Recent Advances in Pathogenesis and Anticoagulation Treatment of Sepsis-Induced Coagulopathy by Man C, An Y, Wang GX, Mao EQ, Ma L

“…This review contributes to our understanding of the pathogenesis of coagulopathy in patients with sepsis. …”
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Crohn’s Disease – The Pathogenesis of a Granulomatous Vasculitis: A Hypothesis by Andrew J Wakefield

“…Dissatisfied with traditional approaches to studying the pathogenesis of Crohn’s disease, the author and colleagues proposed and developed the hypothesis that Crohn’s disease is a granulomatous vasculitis mediated by a persistent viral infection of the mesenteric microvascular endothelium. …”
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A Comprehensive Review and Update on the Pathogenesis of Inflammatory Bowel Disease by Qingdong Guan

“…Inflammatory bowel disease (IBD) is a chronic and life-threating inflammatory disease of gastroenteric tissue characterized by episodes of intestinal inflammation. The pathogenesis of IBD is complex. Recent studies have greatly improved our knowledge of the pathophysiology of IBD, leading to great advances in the treatment as well as diagnosis of IBD. …”
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The Role of Air Pollution and Olfactory Dysfunction in Alzheimer’s Disease Pathogenesis by Louise Odendaal, Hazel Quek, Carla Cuní-López, Anthony R. White, Romal Stewart

“…Additionally, this review aims to highlight the potential mechanisms through which pollutants might instigate the development of AD and the role of the olfactory system in disease pathogenesis. Moreover, the diverse model systems employed in exploring the correlation, public health policy ramifications, and prospective directions for future research will be discussed.…”
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Role of microglia in the pathogenesis of multiple sclerosis and links to immunomodulatory therapy by P. Valiukevičius, R. Liutkevičienė, R. Balnytė

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Recent Advances: The Imbalance of Cytokines in the Pathogenesis of Inflammatory Bowel Disease by Qingdong Guan, Jiguo Zhang

“…Recent studies show the beneficial effects of anticytokine treatments to IBD patients, and multiple novel cytokines are found to be involved in the pathogenesis of IBD. In this review, we will discuss the recent advances of novel biologics in clinics and clinical trials, and novel proinflammatory and anti-inflammatory cytokines found in IBD with focusing on IL-12 family and IL-1 family members as well as their relevance to the potential therapy of IBD.…”
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The Pathogenesis of Necroptosis-Dependent Signaling Pathway in Cerebral Ischemic Disease by Yang Xu, Ji Zhang, Lingsong Ma, Shoucai Zhao, Shizun Li, Tingting Huang, Zhaohu Chu

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Programmed Cell Death Pathways in the Pathogenesis of Systemic Lupus Erythematosus by Fangyuan Yang, Yi He, Zeqing Zhai, Erwei Sun

“…Increasing evidence has demonstrated the important role of programmed cell death in SLE pathogenesis. When apoptosis encounters with defective clearance, accumulated apoptotic cells lead to secondary necrosis. …”
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Current Overview of Allergens of Plant Pathogenesis Related Protein Families by Mau Sinha, Rashmi Prabha Singh, Gajraj Singh Kushwaha, Naseer Iqbal, Avinash Singh, Sanket Kaushik, Punit Kaur, Sujata Sharma, Tej P. Singh

“…Pathogenesis related (PR) proteins are one of the major sources of plant derived allergens. …”
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Developmental and Epileptic Encephalopathy: Pathogenesis of Intellectual Disability Beyond Channelopathies by Alexandra D. Medyanik, Polina E. Anisimova, Angelina O. Kustova, Victor S. Tarabykin, Elena V. Kondakova

“…We focus on three major mechanisms of intellectual disability in DEE and describe several recently identified genes involved in the pathogenesis of DEE.…”
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Cardiac Autonomic Control Mechanisms in the Pathogenesis of Chagas' Heart Disease by Diego F. Dávila, Jose H. Donis, Gabriela Arata de Bellabarba, Vanesa Villarroel, Francisco Sanchez, Lisbeth Berrueta, Siham Salmen, Barbara Das Neves

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Novel Roles of the Picornaviral 3D Polymerase in Viral Pathogenesis by Jason Kerkvliet, Ramakrishna Edukulla, Moses Rodriguez

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Protective Role of Glutathione and Nitric Oxide Production in the Pathogenesis of Pterygium by Fidelina Parra, Alexander Kormanovski, Gustavo Guevara-Balcazar, María del Carmen Castillo-Hernández, Antonio Franco-Vadillo, Mireille Toledo-Blas, Rosa Adriana Jarillo-Luna, Eleazar Lara-Padilla

“…Objective. In the pathogenesis of pterygium, the protective role of glutathione and nitric oxide production is unclear. …”
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Functional morphology of digestive organs of newborn calves and pathogenesis of escherichiosis by S. M. Suleymanov

“…This paper presents results of experimental studies carried out at the FSBSI “All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy”.T he aim of the work was to conduct complex morphological studies using modern methods for a deeper understanding of escherichiosis etiology and pathogenesis. For that, pathological samples were collected from 28 1–10 day-old calves diagnosed with colibacteriosis at the initial disease stage, demonstrating pronounced clinical signs and having the terminal stage of the disease. …”
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The pathogenesis of COVID-19: Hypercoagulation and D-dimer in thrombotic complications by Leonid DUBEY, Halyna LYTVYN, Olha DOROSH, Nataliya DUBEY, Olena KOZLOVA, Michal PRUC, Nina KUBIKOWSKA, Lukasz SZARPAK, Kavita BATRA, Francesco CHIRICO, Gabriella NUCERA, Svitlana DOAN, Uljana SHEVTSIV

“…This narrative review aims to elucidate the pathogenesis of COVID-19, which will further help in precise diagnosis and treatment.…”
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Sphingolipid metabolites involved in the pathogenesis of atherosclerosis: perspectives on sphingolipids in atherosclerosis by Fufangyu Zhao, Mingyan Shao, Mingrui Li, Tianxing Li, Yanfei Zheng, Wenlong Sun, Cheng Ni, Lingru Li

“…Abstract Atherosclerosis, with its complex pathogenesis, is a leading underlying cause of many cardiovascular diseases, which are increasingly prevalent in the population. …”
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Hepatic macrophages in liver fibrosis: pathogenesis and potential therapeutic targets by Hai Li, Hong You, Jidong Jia, Xu Fan

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Caspase-11 Modulates Inflammation and Attenuates Toxoplasma gondii Pathogenesis by Sheryl L. Coutermarsh-Ott, John T. Doran, Caroline Campbell, Tere M. Williams, David S. Lindsay, Irving C. Allen

“…Asc−/− mice demonstrated increased disease pathogenesis during the acute phase of T. gondii infection, whereas Casp11−/− mice demonstrated significantly attenuated disease pathogenesis and reduced inflammation. …”
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Single cell transcriptome profiling reveals pathogenesis of bullous pemphigoid by Guirong Liang, Chenjing Zhao, Qin Wei, Suying Feng, Yetao Wang

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Unraveling the pathogenesis of Barrett’s esophagus and esophageal adenocarcinoma: the “omics” era by Alberto Barchi, Giuseppe Dell’Anna, Giuseppe Dell’Anna, Luca Massimino, Luca Massimino, Francesco Vito Mandarino, Edoardo Vespa, Edi Viale, Sandro Passaretti, Vito Annese, Vito Annese, Alberto Malesci, Alberto Malesci, Silvio Danese, Silvio Danese, Federica Ungaro

“…BE is the consequence of chronic reflux disease and has a potential progression burden to esophageal adenocarcinoma (EAC). The pathogenesis of BE and EAC has been extensively studied but not completely understood, and it is based on two main hypotheses: “transdifferentiation” and “transcommitment”. …”
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