifications by Dongze Li, Li Zhang, Qiming Gong, Huilan Deng, Changfang Luo, Tingting Zhou, Wei Huang, Yong Xu

“…This review examines the epigenetic pathogenesis of DbCM, primarily focusing on myocardial energy metabolism perturbations and novel PTMs associated with them. …”
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Cytokines in Pericardial Effusion of Patients with Inflammatory Pericardial Disease by Konstantinos Karatolios, Rainer Moosdorf, Bernhard Maisch, Sabine Pankuweit

“…It is thus possible that VEGF and bFGF participate in the pathogenesis of inflammatory pericardial disease.…”
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Severe Respiratory Distress in a Child with Pulmonary Idiopathic Hemosiderosis Initially Presenting with Iron-Deficiency Anemia by A. Potalivo, L. Finessi, F. Facondini, A. Lupo, C. Andreoni, G. Giuliani, C. Cavicchi

“…It is commonly characterized by the triad of recurrent hemoptysis, diffuse parenchymal infiltrates, and iron-deficiency anemia. Pathogenesis is unclear and diagnosis may be difficult along with a variable clinical course. …”
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The Impact of Autophagy on Cell Death Modalities by Stefan W. Ryter, Kenji Mizumura, Augustine M. K. Choi

“…., apoptosis), inflammation, and adaptive immune mechanisms and thereby influence disease pathogenesis. Selective pathways can target distinct cargoes (e.g., mitochondria and proteins) for autophagic degradation. …”
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The Correlation between Gut Microbiota and Serum Metabolomic in Elderly Patients with Chronic Heart Failure by Zhenhua Wang, Zhaoling Cai, Markus W. Ferrari, Yilong Liu, Chengyi Li, Tianzhang Zhang, Guorong Lyu

“…The mechanism and pathogenesis of myocardial remodeling remain unknown. …”
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