The Role of Microglia and Matrix Metalloproteinases Involvement in Neuroinflammation and Gliomas by Helen Könnecke, Ingo Bechmann

“…Matrix metalloproteinases (MMPs) are involved in the pathogenesis of neuroinflammatory diseases (such as multiple sclerosis) as well as in the expansion of malignant gliomas because they facilitate penetration of anatomical barriers (such as the glia limitans) and migration within the neuropil. …”
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X-Chromosome Inactivation and Related Diseases by Zhuo Sun, Jinbo Fan, Yang Wang

“…Here, we review representative diseases in terms of their definition, symptoms, and XCI’s role in the pathogenesis of these diseases.…”
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Inflammation as a Driver of Clonal Evolution in Myeloproliferative Neoplasm by Angela G. Fleischman

“…Our understanding of inflammation’s role in the pathogenesis of myeloproliferative neoplasm (MPN) is evolving. …”
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Cladophialophora bantiana Brain Abscess in an Immunocompetent Patient by Sanjay G. Revankar

“…Additional studies to understand the pathogenesis of this infection and to improve outcomes are needed.…”
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Stenotrophomonas maltophilia – A Threatening Nosocomial Pathogen by Ruchita Gawande, Suvarna Sande

“…It can cause pneumonia, septicemia, meningitis, urinary tract, and wound infections, and is associated with high mortality in immune-compromised patients. Pathogenesis in S. maltophilia infections is an outcome of multiple virulence factors, including outer membrane lipopolysaccharide, extracellular enzymes, porins, pilli, biofilm formation, motility, and small colony variants, among others. …”
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Stem cell therapy for the treatment of psychiatric disorders: a real hope for the next decades by Rosa Villanueva

“…All of them share common biomedical features, such as complex and variable genetic substrates, significant susceptibility to environmental changes, and insufficient knowledge of their pathogenesis. In addition, the responsiveness of patients to pharmacological treatment is heterogeneous, and in some cases, no treatment is available. …”
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Modern approaches to functional dyspepsia treatment by A. A. Sheptulin

“…Investigation of FD pathogenesis should be continued that will provide more differentiated treatment approach and improve the results.…”
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Spectrum of spondyloarthritis by Himanshu Pathak, Karl Gaffney

“…Spondyloarthritis (SpA) comprises a group of related diseases which share similar pathogenesis and clinical manifestations. Although the occurrence of SpA spectrum disorders has been known for some time, it was only in the latter half of the twentieth century that the concept of SpA was formally defined. …”
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The Influence of Nutrients on Inflammatory Bowel Diseases by Sara Jarmakiewicz-Czaja, Dominika Piątek, Rafał Filip

“…Inflammatory bowel diseases is a group of inflammatory diseases. The pathogenesis of diseases is multifactorial, which may include a Western-type diet. …”
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Exploration of Five Flaccidities in <italic>Medical Formulae Investigations of Flaccidity</italic> by Qing LIN, Guangwen WU

“…In the part of the monograph related to flaccidity, the etiology, pathogenesis, prescription and methodology of"five flaccidities"which are closely connected with diseases of heart, lung, liver and kidney have been described in detail. …”
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A Case Report of Chlamydia psittaci Infective Endocarditis Complicated With Pneumonia by Dongmei Zhao, Li Zhang, Qiulin Sun, Jun Cheng

“…Discussion on the pathogenesis, diagnosis, and treatment of this disease based on recent literature reports aimed to improve the prognosis of similar patients and enhance the understanding of clinicians.…”
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Gastroesophageal reflux disease and functional dyspepsia: clinical efficacy and safety of prokinetic choice by D. I. Trukhan

“…Motility disorder of gastroesophageal zone plays a leading part in pathogenesis of these diseases that assumes application prokinetics as a baseline therapy. …”
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METTL3/miR-192-5p/SCD1 Axis Regulates Lipid Metabolism to Affect T Cell Differentiation in Asthma by Zhengrong Chen, Dingwei Yan, Suyu Guo, Yiyi Song, Xinxing Zhang, Wenjing Gu, Heting Dong, Li Huang

“…This study may provide novel insights into the pathogenesis of asthma and a new treatment strategy.…”
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Anaplastic Sarcoma of the Kidney by Apostolos P. Labanaris, Vahudin Zugor, Robert Smiszek, Reinhold Nützel, Reinhard Kühn

“…Although of unknown origin and pathogenesis, treating such a tumor as if it was anaplastic Wilms' tumor seems to be the only therapeutic solution at the present time. …”
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The Impact of Antidiabetic Agents on Sarcopenia in Type 2 Diabetes: A Literature Review by Chen-Ning Wu, Kai-Jen Tien

“…This study reviewed the literature on the pathogenesis of sarcopenia in diabetes mellitus and the current understanding of whether antidiabetic agents contribute positively or negatively to sarcopenia and muscle wasting.…”
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Roles and Mechanisms of Regulated Necrosis in Corneal Diseases: Progress and Perspectives by Wanying Lin, Minting Chen, Yacouba Cissé, Xiaofeng Chen, Lang Bai

“…Various forms of regulated necrosis, particularly pyroptosis, necroptosis, and ferroptosis, have been implicated in the pathogenesis of corneal disease. Regulated necrosis of corneal cells enhances inflammatory reactions in the adjacent corneal tissues, leading to recurrence and aggravation of corneal disease. …”
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An Unusual Example of Asperigillus Species Lung Disease by Richard L Pardy, Martha Grymaloski, Blair AM Walker

“…The role of infected bullet fragments in the pathogenesis of hemoptysis in this patient is discussed.…”
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Extensive Macular Atrophy with Pseudodrusen Imaged with OCT Angiography by Jaclyn L. Kovach

“…Extensive macular atrophy with pseudodrusen is a rare clinical entity and a new extreme phenotype of macular degenerations that could shed more light on the role of pseudodrusen and choriocapillaris compromise in the pathogenesis of AMD.…”
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Antimicrobial susceptibility and epidemiological types of Legionella pneumophila human isolates from Italy (1987–2020) by Maria Scaturro, Alessio Lanni, Fabiola Mancini, Antonietta Girolamo, Silvia Fillo, Andrea Ciammaruconi, Florigio Lista, Clementina Elvezia Cocuzza, Rosario Musumeci, Christophe Ginevra, Ghislaine Descours, Sophie Jarraud, Jessica Iera, Paolo Visca, Maria Luisa Ricci

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Association between the ABCC11 gene polymorphism-determined earwax properties and external auditory canal microbiota in healthy adults by Yasunobu Amari, Masahiro Hosonuma, Takuya Mizukami, Junya Isobe, Yuki Azetsu, Eiji Funayama, Yuki Maruyama, Toshiaki Tsurui, Kohei Tajima, Aya Sasaki, Yoshitaka Yamazaki, Ryota Nakano, Yutaka Sano, Atsushi Ishida, Tatsuya Nakanishi, Seiji Mochizuki, Yuri Yoshizawa, Sumito Kumagai, Sakiko Yasuhara, Kakei Ryu, Tatsunori Oguchi, Atsuo Kuramasu, Kiyoshi Yoshimura, Takehiko Sambe, Sei Kobayashi, Naoki Uchida

“…Future studies should focus on ABCC11 gene polymorphisms to elucidate the pathogenesis of ear diseases and develop therapeutic methods.…”
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