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1161
Penile Livedoid Vasculopathy: First Reported Case
Published 2023-01-01“…Livedoid vasculopathy is a thromboocclusive cutaneous vasculopathy manifested by livedoid changes, atrophie blanche, and ulceration. The pathogenesis is speculated to involve increasing coagulation or impaired thrombolysis leading to the occlusion of dermal blood vessels with fibrin thrombi. …”
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1162
The Role of p38 MAPK in the Aetiopathogenesis of Psoriasis and Psoriatic Arthritis
Published 2013-01-01“…This review discusses the current data suggesting a crucial role for p38 MAPK in the pathogenesis of these disorders.…”
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1163
Oxidative stress in viral hepatitis
Published 2024-04-01“…Accumulating evidence suggests that oxidative stress (OS) plays a pivotal role in the pathogenesis and progression of viral hepatitis. OS occurs due to a disproportion between reactive oxygen species (ROS) generation and antioxidant protection, resulting in damage to cells and tissues. …”
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1164
Melatonin and its therapeutic prospects in gastroenterology
Published 2018-08-01“…The melatonin role in pathogenesis and prognosis of digestive diseases is covered. …”
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1165
Dietary content and eating behavior in ulcerative colitis: a narrative review and future perspective
Published 2025-01-01“…Current research into UC pathogenesis focuses on the complex interplay of genetic and environmental factors with the immune system and gut microbiome, leading to disruption of the intestinal barrier. …”
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1166
The link between optic neuritis and multiple sclerosis. Literature review
Published 2021-03-01“…Some aspects of epidemiology, etiology, pathogenesis, clinical signs, possibilities of diagnosis and treatment of optic neuritis together with the evaluation of the risk of multiple sclerosis development are discussed in this article. …”
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1167
Capsule Endoscopy for Portal Hypertensive Enteropathy
Published 2016-01-01“…Portal hypertensive enteropathy (PHE) is a mucosal abnormality of the small bowel that is observed in patients with portal hypertension (PH) and can lead to gastrointestinal bleeding and anemia. The pathogenesis is still not completely understood. The introduction of new endoscopic methods, including capsule endoscopy (CE) or balloon-assisted enteroscopy, has increased the detection of these abnormalities. …”
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1168
ABO Blood Groups and Cardiovascular Diseases
Published 2012-01-01“…The role of blood group antigens in the pathogenesis of various cardiovascular disorders remains a fascinating subject with potential to lead to novel therapeutics and prognostics and to reduce the global burden of cardiovascular diseases.…”
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1169
Asymmetric Dimethyl Arginine as a Biomarker of Atherosclerosis in Rheumatoid Arthritis
Published 2018-01-01“…Asymmetric dimethylarginine is gaining attention for its implication in the pathogenesis of endothelial dysfunction and as biomarkers of subclinical atherosclerosis. …”
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1170
Leukocyte migration in experimental inflammatory bowel disease
Published 1997-01-01“…The influx of neutrophils, monocytes and lymphocytes into inflamed tissue is important in the pathogenesis of chronic inflammatory bowel disease. The importance of each of these groups of adhesion molecules in chronic inflammatory bowel disease, either in human disease or in animal models, will be discussed below. …”
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1171
A pan-orthohantavirus human lung xenograft mouse model and its utility for preclinical studies.
Published 2025-01-01“…This pan-orthohantavirus model will facilitate progress in the fundamental understanding of pathogenesis and virus-host interactions for orthohantaviruses. …”
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1172
Successful sequential therapy with rituximab and telitacicept in refractory Anti-NMDA receptor encephalitis and MOG-associated demyelination: a case report and literature review
Published 2025-02-01“…Clinical management of the rare and complex overlapping syndrome of MOG-antibody disease and anti-NMDAR encephalitis (MNOS), which has an uncertain pathogenesis and a high risk of recurrence, is highly challenging. …”
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1173
Postmastectomy-Postirradiation Atypical Vascular Lesion of the Skin: Report of 2 Cases
Published 2012-01-01“…The newer modalities of radiation therapy may be contributory to the pathogenesis. More studies have to be done in this area to prove the causal relationship. …”
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1174
Defects in skeletal muscle subsarcolemmal mitochondria in a non-obese model of type 2 diabetes mellitus.
Published 2017-01-01“…The current study investigated the role of the subpopulations of mitochondria in the pathogenesis of insulin resistance in the absence of obesity. …”
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1175
A Patient with Double-Negative VGKC, Peripheral Nerve Hyperexcitability, and Central Nervous System Symptoms: A Postinfectious Autoimmune Disease
Published 2020-01-01“…In the setting of anti-VGKC positivity, it seems likely that anti-VGKC contributed to the pathogenesis of the patient’s symptoms of nerve hyperexcitability and that the disease was caused by an acquired autoimmune effect on the neuronal kinetics of VGKC. …”
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1176
Nephronophthisis: A Genetically Diverse Ciliopathy
Published 2011-01-01“…In this paper, we discuss the latest understanding in the molecular and cellular pathogenesis of NPHP. We suggest an appropriate clinical management plan and screening programme for individuals with NPHP and their families.…”
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1177
Baricitinib Successfully Treated a Teenager with Refractory Livedoid Vasculopathy: A Case Report and Literature Review
Published 2025-02-01“…Chenxi Liu, Ying-Ying Jin, Xiqiong Han, Hua Huang, Shengfang Bao, Xuemei Xu, Liping Wang, Yanliang Jin Department of Rheumatology and Immunology, Shanghai Children’s Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, 200127, People’s Republic of ChinaCorrespondence: Yanliang Jin, Email jinyanliang@scmc.com.cnBackground: The pathogenesis is of livedoid vasculopathy (LV)—a rare, chronic, and recurrent cutaneous vascular obstructive disease—is not fully understood. …”
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1178
Genes Involved in the Biosynthesis and Transport of Acinetobactin in
Published 2015-03-01“…A recent study showed that entA, located outside of the acinetobactin gene cluster, plays important roles in the biosynthesis of the acinetobactin precursor DHBA and in bacterial pathogenesis. Therefore, understanding the genes that are associated with the biosynthesis and transport of acinetobactin in the bacterial genome is required. …”
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1179
Exploring Long Noncoding RNAs in Glioblastoma: Regulatory Mechanisms and Clinical Potentials
Published 2018-01-01“…Molecular mechanisms underlying the pathogenesis and progression of GBMs with potential diagnostic and therapeutic value have been explored industriously. …”
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1180
Osteogenesis Imperfecta (Type IV) with Dental Findings in Siblings
Published 2011-01-01“…Genetic factors play a very important role in the pathogenesis of OI either as a dominant or recessive factor. …”
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