Mixed Large Cell Neuroendocrine Carcinoma of the Ovary: Report of a Rare Case by Ilias Galanis, Georgios Floros, Maria Sotiria Bompoula, Christophoros Theodoropoulos

“…LCNC (large cell neuroendocrine carcinomas) of the ovary is a rare aggressive tumor entity of the genital tract. Its pathogenesis, origin, and prognosis have not been fully elucidated, since there are a limited number of cases reported in literature. …”
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Macrophage-Derived Biomarkers of Idiopathic Pulmonary Fibrosis by E. Bargagli, A. Prasse, C. Olivieri, J. Muller-Quernheim, P. Rottoli

“…Several pathogenetic mechanisms have been hypothesized on the basis of the fibrotic lung damage occurring in this disease, and a potential profibrotic role of activated alveolar macrophages and their mediators in the pathogenesis of IPF was recently documented. This paper focuses on recent literature on potential biomarkers of IPF derived from activated alveolar macrophages. …”
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Molecular Targets for the Treatment of Juvenile Myelomonocytic Leukemia by Xiaoling Liu, Himalee Sabnis, Kevin D. Bunting, Cheng-Kui Qu

“…Significant advances in our understanding of the genetic defects and the pathogenesis of juvenile myelomonocytic leukemia (JMML) have been achieved in the last several years. …”
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Cardiovascular and Renal Links along the Cardiorenal Continuum by José A. García-Donaire, Luis M. Ruilope

“…Such interactions represent the pathogenesis for a clinical condition called cardiorenal syndrome. …”
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Antioxidants in Kidney Diseases: The Impact of Bardoxolone Methyl by Jorge Rojas-Rivera, Alberto Ortiz, Jesus Egido

“…New drugs targeted to the pathogenesis and mechanisms of progression of these diseases beyond RAAS inhibition are needed. …”
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Renovascular disease. A contemporary approach to the diagnosis and treatment by V.Yu. Kundin, M.V. Satyr, A.V. Khokhlov, A.G. Mazur, I.V. Noverko, M.V. Shymanko

“…The article reviews etiology and pathogenesis, clinical manifestations and diagnosis of the renovascular disease. …”
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Colorectal Cancer and Basement Membranes: Clinicopathological Correlations by Charalampos C. Mylonas, Andreas C. Lazaris

“…BM seems to play a role in the pathogenesis of colorectal cancer, so BM alterations may have prognostic significance as well. …”
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INTESTINAL MICROBIOME - A LEADING FACTOR IN HUMAN HEALTH AND DISEASES by E. Blum Hubert

“…Summary: Major advances in molecular and cell biology significantly improved our understanding of disease pathogenesis as well as in novel strategies for the diagnosis, therapy and prevention of human diseases. …”
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Carbohydrate intolerance by V. O. Kaybysheva, Ye. K. Baranskaya

“…To present the modern concept on etiology and pathogenesis of food intolerance, to analyze the modern strategy of diagnosis and treatment of carbohydrate intolerance. …”
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Cardiac Hypertrophy and Fibrosis in the Metabolic Syndrome: A Role for Aldosterone and the Mineralocorticoid Receptor by Eric E. Essick, Flora Sam

“…There has been much investigation into the role that an increase in the renin-angiotensin-aldosterone system (RAAS) plays in the pathogenesis of metabolic syndrome and in particular, how aldosterone mediates left ventricular hypertrophy and increased cardiac fibrosis via its interaction with the mineralocorticoid receptor (MR). …”
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Technologies for Proteome-Wide Discovery of Extracellular Host-Pathogen Interactions by Nadia Martinez-Martin

“…The identification of the host and pathogen extracellular molecules and their interaction networks is fundamental to understanding tissue tropism and pathogenesis and to inform the development of therapeutic strategies. …”
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A Rare Colocalization of Lichen Planus and Vitiligo by David Veitch, Georgios Kravvas, Sian Hughes, Christopher Bunker

“…Rather, the association is likely to be multifactorial in its pathogenesis.…”
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Primary Lymphangioma of the Tonsil: A Case Report by Dimitrios G. Balatsouras, Alexandros Fassolis, George Koukoutsis, Panayotis Ganelis, Antonis Kaberos

“…Lymphangiomas are rare congenital tumors of the lymphatic system, and tonsillar lymphangioma is an extremely rare occurrence. Its pathogenesis is uncertain, but history, clinical examination, and histological examination should establish the diagnosis. …”
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Characteristics, pathogenic and therapeutic role of gut microbiota in immunoglobulin A nephropathy by Kaijin Yao, Lingqian Zheng, Wenmin Chen, Yina Xie, Chunling Liao, Tianbiao Zhou

“…It is now believed that the pathogenesis of IgAN is the mesangial deposition of immune complex containing galactose-deficient IgA1, resulting in glomerular injury. …”
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Cytokines as Therapeutic Targets for the Gastrointestinal Manifestations of Scleroderma by Jennifer M Raoul, Monica Verma, Ernest Tan, Theresa C Peterson

“…It has significance for gastroenterologists because the gastrointestinal tract is involved in 90% of SSc patients, who often present with esophageal dysfunction. Though the exact pathogenesis of SSc is unknown, there is increasing evidence supporting an immune mechanism. …”
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The Mechanosensory Role of Primary Cilia in Vascular Hypertension by Surya M. Nauli, Xingjian Jin, Beerend P. Hierck

“…The basic and clinical perspectives on primary cilia are discussed with regard to the pathogenesis of hypertension in PKD.…”
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A Rare Case Report: Primary Vulvar Adenocarcinoma of Mammary Gland Type by Dai X, Lei H, Jie R

“…Further studies are needed to better understand the pathogenesis and clinical characteristics of vulvar AMGT.Keywords: vulva, adenocarcinoma, mammary gland type, differential diagnosis…”
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Calcium-mediated regulation of mitophagy: implications in neurodegenerative diseases by Fivos Borbolis, Christina Ploumi, Konstantinos Palikaras

“…Furthermore, we discuss how disruptions in calcium homeostasis impair mitophagy, contributing to mitochondrial dysfunction and the pathogenesis of common neurodegenerative diseases.…”
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The important practical results and modern lines in studying diseases of the stomach and duodenum (Review of the Seventeenth Russian Gastroenterological Week proceedings, October,... by I. V. Mayev, A. A. Samsonov, N. G. Andreyev, D. N. Andreyev

“…The further accumulation and analysis of data on etiology, pathogenesis and clinical features of diseases of the stomach and duodenum based on the advanced methods of investigation. …”
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Reverse Cholesterol Transport Pathway and Cholesterol Efflux in Diabetic Retinopathy by Xinyuan Zhang, Kaiyue Wang, Ling Zhu, Qiyun Wang

“…However, the precise underlying mechanism of the RCT pathway in the pathogenesis of DR is still not fully understood. This review focused on cholesterol metabolism, with a particular emphasis on the RCT pathway and its correlation with the development of DR. …”
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