Epstein-Barr Virus and Systemic Lupus Erythematosus by Anette Holck Draborg, Karen Duus, Gunnar Houen

“…This paper reviews EBV immunobiology and how this is related to SLE pathogenesis by illustrating uncontrolled reactivation of EBV as a disease mechanism for SLE. …”
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Brainstem and Cerebellar Involvement in Ramsay Hunt Syndrome by Vijay Letchuman, Charles D. Donohoe

“…Classic findings include the triad of ipsilateral facial paralysis, otic pain, and herpetic lesions in the sensory supply of the facial nerve. The common pathogenesis is associated with anterograde axonal reactivation of the varicella zoster virus in the geniculate ganglion. …”
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Sitagliptin: a potential drug for the treatment of COVID-19? by Bardaweel Sanaa K., Hajjo Rima, Sabbah Dima A.

“…Possible interaction of SARS-CoV-2 with DPP4 peptidase may partly contribute to the viral pathogenesis. An integrative bioinformatics approach starting with mining the biomedical literature for high confidence DPP4-protein/gene associations followed by functional analysis using network analysis and pathway enrichment was adopted. …”
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Epidemiological and Pathogenic Relationship between Sleep Apnea and Ischemic Heart Disease by Carlos Carpio, Rodolfo Álvarez-Sala, Francisco García-Río

“…Moreover, chronic intermittent hypoxia and oxidative stress have an important role in the pathogenesis of coronary disease and are also fundamental to the development of atherosclerosis and other comorbidities present in coronary artery diseases such as lipid metabolic disorders. …”
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Virulence Factors Contributing to Pathogenicity of Candida tropicalis and Its Antifungal Susceptibility Profile by Sachin C. Deorukhkar, Santosh Saini, Stephen Mathew

“…The identification of virulence attributes specific for each species and their correlation with each other will aid in the understanding of the pathogenesis of infection.…”
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Mechanism and Treatment Strategy of Osteoporosis after Transplantation by Lei Song, Xu-Biao Xie, Long-Kai Peng, Shao-Jie Yu, Ya-Ting Peng

“…Many factors contribute to the pathogenesis of OP in transplanted patients. Many mechanisms of OP have been deeply approached. …”
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VANGL2 alleviates inflammatory bowel disease by recruiting the ubiquitin ligase MARCH8 to limit NLRP3 inflammasome activation through OPTN-mediated selective autophagy. by Huaji Jiang, Yingchao Xie, Zhiqiang Hu, Jiansen Lu, Jiahuan Zhang, Hongyu Li, Ke Zeng, Wenqiang Peng, Cheng Yang, Junsheng Huang, Zelong Han, Xiaochun Bai, Xiao Yu

“…Here, we explore the role and precise mechanism of Van-Gogh-like 2 (VANGL2) during the pathogenesis of IBD. VANGL2 decreases in IBD patients and dextran sulfate sodium (DSS)-induced colitis in mice. …”
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c-Jun-N-Terminal Kinase Signaling Is Involved in Cyclosporine-Induced Epithelial Phenotypic Changes by Nicolas Pallet, Eric Thervet, Dany Anglicheau

“…Tubular epithelial cells play a central role in the pathogenesis of chronic nephropathies. Previous toxicogenomic studies have demonstrated that cyclosporine- (CsA-) induced epithelial phenotypic changes (EPCs) are reminiscent of an incomplete epithelial to mesenchymal transition (EMT) in a TGF-β-independent manner. …”
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HIV-Associated Neurotoxicity: The Interplay of Host and Viral Proteins by Sushama Jadhav, Vijay Nema

“…In-depth research in the pathogenesis of HIV has focused on various mechanisms involved in neuronal dysfunction and associated toxicities ultimately showcasing the involvement of various pathways. …”
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Mesenchymal Stromal Cells and Viral Infection by Maytawan Thanunchai, Suradej Hongeng, Arunee Thitithanyanont

“…However, the interplay between MSCs and virus is like a double-edge sword, and it also provides beneficial effects such as allowing the proliferation and function of antiviral specific effector cells instead of suppressing them, serving as an ideal tool for study of viral pathogenesis, and protecting hosts against viral challenge by using the antimicrobial activity. …”
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Advances in T Helper 17 Cell Biology: Pathogenic Role and Potential Therapy in Multiple Sclerosis by Elisabetta Volpe, Luca Battistini, Giovanna Borsellino

“…In particular, studies in MS and in its animal model (EAE, experimental autoimmune encephalomyelitis) have revealed a crucial role of Th17 cells in the pathogenesis of autoimmune demyelinating diseases in both mice and humans. …”
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Bach2: A Key Regulator in Th2-Related Immune Cells and Th2 Immune Response by Guo Liu, Feng Liu

“…However, excessive Th2 immune response leads to the pathogenesis of Th2 inflammation diseases, including asthma, allergic rhinitis, and atopic dermatitis. …”
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Inflammatory Myoglandular Polyps: A Case Series of Four Patients and Review of the Literature by Shoji Hirasaki, Hiromitsu Kanzaki, Minoru Matsubara, Seiyuu Suzuki

“…Only a small number of cases have been reported, and the pathogenesis remains unclear. Methods. We analyzed colonoscopy and histologic findings in 4 patients with IMGP. …”
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The Emerging Functions of Long Noncoding RNA in Immune Cells: Autoimmune Diseases by Keshav Raj Sigdel, Ao Cheng, Yin Wang, Lihua Duan, YanLin Zhang

“…Therefore, elucidation of the roles of lncRNAs in autoimmunity could be beneficial to understand the pathogenesis of autoimmune diseases. In this review article we attempt to highlight the recent progress regarding lncRNAs studies and summarize its role in autoimmune diseases.…”
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Metabolic and Clinical Consequences of Hyperthyroidism on Bone Density by Jagoda Gorka, Regina M. Taylor-Gjevre, Terra Arnason

“…Consequently, the impact of the above normal thyroid hormones in the pathogenesis of osteoporosis may be presently underrecognized due to the widespread effective treatments. …”
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Multisystem Myotilinopathy, including Myopathy and Left Ventricular Noncompaction, due to the MYOT Variant c.179C>T by Josef Finsterer, Claudia Stöllberger, Matthias Hasun, Korbinian Riedhammer, Mathias Wagner

“…Left ventricular hypertrabeculation/noncompaction is a myocardial abnormality of unknown etiology/pathogenesis, which is frequently associated with neuromuscular disorders or chromosomal defects. …”
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Identification of Novel Causal FBN1 Mutations in Pedigrees of Marfan Syndrome by Yueli Wang, Xiaoyan Li, Rongjuan Li, Ya Yang, Jie Du

“…Fibrillin-1 (FBN1) is the causative gene in the pathogenesis of MFS. Patients with different FBN1 mutations often present more considerable phenotypic variation. …”
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Antisynthetase syndrome with anti-glycyl tRNA synthetase antibodies in a patient with axial spondyloarthritis treated with tumor necrosis factor-α inhibitors by Maria Iacovantuono, Chiara Bonini, Ernesto Di Biase, Vinicio Magliacani, Gian Domenico Sebastiani

“…Only in one case, ASSD manifested with lung involvement, without the possible implication of TNF-α inhibitors in the pathogenesis, as it occurred concurrently with spondyloarthritis. …”
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The Role of Limbal Epithelial Stem Cells in Regulating Corneal (Lymph)angiogenic Privilege and the Micromilieu of the Limbal Niche following UV Exposure by M. Notara, A. Lentzsch, M. Coroneo, C. Cursiefen

“…Previous reports showing changes occurring in limbal epithelium during pterygium pathogenesis suggest that there is a link to stem cell damage. …”
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PPARγ as a Potential Target to Treat Airway Mucus Hypersecretion in Chronic Airway Inflammatory Diseases by Yongchun Shen, Lei Chen, Tao Wang, Fuqiang Wen

“…AMH contributes to the pathogenesis of chronic airway inflammatory diseases, and it is associated with reduced lung function and high rates of hospitalization and mortality. …”
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