Effects of Various Flavonoids on the α-Synuclein Fibrillation Process by Xiaoyun Meng, Larissa A. Munishkina, Anthony L. Fink, Vladimir N. Uversky

“…α-Synuclein aggregation and fibrillation are closely associated with the formation of Lewy bodies in neurons and are implicated in the causative pathogenesis of Parkinson's disease and other synucleinopathies. …”
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Role of ferroptosis in atrial fibrillation: a review by Shaowei Fan, Yuanhui Hu, Jingjing Shi

“…This article provides a concise overview of the potential mechanisms by which ferroptosis may contribute to the pathogenesis of atrial fibrillation.…”
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Unraveling the AMPK-SIRT1-FOXO Pathway: The In-Depth Analysis and Breakthrough Prospects of Oxidative Stress-Induced Diseases by Guangqi Guan, Yaoxing Chen, Yulan Dong

“…This review provides a comprehensive analysis of the biological roles, regulatory mechanisms, and functions of the AMPK-SIRT1-FOXO pathway in diseases influenced by OS, offering new insights and methods for understanding OS pathogenesis and its therapeutic approaches.…”
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Hypertension in Chronic Kidney Disease: Navigating the Evidence by F. M. Tedla, A. Brar, R. Browne, C. Brown

“…In addition, chronic kidney disease encompasses a large group of clinical disorders with heterogeneous natural history and pathogenesis. In this paper, we review current evidence supporting treatment of hypertension in various forms of chronic kidney disease and highlight some of the gaps in the extant literature.…”
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White Matter Lesions and Cognitive Impairment as Silent Cerebral Disease in Hypertension by Cristina Sierra, Antonio Coca

“…Although the pathogenesis and clinical significance of cerebral white matter lesions remain controversial, it is well established that age and hypertension are the most important factors related to the presence of these lesions. …”
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Advances in Research Related to MicroRNA for Diabetic Retinopathy by Yahan Luo, Chunxia Li

“…The aim of this review is to systematically summarize the signaling pathways and molecular mechanisms of miRNAs involved in the occurrence and development of DR, mainly from the pathogenesis of oxidative stress, inflammation, and neovascularization. …”
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Glutamate Receptors in Neuroinflammatory Demyelinating Disease

“…The review considers the importance of the glutamate receptors in EAE and MS pathogenesis. The use of receptor antagonists to control EAE is also discussed together with the possibility of therapeutic application in demyelinating disease.…”
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Generalized Anxiety Disorder and Hypoglycemia Symptoms Improved with Diet Modification by Monique Aucoin, Sukriti Bhardwaj

“…This case strengthens the hypothesis that dietary glycemic index may play a role in the pathogenesis or progression of mental illnesses such as generalized anxiety disorder and subsequently that dietary modification as a therapeutic intervention in the treatment of mental illness warrants further study.…”
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Sympathetic Renal Innervation and Resistant Hypertension by Vito M. Campese, Elaine Ku, Jeanie Park

“…Several factors have been implicated in the pathogenesis of hypertension associated with renal disease and/or renal failure. …”
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Acute Eosinophilic Ascites in a Middle-Aged Man by Fadi Bleibel, Keith Fragoza, Garrey T. Faller

“…Eosinophilic gastroenteritis is a rare condition characterized by recurrent eosinophilic infiltration of portions of the GI tract and presenting with nonspecific GI symptoms in association with peripheral eosinophilia. Its etiology and pathogenesis remain unclear and its symptoms overlap with many GI and systemic diseases. …”
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Linking Neuroinflammation and Neurodegeneration in Parkinson’s Disease by Géraldine Gelders, Veerle Baekelandt, Anke Van der Perren

“…Recently, it has been postulated that neuroinflammatory processes might play a crucial role in the pathogenesis of PD. Numerous postmortem, brain imaging, epidemiological, and animal studies have documented the involvement of the innate and adaptive immunity in neurodegeneration. …”
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AAV-based vectors for human diseases modeling in laboratory animals by Timur I. Aliev, Dmitry V. Yudkin

“…The development of therapeutic drugs and vaccines requires the availability of appropriate model animals that replicate the pathogenesis of human diseases. Both native and transgenic animals can be utilized as models. …”
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Diverse Spectrum of Presentation of Coronary Slow Flow Phenomenon: A Concise Review of the Literature by Muhammad A. Chaudhry, Marcus Smith, Elias B. Hanna, Ralph Lazzara

“…A concise review of the literature is also provided emphasizing the epidemiology, pathogenesis, diagnostic parameters, treatment modalities, and clinical significance of this phenomenon.…”
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Fluorescently Labeled Adenovirus with pIX-EGFP for Vector Detection by Long P. Le, Maaike Everts, Igor P. Dmitriev, Julia G. Davydova, Masato Yamamoto, David T. Curiel

“…Adenoviruses are extensively studied in terms of their use as gene therapy vectors and pathogenesis. These vectors have been targeted on both transcriptional and transductional levels to achieve cell-specific gene delivery. …”
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Exosomes in Oral Diseases: Mechanisms and Therapeutic Applications by Miao Q, Li S, Lyu W, Zhang J, Han Y

“…Qiandai Miao, Shaoqing Li, Weijia Lyu, Jianxia Zhang, Yan Han Department of Stomatology, China Academy of Chinese Medical Sciences, Xiyuan Hospital, Beijing, 100091, People’s Republic of ChinaCorrespondence: Yan Han, Email hy1352111@163.comAbstract: Exosomes, small extracellular vesicles secreted by various cells, play crucial roles in the pathogenesis and treatment of oral diseases. Recent studies have highlighted their involvement in orthodontics, periodontitis, oral squamous cell carcinoma (OSCC), and hand, foot, and mouth disease (HFMD). …”
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Advances in small extracellular vesicles: roles in the tumor microenvironment and epithelial ovarian cancer diagnosis and treatment by Liang Peng, Yi Lai, Baodi Cao

“…These vesicles, released by cells into the extracellular space, are pivotal in the pathogenesis of EOC. In addition, sEVs show significant promise as biomarkers and therapeutic agents for the treatment and management of this malignancy. …”
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Refined methodology for quantifying Pseudomonas aeruginosa virulence using Galleria mellonella by Christopher M. R. Axline, Travis J. Kochan, Sophie Nozick, Timothy Ward, Tania Afzal, Issay Niki, Sumitra D. Mitra, Ethan VanGosen, Julia Nelson, Aliki Valdes, David Hynes, William Cheng, Joanne Lee, Prarthana Prashanth, Timothy L. Turner, Nathan B. Pincus, Marc H. Scheetz, Kelly E. R. Bachta, Alan R. Hauser

“…The use of G. mellonella to study Pseudomonas aeruginosa pathogenesis, however, is challenging because of the extreme sensitivity of larvae to this bacterium. …”
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Profiling of Somatic Mutations in Phaeochromocytoma and Paraganglioma by Targeted Next Generation Sequencing Analysis by Andrea Luchetti, Diana Walsh, Fay Rodger, Graeme Clark, Tom Martin, Richard Irving, Mario Sanna, Masahiro Yao, Mercedes Robledo, Hartmut P. H. Neumann, Emma R. Woodward, Farida Latif, Stephen Abbs, Howard Martin, Eamonn R. Maher

“…We report the first evidence for BRAF mutations in the pathogenesis of PCC/PGL/HNPGL.…”
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Identifying health risk determinants and molecular targets in patients with idiopathic pulmonary fibrosis via combined differential and weighted gene co-expression analysis by Abu Tayab Moin, Md. Asad Ullah, Jannatul Ferdous Nipa, Mohammad Sheikh Farider Rahman, Afsana Emran, Md. Minhazul Islam, Swapnil Das, Tawsif Al Arian, Mohammad Mahfuz Enam Elahi, Mukta Akter, Umme Sadea Rahman, Arnab Halder, Shoaib Saikat, Mohammad Jakir Hosen

“…Understanding the molecular mechanisms underlying IPF pathogenesis is crucial for identifying diagnostic markers and therapeutic targets.MethodsWe analyzed transcriptomic data from lung tissues of IPF patients using two independent datasets. …”
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Interleukin-32 positive immune and resident cells in kidney samples from lupus patients: a pilot study by Simona Truglia, Simona Truglia, Francesco Ciccia, Silvia Mancuso, Antonella Capozzi, Aroldo Rizzo, Francesca Romana Spinelli, Fulvia Ceccarelli, Tania Colasanti, Cristina Garufi, Francesca Miranda, Maurizio Sorice, Cristiano Alessandri, Fabrizio Conti

“…This study may indicate a possible role for IL-32 in the pathogenesis of LN.…”
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