Exploring the role of inflammatory biomarkers in trigeminal neuralgia by Shenglong Lai, Haiyang Li, Yazhou Xing, Du Wu, Lin Wang, Qinghua Liang

“…Inflammation has been suggested as a contributing factor to TN pathogenesis. This study investigates the causal relationship between inflammatory biomarkers, including 41 circulating inflammatory cytokines, C-reactive protein (CRP), and procalcitonin (PCT), and TN using Mendelian randomization (MR) analysis. …”
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No Little Feet: Managing Pseudocyesis in a Homeless, Acutely Manic Patient with Schizoaffective Disorder, Bipolar Type by Talitha West, Omotola Ajibade, Anthony Fontanetta, Samreen Munir

“…Although the etiology, pathogenesis, diagnosis, and management of pseudocyesis are poorly understood, it manifests with real symptoms, which may complicate both the patient’s perspective about her condition and the medical and psychiatric teams’ approach to the patient. …”
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Mechanisms of Neuroprotection by Protein Disulphide Isomerase in Amyotrophic Lateral Sclerosis by Adam K. Walker, Julie D. Atkin

“…Recently, endoplasmic reticulum (ER) stress was identified as an early and central feature in ALS disease models as well as in human patient tissues, indicating that ER stress could be an important process in disease pathogenesis. One important chaperone induced by ER stress is protein disulphide isomerase (PDI), which is both upregulated and posttranslationally inhibited by S-nitrosylation in ALS. …”
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Advances in personalized gastroenterology and hepatology 2016 by E. Blum Hubert

“…Molecular and cell biology have resulted in major advances in our understanding of disease pathogenesis as well as in novel strategies for the diagnosis, therapy and prevention of human diseases. …”
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Primary Malignant Fibrous Histiocytoma: A Rare Case by Anastasios Katsourakis, George Noussios, Iosif Hadjis, Neofitos Evangelou, Efthimios Chatzitheoklitos

“…MFH of the small intestine is an extremely rare neoplasm with an aggressive biological behaviour. In this paper, pathogenesis, natural history, and treatment are reviewed.…”
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Three Cases with Visual Hallucinations following Combined Ocular and Occipital Damage by Bogusław Paradowski, Edyta Kowalczyk, Justyna Chojdak-Łukasiewicz, Aleksandra Loster-Niewińska, Monika Służewska-Niedźwiedź

“…In two cases, diagnosis showed coexistence of occipital lobe damage with ocular damage, while in the third case it showed occipital lobe damage with retrobulbar optic neuritis. Theories of pathogenesis and the neuroanatomical basis of complex visual hallucinations are discussed and supported by literature review.…”
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Epidermoid Causing Ischemic Stroke in the Brainstem by Raghvendra Ramdasi, Amit Mahore, Abhijeet Kulkarni, Vithal Rangarajan, Manoj Patil, Juhi Kawale

“…We have also reviewed the literature and pathogenesis of stroke caused by intracranial tumors.…”
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A Review of Intraocular Pressure (IOP) and Axial Myopia by Dongyan Zhang, Liyin Wang, Le Jin, Yingying Wen, Xuhong Zhang, Liyue Zhang, Hong Zhu, Ziyu Wang, Xin Yu, Chen Xie, Jianping Tong, Ye Shen

“…The pathogenesis of myopia is driven by genetic and environmental risk factors. …”
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Organ-based characterization of B cells in patients with systemic lupus erythematosus by Yunan Wang, Rui Zhao, Qian Liang, Shiwen Ni, Mei Yang, Liwei Qiu, Juan Ji, Zhifeng Gu, Chen Dong

“…Systemic lupus erythematosus (SLE) is a chronic, inflammatory, and progressive autoimmune disease. The unclear pathogenesis, high heterogeneity, and prolonged course of the disease present significant challenges for effective clinical management of lupus patients. …”
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A comparison of Bartonella henselae infection in immunocompetent and immunocompromised mice. by Rebekah L Bullard, Mercedes Cheslock, Shiva Kumar Goud Gadila, Ricardo G Maggi, Edward B Breitschwerdt, Ahmad A Saied, Monica E Embers

“…The dearth of knowledge regarding diagnosis, treatment and pathogenesis of this disease can be partially attributed to the lack of a reliable small animal model for the disease. …”
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Sex Differences in Energy Metabolism Need to Be Considered with Lifestyle Modifications in Humans by Betty N. Wu, Anthony J. O'Sullivan

“…Moreover, elucidating the regulatory role of hormones in energy homeostasis is important for understanding the pathogenesis of obesity and perhaps in the future may lead to ways to reduce body fat with less energy restriction.…”
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Role of phage therapy in acute gastroenteritis by Somaieh Sabzali, Setareh Pazhouhnia, Kiana Shahzamani, Peyman Adibi Sedeh

“…Dysbiosis, or an imbalance in the gut microbiota, has been associated with the pathogenesis of several diseases, ranging from intestinal disorders such as inflammatory bowel disease to extra-intestinal conditions such as metabolic and neurological disorders. …”
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Hybrid Clinical and Histopathological Pattern in Annular Lesions: An Overlap between Annular Elastolytic Giant Cell Granuloma and Granuloma Annulare? by Felipe Ladeira de Oliveira, Luisa Kelmer Côrtes de Barros Silveira, Alice de Miranda Machado, José Augusto da Costa Nery

“…Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of unclear pathogenesis which belongs to the group of disorders in the skin and elastic fibers with similar clinical features of granuloma annulare (GA). …”
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Dupilumab-induced psoriasis in a patient with atopic dermatitis successfully treated with Upadacitinib: A case report by Katrina D Cirone, Fiona E Lovegrove

“…The development of psoriasis in patients with atopic dermatitis on Dupilumab therapy is believed to occur due to a decrease in T helper 2 activity and resultant dysregulation of the T helper 1 and T helper 17 pathways involved in psoriasis pathogenesis. Upadacitinib, an oral, selective Janus kinase 1 inhibitor, approved for use in moderate-to-severe atopic dermatitis as well as psoriatic arthritis may have a potential role in psoriasis treatment. …”
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Recent Advances in Understanding the Inflammatory Response in Malaria: A Review of the Dual Role of Cytokines by Gabriela Loredana Popa, Mircea Ioan Popa

“…It predominantly occurs in tropical areas where it is transmitted through the bite of an infected Anopheles mosquito. The pathogenesis of malaria is complex and incompletely elucidated. …”
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Transplantation of intestinal microbiota: therapeutic potential at diseases of digestive organs by E. V. Shrayner, S. A. Kurilovich, M. F. Osipenko, V. V. Vlasov

“…Progress in understanding of clinical value of faecal microbiota will transform concept of pathogenesis and treatment of set of diseases.…”
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Diet-Intestinal Microbiota Axis in Osteoarthritis: A Possible Role by Yusheng Li, Wei Luo, Zhenhan Deng, Guanghua Lei

“…Although various person-level risk factors, such as age, sex, and obesity, have been proposed for the pathogenesis of OA, the underlying links between these person-level factors and OA are still enigmatic. …”
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Examining the Choroid in Ocular Inflammation: A Focus on Enhanced Depth Imaging by Abeir Baltmr, Sue Lightman, Oren Tomkins-Netzer

“…The choroid is the vascular layer that supplies the outer retina and is involved in the pathogenesis of several ocular conditions including choroidal tumors, age related macular degeneration, central serous chorioretinopathy, diabetic retinopathy, and uveitis. …”
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Cardiovascular Complications in CKD Patients: Role of Oxidative Stress by Elvira O. Gosmanova, Ngoc-Anh Le

“…We will review the data that support the contribution of oxidative stress in the pathogenesis of CVD in patients with chronic kidney failure.…”
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Evidence for a Potential Role of Metallothioneins in Inflammatory Bowel Diseases by Anouk Waeytens, Martine De Vos, Debby Laukens

“…Recent studies underscore the importance of the damaged epithelial barrier and the dysregulated innate immune system in their pathogenesis. Metallothioneins (MTs) are a family of small proteins with a high and conserved cysteine content that are rapidly upregulated in response to an inflammatory stimulus. …”
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