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1421
Severe Lactic Acidosis in a Patient with B-Cell Lymphoma: A Case Report and Review of the Literature
Published 2009-01-01“…There have been 29 cases of lymphoma induced lactic acidosis reported thus far; however all reported cases have abnormal vital signs or concomitant medical conditions that may lead to lactic acidosis. The pathogenesis of malignancy-induced lactic acidosis is not well understood; however associated factors include increased glycolysis, increased lactate production by cancer cells, and decreased hepatic clearance of lactate. …”
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1422
Thyrotoxic Periodic Paralysis: Case Reports and an Up-to-Date Review of the Literature
Published 2011-01-01“…Recent discovery of a novel mutation in the KCNJ18 gene which codes for an inwardly rectifying potassium channel and is controlled by thyroid hormones may provide greater insight into the pathogenesis of TPP.…”
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1423
Determination of lipid peroxidation biomarkers in vero cell line inoculated with bovine ephemeral fever virus
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1424
New T-lymphocyte subpopulations and their characteristics: Challenges to the classical division of lymphocyte function
Published 2024-11-01“…This article reviews these discoveries and their implications for understanding immune regulation and disease pathogenesis. Innovative techniques have enabled the identification of previously unrecognized T-lymphocyte subsets, disrupting the classical classification system. …”
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1425
Theoretical Construction and Clinical Application of "Flaccidity Caused by Deficiency and Congestion" of Osteoporosis
Published 2024-04-01“…Based on the basic theories such as "kidney governing bone" and "kidney deficiency", professor YAO Xinmiao of The Third Affiliated Hospital of Zhejiang Chinese Medical University creatively put forward the pathogenic theory of "flaccidity caused by deficiency and congestion" of OP, which holds that the pathogenesis of OP is the combination of deficiency and blood stasis, mixed with impotence. …”
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1426
Penile Livedoid Vasculopathy: First Reported Case
Published 2023-01-01“…Livedoid vasculopathy is a thromboocclusive cutaneous vasculopathy manifested by livedoid changes, atrophie blanche, and ulceration. The pathogenesis is speculated to involve increasing coagulation or impaired thrombolysis leading to the occlusion of dermal blood vessels with fibrin thrombi. …”
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1427
The Role of p38 MAPK in the Aetiopathogenesis of Psoriasis and Psoriatic Arthritis
Published 2013-01-01“…This review discusses the current data suggesting a crucial role for p38 MAPK in the pathogenesis of these disorders.…”
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1428
Oxidative stress in viral hepatitis
Published 2024-04-01“…Accumulating evidence suggests that oxidative stress (OS) plays a pivotal role in the pathogenesis and progression of viral hepatitis. OS occurs due to a disproportion between reactive oxygen species (ROS) generation and antioxidant protection, resulting in damage to cells and tissues. …”
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1429
Melatonin and its therapeutic prospects in gastroenterology
Published 2018-08-01“…The melatonin role in pathogenesis and prognosis of digestive diseases is covered. …”
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1430
Dietary content and eating behavior in ulcerative colitis: a narrative review and future perspective
Published 2025-01-01“…Current research into UC pathogenesis focuses on the complex interplay of genetic and environmental factors with the immune system and gut microbiome, leading to disruption of the intestinal barrier. …”
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1431
Innate Immune Response in Kidney Ischemia/Reperfusion Injury: Potential Target for Therapy
Published 2017-01-01“…Alloantigen-independent inflammation is an important process, participating in pathogenesis of injurious response, caused by ischemia and reperfusion. …”
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1432
The lactate metabolism and protein lactylation in epilepsy
Published 2025-01-01“…This study also examines the potential for histone deacetylase inhibitors to alleviate seizures by modifying lactylation levels, thereby offering fresh perspectives for future research into the pathogenesis and clinical treatment of epilepsy.…”
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1433
The link between optic neuritis and multiple sclerosis. Literature review
Published 2021-03-01“…Some aspects of epidemiology, etiology, pathogenesis, clinical signs, possibilities of diagnosis and treatment of optic neuritis together with the evaluation of the risk of multiple sclerosis development are discussed in this article. …”
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1434
Capsule Endoscopy for Portal Hypertensive Enteropathy
Published 2016-01-01“…Portal hypertensive enteropathy (PHE) is a mucosal abnormality of the small bowel that is observed in patients with portal hypertension (PH) and can lead to gastrointestinal bleeding and anemia. The pathogenesis is still not completely understood. The introduction of new endoscopic methods, including capsule endoscopy (CE) or balloon-assisted enteroscopy, has increased the detection of these abnormalities. …”
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1435
ABO Blood Groups and Cardiovascular Diseases
Published 2012-01-01“…The role of blood group antigens in the pathogenesis of various cardiovascular disorders remains a fascinating subject with potential to lead to novel therapeutics and prognostics and to reduce the global burden of cardiovascular diseases.…”
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1436
Asymmetric Dimethyl Arginine as a Biomarker of Atherosclerosis in Rheumatoid Arthritis
Published 2018-01-01“…Asymmetric dimethylarginine is gaining attention for its implication in the pathogenesis of endothelial dysfunction and as biomarkers of subclinical atherosclerosis. …”
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1437
Leukocyte migration in experimental inflammatory bowel disease
Published 1997-01-01“…The influx of neutrophils, monocytes and lymphocytes into inflamed tissue is important in the pathogenesis of chronic inflammatory bowel disease. The importance of each of these groups of adhesion molecules in chronic inflammatory bowel disease, either in human disease or in animal models, will be discussed below. …”
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1438
The Role of In Vivo Confocal Microscopy in Ocular Allergies
Published 2024-12-01“…IVCM can reveal subclinical abnormalities in the corneal and conjunctival epithelium such as inflammatory cell infiltrates and tissue damage, which can provide insight into the pathogenesis of AKC. In AKC, IVCM reveals changes around the conjunctival papillae, inflammatory cells around punctate defects in the corneal epithelium, changes in subbasal nerve morphology, and deteriorations in the goblet cells in the meibomian gland are observed. …”
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1439
A pan-orthohantavirus human lung xenograft mouse model and its utility for preclinical studies.
Published 2025-01-01“…This pan-orthohantavirus model will facilitate progress in the fundamental understanding of pathogenesis and virus-host interactions for orthohantaviruses. …”
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1440
Advancements in Research on Non-AR- Signaling Pathways and Targeted Therapies for Castration-Resistant Prostate Cancer
Published 2025-01-01“…While the androgen receptor (AR) signaling pathway is widely recognized as central to CRPC pathogenesis, emerging research highlights the critical involvement of the non-AR signaling pathway in the disease. …”
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