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1121
Identification of sepsis-associated encephalopathy biomarkers through machine learning and bioinformatics approaches
Published 2024-12-01“…These findings provide insights into SAE pathogenesis and suggest potential therapeutic targets.…”
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1122
The Enteric Nervous System in Intestinal Inflammation
Published 1996-01-01“…Since about the 1950s nerves in the wall of the intestine have been postulated to play a role in the pathogenesis of inflammatory bowel disease (IBD). Human and animal studies examining the role of nerves in intestinal inflammation are the focus of this review. …”
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1123
Raoultella Planticola Bacteremia Following Consumption of Seafood
Published 2014-01-01“…Recent chemotherapy, proton pump inhibitor use and altered biliary flow secondary to hepatic metastases may have been contributing factors to the pathogenesis of disease.…”
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1124
Research progress on the mechanisms of apolipoprotein E in Alzheimer’s disease
Published 2025-01-01“…Alzheimer’s disease (AD) is a degenerative disorder of the central nervous system that predominantly affects the elderly.The Apolipoprotein E (ApoE) gene is identified as the most significant genetic factor associated with AD.This article reviews current findings on the relationship between ApoE and AD, the impact of APOE gene polymorphisms on AD, the interaction between ApoE and other pathogenic factors, and the role of ApoE in AD.Additionally, it discusses the diagnosis and treatment of AD to enhance the understanding of its pathogenesis and to provide new perspectives for the prevention and management of the disease.…”
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1125
Too many cooks in the kitchen: HPV driven carcinogenesis – The result of collaboration or competition?
Published 2025-06-01“…At the core of Papillomavirus pathogenesis sits three virally encoded oncoproteins: E5, E6, and E7. …”
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1126
Dandy-Walker Malformation Presenting with Psychological Manifestations
Published 2016-01-01“…Dandy-Walker malformation, which is a congenital malformation of the cerebellum, is documented in literature to be associated with psychotic symptoms, obsessive compulsive symptoms, mood symptoms, hyperactivity, and impulsive behavior. The pathogenesis of psychiatric symptoms in Dandy-Walker malformation is thought to be due to disruption of the corticocerebellar tracts, resulting in what is known as cerebellar cognitive affective syndrome. …”
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1127
Hypocomplementemic urticarial vasculitis syndrome: A disease with many faces
Published 2019-01-01“…Hypocomplementemic urticarial vasculitis syndrome (HUVS) is a rare autoimmune disease process where the exact pathogenesis is not known. It is an independent immunological condition affecting multiple organ systems. …”
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1128
Role of sirtuin 1 (SIRT1) gene polymorphisms in pituitary adenoma development. Literature review
Published 2018-06-01“…In this article, we will review the PA classification’s innovation, etiology, pathogenesis, SIRT1 polymorphisms and their significance for PA development. …”
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1129
Toward Molecular Level of the “Salmonella-Victim” Ecology, Genetics, and Evolution
Published 2004-01-01“…In this article, some key findings concerning ecology, molecular ecology, and cell level of the Salmonella infection genetics are summarized and interpreted from the viewpoint of evolutionary theory with certitude that this approach can help to decipher the undiscovered secrets of Salmonella infections epidemiology and pathogenesis, as well as the clinical course and severity, and to select ways for fighting against Salmonella.…”
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1130
Contribution of Genetic Factors to Sjögren’s Syndrome and Sjögren’s Syndrome Related Lymphomagenesis
Published 2015-01-01“…We aimed to summarize the current evidence related to the contributory role of genetic factors in the pathogenesis of Sjögren’s syndrome (SS) and SS-related lymphoma. …”
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1131
Uncommon Progression of an Extradural Spinal Meningioma
Published 2014-01-01“…In addition we discuss the pathogenesis of these tumors and the potential pitfalls in differential diagnosis and review the relevant literature concerning their treatment and outcome.…”
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1132
Global stability of an HIV-1 model with distributed intracellular delays and a combination therapy
Published 2010-05-01“…Global stability is analyzed for a general mathematical model of HIV-1 pathogenesis proposed by Nelson and Perelson [11]. The general model include two distributed intracellular delays and a combination therapy with a reverse transcriptase inhibitor and a protease inhibitor. …”
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1133
Circulating Cytokine Levels as Markers of Inflammation in Philadelphia Negative Myeloproliferative Neoplasms: Diagnostic and Prognostic Interest
Published 2015-01-01“…In this review, we present the current knowledge on alteration of circulating cytokine profiles in MPNs and their role in myelofibrosis pathogenesis. Phenotypic correlation, prognostic value of cytokines, and impact of JAK inhibitors are also discussed.…”
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1134
Concurrent B Cell Acute Lymphoblastic Lymphoma/Leukemia and Monoclonal B Cell Lymphocytosis: A Case Report with Extensive Molecular Analysis
Published 2022-01-01“…These findings may stimulate further research to clarify the pathogenesis of hematologic neoplasms.…”
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1135
Diffuse Melanosis and Ascites due to Metastatic Malignant Melanoma
Published 2008-01-01“…We discuss briefly the current evidence on pathogenesis of melanosis arising from metastatic melanoma.…”
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1136
Predicting, Treating and Preventing Postoperative Recurrence of Crohn’s Disease: The State of the Field
Published 2011-01-01“…Unfortunately, postsurgical remission tends to be short lived; a significant number of patients experience clinical relapse and many require additional operations. The pathogenesis of this postoperative recurrence is poorly understood and, currently, there are no reliable tools to predict when and in whom the disease will recur. …”
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1137
Correlation between the Neutrophil-to-Lymphocyte Ratio and Multiple Sclerosis: Recent Understanding and Potential Application Perspectives
Published 2022-01-01“…Low-grade systemic inflammation has been considered to lead to pathogenesis owing to the amplification of pathogenic immune response activation. …”
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1138
A Critical Appraisal on the Role of Varicocele in Male Infertility
Published 2012-01-01“…This paper reviews the most recent data available on the pathogenesis, diagnosis, and management of varicocele with regard to male infertility.…”
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1139
Developments in research on the relationship between oral-gut microbes and respiratory diseases
Published 2024-12-01“…Microbial transmission between the mouth and intestines can shape or reshape the microbial ecosystem in the two habitats, ultimately regulating the pathogenesis of the disease. The dysbiosis of the oral-gut microbiota axis can have a significant impact on related diseases such as respiratory diseases. …”
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1140
Sebaceous Lymphadenoma of Parotid: Imaging, Cytological, and Histological Findings in Detail
Published 2018-01-01“…Few case reports have been published in literature about their pathogenesis and accompanying malignant lesions. The cytological and imaging findings have been dealt with in some articles. …”
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